High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
SK-BR-3
0
DRAQ5 1 TMRE 2 2 2 1 927 522 image if available 3614 6289 297.5 144.28 59.44 77.60 127 157 192 233 266 305 406 465 511 0.1040 654 1.229 109.25 47.52 2 0.0819 296 0.0028 6.07 6.131 0.4083 109347.0
45800000
20700000000
9820000000000
0.3640 0.2549 0.0012 0.0000 0.0012 0.0006 0.0036 0.0025 0.0324 0.0086 0.1032 0.0531 0.1429 0.0834 0.1273 0.0562 0.1020 0.0828 0.4862 0.7128 0.0005 0.0000 0.0005 0.0004 0.0005 0.0015 0.0076 0.0030 0.0219 0.0203 0.0343 0.0263 0.0281 0.0192 0.0357 0.0312 0.8710 0.8980 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0016 0.0039 0.0331 0.0347 0.0410 0.0597 0.0316 0.0414 0.0458 0.0462 0.8469 0.8141 0.0020 0.0013 0.0027 0.0054 0.0229 0.0404 0.0242 0.0310 0.8700 8 11 14 19 26 38 58 92 162 0.0962 2.42 3.459 0.6933 9553.8
2410000
755000000
271000000000
0.5400 0.1318 0.0018 0.0033 0.0126 0.0122 0.0650 0.0236 0.1733 0.0447 0.2365 0.0943 0.2166 0.1561 0.1480 0.1423 0.1137 0.1740 0.0325 0.3496 0.0000 0.0015 0.0005 0.0034 0.0032 0.0076 0.0142 0.0125 0.0500 0.0386 0.0866 0.0773 0.0596 0.0583 0.0830 0.0735 0.7030 0.7273 0.0000 0.0000 0.0012 0.0014 0.0037 0.0064 0.0197 0.0227 0.0614 0.0716 0.1020 0.1106 0.0694 0.0738 0.0860 0.0865 0.6566 0.6270 0.0011 0.0027 0.0043 0.0160 0.0543 0.1005 0.0660 0.0787 0.6766
MCF 10A Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 819 837 image if available 4077 7402 164.0 45.49 281.51 208.60 106 126 139 150 161 172 185 201 225 0.0809 599 0.666 68.59 22.56 2 0.0518 211 0.0013 30.19 6.879 0.2104 28976.0
5470000
1100000000
232000000000
0.4785 0.1795 0.0028 0.0000 0.0032 0.0006 0.0065 0.0020 0.0341 0.0061 0.1138 0.0314 0.1876 0.0802 0.1618 0.0709 0.1834 0.0994 0.3069 0.7095 0.0006 0.0000 0.0010 0.0003 0.0019 0.0005 0.0081 0.0026 0.0430 0.0195 0.0783 0.0445 0.0608 0.0306 0.0935 0.0458 0.7126 0.8562 0.0043 0.0113 0.0185 0.0226 0.0120 0.0452 0.0663 0.1271 0.1261 0.1582 0.1815 0.2345 0.1239 0.1356 0.1424 0.0989 0.3250 0.1667 0.0015 0.0021 0.0072 0.0355 0.0762 0.1340 0.1061 0.1175 0.5198 41 86 136 190 247 308 370 448 564 0.0018 128.90 7.431 0.1991 122752.0
67400000
43400000000
31600000000000
0.5494 0.1250 0.0218 0.0004 0.1102 0.0047 0.2408 0.0505 0.1748 0.0920 0.1769 0.1749 0.1363 0.2080 0.0798 0.1531 0.0428 0.1385 0.0167 0.1778 0.0000 0.0000 0.0010 0.0000 0.0035 0.0011 0.0151 0.0089 0.0627 0.0498 0.1204 0.0924 0.0929 0.0759 0.1327 0.1043 0.5715 0.6676 0.0000 0.0020 0.0042 0.0036 0.0096 0.0137 0.0301 0.0493 0.1131 0.1301 0.1521 0.1876 0.1212 0.1256 0.1613 0.1520 0.4083 0.3360 0.0015 0.0024 0.0049 0.0182 0.0809 0.1469 0.1031 0.1338 0.5082
