High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 118 | 415 | | 5291 | 13931 | 133.5 | 31.83 | 201.37 | 181.71 | 100 | 107 | 114 | 119 | 126 | 134 | 144 | 157 | 178 | 0.0743 | 1035 | 1.075 | 91.53 | 27.73 | 2 | 0.0433 | 229 | 0.0025 | 21.43 | 6.360 | 0.2445 | 18826.4 | 2820000 | 448000000 | 75800000000 | 0.4311 | 0.2131 | 0.0015 | 0.0000 | 0.0042 | 0.0000 | 0.0097 | 0.0006 | 0.0303 | 0.0025 | 0.0739 | 0.0239 | 0.1357 | 0.0482 | 0.1636 | 0.0458 | 0.2090 | 0.0658 | 0.3720 | 0.8132 | 0.0012 | 0.0000 | 0.0028 | 0.0000 | 0.0044 | 0.0000 | 0.0131 | 0.0009 | 0.0332 | 0.0117 | 0.0592 | 0.0263 | 0.0788 | 0.0152 | 0.1106 | 0.0243 | 0.6966 | 0.9216 | 0.0062 | 0.0078 | 0.0175 | 0.0337 | 0.0287 | 0.0285 | 0.0585 | 0.0933 | 0.1181 | 0.1917 | 0.1694 | 0.1839 | 0.1201 | 0.1503 | 0.1427 | 0.1554 | 0.3388 | 0.1554 | 0.0072 | 0.0031 | 0.0143 | 0.0371 | 0.0809 | 0.1314 | 0.1033 | 0.1404 | 0.4823 | 25 | 47 | 73 | 108 | 146 | 194 | 256 | 337 | 458 | 0.0034 | 64.02 | 6.918 | 0.3096 | 73564.5 | 36500000 | 22100000000 | 15400000000000 | 0.6227 | 0.0824 | 0.0134 | 0.0036 | 0.0711 | 0.0072 | 0.1619 | 0.0323 | 0.1753 | 0.0736 | 0.1984 | 0.1406 | 0.1681 | 0.1996 | 0.1071 | 0.1572 | 0.0644 | 0.1658 | 0.0403 | 0.2202 | 0.0011 | 0.0011 | 0.0023 | 0.0013 | 0.0063 | 0.0053 | 0.0173 | 0.0127 | 0.0541 | 0.0396 | 0.0851 | 0.0756 | 0.0699 | 0.0574 | 0.0977 | 0.0911 | 0.6663 | 0.7158 | 0.0014 | 0.0014 | 0.0032 | 0.0035 | 0.0083 | 0.0127 | 0.0236 | 0.0343 | 0.0730 | 0.0863 | 0.1137 | 0.1284 | 0.0955 | 0.1055 | 0.1286 | 0.1320 | 0.5528 | 0.4959 | 0.0017 | 0.0045 | 0.0102 | 0.0202 | 0.0633 | 0.0900 | 0.0787 | 0.1201 | 0.6112 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 935 | 650 | | 4467 | 9610 | 94.8 | 24.92 | 207.00 | 159.98 | 69 | 75 | 80 | 84 | 89 | 95 | 102 | 111 | 128 | 0.0728 | 700 | 0.935 | 58.80 | 21.38 | 2 | 0.0374 | 167 | 0.0023 | 22.65 | 6.438 | 0.2515 | 9610.2 | 1050000 | 124000000 | 15700000000 | 0.4444 | 0.2134 | 0.0007 | 0.0000 | 0.0055 | 0.0010 | 0.0092 | 0.0005 | 0.0283 | 0.0039 | 0.0881 | 0.0217 | 0.1418 | 0.0440 | 0.1686 | 0.0426 | 0.1851 | 0.0733 | 0.3728 | 0.8130 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0048 | 0.0000 | 0.0127 | 0.0016 | 0.0469 | 0.0122 | 0.0720 | 0.0228 | 0.0813 | 0.0176 | 0.1042 | 0.0375 | 0.6764 | 0.9083 | 0.0098 | 0.0137 | 0.0147 | 0.0000 | 0.0244 | 0.0192 | 0.0452 | 0.0658 | 0.1345 | 0.1699 | 0.1516 | 0.2000 | 0.1186 | 0.1151 | 0.1528 | 0.1699 | 0.3484 | 0.2466 | 0.0039 | 0.0055 | 0.0171 | 0.0473 | 0.0892 | 0.1244 | 0.1007 | 0.1172 | 0.4948 | 54 | 84 | 111 | 137 | 168 | 203 | 242 | 303 | 400 | 0.0032 | 28.25 | 6.373 | 0.3196 | 68440.7 | 32700000 | 20600000000 | 15800000000000 | 0.5401 | 0.1476 | 0.0155 | 0.0007 | 0.0447 | 0.0007 | 0.1182 | 0.0190 | 0.1771 | 0.0542 | 0.2087 | 0.1259 | 0.1908 | 0.1667 | 0.1258 | 0.1621 | 0.0810 | 0.1828 | 0.0382 | 0.2878 | 0.0008 | 0.0002 | 0.0010 | 0.0003 | 0.0045 | 0.0026 | 0.0207 | 0.0082 | 0.0649 | 0.0465 | 0.1107 | 0.0798 | 0.0944 | 0.0796 | 0.1265 | 0.1118 | 0.5765 | 0.6712 | 0.0018 | 0.0019 | 0.0080 | 0.0062 | 0.0123 | 0.0162 | 0.0355 | 0.0380 | 0.0952 | 0.1102 | 0.1509 | 0.1501 | 0.0955 | 0.1083 | 0.1404 | 0.1406 | 0.4604 | 0.4285 | 0.0005 | 0.0013 | 0.0099 | 0.0259 | 0.0863 | 0.1255 | 0.0978 | 0.1408 | 0.5120 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 145 | 220 | | 5756 | 11661 | 118.5 | 36.39 | 167.20 | 124.25 | 81 | 90 | 98 | 104 | 111 | 118 | 128 | 143 | 165 | 0.0846 | 986 | 0.856 | 102.96 | 27.00 | 1 | 0.0480 | 276 | 0.0023 | 23.04 | 6.430 | 0.2521 | 15367.1 | 2200000 | 352000000 | 62600000000 | 0.4200 | 0.2279 | 0.0020 | 0.0000 | 0.0029 | 0.0002 | 0.0150 | 0.0010 | 0.0444 | 0.0056 | 0.1120 | 0.0292 | 0.1639 | 0.0606 | 0.1681 | 0.0606 | 0.2099 | 0.0964 | 0.2818 | 0.7463 | 0.0014 | 0.0000 | 0.0009 | 0.0000 | 0.0050 | 0.0007 | 0.0159 | 0.0020 | 0.0515 | 0.0182 | 0.0735 | 0.0309 | 0.0871 | 0.0309 | 0.1288 | 0.0545 | 0.6358 | 0.8628 | 0.0043 | 0.0018 | 0.0130 | 0.0107 | 0.0260 | 0.0178 | 0.0582 | 0.0516 | 0.1094 | 0.1335 | 0.1432 | 0.2046 | 0.1102 | 0.1174 | 0.1363 | 0.1459 | 0.3993 | 0.3167 | 0.0030 | 0.0057 | 0.0174 | 0.0449 | 0.0858 | 0.1233 | 0.1054 | 0.1337 | 0.4808 | 25 | 50 | 81 | 110 | 144 | 177 | 218 | 274 | 343 | 0.0021 | 46.18 | 7.043 | 0.2601 | 43391.7 | 14100000 | 5330000000 | 2240000000000 | 0.5309 | 0.1392 | 0.0066 | 0.0007 | 0.0509 | 0.0066 | 0.1329 | 0.0201 | 0.1554 | 0.0531 | 0.1718 | 0.1357 | 0.1718 | 0.1713 | 0.1337 | 0.1501 | 0.1001 | 0.1692 | 0.0766 | 0.2933 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0047 | 0.0031 | 0.0146 | 0.0122 | 0.0480 | 0.0427 | 0.0812 | 0.0603 | 0.0796 | 0.0606 | 0.1017 | 0.0883 | 0.6681 | 0.7316 | 0.0018 | 0.0022 | 0.0028 | 0.0073 | 0.0117 | 0.0105 | 0.0273 | 0.0350 | 0.0734 | 0.0815 | 0.1175 | 0.1238 | 0.0948 | 0.0986 | 0.1233 | 0.1371 | 0.5474 | 0.5040 | 0.0018 | 0.0034 | 0.0086 | 0.0243 | 0.0633 | 0.0955 | 0.0865 | 0.1196 | 0.5971 | ||
