High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 703 | 330 | | 1517 | 7267 | 260.9 | 69.91 | 59.78 | 117.99 | 178 | 191 | 206 | 227 | 248 | 274 | 304 | 331 | 369 | 0.0860 | 625 | 1.115 | 107.79 | 38.05 | 1 | 0.1793 | 272 | 0.0105 | 1.72 | 4.763 | 0.5649 | 72953.0 | 21700000 | 6830000000 | 2240000000000 | 0.3508 | 0.2996 | 0.0016 | 0.0000 | 0.0031 | 0.0000 | 0.0062 | 0.0015 | 0.0171 | 0.0067 | 0.0715 | 0.0340 | 0.0964 | 0.0503 | 0.1026 | 0.0392 | 0.1291 | 0.0673 | 0.5723 | 0.8010 | 0.0010 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0040 | 0.0306 | 0.0224 | 0.0373 | 0.0369 | 0.0335 | 0.0257 | 0.0450 | 0.0383 | 0.8431 | 0.8727 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0061 | 0.0124 | 0.0549 | 0.0423 | 0.0610 | 0.0547 | 0.0549 | 0.0448 | 0.1220 | 0.0821 | 0.0854 | 0.7512 | 0.6159 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0337 | 0.0527 | 0.0366 | 0.0439 | 0.8228 | 7 | 8 | 9 | 10 | 11 | 15 | 28 | 57 | 188 | 0.1752 | 2.71 | 2.781 | 0.6871 | 17493.2 | 7830000 | 4090000000 | 2340000000000 | 0.4255 | 0.2007 | 0.0273 | 0.0043 | 0.0648 | 0.0086 | 0.1297 | 0.0114 | 0.2150 | 0.0643 | 0.2116 | 0.1186 | 0.1502 | 0.1686 | 0.1229 | 0.1429 | 0.0614 | 0.1629 | 0.0171 | 0.3186 | 0.0031 | 0.0010 | 0.0037 | 0.0021 | 0.0074 | 0.0026 | 0.0155 | 0.0129 | 0.0372 | 0.0290 | 0.0440 | 0.0403 | 0.0415 | 0.0445 | 0.0551 | 0.0672 | 0.7926 | 0.8004 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0023 | 0.0024 | 0.0053 | 0.0097 | 0.0371 | 0.0308 | 0.0393 | 0.0559 | 0.0446 | 0.0454 | 0.0598 | 0.0608 | 0.8086 | 0.7950 | 0.0000 | 0.0021 | 0.0049 | 0.0119 | 0.0295 | 0.0372 | 0.0400 | 0.0534 | 0.8209 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 580 | 433 | | 1493 | 7000 | 280.3 | 39.92 | 26.94 | 45.70 | 230 | 246 | 259 | 269 | 278 | 289 | 298 | 312 | 333 | 0.0730 | 511 | 0.722 | 72.57 | 16.03 | 1 | 0.1092 | 163 | 0.0044 | 8.62 | 5.687 | 0.3499 | 80150.8 | 23400000 | 6950000000 | 2110000000000 | 0.4223 | 0.2148 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0000 | 0.0000 | 0.0064 | 0.0007 | 0.0385 | 0.0235 | 0.0577 | 0.0450 | 0.0513 | 0.0215 | 0.0810 | 0.0403 | 0.7642 | 0.8690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0007 | 0.0246 | 0.0221 | 0.0377 | 0.0442 | 0.0261 | 0.0181 | 0.0399 | 0.0328 | 0.8681 | 0.8821 | 0.0226 | 0.2000 | 0.0150 | 0.2000 | 0.0526 | 0.4000 | 0.0677 | 0.2000 | 0.0602 | 0.0000 | 0.1053 | 0.0000 | 0.0902 | 0.0000 | 0.1278 | 0.0000 | 0.4586 | 0.0000 | 0.0014 | 0.0014 | 0.0069 | 0.0220 | 0.0495 | 0.0755 | 0.0975 | 0.1319 | 0.6140 | 7 | 8 | 9 | 10 | 12 | 15 | 20 | 33 | 57 | 0.2933 | 1.67 | 2.358 | 0.8342 | 2814.2 | 777978 | 343000000 | 188000000000 | 0.6091 | 0.1098 | 0.0437 | 0.0353 | 0.0542 | 0.0453 | 0.0822 | 0.0637 | 0.1014 | 0.0599 | 0.1294 | 0.0860 | 0.1451 | 0.1083 | 0.1521 | 0.1045 | 0.1573 | 0.1421 | 0.1346 | 0.3548 | 0.0065 | 0.0172 | 0.0101 | 0.0192 | 0.0081 | 0.0204 | 0.0141 | 0.0188 | 0.0252 | 0.0337 | 0.0348 | 0.0425 | 0.0403 | 0.0357 | 0.0685 | 0.0665 | 0.7924 | 0.7459 | 0.0035 | 0.0050 | 0.0042 | 0.0084 | 0.0099 | 0.0168 | 0.0156 | 0.0218 | 0.0453 | 0.0536 | 0.0545 | 0.0662 | 0.0630 | 0.0679 | 0.1288 | 0.1274 | 0.6752 | 0.6329 | 0.0024 | 0.0047 | 0.0082 | 0.0141 | 0.0294 | 0.0500 | 0.0488 | 0.1106 | 0.7318 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 389 | 150 | | 4606 | 15170 | 424.9 | 103.36 | 120.09 | 186.60 | 306 | 339 | 363 | 386 | 408 | 432 | 458 | 507 | 588 | 0.0560 | 850 | 1.111 | 95.13 | 27.89 | 1 | 0.0480 | 221 | 0.0012 | 30.61 | 6.994 | 0.2232 | 191216.0 | 91000000 | 45700000000 | 24100000000000 | 0.4331 | 0.2087 | 0.0004 | 0.0000 | 0.0014 | 0.0005 | 0.0043 | 0.0024 | 0.0159 | 0.0046 | 0.0524 | 0.0246 | 0.1229 | 0.0476 | 0.1175 | 0.0410 | 0.1431 | 0.0659 | 0.5421 | 0.8134 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0027 | 0.0002 | 0.0087 | 0.0013 | 0.0278 | 0.0148 | 0.0578 | 0.0278 | 0.0602 | 0.0168 | 0.0801 | 0.0354 | 0.7618 | 0.9036 | 0.0011 | 0.0118 | 0.0078 | 0.0024 | 0.0111 | 0.0118 | 0.0277 | 0.0729 | 0.0632 | 0.0965 | 0.1164 | 0.1412 | 0.0510 | 0.1529 | 0.0854 | 0.1506 | 0.6364 | 0.3600 | 0.0035 | 0.0025 | 0.0122 | 0.0294 | 0.0704 | 0.1160 | 0.0821 | 0.1013 | 0.5826 | 7 | 9 | 12 | 15 | 24 | 53 | 116 | 205 | 380 | 0.0719 | 21.43 | 4.823 | 0.5539 | 49238.9 | 29200000 | 20700000000 | 16600000000000 | 0.4072 | 0.2209 | 0.0112 | 0.0005 | 0.0637 | 0.0029 | 0.1751 | 0.0280 | 0.2032 | 0.0619 | 0.1751 | 0.1581 | 0.1526 | 0.2116 | 0.1058 | 0.1654 | 0.0702 | 0.1537 | 0.0431 | 0.2180 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0014 | 0.0014 | 0.0111 | 0.0059 | 0.0296 | 0.0273 | 0.0544 | 0.0427 | 0.0464 | 0.0368 | 0.0657 | 0.0505 | 0.7911 | 0.8351 | 0.0010 | 0.0008 | 0.0003 | 0.0006 | 0.0025 | 0.0025 | 0.0113 | 0.0139 | 0.0420 | 0.0541 | 0.0795 | 0.0889 | 0.0566 | 0.0606 | 0.0881 | 0.0878 | 0.7186 | 0.6907 | 0.0004 | 0.0020 | 0.0047 | 0.0105 | 0.0368 | 0.0616 | 0.0504 | 0.0780 | 0.7555 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 797 | 276 | | 3081 | 14857 | 257.1 | 73.60 | 95.99 | 124.19 | 175 | 187 | 202 | 218 | 241 | 266 | 296 | 325 | 367 | 0.0703 | 1045 | 0.709 | 60.54 | 16.03 | 2 | 0.0568 | 175 | 0.0097 | 3.01 | 5.047 | 0.5308 | 71538.3 | 21500000 | 6880000000 | 2330000000000 | 0.3683 | 0.2682 | 0.0023 | 0.0000 | 0.0053 | 0.0000 | 0.0107 | 0.0015 | 0.0328 | 0.0041 | 0.0710 | 0.0354 | 0.1154 | 0.0479 | 0.1054 | 0.0420 | 0.1398 | 0.0593 | 0.5172 | 0.8099 | 0.0014 | 0.0000 | 0.0019 | 0.0000 | 0.0043 | 0.0007 | 0.0125 | 0.0013 | 0.0288 | 0.0202 | 0.0389 | 0.0276 | 0.0408 | 0.0189 | 0.0504 | 0.0315 | 0.8209 | 0.8998 | 0.0013 | 0.0000 | 0.0000 | 0.0111 | 0.0090 | 0.0028 | 0.0168 | 0.0306 | 0.0530 | 0.0889 | 0.0917 | 0.1306 | 0.0646 | 0.1139 | 0.0904 | 0.1500 | 0.6731 | 0.4722 | 0.0015 | 0.0015 | 0.0052 | 0.0126 | 0.0238 | 0.0535 | 0.0416 | 0.0558 | 0.8045 | 12 | 19 | 29 | 42 | 54 | 70 | 95 | 135 | 230 | 0.0663 | 4.54 | 3.869 | 0.7237 | 24635.6 | 11400000 | 7270000000 | 5520000000000 | 0.4425 | 0.1810 | 0.0092 | 0.0039 | 0.0252 | 0.0102 | 0.0406 | 0.0158 | 0.0729 | 0.0304 | 0.1237 | 0.0621 | 0.1566 | 0.0900 | 0.1494 | 0.0954 | 0.1869 | 0.1280 | 0.2356 | 0.5641 | 0.0025 | 0.0017 | 0.0033 | 0.0049 | 0.0040 | 0.0052 | 0.0113 | 0.0100 | 0.0302 | 0.0240 | 0.0458 | 0.0344 | 0.0473 | 0.0408 | 0.0691 | 0.0611 | 0.7864 | 0.8179 | 0.0008 | 0.0007 | 0.0034 | 0.0027 | 0.0059 | 0.0050 | 0.0163 | 0.0174 | 0.0487 | 0.0557 | 0.0704 | 0.0795 | 0.0637 | 0.0651 | 0.0789 | 0.0849 | 0.7118 | 0.6890 | 0.0011 | 0.0052 | 0.0059 | 0.0142 | 0.0363 | 0.0542 | 0.0582 | 0.0716 | 0.7533 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 414 | 325 | | 5437 | 7882 | 437.9 | 83.20 | 101.98 | 125.88 | 341 | 366 | 387 | 407 | 426 | 445 | 470 | 508 | 561 | 0.1009 | 795 | 1.215 | 56.61 | 22.20 | 1 | 0.0270 | 147 | 0.0013 | 34.95 | 6.913 | 0.2030 | 198637.0 | 93400000 | 45500000000 | 22900000000000 | 0.4444 | 0.2029 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0008 | 0.0000 | 0.0120 | 0.0013 | 0.0499 | 0.0139 | 0.1259 | 0.0375 | 0.1288 | 0.0278 | 0.1661 | 0.0447 | 0.5165 | 0.8745 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0047 | 0.0004 | 0.0231 | 0.0107 | 0.0658 | 0.0258 | 0.0594 | 0.0103 | 0.0912 | 0.0214 | 0.7556 | 0.9315 | 0.0000 | 0.0057 | 0.0056 | 0.0230 | 0.0169 | 0.1092 | 0.0666 | 0.1782 | 0.1332 | 0.1494 | 0.1603 | 0.1839 | 0.0971 | 0.1149 | 0.1332 | 0.0977 | 0.3871 | 0.1379 | 0.0013 | 0.0051 | 0.0161 | 0.0442 | 0.0794 | 0.1219 | 0.0968 | 0.1125 | 0.5227 | 6 | 8 | 10 | 15 | 37 | 76 | 132 | 208 | 298 | 0.0817 | 10.67 | 4.715 | 0.5608 | 26243.7 | 8800000 | 3420000000 | 1480000000000 | 0.4564 | 0.1723 | 0.0249 | 0.0017 | 0.0817 | 0.0059 | 0.2664 | 0.0462 | 0.2433 | 0.0891 | 0.1456 | 0.1756 | 0.1155 | 0.2311 | 0.0639 | 0.1395 | 0.0373 | 0.1218 | 0.0213 | 0.1891 | 0.0007 | 0.0003 | 0.0007 | 0.0006 | 0.0029 | 0.0015 | 0.0098 | 0.0052 | 0.0334 | 0.0268 | 0.0579 | 0.0534 | 0.0435 | 0.0365 | 0.0648 | 0.0589 | 0.7863 | 0.8169 | 0.0008 | 0.0000 | 0.0000 | 0.0004 | 0.0016 | 0.0009 | 0.0148 | 0.0152 | 0.0409 | 0.0567 | 0.0678 | 0.0844 | 0.0650 | 0.0612 | 0.0770 | 0.0933 | 0.7319 | 0.6878 | 0.0004 | 0.0015 | 0.0025 | 0.0105 | 0.0384 | 0.0613 | 0.0537 | 0.0758 | 0.7560 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 395 | 643 | | 5110 | 12647 | 411.8 | 82.88 | 98.24 | 223.44 | 296 | 332 | 362 | 387 | 413 | 442 | 469 | 492 | 516 | 0.0659 | 833 | 1.130 | 86.12 | 29.43 | 1 | 0.0421 | 215 | 0.0017 | 11.85 | 6.634 | 0.3156 | 176415.0 | 78200000 | 35700000000 | 16700000000000 | 0.4107 | 0.2254 | 0.0009 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0000 | 0.0133 | 0.0006 | 0.0344 | 0.0142 | 0.0667 | 0.0259 | 0.0689 | 0.0150 | 0.0910 | 0.0273 | 0.7153 | 0.9170 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0027 | 0.0000 | 0.0046 | 0.0006 | 0.0126 | 0.0131 | 0.0239 | 0.0224 | 0.0220 | 0.0115 | 0.0305 | 0.0206 | 0.9023 | 0.9318 | 0.0041 | 0.0000 | 0.0072 | 0.1290 | 0.0103 | 0.1935 | 0.0351 | 0.1290 | 0.0784 | 0.2258 | 0.0991 | 0.2258 | 0.0877 | 0.0645 | 0.1290 | 0.0323 | 0.5490 | 0.0000 | 0.0004 | 0.0043 | 0.0031 | 0.0105 | 0.0233 | 0.0361 | 0.0415 | 0.0562 | 0.8247 | 7 | 8 | 10 | 11 | 13 | 16 | 30 | 87 | 318 | 0.2398 | 18.28 | 3.252 | 0.6811 | 59570.0 | 56500000 | 65600000000 | 86800000000000 | 0.3448 | 0.2408 | 0.0274 | 0.0023 | 0.1471 | 0.0150 | 0.2893 | 0.0495 | 0.1845 | 0.1164 | 0.1621 | 0.2085 | 0.0998 | 0.2385 | 0.0299 | 0.1336 | 0.0324 | 0.1083 | 0.0274 | 0.1279 | 0.0000 | 0.0007 | 0.0004 | 0.0007 | 0.0015 | 0.0020 | 0.0091 | 0.0078 | 0.0380 | 0.0346 | 0.0673 | 0.0620 | 0.0395 | 0.0400 | 0.0589 | 0.0491 | 0.7852 | 0.8032 | 0.0009 | 0.0005 | 0.0040 | 0.0010 | 0.0040 | 0.0024 | 0.0094 | 0.0086 | 0.0395 | 0.0427 | 0.0686 | 0.0734 | 0.0413 | 0.0504 | 0.0659 | 0.0705 | 0.7663 | 0.7505 | 0.0004 | 0.0013 | 0.0042 | 0.0129 | 0.0400 | 0.0642 | 0.0396 | 0.0554 | 0.7821 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 477 | 426 | | 5377 | 19317 | 581.1 | 160.29 | 136.17 | 209.41 | 425 | 459 | 484 | 509 | 534 | 566 | 617 | 705 | 822 | 0.0467 | 902 | 1.031 | 97.32 | 27.29 | 2 | 0.0433 | 233 | 0.0008 | 63.73 | 7.412 | 0.1708 | 363397.0 | 246000000 | 181000000000 | 144000000000000 | 0.3855 | 0.2619 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0029 | 0.0002 | 0.0165 | 0.0025 | 0.0836 | 0.0253 | 0.1454 | 0.0498 | 0.1535 | 0.0451 | 0.1707 | 0.0641 | 0.4266 | 0.8129 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0048 | 0.0002 | 0.0452 | 0.0152 | 0.0767 | 0.0238 | 0.0829 | 0.0208 | 0.1093 | 0.0315 | 0.6802 | 0.9084 | 0.0018 | 0.0000 | 0.0018 | 0.0068 | 0.0063 | 0.0068 | 0.0288 | 0.0342 | 0.0728 | 0.1182 | 0.1150 | 0.1541 | 0.0584 | 0.0908 | 0.0988 | 0.1404 | 0.6164 | 0.4486 | 0.0015 | 0.0026 | 0.0128 | 0.0271 | 0.0767 | 0.1048 | 0.0772 | 0.0905 | 0.6069 | 6 | 8 | 9 | 12 | 19 | 59 | 148 | 254 | 436 | 0.1238 | 34.07 | 4.718 | 0.5673 | 62391.7 | 40700000 | 33200000000 | 32300000000000 | 0.4255 | 0.1972 | 0.0345 | 0.0023 | 0.1373 | 0.0110 | 0.2596 | 0.0799 | 0.2092 | 0.1106 | 0.1690 | 0.2037 | 0.1018 | 0.1992 | 0.0495 | 0.1293 | 0.0271 | 0.1275 | 0.0121 | 0.1366 | 0.0003 | 0.0000 | 0.0005 | 0.0001 | 0.0009 | 0.0000 | 0.0059 | 0.0038 | 0.0367 | 0.0320 | 0.0589 | 0.0488 | 0.0443 | 0.0411 | 0.0677 | 0.0553 | 0.7847 | 0.8190 | 0.0002 | 0.0002 | 0.0002 | 0.0014 | 0.0007 | 0.0008 | 0.0100 | 0.0122 | 0.0407 | 0.0531 | 0.0851 | 0.0882 | 0.0557 | 0.0635 | 0.0838 | 0.0904 | 0.7235 | 0.6902 | 0.0000 | 0.0000 | 0.0005 | 0.0065 | 0.0403 | 0.0668 | 0.0522 | 0.0737 | 0.7600 | ||