MDA-MB-231 A443654
0.12
uM
DRAQ5 1 TMRE 2 2 11 1 421 124 image if available 5496 10543 841.5 127.28 116.18 190.68 650 752 803 837 864 891 918 946 983 0.0719 758 0.901 57.38 16.12 1 0.0260 143 0.0008 45.33 7.373 0.1837 724381.0
635000000
565000000000
510000000000000
0.4046 0.2403 0.0000 0.0000 0.0002 0.0002 0.0004 0.0000 0.0037 0.0006 0.0217 0.0126 0.0354 0.0196 0.0394 0.0116 0.0630 0.0199 0.8361 0.9356 0.0000 0.0000 0.0000 0.0002 0.0000 0.0000 0.0019 0.0006 0.0126 0.0126 0.0229 0.0196 0.0169 0.0116 0.0272 0.0199 0.9185 0.9356 0.0145 0.0000 0.0364 0.0000 0.0545 0.0000 0.1200 0.0000 0.1200 0.0000 0.1418 0.0000 0.1455 0.0000 0.1091 0.0000 0.2582 0.0000 0.0016 0.0038 0.0047 0.0144 0.0357 0.0510 0.0620 0.0780 0.7489 11 14 18 24 31 47 83 165 375 0.1122 20.14 4.053 0.6479 49852.9
32900000
26200000000
23500000000000
0.4577 0.2035 0.0423 0.0022 0.1482 0.0186 0.2052 0.1010 0.1580 0.1256 0.1612 0.1330 0.1075 0.1627 0.0749 0.1085 0.0619 0.1226 0.0407 0.2259 0.0007 0.0006 0.0007 0.0012 0.0071 0.0066 0.0172 0.0124 0.0487 0.0469 0.0774 0.0650 0.0551 0.0478 0.0804 0.0728 0.7127 0.7468 0.0000 0.0005 0.0004 0.0014 0.0030 0.0038 0.0179 0.0141 0.0640 0.0756 0.0989 0.1136 0.0648 0.0700 0.0942 0.1103 0.6567 0.6108 0.0000 0.0027 0.0027 0.0170 0.0572 0.0877 0.0634 0.0912 0.6781
MCF 10A Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 993 394 image if available 3513 2040 83.9 23.57 182.26 150.78 58 64 69 74 80 86 93 102 117 0.2098 428 0.610 126.40 36.89 1 0.1153 405 0.0023 17.58 6.355 0.2696 7588.6
740923
77800000
8750000000
0.4603 0.1930 0.0011 0.0000 0.0056 0.0007 0.0134 0.0026 0.0431 0.0082 0.0968 0.0264 0.1556 0.0541 0.1617 0.0463 0.1796 0.0825 0.3430 0.7792 0.0008 0.0000 0.0012 0.0003 0.0047 0.0003 0.0176 0.0029 0.0434 0.0159 0.0672 0.0308 0.0649 0.0238 0.0883 0.0443 0.7120 0.8816 0.0000 0.0059 0.0052 0.0059 0.0181 0.0265 0.0557 0.0649 0.0959 0.1150 0.1386 0.1593 0.1010 0.1062 0.1451 0.1386 0.4404 0.3776 0.0000 0.0059 0.0092 0.0301 0.0682 0.1009 0.0904 0.1193 0.5760 38 61 78 94 117 169 238 312 410 0.0064 25.03 5.822 0.3730 55941.1
22700000
10800000000
5710000000000
0.5146 0.1363 0.0251 0.0117 0.1967 0.0156 0.1799 0.0702 0.1674 0.1384 0.1632 0.2242 0.1297 0.1696 0.0795 0.1345 0.0418 0.1228 0.0167 0.1131 0.0011 0.0037 0.0055 0.0037 0.0033 0.0065 0.0199 0.0140 0.0719 0.0699 0.1062 0.0885 0.0752 0.0690 0.1195 0.1053 0.5973 0.6393 0.0000 0.0000 0.0015 0.0036 0.0075 0.0054 0.0256 0.0536 0.0902 0.1161 0.1504 0.1393 0.1158 0.1339 0.1504 0.1750 0.4586 0.3732 0.0000 0.0013 0.0051 0.0269 0.0654 0.1333 0.0885 0.1321 0.5474