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1167 | 689 | | 6111 | 11010 | 86.5 | 25.63 | 194.11 | 227.36 | 55 | 64 | 71 | 78 | 84 | 91 | 98 | 107 | 121 | 0.0750 | 826 | 0.733 | 215.47 | 54.20 | 4 | 0.0928 | 567 | 0.0034 | 11.76 | 5.994 | 0.3193 | 8137.3 | 828575 | 90900000 | 10700000000 | 0.4313 | 0.2183 | 0.0010 | 0.0004 | 0.0045 | 0.0006 | 0.0156 | 0.0018 | 0.0448 | 0.0075 | 0.1171 | 0.0342 | 0.1801 | 0.0744 | 0.1674 | 0.0795 | 0.1944 | 0.1213 | 0.2751 | 0.6804 | 0.0004 | 0.0004 | 0.0011 | 0.0000 | 0.0033 | 0.0004 | 0.0100 | 0.0028 | 0.0462 | 0.0179 | 0.0736 | 0.0369 | 0.0694 | 0.0341 | 0.1040 | 0.0529 | 0.6918 | 0.8547 | 0.0057 | 0.0065 | 0.0086 | 0.0161 | 0.0179 | 0.0581 | 0.0622 | 0.1113 | 0.1237 | 0.1597 | 0.1587 | 0.1968 | 0.1244 | 0.1323 | 0.1494 | 0.1419 | 0.3495 | 0.1774 | 0.0020 | 0.0037 | 0.0116 | 0.0317 | 0.0810 | 0.1161 | 0.1045 | 0.1324 | 0.5170 | 14 | 18 | 27 | 51 | 94 | 159 | 248 | 359 | 533 | 0.0198 | 121.90 | 6.448 | 0.3047 | 89366.6 | 55800000 | 41100000000 | 34000000000000 | 0.4757 | 0.1749 | 0.0822 | 0.0030 | 0.2716 | 0.0287 | 0.3153 | 0.2000 | 0.1093 | 0.1713 | 0.1103 | 0.1866 | 0.0562 | 0.1683 | 0.0416 | 0.0896 | 0.0083 | 0.0733 | 0.0052 | 0.0792 | 0.0007 | 0.0002 | 0.0002 | 0.0008 | 0.0034 | 0.0016 | 0.0104 | 0.0093 | 0.0707 | 0.0599 | 0.1227 | 0.1136 | 0.0860 | 0.0717 | 0.1146 | 0.1087 | 0.5914 | 0.6343 | 0.0006 | 0.0007 | 0.0014 | 0.0039 | 0.0046 | 0.0079 | 0.0149 | 0.0201 | 0.0879 | 0.0911 | 0.1479 | 0.1601 | 0.0948 | 0.0999 | 0.1390 | 0.1443 | 0.5088 | 0.4721 | 0.0003 | 0.0018 | 0.0059 | 0.0132 | 0.0749 | 0.1391 | 0.0892 | 0.1302 | 0.5455 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1013 | 776 | | 4132 | 4149 | 163.6 | 45.21 | 162.20 | 159.12 | 116 | 127 | 136 | 145 | 155 | 166 | 178 | 197 | 224 | 0.1347 | 559 | 1.127 | 94.07 | 29.83 | 1 | 0.0549 | 227 | 0.0016 | 35.59 | 6.765 | 0.2144 | 28795.0 | 5490000 | 1140000000 | 256000000000 | 0.3736 | 0.2711 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0097 | 0.0000 | 0.0313 | 0.0016 | 0.1031 | 0.0289 | 0.1793 | 0.0586 | 0.1696 | 0.0559 | 0.1608 | 0.0805 | 0.3449 | 0.7744 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0126 | 0.0012 | 0.0426 | 0.0173 | 0.0765 | 0.0318 | 0.0726 | 0.0202 | 0.0833 | 0.0333 | 0.7089 | 0.8961 | 0.0012 | 0.0057 | 0.0060 | 0.0028 | 0.0193 | 0.0342 | 0.0712 | 0.1026 | 0.1351 | 0.1852 | 0.1689 | 0.1538 | 0.1074 | 0.1254 | 0.1544 | 0.1282 | 0.3366 | 0.2621 | 0.0006 | 0.0029 | 0.0081 | 0.0400 | 0.0737 | 0.1398 | 0.0986 | 0.1119 | 0.5244 | 19 | 39 | 59 | 79 | 105 | 140 | 187 | 267 | 405 | 0.0058 | 51.95 | 6.395 | 0.3274 | 51621.9 | 23000000 | 12200000000 | 7280000000000 | 0.4555 | 0.1933 | 0.0214 | 0.0008 | 0.1246 | 0.0084 | 0.2206 | 0.0489 | 0.1851 | 0.1281 | 0.1495 | 0.1778 | 0.1388 | 0.1912 | 0.0747 | 0.1272 | 0.0534 | 0.1348 | 0.0320 | 0.1828 | 0.0006 | 0.0000 | 0.0011 | 0.0036 | 0.0034 | 0.0027 | 0.0238 | 0.0173 | 0.0747 | 0.0600 | 0.1065 | 0.1055 | 0.0821 | 0.0673 | 0.1121 | 0.1014 | 0.5957 | 0.6421 | 0.0017 | 0.0000 | 0.0033 | 0.0040 | 0.0083 | 0.0049 | 0.0282 | 0.0346 | 0.0698 | 0.0949 | 0.1412 | 0.1215 | 0.0947 | 0.1057 | 0.1204 | 0.1364 | 0.5324 | 0.4980 | 0.0007 | 0.0034 | 0.0103 | 0.0248 | 0.0765 | 0.1254 | 0.0827 | 0.1158 | 0.5603 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 855 | 618 | | 6392 | 8692 | 565.9 | 136.42 | 151.51 | 154.48 | 405 | 449 | 487 | 519 | 551 | 583 | 618 | 669 | 747 | 0.0962 | 836 | 1.181 | 149.16 | 56.30 | 1 | 0.0601 | 384 | 0.0005 | 84.49 | 7.736 | 0.1296 | 338887.0 | 215000000 | 144000000000 | 102000000000000 | 0.4381 | 0.2035 | 0.0003 | 0.0000 | 0.0013 | 0.0002 | 0.0021 | 0.0003 | 