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 245 | | 7441 | 18098 | 595.1 | 99.87 | 158.05 | 276.24 | 459 | 515 | 549 | 576 | 598 | 618 | 640 | 669 | 725 | 0.0530 | 960 | 0.791 | 112.90 | 27.89 | 2 | 0.0372 | 277 | 0.0011 | 26.39 | 7.165 | 0.2288 | 364116.0 | 229000000 | 147000000000 | 96900000000000 | 0.4475 | 0.1984 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0016 | 0.0000 | 0.0053 | 0.0005 | 0.0258 | 0.0124 | 0.0455 | 0.0206 | 0.0458 | 0.0151 | 0.0692 | 0.0230 | 0.8059 | 0.9282 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0003 | 0.0163 | 0.0116 | 0.0267 | 0.0174 | 0.0252 | 0.0115 | 0.0358 | 0.0181 | 0.8938 | 0.9412 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0292 | 0.0000 | 0.0560 | 0.0000 | 0.0840 | 0.0000 | 0.0793 | 0.0000 | 0.1039 | 0.0000 | 0.6196 | 0.0000 | 0.0018 | 0.0036 | 0.0094 | 0.0214 | 0.0420 | 0.0641 | 0.0646 | 0.0876 | 0.7055 | 11 | 14 | 17 | 20 | 25 | 35 | 85 | 239 | 575 | 0.1535 | 16.74 | 4.037 | 0.6476 | 101285.0 | 90600000 | 95000000000 | 112000000000000 | 0.3437 | 0.2785 | 0.0470 | 0.0020 | 0.1678 | 0.0214 | 0.1893 | 0.0935 | 0.1530 | 0.1136 | 0.1732 | 0.1877 | 0.0980 | 0.1717 | 0.0779 | 0.1236 | 0.0671 | 0.1142 | 0.0268 | 0.1723 | 0.0002 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0013 | 0.0102 | 0.0086 | 0.0376 | 0.0335 | 0.0599 | 0.0539 | 0.0436 | 0.0392 | 0.0626 | 0.0588 | 0.7843 | 0.8046 | 0.0000 | 0.0003 | 0.0012 | 0.0000 | 0.0042 | 0.0040 | 0.0138 | 0.0138 | 0.0413 | 0.0458 | 0.0655 | 0.0684 | 0.0487 | 0.0468 | 0.0667 | 0.0620 | 0.7586 | 0.7589 | 0.0002 | 0.0007 | 0.0023 | 0.0114 | 0.0416 | 0.0654 | 0.0444 | 0.0633 | 0.7707 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 621 | 832 | | 10045 | 16653 | 624.4 | 136.14 | 146.38 | 247.89 | 478 | 513 | 544 | 571 | 595 | 625 | 662 | 712 | 830 | 0.0671 | 1118 | 1.208 | 132.46 | 56.89 | 1 | 0.0353 | 355 | 0.0011 | 29.04 | 7.171 | 0.2381 | 408412.0 | 281000000 | 204000000000 | 157000000000000 | 0.4086 | 0.2413 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0007 | 0.0125 | 0.0016 | 0.0328 | 0.0154 | 0.0584 | 0.0291 | 0.0670 | 0.0221 | 0.0956 | 0.0345 | 0.7297 | 0.8966 | 0.0005 | 0.0000 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0072 | 0.0002 | 0.0161 | 0.0088 | 0.0293 | 0.0152 | 0.0349 | 0.0084 | 0.0505 | 0.0148 | 0.8595 | 0.9526 | 0.0006 | 0.0029 | 0.0069 | 0.0073 | 0.0075 | 0.0190 | 0.0162 | 0.0321 | 0.0643 | 0.1226 | 0.0899 | 0.1431 | 0.0762 | 0.1080 | 0.1043 | 0.1328 | 0.6340 | 0.4321 | 0.0025 | 0.0025 | 0.0069 | 0.0195 | 0.0468 | 0.0683 | 0.0678 | 0.0849 | 0.7009 | 4 | 5 | 6 | 8 | 10 | 19 | 116 | 297 | 537 | 0.1488 | 72.06 | 4.406 | 0.5290 | 82870.7 | 61800000 | 54900000000 | 56100000000000 | 0.4135 | 0.2138 | 0.0751 | 0.0057 | 0.2521 | 0.0378 | 0.2654 | 0.1946 | 0.1669 | 0.1626 | 0.1135 | 0.1847 | 0.0785 | 0.1782 | 0.0234 | 0.1043 | 0.0200 | 0.0796 | 0.0050 | 0.0525 | 0.0000 | 0.0004 | 0.0008 | 0.0011 | 0.0014 | 0.0009 | 0.0050 | 0.0058 | 0.0321 | 0.0227 | 0.0675 | 0.0676 | 0.0431 | 0.0353 | 0.0673 | 0.0584 | 0.7827 | 0.8076 | 0.0009 | 0.0002 | 0.0005 | 0.0005 | 0.0023 | 0.0017 | 0.0068 | 0.0076 | 0.0390 | 0.0463 | 0.0847 | 0.0926 | 0.0513 | 0.0638 | 0.0884 | 0.0938 | 0.7262 | 0.6935 | 0.0000 | 0.0006 | 0.0023 | 0.0088 | 0.0301 | 0.0818 | 0.0496 | 0.0716 | 0.7552 | ||