MDA-MB-231 Barasertib
0.12
uM
DRAQ5 1 TMRE 2 2 15 1 372 900 image if available 5044 9324 570.5 98.09 110.30 193.81 423 504 548 574 591 608 625 644 675 0.0741 691 0.949 144.16 41.87 3 0.0765 386 0.0009 58.08 7.313 0.1858 335121.0
201000000
123000000000
76200000000000
0.4530 0.1918 0.0003 0.0000 0.0008 0.0000 0.0015 0.0002 0.0055 0.0012 0.0271 0.0139 0.0472 0.0212 0.0462 0.0133 0.0650 0.0234 0.8066 0.9268 0.0000 0.0000 0.0000 0.0000 0.0002 0.0002 0.0018 0.0012 0.0148 0.0139 0.0237 0.0212 0.0189 0.0133 0.0283 0.0218 0.9121 0.9285 0.0051 1.0000 0.0204 0.0000 0.0382 0.0000 0.0789 0.0000 0.1399 0.0000 0.1527 0.0000 0.1425 0.0000 0.1552 0.0000 0.2672 0.0000 0.0006 0.0016 0.0039 0.0132 0.0319 0.0631 0.0673 0.0879 0.7304 13 15 17 20 24 37 65 143 347 0.2499 4.68 3.068 0.7533 49725.0
35000000
30000000000
29200000000000
0.6863 0.0611 0.0201 0.0070 0.0828 0.0120 0.2081 0.0468 0.1834 0.0807 0.1969 0.1723 0.1454 0.1912 0.0805 0.1524 0.0403 0.1404 0.0425 0.1972 0.0004 0.0022 0.0004 0.0022 0.0021 0.0065 0.0116 0.0151 0.0418 0.0391 0.0708 0.0613 0.0472 0.0459 0.0911 0.0911 0.7345 0.7368 0.0000 0.0006 0.0005 0.0006 0.0051 0.0011 0.0142 0.0146 0.0524 0.0611 0.0956 0.0952 0.0478 0.0538 0.0935 0.0947 0.6909 0.6784 0.0000 0.0000 0.0019 0.0116 0.0551 0.0811 0.0487 0.0982 0.7034
MCF7 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 844 729 image if available 5195 6746 513.2 118.34 131.41 201.76 374 422 455 484 509 533 559 598 663 0.1269 856 1.179 136.50 52.00 4 0.0670 348 0.0006 81.67 7.590 0.1403 277409.0
157000000
93300000000
57800000000000
0.4641 0.1828 0.0000 0.0000 0.0000 0.0000 0.0092 0.0002 0.0187 0.0015 0.0728 0.0317 0.1260 0.0589 0.1091 0.0502 0.1534 0.0757 0.5108 0.7819 0.0000 0.0000 0.0000 0.0000 0.0012 0.0000 0.0037 0.0008 0.0387 0.0254 0.0701 0.0404 0.0576 0.0258 0.0831 0.0416 0.7456 0.8661 0.0059 0.0100 0.0118 0.0134 0.0178 0.0334 0.0675 0.1104 0.1349 0.1371 0.1527 0.1605 0.0982 0.1171 0.1396 0.1371 0.3716 0.2809 0.0012 0.0020 0.0083 0.0313 0.0944 0.1583 0.1035 0.1432 0.4578 7 9 11 15 30 63 128 229 416 0.1248 27.25 4.487 0.5729 57968.2
37400000
29800000000
27700000000000
0.6421 0.0717 0.0374 0.0045 0.1828 0.0269 0.3106 0.1256 0.1806 0.1469 0.1564 0.2096 0.0639 0.2096 0.0419 0.1188 0.0176 0.0953 0.0088 0.0628 0.0000 0.0004 0.0004 0.0024 0.0009 0.0028 0.0121 0.0108 0.0689 0.0667 0.1123 0.0895 0.0671 0.0667 0.0988 0.0927 0.6395 0.6681 0.0000 0.0000 0.0011 0.0000 0.0028 0.0050 0.0213 0.0292 0.0786 0.0856 0.1296 0.1290 0.0836 0.0862 0.1072 0.1141 0.5758 0.5509 0.0000 0.0010 0.0035 0.0180 0.0721 0.1181 0.0756 0.1086 0.6031