0.0167 | 0.0026 | 0.0632 | 0.0204 | 0.1182 | 0.0408 | 0.1292 | 0.0333 | 0.1665 | 0.0493 | 0.5027 | 0.8530 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0002 | 0.0063 | 0.0016 | 0.0281 | 0.0131 | 0.0505 | 0.0215 | 0.0583 | 0.0156 | 0.0783 | 0.0233 | 0.7769 | 0.9246 | 0.0026 | 0.0102 | 0.0061 | 0.0051 | 0.0104 | 0.0255 | 0.0494 | 0.0561 | 0.1223 | 0.1378 | 0.1405 | 0.2168 | 0.1119 | 0.1173 | 0.1474 | 0.1505 | 0.4094 | 0.2806 | 0.0014 | 0.0034 | 0.0085 | 0.0263 | 0.0650 | 0.1026 | 0.0988 | 0.1173 | 0.5766 | 16 | 30 | 48 | 69 | 98 | 135 | 183 | 254 | 363 | 0.0144 | 28.33 | 5.755 | 0.4071 | 46815.8 | 20900000 | 11800000000 | 7940000000000 | 0.4493 | 0.1881 | 0.0467 | 0.0022 | 0.1642 | 0.0178 | 0.2921 | 0.0975 | 0.1659 | 0.1300 | 0.1366 | 0.1820 | 0.0977 | 0.1971 | 0.0467 | 0.1443 | 0.0285 | 0.1109 | 0.0216 | 0.1183 | 0.0000 | 0.0000 | 0.0016 | 0.0020 | 0.0024 | 0.0004 | 0.0199 | 0.0124 | 0.0749 | 0.0587 | 0.1204 | 0.0974 | 0.0863 | 0.0733 | 0.1178 | 0.1060 | 0.5768 | 0.6498 | 0.0004 | 0.0009 | 0.0008 | 0.0023 | 0.0046 | 0.0072 | 0.0347 | 0.0432 | 0.1206 | 0.1292 | 0.1583 | 0.1567 | 0.0946 | 0.1094 | 0.1389 | 0.1531 | 0.4472 | 0.3980 | 0.0010 | 0.0016 | 0.0035 | 0.0247 | 0.0958 | 0.1380 | 0.0986 | 0.1415 | 0.4954 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 751 | 267 | | 3996 | 13985 | 152.2 | 33.85 | 141.01 | 145.07 | 113 | 124 | 133 | 140 | 148 | 155 | 165 | 178 | 196 | 0.0633 | 885 | 1.001 | 83.55 | 24.08 | 2 | 0.0488 | 195 | 0.0021 | 21.13 | 6.445 | 0.2487 | 24325.1 | 4090000 | 723000000 | 135000000000 | 0.4071 | 0.2421 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0046 | 0.0000 | 0.0217 | 0.0008 | 0.0685 | 0.0210 | 0.1371 | 0.0445 | 0.1470 | 0.0450 | 0.1702 | 0.0623 | 0.4497 | 0.8264 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0072 | 0.0003 | 0.0302 | 0.0141 | 0.0688 | 0.0303 | 0.0676 | 0.0197 | 0.0894 | 0.0351 | 0.7352 | 0.9005 | 0.0015 | 0.0049 | 0.0160 | 0.0099 | 0.0248 | 0.0049 | 0.0758 | 0.1626 | 0.1487 | 0.1576 | 0.1662 | 0.1921 | 0.1122 | 0.1379 | 0.1327 | 0.1281 | 0.3222 | 0.2020 | 0.0033 | 0.0044 | 0.0116 | 0.0311 | 0.0843 | 0.1337 | 0.0943 | 0.1281 | 0.5092 | 19 | 33 | 50 | 68 | 90 | 118 | 157 | 223 | 339 | 0.0069 | 33.28 | 6.213 | 0.3970 | 40926.9 | 17700000 | 9520000000 | 5890000000000 | 0.6594 | 0.0769 | 0.0120 | 0.0022 | 0.0718 | 0.0095 | 0.1486 | 0.0217 | 0.1626 | 0.0638 | 0.1950 | 0.1371 | 0.1406 | 0.1875 | 0.1077 | 0.1501 | 0.0803 | 0.1521 | 0.0813 | 0.2760 | 0.0019 | 0.0005 | 0.0029 | 0.0029 | 0.0075 | 0.0052 | 0.0196 | 0.0142 | 0.0618 | 0.0479 | 0.0945 | 0.0817 | 0.0723 | 0.0641 | 0.1133 | 0.0906 | 0.6263 | 0.6929 | 0.0008 | 0.0003 | 0.0044 | 0.0049 | 0.0072 | 0.0097 | 0.0294 | 0.0346 | 0.0744 | 0.0822 | 0.1224 | 0.1275 | 0.0945 | 0.1005 | 0.1237 | 0.1287 | 0.5430 | 0.5117 | 0.0017 | 0.0042 | 0.0089 | 0.0256 | 0.0701 | 0.1033 | 0.0830 | 0.1114 | 0.5917 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 956 | 481 | | 1986 | 9878 | 45.3 | 11.48 | 35.21 | 55.46 | 30 | 34 | 39 | 42 | 45 | 48 | 51 | 56 | 60 | 0.0765 | 756 | 0.806 | 36.77 | 10.44 | 2 | 0.0539 | 107 | 0.0083 | 3.62 | 5.056 | 0.4649 | 2186.4 | 111365 | 5950000 | 331000000 | 0.4003 | 0.2238 | 0.0019 | 0.0000 | 0.0028 | 0.0011 | 0.0131 | 0.0045 | 0.0327 | 0.0129 | 0.0515 | 0.0286 | 0.0776 | 0.0432 | 0.1132 | 0.0510 | 0.1506 | 0.0875 | 0.5566 | 0.7712 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0039 | 0.0021 | 0.0129 | 0.0078 | 0.0207 | 0.0204 | 0.0311 | 0.0266 | 0.0317 | 0.0282 | 0.0498 | 0.0408 | 0.8485 | 0.8741 | 0.0084 | 0.0229 | 0.0231 | 0.0458 | 0.0231 | 0.1069 | 0.0273 | 0.0992 | 0.0588 | 0.0840 | 0.0546 | 0.0992 | 0.0777 | 0.1603 | 0.1387 | 0.1221 | 0.5882 | 0.2595 | 0.0019 | 0.0058 | 0.0145 | 0.0270 | 0.0462 | 0.0568 | 0.0751 | 0.0934 | 0.6792 | 12 | 14 | 15 | 16 | 18 | 22 | 28 | 39 | 66 | 0.3765 | 2.00 | 2.023 | 0.8544 | 4314.9 | 1380000 | 642000000 | 351000000000 | 0.5769 | 0.1123 | 0.0338 | 0.0176 | 0.0938 | 0.0290 | 0.1429 | 0.0522 | 0.1420 | 0.0746 | 0.1488 | 0.1228 | 0.1505 | 0.1485 | 0.1234 | 0.1246 | 0.1023 | 0.1456 | 0.0626 | 0.2849 | 0.0033 | 0.0112 | 0.0063 | 0.0160 | 0.0139 | 0.0227 | 0.0325 | 0.0284 | 0.0634 | 0.0516 | 0.0933 | 0.0672 | 0.0863 | 0.0700 | 0.1218 | 0.1011 | 0.5792 | 0.6317 | 0.0016 | 0.0048 | 0.0055 | 0.0068 | 0.0131 | 0.0109 | 0.0344 | 0.0505 | 0.1071 | 0.1038 | 0.1301 | 0.1633 | 0.0945 | 0.1004 | 0.1519 | 0.1346 | 0.4617 | 0.4249 | 0.0047 | 0.0060 | 0.0125 | 0.0324 | 0.0824 | 0.1100 | 0.0846 | 0.1342 | 0.5332 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 684 | 361 | | 399 | 6206 | 58.4 | 9.74 | 24.73 | 66.86 | 46 | 49 | 52 | 54 | 57 | 61 | 64 | 69 | 72 | 0.1017 | 631 | 0.682 | 36.24 | 8.54 | 1 | 0.2607 | 104 | 0.0248 | 2.23 | 3.908 | 0.5277 | 3503.6 | 215851 | 13600000 | 881000000 | 0.3536 | 0.2676 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0071 | 0.0000 | 0.0426 | 0.0101 | 0.0922 | 0.0628 | 0.1525 | 0.0678 | 0.1489 | 0.0653 | 0.1915 | 0.0879 | 0.3617 | 0.7060 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0225 | 0.0100 | 0.0535 | 0.0627 | 0.0817 | 0.0677 | 0.0789 | 0.0652 | 0.1042 | 0.0677 | 0.6563 | 0.7268 | 0.0137 | 1.0000 | 0.0000 | 0.0000 | 0.0274 | 0.0000 | 0.0822 | 0.0000 | 0.0822 | 0.0000 | 0.1781 | 0.0000 | 0.1370 | 0.0000 | 0.2055 | 0.0000 | 0.2740 | 0.0000 | 0.0053 | 0.0053 | 0.0159 | 0.0265 | 0.0635 | 0.1111 | 0.1058 | 0.0899 | 0.5767 | 5 | 6 | 7 | 8 | 9 | 10 | 13 | 18 | 40 | 0.3348 | 9.79 | 2.064 | 0.7707 | 5081.6 | 2730000 | 1940000000 | 1570000000000 | 0.6341 | 0.0846 | 0.0349 | 0.0330 | 0.1163 | 0.0366 | 0.1453 | 0.0425 | 0.1628 | 0.0837 | 0.2006 | 0.1262 | 0.1919 | 0.1498 | 0.1163 | 0.1462 | 0.0233 | 0.1686 | 0.0087 | 0.2134 | 0.0053 | 0.0181 | 0.0079 | 0.0194 | 0.0184 | 0.0148 | 0.0202 | 0.0258 | 0.0746 | 0.0523 | 0.0886 | 0.0690 | 0.0912 | 0.0800 | 0.1202 | 0.1052 | 0.5737 | 0.6155 | 0.0025 | 0.0028 | 0.0013 | 0.0000 | 0.0088 | 0.0043 | 0.0251 | 0.0256 | 0.0842 | 0.0954 | 0.1256 | 0.1439 | 0.0942 | 0.1068 | 0.1344 | 0.1296 | 0.5239 | 0.4915 | 0.0022 | 0.0098 | 0.0065 | 0.0271 | 0.0869 | 0.0912 | 0.0988 | 0.1325 | 0.5451 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 137 | 324 | | 5641 | 20747 | 281.5 | 64.71 | 102.70 | 136.65 | 202 | 225 | 243 | 262 | 277 | 293 | 311 | 335 | 366 | 0.0556 | 1153 | 0.979 | 115.25 | 26.87 | 1 | 0.0456 | 257 | 0.0006 | 71.66 | 7.549 | 0.1440 | 83449.7 | 26000000 | 8510000000 | 2920000000000 | 0.4017 | 0.2486 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0000 | 0.0232 | 0.0027 | 0.0713 | 0.0198 | 0.1447 | 0.0392 | 0.1676 | 0.0472 | 0.1783 | 0.0677 | 0.4103 | 0.8235 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0102 | 0.0011 | 0.0291 | 0.0141 | 0.0555 | 0.0255 | 0.0700 | 0.0224 | 0.0851 | 0.0349 | 0.7483 | 0.9020 | 0.0009 | 0.0074 | 0.0085 | 0.0257 | 0.0180 | 0.0662 | 0.0722 | 0.1029 | 0.1472 | 0.1838 | 0.1918 | 0.1618 | 0.1149 | 0.1360 | 0.1434 | 0.1140 | 0.3029 | 0.2022 | 0.0023 | 0.0015 | 0.0072 | 0.0281 | 0.0795 | 0.1228 | 0.1049 | 0.1327 | 0.5209 | 11 | 14 | 17 | 23 | 35 | 63 | 115 | 185 | 286 | 0.0458 | 14.71 | 4.863 | 0.5260 | 29220.6 | 12900000 | 7580000000 | 5510000000000 | 0.5276 | 0.1342 | 0.0999 | 0.0045 | 0.3282 | 0.0294 | 0.3393 | 0.1714 | 0.1201 | 0.2314 | 0.0597 | 0.2369 | 0.0285 | 0.1756 | 0.0132 | 0.0762 | 0.0090 | 0.0458 | 0.0021 | 0.0287 | 0.0003 | 0.0002 | 0.0004 | 0.0007 | 0.0014 | 0.0014 | 0.0118 | 0.0117 | 0.0724 | 0.0573 | 0.1165 | 0.1003 | 0.0799 | 0.0698 | 0.1094 | 0.0976 | 0.6080 | 0.6610 | 0.0005 | 0.0006 | 0.0012 | 0.0025 | 0.0034 | 0.0047 | 0.0207 | 0.0211 | 0.0878 | 0.0967 | 0.1435 | 0.1663 | 0.0940 | 0.0978 | 0.1317 | 0.1352 | 0.5172 | 0.4752 | 0.0002 | 0.0006 | 0.0024 | 0.0191 | 0.0743 | 0.1338 | 0.0863 | 0.1178 | 0.5656 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 224 | 664 | | 23929 | 53243 | 235.7 | 71.53 | 198.53 | 308.24 | 140 | 172 | 197 | 217 | 235 | 254 | 274 | 298 | 328 | 0.0344 | 1829 | 0.641 | 165.59 | 39.45 | 7 | 0.0212 | 508 | 0.0005 | 51.67 | 7.813 | 0.1685 | 60653.4 | 16700000 | 4890000000 | 1500000000000 | 0.4168 | 0.2169 | 0.0013 | 0.0002 | 0.0025 | 0.0005 | 0.0085 | 0.0016 | 0.0313 | 0.0057 | 0.0797 | 0.0252 | 0.1433 | 0.0530 | 0.1429 | 0.0600 | 0.1764 | 0.0821 | 0.4142 | 0.7718 | 0.0006 | 0.0002 | 0.0010 | 0.0003 | 0.0020 | 0.0007 | 0.0074 | 0.0028 | 0.0227 | 0.0123 | 0.0429 | 0.0258 | 0.0415 | 0.0237 | 0.0600 | 0.0321 | 0.8218 | 0.9020 | 0.0018 | 0.0071 | 0.0045 | 0.0102 | 0.0154 | 0.0252 | 0.0432 | 0.0885 | 0.0873 | 0.1322 | 0.1280 | 0.1588 | 0.1107 | 0.1225 | 0.1340 | 0.1433 | 0.4752 | 0.3123 | 0.0008 | 0.0021 | 0.0061 | 0.0159 | 0.0445 | 0.0832 | 0.0794 | 0.1112 | 0.6569 | 15 | 19 | 23 | 31 | 50 | 98 | 191 | 331 | 581 | 0.0417 | 56.38 | 5.497 | 0.4839 | 134424.0 | 143000000 | 193000000000 | 306000000000000 | 0.3773 | 0.2809 | 0.0950 | 0.0031 | 0.2742 | 0.0340 | 0.2930 | 0.1903 | 0.1326 | 0.1923 | 0.0925 | 0.1954 | 0.0613 | 0.1542 | 0.0320 | 0.0969 | 0.0146 | 0.0718 | 0.0047 | 0.0620 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0028 | 0.0019 | 0.0151 | 0.0118 | 0.0675 | 0.0598 | 0.1124 | 0.0965 | 0.0779 | 0.0655 | 0.1108 | 0.0997 | 0.6126 | 0.6642 | 0.0005 | 0.0011 | 0.0017 | 0.0024 | 0.0055 | 0.0069 | 0.0244 | 0.0283 | 0.0804 | 0.0894 | 0.1332 | 0.1361 | 0.0938 | 0.0992 | 0.1210 | 0.1267 | 0.5395 | 0.5097 | 0.0004 | 0.0016 | 0.0031 | 0.0214 | 0.0760 | 0.1177 | 0.0887 | 0.1187 | 0.5725 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 689 | | 7600 | 15811 | 210.9 | 43.78 | 142.17 | 171.25 | 159 | 173 | 185 | 196 | 207 | 218 | 230 | 245 | 269 | 0.0623 | 985 | 1.140 | 88.32 | 39.01 | 1 | 0.0330 | 251 | 0.0011 | 39.63 | 7.083 | 0.1887 | 46382.0 | 10600000 | 2540000000 | 632000000000 | 0.4649 | 0.1876 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0031 | 0.0000 | 0.0156 | 0.0013 | 0.0581 | 0.0167 | 0.1363 | 0.0365 | 0.1516 | 0.0327 | 0.1761 | 0.0584 | 0.4584 | 0.8545 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0074 | 0.0004 | 0.0307 | 0.0110 | 0.0643 | 0.0228 | 0.0646 | 0.0137 | 0.0939 | 0.0247 | 0.7375 | 0.9274 | 0.0050 | 0.0238 | 0.0058 | 0.0149 | 0.0284 | 0.0387 | 0.0984 | 0.1310 | 0.1418 | 0.1786 | 0.1818 | 0.1994 | 0.0992 | 0.1012 | 0.1276 | 0.1250 | 0.3119 | 0.1875 | 0.0009 | 0.0020 | 0.0111 | 0.0386 | 0.0873 | 0.1384 | 0.1199 | 0.1335 | 0.4684 | 11 | 13 | 15 | 21 | 53 | 120 | 192 | 279 | 392 | 0.0646 | 26.36 | 5.217 | 0.4922 | 49534.8 | 23000000 | 12600000000 | 7870000000000 | 0.5544 | 0.1062 | 0.0575 | 0.0021 | 0.2553 | 0.0185 | 0.3274 | 0.1627 | 0.1596 | 0.1906 | 0.0883 | 0.1964 | 0.0624 | 0.1886 | 0.0300 | 0.1011 | 0.0130 | 0.0719 | 0.0065 | 0.0682 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0005 | 0.0010 | 0.0079 | 0.0052 | 0.0517 | 0.0451 | 0.0963 | 0.0833 | 0.0703 | 0.0593 | 0.0991 | 0.0835 | 0.6739 | 0.7223 | 0.0002 | 0.0004 | 0.0013 | 0.0015 | 0.0029 | 0.0043 | 0.0140 | 0.0201 | 0.0689 | 0.0788 | 0.1235 | 0.1391 | 0.0936 | 0.0936 | 0.1214 | 0.1176 | 0.5743 | 0.5445 | 0.0000 | 0.0003 | 0.0017 | 0.0095 | 0.0610 | 0.1104 | 0.0758 | 0.1149 | 0.6263 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 227 | 700 | | 2457 | 15737 | 289.2 | 101.50 | 9.59 | 3.09 | 185 | 205 | 224 | 243 | 262 | 282 | 308 | 358 | 452 | 0.0555 | 874 | 1.038 | 40.80 | 14.42 | 1 | 0.0456 | 112 | 0.0046 | 7.54 | 5.814 | 0.3959 | 93934.6 | 34400000 | 14000000000 | 6220000000000 | 0.3996 | 0.2284 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0010 | 0.0200 | 0.0095 | 0.0763 | 0.0322 | 0.1117 | 0.0548 | 0.0981 | 0.0497 | 0.1154 | 0.0724 | 0.5722 | 0.7804 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0008 | 0.0110 | 0.0064 | 0.0318 | 0.0187 | 0.0434 | 0.0314 | 0.0446 | 0.0263 | 0.0532 | 0.0403 | 0.8128 | 0.8760 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0019 | 0.0027 | 0.0206 | 0.0247 | 0.0468 | 0.0630 | 0.0880 | 0.0904 | 0.0637 | 0.0685 | 0.0787 | 0.0986 | 0.6966 | 0.6521 | 0.0011 | 0.0022 | 0.0043 | 0.0183 | 0.0539 | 0.0766 | 0.0583 | 0.0798 | 0.7055 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 12 | 14 | 0.0103 | 12.47 | 4.932 | 0.3085 | 101.5 | 1173.91 | 14746.7 | 200713 | 0.4806 | 0.1663 | 0.0121 | 0.0008 | 0.0519 | 0.0024 | 0.1150 | 0.0081 | 0.1984 | 0.0215 | 0.2311 | 0.0482 | 0.1959 | 0.0974 | 0.1331 | 0.1901 | 0.0517 | 0.3239 | 0.0108 | 0.3077 | 0.0032 | 0.0001 | 0.0147 | 0.0004 | 0.0283 | 0.0024 | 0.0519 | 0.0078 | 0.0814 | 0.0224 | 0.1134 | 0.0398 | 0.1727 | 0.0801 | 0.2397 | 0.2135 | 0.2946 | 0.6336 | 0.0921 | 0.2202 | 0.1323 | 0.1939 | 0.1418 | 0.1653 | 0.1471 | 0.1289 | 0.1473 | 0.1008 | 0.1225 | 0.0776 | 0.0936 | 0.0519 | 0.0695 | 0.0328 | 0.0537 | 0.0286 | 0.0234 | 0.0575 | 0.0810 | 0.1141 | 0.1428 | 0.1680 | 0.1726 | 0.1435 | 0.0970 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 607 | 650 | | 808 | 9723 | 822.7 | 285.42 | 10.47 | 10.85 | 493 | 549 | 610 | 675 | 765 | 856 | 972 | 1125 | 1261 | 0.0725 | 