High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 946 | 255 | | 1237 | 5097 | 597.6 | 154.71 | 26.89 | 29.04 | 397 | 436 | 482 | 531 | 589 | 647 | 701 | 753 | 822 | 0.1214 | 619 | 1.247 | 102.24 | 42.95 | 1 | 0.2183 | 270 | 0.0018 | 17.17 | 6.438 | 0.2538 | 381056.0 | 257000000 | 181000000000 | 133000000000000 | 0.3962 | 0.2297 | 0.0000 | 0.0000 | 0.0037 | 0.0009 | 0.0093 | 0.0018 | 0.0223 | 0.0080 | 0.0801 | 0.0312 | 0.1657 | 0.0714 | 0.1192 | 0.0562 | 0.1546 | 0.0714 | 0.4451 | 0.7591 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0092 | 0.0016 | 0.0264 | 0.0246 | 0.0608 | 0.0493 | 0.0321 | 0.0271 | 0.0585 | 0.0427 | 0.8131 | 0.8539 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0060 | 0.0412 | 0.0269 | 0.0619 | 0.0716 | 0.1443 | 0.1134 | 0.1753 | 0.0866 | 0.0825 | 0.0925 | 0.1753 | 0.6030 | 0.2887 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0634 | 0.0467 | 0.0768 | 0.7596 | 6 | 7 | 8 | 10 | 13 | 19 | 28 | 45 | 74 | 0.1481 | 0.93 | 2.851 | 0.7106 | 1566.2 | 129062 | 12400000 | 1310000000 | 0.4006 | 0.2163 | 0.0291 | 0.0139 | 0.1414 | 0.0268 | 0.2557 | 0.0606 | 0.2370 | 0.1480 | 0.1705 | 0.2205 | 0.1019 | 0.1768 | 0.0437 | 0.1609 | 0.0146 | 0.1231 | 0.0062 | 0.0695 | 0.0016 | 0.0054 | 0.0022 | 0.0054 | 0.0141 | 0.0117 | 0.0255 | 0.0252 | 0.0662 | 0.0667 | 0.0950 | 0.0812 | 0.0787 | 0.0744 | 0.0944 | 0.1019 | 0.6224 | 0.6280 | 0.0029 | 0.0025 | 0.0059 | 0.0033 | 0.0095 | 0.0190 | 0.0352 | 0.0355 | 0.0808 | 0.0809 | 0.0932 | 0.0884 | 0.0712 | 0.0710 | 0.0991 | 0.1057 | 0.6021 | 0.5937 | 0.0025 | 0.0056 | 0.0124 | 0.0324 | 0.0678 | 0.1008 | 0.0716 | 0.0965 | 0.6105 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 146 | 887 | | 7631 | 21436 | 727.6 | 138.83 | 177.21 | 164.76 | 559 | 609 | 647 | 680 | 711 | 747 | 788 | 842 | 928 | 0.0466 | 999 | 1.151 | 109.39 | 39.66 | 3 | 0.0358 | 273 | 0.0005 | 96.74 | 7.799 | 0.1272 | 548709.0 | 428000000 | 346000000000 | 288000000000000 | 0.4347 | 0.2091 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0098 | 0.0011 | 0.0577 | 0.0148 | 0.1275 | 0.0300 | 0.1226 | 0.0286 | 0.1538 | 0.0479 | 0.5265 | 0.8776 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0040 | 0.0001 | 0.0261 | 0.0111 | 0.0570 | 0.0203 | 0.0558 | 0.0116 | 0.0815 | 0.0188 | 0.7746 | 0.9381 | 0.0024 | 0.0271 | 0.0065 | 0.0226 | 0.0212 | 0.1041 | 0.0637 | 0.1719 | 0.1371 | 0.1900 | 0.1853 | 0.1900 | 0.1273 | 0.1538 | 0.1510 | 0.0860 | 0.3053 | 0.0543 | 0.0020 | 0.0038 | 0.0116 | 0.0358 | 0.0832 | 0.1282 | 0.1170 | 0.1331 | 0.4854 | 19 | 36 | 62 | 97 | 135 | 178 | 225 | 286 | 389 | 0.0094 | 25.15 | 6.072 | 0.3627 | 58546.5 | 27800000 | 17200000000 | 13100000000000 | 0.4795 | 0.1685 | 0.0412 | 0.0013 | 0.1579 | 0.0105 | 0.2563 | 0.0772 | 0.1701 | 0.1359 | 0.1559 | 0.1808 | 0.1097 | 0.2006 | 0.0682 | 0.1460 | 0.0319 | 0.1267 | 0.0087 | 0.1208 | 0.0003 | 0.0003 | 0.0011 | 0.0011 | 0.0045 | 0.0011 | 0.0186 | 0.0128 | 0.0660 | 0.0509 | 0.1297 | 0.1018 | 0.1036 | 0.0883 | 0.1381 | 0.1190 | 0.5381 | 0.6246 | 0.0013 | 0.0031 | 0.0053 | 0.0081 | 0.0151 | 0.0171 | 0.0419 | 0.0463 | 0.0956 | 0.1170 | 0.1640 | 0.1725 | 0.1258 | 0.1325 | 0.1545 | 0.1478 | 0.3965 | 0.3555 | 0.0009 | 0.0027 | 0.0070 | 0.0268 | 0.0857 | 0.1465 | 0.1242 | 0.1468 | 0.4593 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 880 | 168 | | 38955 | 26240 | 163.7 | 54.42 | 189.84 | 155.38 | 92 | 114 | 132 | 148 | 164 | 179 | 194 | 210 | 233 | 0.1215 | 3188 | 0.799 | 74.95 | 17.03 | 13 | 0.0043 | 168 | 0.0008 | 32.80 | 7.366 | 0.2060 | 29769.9 | 5880000 | 1240000000 | 280000000000 | 0.5763 | 0.1150 | 0.0010 | 0.0002 | 0.0035 | 0.0005 | 0.0154 | 0.0020 | 0.0472 | 0.0094 | 0.1113 | 0.0378 | 0.1741 | 0.0717 | 0.1653 | 0.0787 | 0.1782 | 0.1069 | 0.3041 | 0.6929 | 0.0003 | 0.0001 | 0.0009 | 0.0002 | 0.0030 | 0.0009 | 0.0108 | 0.0048 | 0.0303 | 0.0203 | 0.0519 | 0.0341 | 0.0512 | 0.0327 | 0.0704 | 0.0446 | 0.7812 | 0.8624 | 0.0018 | 0.0076 | 0.0072 | 0.0135 | 0.0124 | 0.0327 | 0.0413 | 0.0819 | 0.0859 | 0.1325 | 0.1267 | 0.1726 | 0.1108 | 0.1197 | 0.1380 | 0.1307 | 0.4759 | 0.3088 | 0.0012 | 0.0016 | 0.0058 | 0.0209 | 0.0477 | 0.0807 | 0.0801 | 0.1009 | 0.6610 | 30 | 51 | 77 | 110 | 148 | 191 | 245 | 316 | 419 | 0.0043 | 23.31 | 6.446 | 0.3390 | 60178.8 | 24700000 | 11900000000 | 6310000000000 | 0.6103 | 0.0987 | 0.0154 | 0.0035 | 0.0720 | 0.0118 | 0.1491 | 0.0312 | 0.1825 | 0.0787 | 0.1846 | 0.1419 | 0.1799 | 0.1989 | 0.0982 | 0.1547 | 0.0673 | 0.1582 | 0.0509 | 0.2210 | 0.0009 | 0.0008 | 0.0043 | 0.0023 | 0.0067 | 0.0044 | 0.0211 | 0.0165 | 0.0660 | 0.0589 | 0.1135 | 0.1002 | 0.0823 | 0.0792 | 0.1052 | 0.1029 | 0.6000 | 0.6347 | 0.0009 | 0.0028 | 0.0066 | 0.0068 | 0.0095 | 0.0154 | 0.0324 | 0.0388 | 0.0825 | 0.0887 | 0.1348 | 0.1364 | 0.0914 | 0.0993 | 0.1153 | 0.1173 | 0.5266 | 0.4944 | 0.0018 | 0.0040 | 0.0100 | 0.0258 | 0.0759 | 0.1202 | 0.0937 | 0.1112 | 0.5575 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1152 | 223 | | 1691 | 12352 | 99.2 | 17.11 | 46.92 | 69.30 | 79 | 84 | 88 | 92 | 96 | 101 | 107 | 114 | 124 | 0.0508 | 627 | 1.190 | 91.98 | 34.23 | 1 | 0.1366 | 231 | 0.0065 | 7.72 | 5.324 | 0.3702 | 10134.8 | 1070000 | 116000000 | 12900000000 | 0.3875 | 0.2575 | 0.0008 | 0.0000 | 0.0040 | 0.0000 | 0.0127 | 0.0000 | 0.0343 | 0.0024 | 0.0741 | 0.0253 | 0.1076 | 0.0519 | 0.1139 | 0.0404 | 0.1777 | 0.0821 | 0.4749 | 0.7978 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0047 | 0.0000 | 0.0206 | 0.0018 | 0.0419 | 0.0231 | 0.0599 | 0.0420 | 0.0573 | 0.0213 | 0.0879 | 0.0390 | 0.7264 | 0.8729 | 0.0121 | 0.1176 | 0.0040 | 0.1765 | 0.0526 | 0.2353 | 0.0931 | 0.2941 | 0.1336 | 0.1176 | 0.1903 | 0.0588 | 0.1579 | 0.0000 | 0.1741 | 0.0000 | 0.1822 | 0.0000 | 0.0039 | 0.0065 | 0.0310 | 0.0233 | 0.0802 | 0.1125 | 0.1035 | 0.1475 | 0.4916 | 7 | 10 | 13 | 17 | 23 | 32 | 44 | 64 | 112 | 0.0318 | 9.40 | 4.580 | 0.5581 | 7003.8 | 2350000 | 1290000000 | 919000000000 | 0.6011 | 0.1309 | 0.0239 | 0.0061 | 0.0710 | 0.0163 | 0.1253 | 0.0476 | 0.1857 | 0.0850 | 0.1744 | 0.1282 | 0.1459 | 0.1473 | 0.1187 | 0.1486 | 0.1054 | 0.1514 | 0.0497 | 0.2694 | 0.0028 | 0.0028 | 0.0058 | 0.0052 | 0.0106 | 0.0099 | 0.0311 | 0.0268 | 0.0659 | 0.0579 | 0.0954 | 0.0806 | 0.0809 | 0.0798 | 0.1143 | 0.1059 | 0.5934 | 0.6311 | 0.0056 | 0.0063 | 0.0141 | 0.0117 | 0.0159 | 0.0184 | 0.0286 | 0.0284 | 0.0766 | 0.0755 | 0.1048 | 0.1172 | 0.0886 | 0.0893 | 0.1172 | 0.1247 | 0.5485 | 0.5286 | 0.0026 | 0.0105 | 0.0228 | 0.0324 | 0.0762 | 0.0964 | 0.0836 | 0.1155 | 0.5599 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1099 | 456 | | 4384 | 11255 | 330.4 | 82.17 | 122.23 | 126.09 | 224 | 258 | 283 | 305 | 326 | 347 | 372 | 400 | 446 | 0.0782 | 880 | 1.074 | 91.24 | 29.15 | 1 | 0.0527 | 231 | 0.0005 | 119.89 | 7.749 | 0.1150 | 115898.0 | 42900000 | 16600000000 | 6700000000000 | 0.4213 | 0.2264 | 0.0004 | 0.0003 | 0.0004 | 0.0000 | 0.0020 | 0.0008 | 0.0145 | 0.0036 | 0.0912 | 0.0281 | 0.1739 | 0.0521 | 0.1546 | 0.0521 | 0.1784 | 0.0727 | 0.3846 | 0.7904 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0002 | 0.0038 | 0.0012 | 0.0353 | 0.0176 | 0.0695 | 0.0312 | 0.0601 | 0.0279 | 0.0917 | 0.0391 | 0.7384 | 0.8827 | 0.0032 | 0.0063 | 0.0032 | 0.0158 | 0.0222 | 0.0095 | 0.0549 | 0.0886 | 0.1267 | 0.1203 | 0.1426 | 0.2089 | 0.0971 | 0.1582 | 0.1204 | 0.1487 | 0.4298 | 0.2437 | 0.0019 | 0.0024 | 0.0081 | 0.0276 | 0.0676 | 0.1257 | 0.0995 | 0.1185 | 0.5488 | 12 | 17 | 26 | 41 | 66 | 110 | 167 | 231 | 315 | 0.0244 | 16.78 | 5.456 | 0.4535 | 30835.4 | 10200000 | 3890000000 | 1660000000000 | 0.5357 | 0.1392 | 0.0679 | 0.0019 | 0.2575 | 0.0224 | 0.3413 | 0.1296 | 0.1487 | 0.2072 | 0.0978 | 0.2115 | 0.0459 | 0.1648 | 0.0279 | 0.1034 | 0.0120 | 0.0858 | 0.0010 | 0.0734 | 0.0000 | 0.0000 | 0.0013 | 0.0002 | 0.0025 | 0.0033 | 0.0197 | 0.0144 | 0.0659 | 0.0599 | 0.1055 | 0.0938 | 0.0848 | 0.0719 | 0.1153 | 0.1097 | 0.6050 | 0.6468 | 0.0013 | 0.0012 | 0.0024 | 0.0024 | 0.0109 | 0.0115 | 0.0270 | 0.0329 | 0.0840 | 0.0922 | 0.1224 | 0.1351 | 0.1038 | 0.1031 | 0.1234 | 0.1278 | 0.5248 | 0.4938 | 0.0000 | 0.0014 | 0.0058 | 0.0175 | 0.0782 | 0.1175 | 0.0896 | 0.1249 | 0.5651 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 425 | 828 | | 9686 | 14128 | 100.3 | 24.59 | 205.89 | 202.72 | 72 | 79 | 85 | 91 | 97 | 103 | 110 | 120 | 135 | 0.0773 | 1092 | 0.773 | 63.03 | 19.85 | 4 | 0.0184 | 178 | 0.0016 | 27.28 | 6.760 | 0.2225 | 10667.4 | 1200000 | 143000000 | 18000000000 | 0.4311 | 0.2206 | 0.0007 | 0.0000 | 0.0025 | 0.0002 | 0.0089 | 0.0003 | 0.0289 | 0.0048 | 0.0826 | 0.0210 | 0.1495 | 0.0494 | 0.1653 | 0.0539 | 0.1882 | 0.0764 | 0.3734 | 0.7940 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0000 | 0.0130 | 0.0021 | 0.0319 | 0.0109 | 0.0542 | 0.0231 | 0.0628 | 0.0163 | 0.0885 | 0.0251 | 0.7438 | 0.9226 | 0.0040 | 0.0078 | 0.0106 | 0.0142 | 0.0227 | 0.0492 | 0.0721 | 0.1410 | 0.1245 | 0.1643 | 0.1668 | 0.2018 | 0.1285 | 0.1294 | 0.1346 | 0.1345 | 0.3362 | 0.1578 | 0.0028 | 0.0044 | 0.0131 | 0.0331 | 0.0776 | 0.1130 | 0.1075 | 0.1367 | 0.5119 | 19 | 33 | 57 | 89 | 132 | 192 | 271 | 367 | 509 | 0.0106 | 35.88 | 6.248 | 0.3841 | 83484.1 | 45100000 | 28900000000 | 21200000000000 | 0.5547 | 0.1227 | 0.0456 | 0.0027 | 0.1805 | 0.0154 | 0.2495 | 0.1234 | 0.1651 | 0.1270 | 0.1294 | 0.1710 | 0.1041 | 0.1743 | 0.0548 | 0.1294 | 0.0370 | 0.1093 | 0.0339 | 0.1475 | 0.0005 | 0.0004 | 0.0013 | 0.0010 | 0.0037 | 0.0030 | 0.0122 | 0.0118 | 0.0659 | 0.0511 | 0.1064 | 0.0942 | 0.0799 | 0.0639 | 0.1109 | 0.0947 | 0.6192 | 0.6799 | 0.0004 | 0.0013 | 0.0022 | 0.0030 | 0.0061 | 0.0106 | 0.0230 | 0.0300 | 0.0848 | 0.0881 | 0.1339 | 0.1427 | 0.0916 | 0.1017 | 0.1258 | 0.1334 | 0.5322 | 0.4892 | 0.0002 | 0.0030 | 0.0037 | 0.0199 | 0.0732 | 0.1163 | 0.0904 | 0.1209 | 0.5723 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 632 | 107 | | 