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1120 374 image if available 1013 7639 932.9 280.82 18.77 68.99 520 632 745 866 972 1068 1154 1217 1274 0.0730 558 0.951 63.01 16.64 2 0.1382 140 0.0016 66.58 6.568 0.1620 949022.0
1030000000
1160000000000
1.34E+15
0.2997 0.3332 0.0000 0.0000 0.0000 0.0000 0.0028 0.0013 0.0141 0.0025 0.1155 0.0401 0.2197 0.0877 0.1380 0.0401 0.1662 0.0677 0.3437 0.7607 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0042 0.0000 0.0368 0.0311 0.0637 0.0681 0.0326 0.0219 0.0425 0.0381 0.8201 0.8408 0.0000 0.0000 0.0000 0.0145 0.0000 0.0000 0.0171 0.0580 0.0484 0.1449 0.0883 0.1014 0.0570 0.1014 0.0712 0.2029 0.7179 0.3768 0.0000 0.0000 0.0000 0.0000 0.0427 0.0816 0.0278 0.0594 0.7885 4 5 6 6 8 8 9 11 13 0.1323 2.99 1.460 0.4553 5111.7
3110000
2280000000
1870000000000
0.4103 0.1711 0.2687 0.1623 0.2463 0.1455 0.2015 0.1545 0.2612 0.1636 0.0224 0.1325 0.0000 0.1273 0.0000 0.0688 0.0000 0.0416 0.0000 0.0039 0.0357 0.1050 0.0187 0.0915 0.0221 0.0882 0.0306 0.0747 0.0629 0.0571 0.0510 0.0756 0.0952 0.0655 0.0799 0.0756 0.6037 0.3669 0.0000 0.0000 0.0022 0.0000 0.0066 0.0000 0.0176 0.0143 0.0683 0.0903 0.1101 0.1021 0.0551 0.0570 0.0991 0.1069 0.6410 0.6295 0.0100 0.0060 0.0040 0.0260 0.0680 0.0820 0.0740 0.0900 0.6400
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 785 881 image if available 3192 11680 293.5 228.83 175.43 253.66 121 132 141 152 168 234 343 454 665 0.0779 910 0.548 96.01 23.41 1 0.0883 282 0.0123 12.19 5.534 0.4708 138508.0
89800000
68800000000
57800000000000
0.3485 0.2740 0.0000 0.0026 0.0088 0.0040 0.0234 0.0026 0.0848 0.0145 0.2193 0.0818 0.2339 0.1385 0.0994 0.0989 0.1053 0.1280 0.2251 0.5290 0.0000 0.0013 0.0000 0.0020 0.0000 0.0013 0.0039 0.0040 0.0308 0.0246 0.0394 0.0378 0.0308 0.0252 0.0450 0.0358 0.8502 0.8680 0.0011 0.0000 0.0000 0.0000 0.0022 0.0013 0.0043 0.0053 0.0335 0.0427 0.0475 0.0521 0.0367 0.0427 0.0583 0.0681 0.8164 0.7877 0.0000 0.0000 0.0000 0.0046 0.0316 0.0418 0.0316 0.0501 0.8403 8 11 13 16 30 86 182 350 586 0.1317 8.32 4.290 0.5950 95114.7
66900000
53100000000
45800000000000
0.4601 0.1966 0.0174 0.0027 0.1172 0.0096 0.2084 0.0541 0.1852 0.1021 0.1881 0.1568 0.1389 0.1637 0.0767 0.1301 0.0449 0.1548 0.0232 0.2260 0.0003 0.0000 0.0003 0.0005 0.0025 0.0018 0.0104 0.0100 0.0440 0.0382 0.0552 0.0567 0.0575 0.0473 0.0699 0.0678 0.7600 0.7777 0.0000 0.0007 0.0022 0.0027 0.0040 0.0065 0.0160 0.0143 0.0413 0.0419 0.0703 0.0671 0.0518 0.0504 0.0679 0.0740 0.7465 0.7423 0.0000 0.0020 0.0031 0.0134 0.0431 0.0641 0.0532 0.0661 0.7549