705 | 0.565 | 32.65 | 5.00 | 1 | 0.1114 | 90 | 0.0018 | 33.14 | 6.417 | 0.1590 | 758238.0 | 769000000 | 841000000000 | 970000000000000 | 0.3548 | 0.2711 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0017 | 0.1057 | 0.0517 | 0.2453 | 0.1138 | 0.1057 | 0.0552 | 0.1811 | 0.0845 | 0.3585 | 0.6931 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0400 | 0.0332 | 0.0700 | 0.0622 | 0.0280 | 0.0249 | 0.0600 | 0.0443 | 0.8000 | 0.8340 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0070 | 0.0681 | 0.0839 | 0.1021 | 0.1259 | 0.0340 | 0.0420 | 0.0681 | 0.0909 | 0.7277 | 0.6504 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0538 | 0.0595 | 0.0482 | 0.0680 | 0.7620 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 17 | 0.1294 | 0.43 | 1.360 | 0.4878 | 227.2 | 11518.1 | 951002 | 99400000 | 0.4627 | 0.1724 | 0.0445 | 0.0009 | 0.1116 | 0.0040 | 0.1533 | 0.0184 | 0.1904 | 0.0460 | 0.1793 | 0.1011 | 0.1539 | 0.1744 | 0.0974 | 0.2117 | 0.0526 | 0.2479 | 0.0170 | 0.1955 | 0.0262 | 0.0002 | 0.0614 | 0.0026 | 0.0785 | 0.0118 | 0.0849 | 0.0295 | 0.0861 | 0.0688 | 0.0922 | 0.1203 | 0.0968 | 0.1483 | 0.1240 | 0.1897 | 0.3498 | 0.4287 | 0.0345 | 0.0237 | 0.0367 | 0.0266 | 0.0434 | 0.0180 | 0.0579 | 0.0633 | 0.0880 | 0.0957 | 0.1030 | 0.1165 | 0.0935 | 0.1043 | 0.1253 | 0.1288 | 0.4176 | 0.4230 | 0.0560 | 0.0567 | 0.0599 | 0.0685 | 0.0868 | 0.0890 | 0.1015 | 0.1209 | 0.3606 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1199 | 269 | | 6858 | 34380 | 182.5 | 52.85 | 124.86 | 199.10 | 122 | 141 | 154 | 165 | 177 | 190 | 204 | 222 | 256 | 0.0332 | 1142 | 0.787 | 31.00 | 8.06 | 3 | 0.0117 | 80 | 0.0011 | 37.84 | 7.176 | 0.1947 | 36107.4 | 7670000 | 1740000000 | 418000000000 | 0.4164 | 0.2188 | 0.0008 | 0.0000 | 0.0016 | 0.0003 | 0.0074 | 0.0003 | 0.0251 | 0.0031 | 0.0740 | 0.0238 | 0.1294 | 0.0417 | 0.1524 | 0.0466 | 0.1762 | 0.0732 | 0.4332 | 0.8108 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0012 | 0.0321 | 0.0128 | 0.0530 | 0.0208 | 0.0614 | 0.0187 | 0.0821 | 0.0317 | 0.7569 | 0.9147 | 0.0035 | 0.0089 | 0.0090 | 0.0089 | 0.0097 | 0.0222 | 0.0520 | 0.0532 | 0.0929 | 0.1064 | 0.1283 | 0.1241 | 0.0999 | 0.1004 | 0.1200 | 0.1241 | 0.4847 | 0.4520 | 0.0016 | 0.0038 | 0.0074 | 0.0272 | 0.0579 | 0.0886 | 0.0908 | 0.1164 | 0.6063 | 17 | 21 | 25 | 29 | 35 | 48 | 91 | 194 | 364 | 0.0577 | 29.38 | 4.737 | 0.5383 | 55230.0 | 41200000 | 40500000000 | 47700000000000 | 0.3925 | 0.2378 | 0.1380 | 0.0050 | 0.3601 | 0.0465 | 0.2981 | 0.2724 | 0.1080 | 0.2297 | 0.0587 | 0.1914 | 0.0244 | 0.1219 | 0.0089 | 0.0649 | 0.0028 | 0.0419 | 0.0011 | 0.0263 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0019 | 0.0020 | 0.0186 | 0.0147 | 0.0758 | 0.0670 | 0.1162 | 0.0990 | 0.0798 | 0.0694 | 0.1195 | 0.1071 | 0.5878 | 0.6402 | 0.0002 | 0.0003 | 0.0007 | 0.0022 | 0.0033 | 0.0056 | 0.0256 | 0.0302 | 0.0905 | 0.0964 | 0.1439 | 0.1483 | 0.0934 | 0.1014 | 0.1314 | 0.1378 | 0.5108 | 0.4778 | 0.0002 | 0.0007 | 0.0022 | 0.0238 | 0.0786 | 0.1331 | 0.0854 | 0.1281 | 0.5480 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 318 | 398 | | 21149 | 32393 | 118.4 | 36.13 | 198.09 | 230.96 | 79 | 89 | 97 | 105 | 112 | 121 | 131 | 144 | 166 | 0.0593 | 1920 | 0.736 | 173.25 | 37.64 | 3 | 0.0214 | 452 | 0.0021 | 20.81 | 6.559 | 0.2661 | 15334.3 | 2180000 | 343000000 | 59700000000 | 0.4453 | 0.2046 | 0.0012 | 0.0001 | 0.0027 | 0.0003 | 0.0109 | 0.0011 | 0.0349 | 0.0049 | 0.1040 | 0.0257 | 0.1712 | 0.0574 | 0.1644 | 0.0633 | 0.1813 | 0.0975 | 0.3295 | 0.7498 | 0.0006 | 0.0000 | 0.0013 | 0.0001 | 0.0041 | 0.0008 | 0.0116 | 0.0021 | 0.0381 | 0.0130 | 0.0636 | 0.0258 | 0.0677 | 0.0265 | 0.0964 | 0.0418 | 0.7166 | 0.8899 | 0.0030 | 0.0065 | 0.0063 | 0.0145 | 0.0203 | 0.0187 | 0.0586 | 0.0816 | 0.1155 | 0.1493 | 0.1471 | 0.1968 | 0.1274 | 0.1129 | 0.1298 | 0.1399 | 0.3918 | 0.2799 | 0.0020 | 0.0048 | 0.0084 | 0.0315 | 0.0770 | 0.1122 | 0.0985 | 0.1278 | 0.5378 | 14 | 17 | 25 | 48 | 96 | 167 | 259 | 373 | 535 | 0.0276 | 93.42 | 6.409 | 0.3746 | 92580.9 | 58500000 | 44100000000 | 37800000000000 | 0.5719 | 0.1057 | 0.0647 | 0.0020 | 0.2147 | 0.0220 | 0.2542 | 0.1155 | 0.1479 | 0.1648 | 0.1256 | 0.1968 | 0.0936 | 0.1670 | 0.0523 | 0.1282 | 0.0303 | 0.0948 | 0.0169 | 0.1089 | 0.0004 | 0.0002 | 0.0013 | 