5692 | 8449 | 461.3 | 114.59 | 81.65 | 147.06 | 324 | 362 | 391 | 418 | 445 | 473 | 513 | 563 | 630 | 0.0921 | 778 | 1.004 | 71.59 | 22.36 | 1 | 0.0293 | 167 | 0.0009 | 39.64 | 7.251 | 0.1882 | 225883.0 | 117000000 | 63800000000 | 36400000000000 | 0.4330 | 0.2108 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0078 | 0.0014 | 0.0210 | 0.0041 | 0.0784 | 0.0255 | 0.1563 | 0.0518 | 0.1327 | 0.0450 | 0.1660 | 0.0713 | 0.4365 | 0.8009 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0000 | 0.0074 | 0.0007 | 0.0379 | 0.0141 | 0.0737 | 0.0297 | 0.0602 | 0.0251 | 0.0848 | 0.0373 | 0.7332 | 0.8931 | 0.0048 | 0.0043 | 0.0072 | 0.0043 | 0.0096 | 0.0215 | 0.0377 | 0.0667 | 0.0786 | 0.1419 | 0.1195 | 0.1699 | 0.0898 | 0.1548 | 0.0922 | 0.1462 | 0.5605 | 0.2903 | 0.0020 | 0.0075 | 0.0110 | 0.0272 | 0.0745 | 0.0926 | 0.0764 | 0.1068 | 0.6020 | 6 | 8 | 9 | 11 | 14 | 23 | 53 | 116 | 264 | 0.1415 | 20.12 | 4.010 | 0.6235 | 28288.5 | 14800000 | 9450000000 | 6870000000000 | 0.6511 | 0.0624 | 0.0586 | 0.0033 | 0.1302 | 0.0308 | 0.2256 | 0.1156 | 0.1757 | 0.1344 | 0.1952 | 0.1817 | 0.1106 | 0.1762 | 0.0521 | 0.1443 | 0.0282 | 0.1112 | 0.0239 | 0.1024 | 0.0009 | 0.0004 | 0.0035 | 0.0031 | 0.0035 | 0.0046 | 0.0173 | 0.0134 | 0.0658 | 0.0598 | 0.0879 | 0.0854 | 0.0602 | 0.0590 | 0.0974 | 0.0935 | 0.6635 | 0.6808 | 0.0016 | 0.0006 | 0.0005 | 0.0024 | 0.0043 | 0.0024 | 0.0173 | 0.0182 | 0.0758 | 0.0740 | 0.0963 | 0.1099 | 0.0568 | 0.0558 | 0.1034 | 0.1128 | 0.6439 | 0.6240 | 0.0014 | 0.0029 | 0.0043 | 0.0193 | 0.0696 | 0.0904 | 0.0541 | 0.1087 | 0.6491 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 849 | | 5669 | 11631 | 149.6 | 30.26 | 380.14 | 292.12 | 115 | 126 | 133 | 140 | 146 | 153 | 161 | 172 | 189 | 0.0978 | 1138 | 0.853 | 87.32 | 20.22 | 4 | 0.0376 | 213 | 0.0246 | 2.00 | 4.135 | 0.5882 | 23308.7 | 3780000 | 639000000 | 113000000000 | 0.4512 | 0.2143 | 0.0005 | 0.0000 | 0.0019 | 0.0004 | 0.0066 | 0.0006 | 0.0209 | 0.0047 | 0.0542 | 0.0190 | 0.1074 | 0.0594 | 0.1031 | 0.0456 | 0.1449 | 0.0760 | 0.5605 | 0.7945 | 0.0002 | 0.0000 | 0.0012 | 0.0002 | 0.0022 | 0.0005 | 0.0087 | 0.0041 | 0.0281 | 0.0148 | 0.0485 | 0.0422 | 0.0396 | 0.0185 | 0.0686 | 0.0351 | 0.8028 | 0.8846 | 0.0072 | 0.0165 | 0.0217 | 0.0535 | 0.0253 | 0.0535 | 0.0939 | 0.1934 | 0.1721 | 0.2058 | 0.1877 | 0.1934 | 0.1095 | 0.0864 | 0.1300 | 0.0947 | 0.2527 | 0.1029 | 0.0031 | 0.0043 | 0.0152 | 0.0390 | 0.0928 | 0.1383 | 0.1200 | 0.1380 | 