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 434 702 image if available 366 1008 101.8 15.33 117.32 181.93 80 86 92 98 103 108 111 115 124 0.2123 214 1.232 111.40 47.13 1 0.7978 292 0.0164 2.19 4.307 0.5322 10587.6
1130000
122000000
13400000000
0.3074 0.3364 0.0000 0.0000 0.0035 0.0000 0.0000 0.0000 0.0211 0.0055 0.0526 0.0437 0.1719 0.1202 0.0842 0.0328 0.0982 0.0437 0.5684 0.7541 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0123 0.0055 0.0401 0.0437 0.1204 0.1202 0.0432 0.0328 0.0401 0.0437 0.7438 0.7541 0.0000 0.0000 0.0256 0.0000 0.0256 0.0000 0.1026 0.0000 0.1026 0.0000 0.2051 0.0000 0.1026 0.0000 0.2308 0.0000 0.2051 0.0000 0.0000 0.0000 0.0158 0.0263 0.0526 0.1316 0.0842 0.0947 0.5947 11 13 15 21 33 58 109 190 334 0.1012 55.96 4.139 0.5623 46830.7
29000000
21700000000
18100000000000
0.4240 0.1879 0.1642 0.0070 0.2537 0.0986 0.1642 0.1690 0.1493 0.1408 0.1194 0.1408 0.0896 0.1620 0.0448 0.1056 0.0149 0.0986 0.0000 0.0775 0.0000 0.0000 0.0000 0.0000 0.0061 0.0027 0.0457 0.0348 0.0793 0.0668 0.1250 0.1364 0.0854 0.0668 0.1494 0.1337 0.5091 0.5588 0.0000 0.0043 0.0038 0.0086 0.0268 0.0172 0.0345 0.0302 0.1188 0.1207 0.1341 0.1466 0.0996 0.1034 0.1533 0.1767 0.4291 0.3922 0.0000 0.0035 0.0177 0.0389 0.0989 0.1272 0.1095 0.1484 0.4558
MDA-MB-231 A443654
1.1
uM
DRAQ5 1 TMRE 2 1 12 1 708 397 image if available 15447 27394 562.4 113.78 118.30 212.73 394 458 507 542 576 606 636 667 703 0.0495 1356 0.896 108.19 30.00 3 0.0188 291 0.0006 29.72 7.605 0.2191 329218.0
199000000
124000000000
78600000000000
0.3988 0.2308 0.0014 0.0000 0.0019 0.0001 0.0040 0.0004 0.0105 0.0011 0.0269 0.0087 0.0473 0.0169 0.0485 0.0102 0.0672 0.0157 0.7922 0.9469 0.0001 0.0000 0.0002 0.0000 0.0005 0.0001 0.0023 0.0010 0.0107 0.0080 0.0188 0.0166 0.0160 0.0091 0.0204 0.0143 0.9310 0.9510 0.0029 0.0000 0.0095 0.0179 0.0147 0.0536 0.0297 0.1607 0.0612 0.1250 0.0718 0.1071 0.0872 0.2500 0.1213 0.1071 0.6015 0.1786 0.0008 0.0010 0.0032 0.0069 0.0226 0.0401 0.0411 0.0534 0.8309 7 9 10 11 12 15 40 206 467 0.3132 20.18 3.462 0.7115 59247.2
38200000
27600000000
21600000000000
0.5023 0.1444 0.0436 0.0036 0.1336 0.0128 0.2377 0.1026 0.1744 0.1354 0.1547 0.1810 0.1069 0.1882 0.0675 0.1055 0.0520 0.1119 0.0295 0.1589 0.0000 0.0003 0.0003 0.0004 0.0010 0.0004 0.0058 0.0038 0.0203 0.0189 0.0418 0.0353 0.0301 0.0220 0.0517 0.0418 0.8491 0.8771 0.0000 0.0000 0.0006 0.0005 0.0003 0.0005 0.0058 0.0079 0.0263 0.0302 0.0558 0.0631 0.0452 0.0492 0.0622 0.0705 0.8037 0.7782 0.0000 0.0000 0.0006 0.0049 0.0263 0.0486 0.0405 0.0571 0.8221