0.0011 | 0.0026 | 0.0022 | 0.0119 | 0.0095 | 0.0574 | 0.0487 | 0.0985 | 0.0827 | 0.0773 | 0.0653 | 0.1116 | 0.0939 | 0.6390 | 0.6965 | 0.0004 | 0.0003 | 0.0016 | 0.0021 | 0.0053 | 0.0067 | 0.0183 | 0.0246 | 0.0756 | 0.0872 | 0.1236 | 0.1318 | 0.0932 | 0.1017 | 0.1281 | 0.1345 | 0.5539 | 0.5111 | 0.0007 | 0.0017 | 0.0031 | 0.0149 | 0.0664 | 0.1128 | 0.0859 | 0.1198 | 0.5947 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 902 | 772 | | 9805 | 18751 | 104.4 | 27.00 | 104.60 | 154.09 | 71 | 82 | 90 | 97 | 104 | 110 | 117 | 126 | 139 | 0.0633 | 1186 | 1.212 | 43.08 | 15.81 | 3 | 0.0114 | 112 | 0.0025 | 16.76 | 6.319 | 0.2683 | 11632.2 | 1370000 | 170000000 | 22000000000 | 0.4240 | 0.2204 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0088 | 0.0007 | 0.0337 | 0.0037 | 0.0934 | 0.0179 | 0.1645 | 0.0465 | 0.1821 | 0.0638 | 0.1963 | 0.0903 | 0.3200 | 0.7770 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0001 | 0.0076 | 0.0017 | 0.0290 | 0.0096 | 0.0611 | 0.0214 | 0.0697 | 0.0191 | 0.0939 | 0.0324 | 0.7359 | 0.9158 | 0.0079 | 0.0174 | 0.0153 | 0.0349 | 0.0227 | 0.0654 | 0.0811 | 0.1497 | 0.1293 | 0.1715 | 0.1688 | 0.2035 | 0.1433 | 0.1206 | 0.1539 | 0.1206 | 0.2777 | 0.1163 | 0.0006 | 0.0026 | 0.0102 | 0.0307 | 0.0718 | 0.1201 | 0.1160 | 0.1498 | 0.4982 | 11 | 13 | 15 | 19 | 27 | 52 | 104 | 180 | 312 | 0.1458 | 19.88 | 4.207 | 0.6121 | 34684.3 | 18400000 | 13400000000 | 12900000000000 | 0.5548 | 0.1144 | 0.1016 | 0.0053 | 0.2744 | 0.0473 | 0.2848 | 0.2020 | 0.1392 | 0.1879 | 0.0992 | 0.2113 | 0.0544 | 0.1673 | 0.0200 | 0.0877 | 0.0168 | 0.0513 | 0.0096 | 0.0400 | 0.0003 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0010 | 0.0124 | 0.0106 | 0.0714 | 0.0584 | 0.1103 | 0.0965 | 0.0716 | 0.0610 | 0.1148 | 0.1027 | 0.6169 | 0.6690 | 0.0000 | 0.0002 | 0.0014 | 0.0022 | 0.0034 | 0.0082 | 0.0241 | 0.0253 | 0.0928 | 0.1033 | 0.1418 | 0.1582 | 0.0932 | 0.1072 | 0.1495 | 0.1476 | 0.4938 | 0.4478 | 0.0004 | 0.0007 | 0.0034 | 0.0164 | 0.0820 | 0.1252 | 0.0852 | 0.1331 | 0.5536 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 825 | 684 | | 7651 | 20186 | 434.9 | 80.92 | 100.21 | 97.16 | 337 | 366 | 390 | 409 | 429 | 448 | 471 | 501 | 545 | 0.0502 | 1013 | 1.138 | 102.84 | 33.06 | 1 | 0.0322 | 246 | 0.0009 | 43.02 | 7.234 | 0.1788 | 195716.0 | 91000000 | 43700000000 | 21700000000000 | 0.4528 | 0.2044 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0013 | 0.0003 | 0.0109 | 0.0004 | 0.0464 | 0.0156 | 0.1085 | 0.0248 | 0.1193 | 0.0267 | 0.1502 | 0.0416 | 0.5632 | 0.8906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0047 | 0.0004 | 0.0241 | 0.0132 | 0.0533 | 0.0176 | 0.0554 | 0.0141 | 0.0757 | 0.0217 | 0.7862 | 0.9330 | 0.0026 | 0.0221 | 0.0123 | 0.0608 | 0.0202 | 0.0663 | 0.0792 | 0.1381 | 0.1206 | 0.1547 | 0.1637 | 0.1381 | 0.1021 | 0.1105 | 0.1144 | 0.1050 | 0.3847 | 0.2044 | 0.0011 | 0.0050 | 0.0089 | 0.0319 | 0.0727 | 0.1248 | 0.1040 | 0.1262 | 0.5255 | 9 | 12 | 22 | 46 | 73 | 101 | 133 | 177 | 238 | 0.0261 | 11.79 | 5.435 | 0.4724 | 19482.1 | 5010000 | 1530000000 | 533000000000 | 0.4602 | 0.1900 | 0.0169 | 0.0009 | 0.0928 | 0.0052 | 0.1893 | 0.0424 | 0.1626 | 0.0894 | 0.1630 | 0.1492 | 0.1587 | 0.1861 | 0.0954 | 0.1402 | 0.0745 | 0.1464 | 0.0468 | 0.2402 | 0.0006 | 0.0001 | 0.0007 | 0.0006 | 0.0017 | 0.0015 | 0.0093 | 0.0072 | 0.0425 | 0.0340 | 0.0820 | 0.0612 | 0.0679 | 0.0521 | 0.0976 | 0.0811 | 0.6977 | 0.7621 | 0.0009 | 0.0007 | 0.0013 | 0.0023 | 0.0028 | 0.0042 | 0.0180 | 0.0214 | 0.0688 | 0.0820 | 0.1143 | 0.1324 | 0.0930 | 0.0958 | 0.1199 | 0.1291 | 0.5810 | 0.5321 | 0.0007 | 0.0011 | 0.0034 | 0.0138 | 0.0527 | 0.0963 | 0.0820 | 0.1141 | 0.6359 | ||