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1178 | 149 | | 2587 | 12832 | 62.1 | 10.66 | 74.22 | 169.03 | 47 | 54 | 57 | 60 | 63 | 65 | 68 | 71 | 75 | 0.0646 | 829 | 0.944 | 80.06 | 19.03 | 2 | 0.0723 | 187 | 0.0369 | 1.29 | 3.638 | 0.6360 | 3969.1 | 260301 | 17500000 | 1200000000 | 0.4305 | 0.2137 | 0.0020 | 0.0000 | 0.0020 | 0.0004 | 0.0055 | 0.0008 | 0.0201 | 0.0075 | 0.0472 | 0.0210 | 0.0693 | 0.0334 | 0.0844 | 0.0346 | 0.1920 | 0.0516 | 0.5774 | 0.8507 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0079 | 0.0059 | 0.0238 | 0.0192 | 0.0331 | 0.0298 | 0.0348 | 0.0271 | 0.0591 | 0.0365 | 0.8386 | 0.8811 | 0.0719 | 0.0968 | 0.1079 | 0.1290 | 0.0755 | 0.1935 | 0.1151 | 0.0968 | 0.1043 | 0.1613 | 0.1187 | 0.1613 | 0.1475 | 0.0968 | 0.0827 | 0.0645 | 0.1763 | 0.0000 | 0.0036 | 0.0107 | 0.0220 | 0.0377 | 0.0519 | 0.0732 | 0.1087 | 0.1741 | 0.5181 | 15 | 19 | 23 | 28 | 32 | 38 | 43 | 50 | 94 | 0.1646 | 3.32 | 2.652 | 0.8090 | 34078.2 | 30400000 | 31700000000 | 35800000000000 | 0.6942 | 0.0754 | 0.1033 | 0.0274 | 0.0813 | 0.0364 | 0.0769 | 0.0502 | 0.0769 | 0.0707 | 0.1319 | 0.1021 | 0.1275 | 0.1360 | 0.1319 | 0.1585 | 0.1275 | 0.1667 | 0.1429 | 0.2520 | 0.0237 | 0.0180 | 0.0188 | 0.0239 | 0.0094 | 0.0319 | 0.0066 | 0.0430 | 0.0248 | 0.0663 | 0.0370 | 0.0857 | 0.0304 | 0.1021 | 0.0679 | 0.1201 | 0.7815 | 0.5089 | 0.0044 | 0.0017 | 0.0044 | 0.0035 | 0.0074 | 0.0095 | 0.0118 | 0.0173 | 0.0376 | 0.0528 | 0.0516 | 0.0692 | 0.0553 | 0.0614 | 0.1061 | 0.0882 | 0.7214 | 0.6964 | 0.0006 | 0.0038 | 0.0038 | 0.0101 | 0.0258 | 0.0396 | 0.0491 | 0.0931 | 0.7742 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 406 | 806 | | 3869 | 9909 | 688.7 | 123.70 | 61.45 | 130.52 | 523 | 588 | 635 | 670 | 698 | 722 | 743 | 770 | 857 | 0.0768 | 761 | 1.128 | 89.45 | 33.12 | 2 | 0.0605 | 234 | 0.0009 | 60.15 | 7.294 | 0.1719 | 489556.0 | 358000000 | 269000000000 | 207000000000000 | 0.3551 | 0.2759 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0039 | 0.0005 | 0.0389 | 0.0191 | 0.0470 | 0.0343 | 0.0473 | 0.0252 | 0.0666 | 0.0433 | 0.7950 | 0.8776 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0021 | 0.0005 | 0.0251 | 0.0187 | 0.0338 | 0.0305 | 0.0311 | 0.0174 | 0.0429 | 0.0274 | 0.8639 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0217 | 0.0000 | 0.0522 | 0.0000 | 0.0435 | 0.0000 | 0.0783 | 0.0000 | 0.0696 | 0.0000 | 0.7348 | 0.0000 | 0.0005 | 0.0014 | 0.0048 | 0.0144 | 0.0393 | 0.0672 | 0.0561 | 0.0859 | 0.7303 | 6 | 8 | 9 | 10 | 11 | 13 | 21 | 63 | 186 | 0.1948 | 6.58 | 2.831 | 0.6506 | 20808.7 | 11500000 | 7940000000 | 6280000000000 | 0.3866 | 0.2159 | 0.0387 | 0.0072 | 0.1613 | 0.0273 | 0.2355 | 0.1164 | 0.2065 | 0.1193 | 0.1839 | 0.1379 | 0.0903 | 0.1897 | 0.0548 | 0.1149 | 0.0194 | 0.1379 | 0.0097 | 0.1494 | 0.0005 | 0.0000 | 0.0005 | 0.0008 | 0.0009 | 0.0004 | 0.0147 | 0.0132 | 0.0372 | 0.0371 | 0.0689 | 0.0556 | 0.0358 | 0.0342 | 0.0611 | 0.0671 | 0.7804 | 0.7917 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0032 | 0.0017 | 0.0118 | 0.0121 | 0.0428 | 0.0537 | 0.0707 | 0.0779 | 0.0386 | 0.0467 | 0.0739 | 0.0848 | 0.7590 | 0.7213 | 0.0005 | 0.0005 | 0.0020 | 0.0125 | 0.0435 | 0.0659 | 0.0390 | 0.0649 | 0.7712 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 524 | 311 | | 7833 | 16316 | 159.4 | 129.05 | 84.65 | 174.06 | 65 | 76 | 86 | 97 | 114 | 131 | 150 | 185 | 382 | 0.0834 | 1360 | 1.188 | 60.96 | 23.71 | 5 | 0.0200 | 157 | 0.0057 | 7.18 | 5.903 | 0.4831 | 42052.4 | 16100000 | 7440000000 | 3750000000000 | 0.4134 | 0.2024 | 0.0022 | 0.0044 | 0.0039 | 0.0032 | 0.0061 | 0.0041 | 0.0335 | 0.0116 | 0.0754 | 0.0367 | 0.0972 | 0.0576 | 0.0972 | 0.0547 | 0.1056 | 0.0789 | 0.5788 | 0.7488 | 0.0012 | 0.0031 | 0.0021 | 0.0023 | 0.0027 | 0.0029 | 0.0140 | 0.0079 | 0.0273 | 0.0211 | 0.0334 | 0.0280 | 0.0404 | 0.0320 | 0.0507 | 0.0445 | 0.8282 | 0.8580 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0033 | 0.0000 | 0.0086 | 0.0022 | 0.0213 | 0.0230 | 0.0452 | 0.0445 | 0.0219 | 0.0208 | 0.0359 | 0.0408 | 0.8625 | 0.8687 | 0.0005 | 0.0039 | 0.0043 | 0.0096 | 0.0294 | 0.0487 | 0.0352 | 0.0545 | 0.8140 | 8 | 10 | 12 | 15 | 18 | 24 | 39 | 87 | 242 | 0.1992 | 8.64 | 2.988 | 0.7068 | 37461.6 | 26400000 | 22100000000 | 20600000000000 | 0.5330 | 0.1352 | 0.0090 | 0.0029 | 0.0336 | 0.0070 | 0.0493 | 0.0187 | 0.1087 | 0.0531 | 0.1659 | 0.0904 | 0.1839 | 0.1376 | 0.1390 | 0.1405 | 0.1312 | 0.1359 | 0.1794 | 0.4140 | 0.0005 | 0.0009 | 0.0029 | 0.0023 | 0.0029 | 0.0042 | 0.0098 | 0.0168 | 0.0383 | 0.0349 | 0.0554 | 0.0519 | 0.0449 | 0.0496 | 0.0660 | 0.0575 | 0.7794 | 0.7817 | 0.0021 | 0.0004 | 0.0017 | 0.0035 | 0.0045 | 0.0047 | 0.0141 | 0.0116 | 0.0497 | 0.0520 | 0.0783 | 0.0849 | 0.0583 | 0.0621 | 0.0852 | 0.0791 | 0.7060 | 0.7017 | 0.0009 | 0.0033 | 0.0045 | 0.0117 | 0.0415 | 0.0667 | 0.0505 | 0.0739 | 0.7471 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 913 | 210 | | 8143 | 27204 | 304.1 | 75.81 | 255.15 | 302.47 | 195 | 245 | 273 | 292 | 310 | 328 | 348 | 371 | 396 | 0.0396 | 1076 | 1.114 | 110.82 | 43.01 | 5 | 0.0373 | 304 | 0.0010 | 29.98 | 7.166 | 0.2157 | 98209.8 | 33200000 | 11600000000 | 4170000000000 | 0.4037 | 0.2325 | 0.0006 | 0.0000 | 0.0017 | 0.0000 | 0.0087 | 0.0001 | 0.0205 | 0.0021 | 0.0499 | 0.0164 | 0.0838 | 0.0287 | 0.0889 | 0.0302 | 0.1235 | 0.0508 | 0.6224 | 0.8717 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0037 | 0.0011 | 0.0125 | 0.0105 | 0.0220 | 0.0168 | 0.0235 | 0.0118 | 0.0341 | 0.0168 | 0.9030 | 0.9431 | 0.0027 | 0.0366 | 0.0038 | 0.0549 | 0.0215 | 0.0623 | 0.0447 | 0.1282 | 0.0910 | 0.2051 | 0.1319 | 0.1722 | 0.1179 | 0.1612 | 0.1524 | 0.0989 | 0.4340 | 0.0806 | 0.0014 | 0.0032 | 0.0069 | 0.0123 | 0.0407 | 0.0638 | 0.0782 | 0.0981 | 0.6954 | 11 | 17 | 29 | 55 | 110 | 207 | 346 | 511 | 718 | 0.0322 | 37.90 | 6.066 | 0.4425 | 156585.0 | 127000000 | 124000000000 | 141000000000000 | 0.4560 | 0.1894 | 0.0158 | 0.0005 | 0.0981 | 0.0072 | 0.2220 | 0.0341 | 0.1823 | 0.1004 | 0.1923 | 0.1873 | 0.1306 | 0.2205 | 0.0775 | 0.1404 | 0.0464 | 0.1380 | 0.0349 | 0.1716 | 0.0002 | 0.0001 | 0.0006 | 0.0008 | 0.0034 | 0.0020 | 0.0077 | 0.0080 | 0.0389 | 0.0364 | 0.0615 | 0.0565 | 0.0439 | 0.0435 | 0.0653 | 0.0602 | 0.7784 | 0.7924 | 0.0005 | 0.0004 | 0.0011 | 0.0013 | 0.0019 | 0.0025 | 0.0109 | 0.0122 | 0.0412 | 0.0488 | 0.0778 | 0.0819 | 0.0567 | 0.0645 | 0.0835 | 0.0869 | 0.7263 | 0.7017 | 0.0003 | 0.0012 | 0.0026 | 0.0088 | 0.0373 | 0.0681 | 0.0507 | 0.0713 | 0.7596 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 640 | 647 | | 6376 | 20211 | 467.1 | 97.26 | 74.59 | 104.47 | 355 | 384 | 407 | 429 | 451 | 477 | 504 | 541 | 602 | 0.0495 | 1000 | 0.965 | 107.82 | 31.58 | 1 | 0.0402 | 256 | 0.0008 | 48.43 | 7.332 | 0.1727 | 227685.0 | 116000000 | 61700000000 | 34200000000000 | 0.4323 | 0.2096 | 0.0005 | 0.0000 | 0.0005 | 0.0002 | 0.0030 | 0.0000 | 0.0118 | 0.0013 | 0.0469 | 0.0161 | 0.0999 | 0.0336 | 0.1154 | 0.0239 | 0.1501 | 0.0351 | 0.5720 | 0.8897 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0063 | 0.0002 | 0.0211 | 0.0111 | 0.0446 | 0.0196 | 0.0504 | 0.0108 | 0.0759 | 0.0166 | 0.7993 | 0.9416 | 0.0039 | 0.0000 | 0.0068 | 0.0084 | 0.0193 | 0.0169 | 0.0501 | 0.0478 | 0.1157 | 0.1348 | 0.1533 | 0.1573 | 0.0984 | 0.1152 | 0.1215 | 0.1348 | 0.4311 | 0.3848 | 0.0004 | 0.0014 | 0.0086 | 0.0280 | 0.0714 | 0.1288 | 0.1065 | 0.1352 | 0.5197 | 7 | 8 | 9 | 11 | 16 | 39 | 83 | 140 | 227 | 0.1404 | 11.27 | 4.303 | 0.6000 | 16476.9 | 5110000 | 1900000000 | 803000000000 | 0.4799 | 0.1508 | 0.0373 | 0.0004 | 0.1664 | 0.0126 | 0.2806 | 0.0605 | 0.1730 | 0.1438 | 0.1498 | 0.2138 | 0.1068 | 0.2197 | 0.0397 | 0.1363 | 0.0281 | 0.1023 | 0.0182 | 0.1106 | 0.0003 | 0.0001 | 0.0003 | 0.0006 | 0.0006 | 0.0010 | 0.0070 | 0.0080 | 0.0388 | 0.0338 | 0.0642 | 0.0584 | 0.0456 | 0.0429 | 0.0655 | 0.0588 | 0.7778 | 0.7963 | 0.0000 | 0.0010 | 0.0005 | 0.0002 | 0.0012 | 0.0013 | 0.0093 | 0.0155 | 0.0514 | 0.0530 | 0.0784 | 0.0890 | 0.0588 | 0.0718 | 0.0916 | 0.0918 | 0.7088 | 0.6764 | 0.0000 | 0.0000 | 0.0019 | 0.0069 | 0.0418 | 0.0702 | 0.0519 | 0.0787 | 0.7487 | ||
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 296 | 572 | | 8086 | 26684 | 302.2 | 79.97 | 205.86 | 280.95 | 205 | 239 | 262 | 283 | 304 | 326 | 349 | 373 | 401 | 0.0475 | 1267 | 0.665 | 59.68 | 11.31 | 3 | 0.0177 | 143 | 0.0008 | 40.70 | 7.343 | 0.1978 | 97719.6 | 33200000 | 11800000000 | 4310000000000 | 0.3795 | 0.2472 | 0.0011 | 0.0000 | 0.0016 | 0.0000 | 0.0074 | 0.0003 | 0.0207 | 0.0023 | 0.0767 | 0.0172 | 0.1294 | 0.0437 | 0.1280 | 0.0397 | 0.1701 | 0.0578 | 0.4650 | 0.8391 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0012 | 0.0212 | 0.0116 | 0.0426 | 0.0234 | 0.0420 | 0.0137 | 0.0672 | 0.0206 | 0.8188 | 0.9295 | 0.0020 | 0.0068 | 0.0051 | 0.0228 | 0.0164 | 0.0387 | 0.0475 | 0.1048 | 0.0915 | 0.2096 | 0.1539 | 0.1891 | 0.1099 | 0.1071 | 0.1595 | 0.1344 | 0.4141 | 0.1868 | 0.0002 | 0.0041 | 0.0090 | 0.0124 | 0.0506 | 0.0812 | 0.0669 | 0.0846 | 0.6910 | 12 | 15 | 18 | 23 | 51 | 133 | 250 | 395 | 618 | 0.1321 | 29.66 | 4.846 | 0.5609 | 121307.0 | 98300000 | 95600000000 | 106000000000000 | 0.3068 | 0.3447 | 0.0442 | 0.0016 | 0.1546 | 0.0133 | 0.2155 | 0.0891 | 0.1482 | 0.1397 | 0.1751 | 0.1708 | 0.1401 | 0.1937 | 0.0636 | 0.1158 | 0.0442 | 0.1223 | 0.0145 | 0.1536 | 0.0006 | 0.0000 | 0.0012 | 0.0004 | 0.0031 | 0.0022 | 0.0115 | 0.0116 | 0.0386 | 0.0343 | 0.0571 | 0.0510 | 0.0451 | 0.0319 | 0.0658 | 0.0520 | 0.7769 | 0.8165 | 0.0007 | 0.0010 | 0.0026 | 0.0022 | 0.0043 | 0.0052 | 0.0155 | 0.0182 | 0.0500 | 0.0581 | 0.0812 | 0.0876 | 0.0644 | 0.0690 | 0.0894 | 0.1000 | 0.6918 | 0.6586 | 0.0002 | 0.0011 | 0.0040 | 0.0169 | 0.0395 | 0.0700 | 0.0579 | 0.0782 | 0.7322 |
| MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 945 | 791 | | 7136 | 8653 | 396.4 | 68.86 | 331.09 | 487.17 | 292 | 338 | 365 | 386 | 406 | 423 | 439 | 454 | 478 | 0.0953 | 825 | 1.046 | 109.66 | 38.48 | 6 | 0.0419 | 299 | 0.0024 | 9.08 | 6.362 | 0.3660 | 161888.0 | 67800000 | 29000000000 | 12700000000000 | 0.4181 | 0.2153 | 0.0006 | 0.0000 | 0.0015 | 0.0000 | 0.0038 | 0.0000 | 0.0079 | 0.0011 | 0.0218 | 0.0106 | 0.0533 | 0.0271 | 0.0385 | 0.0132 | 0.0585 | 0.0186 | 0.8142 | 0.9294 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0011 | 0.0113 | 0.0105 | 0.0289 | 0.0260 | 0.0141 | 0.0119 | 0.0204 | 0.0173 | 0.9222 | 0.9333 | 0.0066 | 0.0000 | 0.0066 | 0.0000 | 0.0263 | 0.0000 | 0.0447 | 0.0000 | 0.1092 | 0.0000 | 0.1184 | 0.0000 | 0.1158 | 0.0000 | 0.1382 | 0.0000 | 0.4342 | 0.0000 | 0.0005 | 0.0015 | 0.0051 | 0.0101 | 0.0281 | 0.0398 | 0.0367 | 0.0529 | 0.8252 | 10 | 12 | 15 | 26 | 85 | 211 | 381 | 631 | 998 | 0.1055 | 26.80 | 5.014 | 0.5502 | 346927.0 | 541000000 | 1110000000000 | 2.77E+15 | 0.4761 | 0.1685 | 0.0161 | 0.0031 | 0.0966 | 0.0086 | 0.1804 | 0.0350 | 0.1739 | 0.0871 | 0.1643 | 0.1540 | 0.1433 | 0.1882 | 0.0934 | 0.1407 | 0.0805 | 0.1198 | 0.0515 | 0.2636 | 0.0003 | 0.0008 | 0.0006 | 0.0014 | 0.0025 | 0.0017 | 0.0063 | 0.0068 | 0.0348 | 0.0256 | 0.0659 | 0.0501 | 0.0446 | 0.0400 | 0.0681 | 0.0535 | 0.7768 | 0.8202 | 0.0000 | 0.0004 | 0.0004 | 0.0018 | 0.0039 | 0.0049 | 0.0102 | 0.0123 | 0.0481 | 0.0511 | 0.0777 | 0.0886 | 0.0560 | 0.0675 | 0.0765 | 0.0825 | 0.7272 | 0.6909 | 0.0000 | 0.0004 | 0.0036 | 0.0093 | 0.0411 | 0.0750 | 0.0496 | 0.0650 | 0.7562 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1215 | 337 | | 5299 | 15208 | 314.6 | 49.18 | 289.78 | 445.68 | 258 | 273 | 285 | 295 | 306 | 318 | 334 | 356 | 383 | 0.0592 | 900 | 0.916 | 116.83 | 42.76 | 1 | 0.0670 | 355 | 0.0017 | 23.16 | 6.655 | 0.2317 | 101403.0 | 33500000 | 11400000000 | 3950000000000 | 0.3986 | 0.2511 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0000 | 0.0093 | 0.0002 | 0.0305 | 0.0140 | 0.0753 | 0.0305 | 0.0827 | 0.0190 | 0.1286 | 0.0295 | 0.6705 | 0.9068 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0000 | 0.0158 | 0.0117 | 0.0404 | 0.0247 | 0.0404 | 0.0102 | 0.0640 | 0.0160 | 0.8348 | 0.9373 | 0.0063 | 0.0000 | 0.0158 | 0.0000 | 0.0412 | 0.0000 | 0.0824 | 0.0000 | 0.1173 | 0.0000 | 0.1347 | 0.0000 | 0.1094 | 0.0000 | 0.1410 | 0.0000 | 0.3518 | 0.0000 | 0.0022 | 0.0083 | 0.0188 | 0.0419 | 0.0777 | 0.1104 | 0.0877 | 0.1144 | 0.5386 | 14 | 17 | 20 | 24 | 37 | 96 | 310 | 568 | 955 | 0.0512 | 92.27 | 5.412 | 0.4889 | 282587.0 | 374000000 | 589000000000 | 1.04E+15 | 0.4260 | 0.2078 | 0.0678 | 0.0021 | 0.2554 | 0.0310 | 0.2713 | 0.1590 | 0.1515 | 0.1654 | 0.1154 | 0.1977 | 0.0736 | 0.1668 | 0.0375 | 0.0880 | 0.0202 | 0.0992 | 0.0072 | 0.0908 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0006 | 0.0002 | 0.0058 | 0.0039 | 0.0392 | 0.0362 | 0.0676 | 0.0614 | 0.0464 | 0.0369 | 0.0642 | 0.0614 | 0.7760 | 0.7994 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0016 | 0.0038 | 0.0107 | 0.0111 | 0.0513 | 0.0494 | 0.0801 | 0.0970 | 0.0632 | 0.0688 | 0.0880 | 0.0932 | 0.7051 | 0.6762 | 0.0000 | 0.0000 | 0.0009 | 0.0068 | 0.0458 | 0.0717 | 0.0503 | 0.0824 | 0.7421 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 248 | 500 | | 1039 | 2688 | 496.1 | 98.73 | 39.06 | 62.95 | 376 | 424 | 458 | 485 | 504 | 521 | 536 | 562 | 631 | 0.1365 | 367 | 0.740 | 130.00 | 22.83 | 1 | 0.2849 | 296 | 0.0017 | 65.54 | 6.527 | 0.1617 | 255811.0 | 136000000 | 73900000000 | 41200000000000 | 0.4036 | 0.2366 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0020 | 0.0499 | 0.0318 | 0.0823 | 0.0417 | 0.0702 | 0.0328 | 0.0931 | 0.0557 | 0.6991 | 0.8360 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0020 | 0.0324 | 0.0307 | 0.0525 | 0.0396 | 0.0357 | 0.0277 | 0.0558 | 0.0455 | 0.8225 | 0.8546 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0065 | 0.6000 | 0.0258 | 0.2000 | 0.0710 | 0.0000 | 0.0903 | 0.0000 | 0.0645 | 0.0000 | 0.1032 | 0.0000 | 0.6387 | 0.0000 | 0.0000 | 0.0017 | 0.0017 | 0.0174 | 0.0522 | 0.0922 | 0.0783 | 0.0939 | 0.6626 | 7 | 8 | 10 | 13 | 15 | 18 | 23 | 43 | 112 | 0.1239 | 2.12 | 3.167 | 0.7441 | 5486.9 | 1350000 | 417000000 | 146000000000 | 0.5373 | 0.1116 | 0.0154 | 0.0541 | 0.0538 | 0.0510 | 0.0846 | 0.0318 | 0.1231 | 0.0701 | 0.1231 | 0.0987 | 0.2077 | 0.0955 | 0.1462 | 0.1178 | 0.1538 | 0.2102 | 0.0923 | 0.2707 | 0.0031 | 0.0211 | 0.0108 | 0.0199 | 0.0093 | 0.0112 | 0.0170 | 0.0211 | 0.0216 | 0.0373 | 0.0386 | 0.0398 | 0.0448 | 0.0460 | 0.0802 | 0.1007 | 0.7747 | 0.7027 | 0.0039 | 0.0020 | 0.0039 | 0.0000 | 0.0019 | 0.0041 | 0.0135 | 0.0122 | 0.0251 | 0.0245 | 0.0290 | 0.0306 | 0.0444 | 0.0510 | 0.0734 | 0.0592 | 0.8050 | 0.8163 | 0.0070 | 0.0053 | 0.0088 | 0.0140 | 0.0298 | 0.0385 | 0.0403 | 0.0788 | 0.7776 |