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 209 570 image if available 4703 11257 455.0 77.10 137.18 277.92 340 398 427 444 459 475 493 516 549 0.0636 716 0.833 89.36 25.02 3 0.0515 242 0.0019 16.09 6.616 0.2886 212933.0
102000000
50100000000
25100000000000
0.4498 0.1891 0.0000 0.0000 0.0006 0.0000 0.0011 0.0002 0.0053 0.0006 0.0283 0.0153 0.0415 0.0267 0.0404 0.0162 0.0569 0.0265 0.8258 0.9144 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0022 0.0006 0.0175 0.0150 0.0253 0.0249 0.0212 0.0146 0.0305 0.0226 0.9033 0.9222 0.0040 0.0000 0.0120 0.1429 0.0080 0.2143 0.0300 0.1429 0.0580 0.2857 0.0920 0.1429 0.0820 0.0714 0.0900 0.0000 0.6240 0.0000 0.0032 0.0069 0.0105 0.0242 0.0395 0.0492 0.0629 0.0786 0.7251 9 11 13 15 18 27 60 180 452 0.1894 29.54 3.820 0.6610 96051.8
107000000
152000000000
257000000000000
0.3706 0.2754 0.0734 0.0034 0.1353 0.0339 0.2638 0.1141 0.1789 0.1548 0.1628 0.1390 0.0757 0.1921 0.0436 0.1209 0.0367 0.1028 0.0298 0.1390 0.0004 0.0000 0.0007 0.0010 0.0032 0.0010 0.0140 0.0094 0.0415 0.0439 0.0727 0.0638 0.0466 0.0449 0.0659 0.0651 0.7550 0.7708 0.0000 0.0000 0.0034 0.0014 0.0038 0.0027 0.0089 0.0119 0.0539 0.0562 0.0883 0.0965 0.0526 0.0562 0.0870 0.0942 0.7020 0.6808 0.0004 0.0012 0.0019 0.0105 0.0487 0.0790 0.0487 0.0821 0.7275
MDA-MB-231 Barasertib
10
uM
DRAQ5 1 TMRE 2 1 15 1 900 171 image if available 3930 11298 497.7 103.96 94.40 173.19 316 409 476 500 521 540 560 583 613 0.0641 724 0.847 112.54 33.02 4 0.0832 327 0.0011 32.58 7.096 0.2211 258499.0
139000000
76000000000
42400000000000
0.3874 0.2511 0.0008 0.0003 0.0015 0.0000 0.0057 0.0000 0.0069 0.0008 0.0413 0.0186 0.0462 0.0251 0.0569 0.0178 0.0810 0.0276 0.7597 0.9099 0.0000 0.0003 0.0000 0.0000 0.0000 0.0000 0.0003 0.0008 0.0197 0.0186 0.0188 0.0251 0.0172 0.0178 0.0260 0.0276 0.9179 0.9099 0.0052 0.0000 0.0140 0.0000 0.0315 0.0000 0.0542 0.0000 0.0717 0.0000 0.0944 0.0000 0.1119 0.0000 0.1556 0.0000 0.4615 0.0000 0.0012 0.0042 0.0037 0.0108 0.0279 0.0396 0.0500 0.0629 0.7997 6 7 9 10 14 24 52 125 339 0.1266 21.37 4.235 0.6154 38902.8
22700000
15400000000
11500000000000
0.5106 0.1373 0.0416 0.0018 0.1323 0.0210 0.2420 0.0602 0.1739 0.1267 0.1815 0.2124 0.1361 0.2042 0.0586 0.1258 0.0265 0.1167 0.0076 0.1313 0.0000 0.0003 0.0003 0.0009 0.0031 0.0015 0.0097 0.0106 0.0497 0.0439 0.0660 0.0569 0.0453 0.0375 0.0729 0.0623 0.7530 0.7860 0.0000 0.0000 0.0008 0.0000 0.0013 0.0018 0.0139 0.0172 0.0499 0.0548 0.0820 0.0743 0.0465 0.0535 0.0714 0.0729 0.7342 0.7254 0.0008 0.0000 0.0015 0.0131 0.0528 0.0670 0.0466 0.0751 0.7432