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1049 | 621 | | 590 | 4448 | 85.8 | 21.32 | 144.11 | 133.60 | 56 | 64 | 73 | 81 | 87 | 93 | 99 | 106 | 114 | 0.1034 | 460 | 0.497 | 89.47 | 17.12 | 2 | 0.4254 | 251 | 0.0059 | 8.91 | 5.340 | 0.3127 | 7819.9 | 748619 | 74600000 | 7680000000 | 0.5406 | 0.1228 | 0.0066 | 0.0000 | 0.0197 | 0.0037 | 0.0656 | 0.0019 | 0.1016 | 0.0335 | 0.1311 | 0.0764 | 0.2557 | 0.1676 | 0.1213 | 0.0950 | 0.1279 | 0.1639 | 0.1705 | 0.4581 | 0.0000 | 0.0000 | 0.0023 | 0.0018 | 0.0023 | 0.0018 | 0.0227 | 0.0161 | 0.0975 | 0.0698 | 0.2245 | 0.1592 | 0.0998 | 0.0823 | 0.1678 | 0.1485 | 0.3832 | 0.5206 | 0.0000 | 0.0000 | 0.0074 | 0.0909 | 0.0662 | 0.1818 | 0.1103 | 0.2273 | 0.1838 | 0.3636 | 0.2721 | 0.0455 | 0.1176 | 0.0909 | 0.0809 | 0.0000 | 0.1618 | 0.0000 | 0.0032 | 0.0130 | 0.0260 | 0.0747 | 0.1494 | 0.1851 | 0.1071 | 0.1558 | 0.2857 | 25 | 39 | 55 | 74 | 98 | 130 | 170 | 228 | 340 | 0.0100 | 16.93 | 5.669 | 0.4305 | 38612.5 | 14500000 | 6620000000 | 3390000000000 | 0.5378 | 0.1265 | 0.0156 | 0.0023 | 0.0845 | 0.0068 | 0.1831 | 0.0288 | 0.1815 | 0.0788 | 0.1800 | 0.1455 | 0.1315 | 0.1856 | 0.0767 | 0.1667 | 0.0610 | 0.1439 | 0.0861 | 0.2417 | 0.0010 | 0.0013 | 0.0036 | 0.0025 | 0.0051 | 0.0033 | 0.0159 | 0.0134 | 0.0568 | 0.0473 | 0.0967 | 0.0854 | 0.0747 | 0.0703 | 0.0988 | 0.1000 | 0.6474 | 0.6766 | 0.0000 | 0.0037 | 0.0038 | 0.0019 | 0.0198 | 0.0131 | 0.0243 | 0.0411 | 0.0654 | 0.0626 | 0.1209 | 0.1280 | 0.0928 | 0.0888 | 0.1042 | 0.1271 | 0.5688 | 0.5336 | 0.0006 | 0.0000 | 0.0112 | 0.0262 | 0.0611 | 0.1185 | 0.0855 | 0.1017 | 0.5951 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 382 | 919 | | 6897 | 11121 | 362.8 | 74.41 | 225.10 | 252.79 | 267 | 298 | 321 | 341 | 358 | 379 | 401 | 427 | 462 | 0.0739 | 822 | 1.086 | 120.93 | 34.41 | 1 | 0.0406 | 280 | 0.0009 | 36.87 | 7.251 | 0.1983 | 137149.0 | 53900000 | 21900000000 | 9220000000000 | 0.4314 | 0.2131 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0005 | 0.0135 | 0.0012 | 0.0506 | 0.0134 | 0.0981 | 0.0302 | 0.1155 | 0.0258 | 0.1361 | 0.0368 | 0.5832 | 0.8921 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0004 | 0.0061 | 0.0010 | 0.0215 | 0.0104 | 0.0426 | 0.0219 | 0.0481 | 0.0148 | 0.0570 | 0.0214 | 0.8240 | 0.9300 | 0.0050 | 0.0000 | 0.0075 | 0.0000 | 0.0199 | 0.0000 | 0.0489 | 0.0000 | 0.1095 | 0.0000 | 0.1376 | 0.0000 | 0.1086 | 0.0000 | 0.1327 | 0.0000 | 0.4303 | 0.0000 | 0.0003 | 0.0024 | 0.0055 | 0.0240 | 0.0518 | 0.1046 | 0.0888 | 0.1001 | 0.6225 | 16 | 19 | 26 | 60 | 133 | 209 | 292 | 408 | 608 | 0.0252 | 45.18 | 5.945 | 0.4029 | 114568.0 | 77900000 | 62700000000 | 56900000000000 | 0.5295 | 0.1405 | 0.0233 | 0.0008 | 0.1395 | 0.0101 | 0.2197 | 0.0563 | 0.1828 | 0.1049 | 0.1612 | 0.1734 | 0.1275 | 0.1937 | 0.0762 | 0.1418 | 0.0489 | 0.1329 | 0.0209 | 0.1860 | 0.0004 | 0.0002 | 0.0004 | 0.0004 | 0.0021 | 0.0016 | 0.0092 | 0.0085 | 0.0536 | 0.0397 | 0.0929 | 0.0707 | 0.0709 | 0.0541 | 0.1009 | 0.0724 | 0.6695 | 0.7524 | 0.0003 | 0.0010 | 0.0008 | 0.0029 | 0.0058 | 0.0059 | 0.0202 | 0.0280 | 0.0810 | 0.0982 | 0.1221 | 0.1321 | 0.0928 | 0.0956 | 0.1260 | 0.1337 | 0.5510 | 0.5026 | 0.0000 | 0.0010 | 0.0036 | 0.0157 | 0.0703 | 0.1098 | 0.0834 | 0.1150 | 0.6013 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 402 | 281 | | 5163 | 11094 | 132.9 | 31.75 | 204.40 | 192.72 | 98 | 107 | 114 | 120 | 127 | 135 | 144 | 156 | 174 | 0.0753 | 835 | 1.001 | 90.14 | 24.74 | 1 | 0.0424 | 219 | 0.0024 | 20.29 | 6.351 | 0.2592 | 18683.1 | 2790000 | 443000000 | 75300000000 | 0.4578 | 0.1909 | 0.0003 | 0.0000 | 0.0025 | 0.0000 | 0.0034 | 0.0002 | 0.0224 | 0.0012 | 0.0771 | 0.0208 | 0.1572 | 0.0445 | 0.1683 | 0.0420 | 0.1981 | 0.0794 | 0.3707 | 0.8120 | 0.0002 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0091 | 0.0000 | 0.0343 | 0.0121 | 0.0698 | 0.0263 | 0.0770 | 0.0152 | 0.1062 | 0.0349 | 0.6996 | 0.9115 | 0.0044 | 0.0126 | 0.0142 | 0.0158 | 0.0230 | 0.0536 | 0.0678 | 0.1073 | 0.1497 | 0.1956 | 0.1913 | 0.1546 | 0.1049 | 0.1577 | 0.1355 | 0.1325 | 0.3093 | 0.1703 | 0.0031 | 0.0040 | 0.0108 | 0.0333 | 0.0787 | 0.1393 | 0.1016 | 0.1326 | 0.4966 | 20 | 34 | 61 | 100 | 147 | 198 | 262 | 353 | 492 | 0.0054 | 71.93 | 6.900 | 0.2998 | 78916.5 | 40300000 | 24100000000 | 16000000000000 | 0.4531 | 0.1995 | 0.0210 | 0.0003 | 0.1004 | 0.0108 | 0.2033 | 0.0378 | 0.1881 | 0.0917 | 0.1512 | 0.1677 | 0.1595 | 0.2108 | 0.0921 | 0.1540 | 0.0508 | 0.1423 | 0.0337 | 0.1847 | 0.0004 | 0.0002 | 0.0012 | 0.0020 | 0.0031 | 0.0030 | 0.0172 | 0.0109 | 0.0545 | 0.0442 | 0.0980 | 0.0771 | 0.0764 | 0.0584 | 0.1021 | 0.0867 | 0.6471 | 0.7176 | 0.0011 | 0.0020 | 0.0011 | 0.0023 | 0.0078 | 0.0106 | 0.0300 | 0.0381 | 0.0728 | 0.0866 | 0.1296 | 0.1333 | 0.0923 | 0.0899 | 0.1143 | 0.1148 | 0.5510 | 0.5224 | 0.0007 | 0.0014 | 0.0067 | 0.0219 | 0.0631 | 0.1112 | 0.0841 | 0.1170 | 0.5940 |