MDA-MB-231 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 350 768 image if available 2148 7377 649.8 190.42 59.61 108.11 361 467 544 624 689 729 767 811 863 0.0729 538 0.439 61.06 9.22 3 0.0791 170 0.0009 72.75 7.161 0.1651 458473.0
344000000
270000000000
221000000000000
0.4160 0.2058 0.0000 0.0000 0.0000 0.0000 0.0050 0.0006 0.0291 0.0023 0.0824 0.0283 0.1568 0.0702 0.1075 0.0385 0.1397 0.0645 0.4794 0.7957 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0045 0.0016 0.0293 0.0240 0.0560 0.0464 0.0350 0.0235 0.0592 0.0427 0.8160 0.8617 0.0000 0.0094 0.0000 0.0283 0.0035 0.0189 0.0260 0.0566 0.0781 0.1415 0.1163 0.2264 0.0885 0.0472 0.1250 0.1038 0.5625 0.3679 0.0000 0.0000 0.0000 0.0091 0.0432 0.0639 0.0490 0.0763 0.7585 7 9 11 13 16 21 32 64 203 0.0746 10.49 3.983 0.6307 15239.4
6560000
3660000000
2420000000000
0.2920 0.3302 0.0000 0.0050 0.0655 0.0113 0.2143 0.0239 0.2292 0.0642 0.2054 0.1597 0.1429 0.2013 0.0774 0.1660 0.0506 0.1698 0.0149 0.1987 0.0000 0.0019 0.0017 0.0043 0.0040 0.0038 0.0115 0.0125 0.0340 0.0355 0.0530 0.0485 0.0363 0.0384 0.0594 0.0677 0.8000 0.7872 0.0000 0.0000 0.0000 0.0000 0.0043 0.0031 0.0129 0.0109 0.0372 0.0427 0.0558 0.0637 0.0393 0.0365 0.0629 0.0637 0.7877 0.7793 0.0000 0.0000 0.0007 0.0170 0.0352 0.0483 0.0463 0.0614 0.7911
BT-20
0
DRAQ5 1 TMRE 2 2 2 1 564 834 image if available 5735 9264 386.5 90.39 113.25 134.91 287 312 332 351 371 393 423 457 512 0.0955 885 1.153 94.87 36.50 1 0.0424 243 0.0010 39.47 7.169 0.1888 157556.0
67800000
30700000000
14700000000000
0.4429 0.2115 0.0008 0.0000 0.0019 0.0006 0.0036 0.0017 0.0202 0.0044 0.0679 0.0189 0.1422 0.0466 0.1486 0.0405 0.1705 0.0615 0.4443 0.8259 0.0004 0.0000 0.0011 0.0002 0.0024 0.0009 0.0105 0.0021 0.0358 0.0126 0.0710 0.0308 0.0693 0.0219 0.0813 0.0324 0.7282 0.8991 0.0076 0.0105 0.0123 0.0026 0.0123 0.0211 0.0550 0.0632 0.0920 0.1395 0.1404 0.1447 0.0920 0.1289 0.1262 0.1421 0.4620 0.3474 0.0012 0.0032 0.0097 0.0385 0.0838 0.1187 0.0956 0.1126 0.5367 9 11 13 22 52 96 147 211 309 0.0380 20.61 5.347 0.4709 31025.6
11600000
5240000000
2690000000000
0.6389 0.0617 0.0305 0.0023 0.1469 0.0170 0.2362 0.0978 0.1627 0.1213 0.1345 0.1582 0.0949 0.1687 0.0983 0.1201 0.0588 0.1125 0.0373 0.2021 0.0005 0.0000 0.0003 0.0002 0.0016 0.0026 0.0128 0.0086 0.0534 0.0432 0.0826 0.0776 0.0631 0.0491 0.1081 0.0918 0.6777 0.7269 0.0000 0.0008 0.0010 0.0008 0.0054 0.0051 0.0217 0.0249 0.0633 0.0785 0.1178 0.1224 0.0796 0.0890 0.1260 0.1383 0.5852 0.5404 0.0000 0.0006 0.0027 0.0183 0.0601 0.0914 0.0787 0.1213 0.6269