0.4493 | 68 | 117 | 173 | 239 | 313 | 389 | 493 | 610 | 797 | 0.0026 | 36.91 | 6.778 | 0.2991 | 229829.0 | 180000000 | 166000000000 | 173000000000000 | 0.5041 | 0.1494 | 0.0174 | 0.0017 | 0.0886 | 0.0073 | 0.1781 | 0.0403 | 0.1658 | 0.0825 | 0.1856 | 0.1556 | 0.1451 | 0.1874 | 0.0933 | 0.1449 | 0.0612 | 0.1473 | 0.0650 | 0.2330 | 0.0002 | 0.0000 | 0.0023 | 0.0006 | 0.0058 | 0.0035 | 0.0167 | 0.0122 | 0.0657 | 0.0480 | 0.1189 | 0.0967 | 0.0796 | 0.0703 | 0.1194 | 0.1013 | 0.5913 | 0.6674 | 0.0015 | 0.0013 | 0.0036 | 0.0039 | 0.0103 | 0.0186 | 0.0328 | 0.0417 | 0.0904 | 0.1037 | 0.1420 | 0.1637 | 0.1030 | 0.1027 | 0.1258 | 0.1376 | 0.4904 | 0.4266 | 0.0006 | 0.0031 | 0.0121 | 0.0249 | 0.0804 | 0.1317 | 0.0936 | 0.1214 | 0.5321 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1223 | 452 | | 6155 | 9803 | 128.7 | 28.06 | 148.51 | 137.13 | 95 | 105 | 112 | 119 | 126 | 133 | 141 | 152 | 166 | 0.0870 | 853 | 0.535 | 195.17 | 41.62 | 2 | 0.0980 | 603 | 0.0012 | 37.11 | 6.972 | 0.1989 | 17339.8 | 2450000 | 361000000 | 55800000000 | 0.4378 | 0.2119 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0054 | 0.0000 | 0.0219 | 0.0026 | 0.0706 | 0.0184 | 0.1443 | 0.0426 | 0.1512 | 0.0447 | 0.1856 | 0.0693 | 0.4192 | 0.8224 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0022 | 0.0000 | 0.0078 | 0.0007 | 0.0301 | 0.0139 | 0.0603 | 0.0269 | 0.0630 | 0.0203 | 0.0920 | 0.0328 | 0.7436 | 0.9054 | 0.0055 | 0.0231 | 0.0156 | 0.0423 | 0.0294 | 0.1000 | 0.0725 | 0.1577 | 0.1330 | 0.1577 | 0.1982 | 0.1731 | 0.1330 | 0.1269 | 0.1450 | 0.0885 | 0.2679 | 0.1308 | 0.0021 | 0.0067 | 0.0102 | 0.0376 | 0.0709 | 0.1254 | 0.1180 | 0.1394 | 0.4898 | 14 | 24 | 55 | 81 | 109 | 144 | 187 | 247 | 346 | 0.0183 | 16.97 | 5.620 | 0.4458 | 40857.3 | 15200000 | 6830000000 | 3500000000000 | 0.6750 | 0.0565 | 0.0233 | 0.0013 | 0.1047 | 0.0122 | 0.2115 | 0.0411 | 0.1937 | 0.0746 | 0.1814 | 0.1677 | 0.1513 | 0.1982 | 0.0767 | 0.1700 | 0.0431 | 0.1519 | 0.0144 | 0.1831 | 0.0004 | 0.0005 | 0.0002 | 0.0013 | 0.0026 | 0.0023 | 0.0199 | 0.0116 | 0.0656 | 0.0497 | 0.1179 | 0.0886 | 0.0905 | 0.0744 | 0.1297 | 0.1150 | 0.5731 | 0.6565 | 0.0000 | 0.0012 | 0.0016 | 0.0051 | 0.0090 | 0.0086 | 0.0347 | 0.0451 | 0.1006 | 0.1221 | 0.1546 | 0.1495 | 0.1060 | 0.1197 | 0.1375 | 0.1436 | 0.4560 | 0.4050 | 0.0003 | 0.0016 | 0.0047 | 0.0229 | 0.0938 | 0.1286 | 0.0967 | 0.1442 | 0.5071 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1139 | 881 | | 6326 | 14317 | 189.9 | 47.31 | 165.02 | 129.26 | 138 | 151 | 161 | 171 | 182 | 193 | 206 | 224 | 252 | 0.0773 | 1106 | 1.024 | 100.80 | 38.29 | 1 | 0.0438 | 277 | 0.0012 | 42.09 | 7.012 | 0.1876 | 38280.7 | 8230000 | 1890000000 | 462000000000 | 0.4259 | 0.2291 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0057 | 0.0000 | 0.0234 | 0.0019 | 0.0776 | 0.0210 | 0.1558 | 0.0447 | 0.1631 | 0.0445 | 0.1831 | 0.0635 | 0.3895 | 0.8244 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0098 | 0.0003 | 0.0319 | 0.0121 | 0.0718 | 0.0241 | 0.0706 | 0.0168 | 0.0970 | 0.0254 | 0.7152 | 0.9213 | 0.0052 | 0.0064 | 0.0103 | 0.0107 | 0.0207 | 0.0258 | 0.0767 | 0.0794 | 0.1259 | 0.1803 | 0.1759 | 0.1674 | 0.1190 | 0.1180 | 0.1250 | 0.1545 | 0.3414 | 0.2575 | 0.0007 | 0.0055 | 0.0117 | 0.0371 | 0.0950 | 0.1273 | 0.1185 | 0.1383 | 0.4659 | 34 | 48 | 69 | 97 | 132 | 170 | 214 | 268 | 354 | 0.0028 | 59.79 | 6.896 | 0.2662 | 43937.1 | 15200000 | 6170000000 | 2820000000000 | 0.5199 | 0.1445 | 0.0243 | 0.0025 | 0.1004 | 0.0068 | 0.2160 | 0.0533 | 0.1831 | 0.1121 | 0.1711 | 0.1528 | 0.1263 | 0.1873 | 0.0814 | 0.1483 | 0.0675 | 0.1416 | 0.0300 | 0.1953 | 0.0008 | 0.0007 | 0.0008 | 0.0002 | 0.0040 | 0.0028 | 0.0205 | 0.0158 | 0.0656 | 0.0457 | 0.0960 | 0.0802 | 0.0795 | 0.0679 | 0.1224 | 0.0924 | 0.6103 | 0.6942 | 0.0013 | 0.0018 | 0.0055 | 0.0060 | 0.0103 | 0.0189 | 0.0352 | 0.0463 | 0.0967 | 0.1178 | 0.1415 | 0.1568 | 0.1118 | 0.1307 | 0.1417 | 0.1494 | 0.4561 | 0.3722 | 0.0007 | 0.0012 | 0.0066 | 0.0298 | 0.0752 | 0.1185 | 0.1015 | 0.1342 | 0.5323 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 534 | 923 | | 4850 | 8622 | 162.0 | 44.63 | 180.98 | 189.76 | 115 | 127 | 136 | 144 | 153 | 163 | 176 | 194 | 220 | 0.0923 | 796 | 1.107 | 100.01 | 36.69 | 1 | 0.0542 | 263 | 0.0016 | 35.56 | 6.803 | 0.2042 | 28220.0 | 5320000 | 1090000000 | 244000000000 | 0.4589 | 0.1995 | 0.0007 | 0.0000 | 0.0029 | 0.0005 | 0.0119 | 0.0016 | 0.0353 | 0.0018 | 0.0965 | 0.0224 | 0.1780 | 0.0576 | 0.1567 | 0.0576 | 0.1780 | 0.0908 | 0.3401 | 0.7676 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0024 | 0.0000 | 0.0113 | 0.0004 | 0.0464 | 0.0146 | 0.0848 | 0.0310 | 0.0754 | 0.0240 | 0.1095 | 0.0437 | 0.6690 | 0.8863 | 0.0021 | 0.0124 | 0.0095 | 0.0173 | 0.0148 | 0.0173 | 0.0674 | 0.0990 | 0.1349 | 0.1708 | 0.1802 | 0.1931 | 0.1117 | 0.0990 | 0.1454 | 0.1411 | 0.3340 | 0.2500 | 0.0025 | 0.0020 | 0.0129 | 0.0373 | 0.0821 | 0.1318 | 0.1035 | 0.1274 | 0.5005 | 14 | 24 | 41 | 71 | 110 | 159 | 230 | 325 | 469 | 0.0065 | 92.57 | 6.832 | 0.2972 | 68756.7 | 35000000 | 20900000000 | 13800000000000 | 0.4654 | 0.1787 | 0.0372 | 0.0015 | 0.1157 | 0.0126 | 0.2314 | 0.0576 | 0.2038 | 0.0919 | 0.1826 | 0.1859 | 0.1210 | 0.2273 | 0.0605 | 0.1485 | 0.0297 | 0.1348 | 0.0180 | 0.1399 | 0.0011 | 0.0005 | 0.0019 | 0.0018 | 0.0057 | 0.0016 | 0.0164 | 0.0127 | 0.0655 | 0.0540 | 0.0911 | 0.0881 | 0.0668 | 0.0623 | 0.0898 | 0.0865 | 0.6617 | 0.6924 | 0.0018 | 0.0000 | 0.0015 | 0.0081 | 0.0066 | 0.0098 | 0.0239 | 0.0242 | 0.0668 | 0.0752 | 0.1146 | 0.1134 | 0.0856 | 0.0935 | 0.1050 | 0.1143 | 0.5942 | 0.5616 | 0.0003 | 0.0028 | 0.0070 | 0.0215 | 0.0579 | 0.0958 | 0.0730 | 0.1078 | 0.6339 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 489 | 834 | | 12111 | 18609 | 541.6 | 118.52 | 168.67 | 182.80 | 399 | 441 | 476 | 505 | 532 | 559 | 589 | 628 | 690 | 0.0564 | 1049 | 1.226 | 127.68 | 55.00 | 1 | 0.0283 | 343 | 0.0010 | 25.57 | 7.191 | 0.2311 | 307350.0 | 183000000 | 114000000000 | 74500000000000 | 0.4223 | 0.2210 | 0.0002 | 0.0001 | 0.0011 | 0.0003 | 0.0035 | 0.0002 | 0.0121 | 0.0018 | 0.0351 | 0.0123 | 0.0639 | 0.0223 | 0.0770 | 0.0188 | 0.1064 | 0.0282 | 0.7006 | 0.9161 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0017 | 0.0002 | 0.0050 | 0.0010 | 0.0150 | 0.0084 | 0.0268 | 0.0140 | 0.0306 | 0.0093 | 0.0434 | 0.0135 | 0.8767 | 0.9536 | 0.0032 | 0.0045 | 0.0053 | 0.0061 | 0.0150 | 0.0151 | 0.0513 | 0.0363 | 0.0898 | 0.0802 | 0.1165 | 0.1104 | 0.1010 | 0.0726 | 0.1112 | 0.1104 | 0.5067 | 0.5643 | 0.0016 | 0.0023 | 0.0060 | 0.0213 | 0.0499 | 0.0789 | 0.0809 | 0.1040 | 0.6550 | 8 | 14 | 27 | 56 | 102 | 159 | 227 | 312 | 435 | 0.0253 | 65.01 | 6.264 | 0.3576 | 61863.3 | 30100000 | 17400000000 | 11500000000000 | 0.4777 | 0.1891 | 0.0835 | 0.0023 | 0.2306 | 0.0249 | 0.2838 | 0.1678 | 0.1513 | 0.1698 | 0.1153 | 0.1751 | 0.0782 | 0.1769 | 0.0402 | 0.1114 | 0.0146 | 0.0964 | 0.0026 | 0.0755 | 0.0004 | 0.0001 | 0.0000 | 0.0000 | 0.0005 | 0.0009 | 0.0147 | 0.0085 | 0.0655 | 0.0544 | 0.1197 | 0.0976 | 0.0848 | 0.0670 | 0.1186 | 0.1038 | 0.5959 | 0.6678 | 0.0000 | 0.0007 | 0.0011 | 0.0021 | 0.0057 | 0.0062 | 0.0239 | 0.0327 | 0.0959 | 0.1092 | 0.1534 | 0.1697 | 0.1026 | 0.1133 | 0.1390 | 0.1561 | 0.4782 | 0.4101 | 0.0001 | 0.0000 | 0.0024 | 0.0177 | 0.0832 | 0.1361 | 0.0944 | 0.1341 | 0.5320 | ||
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 430 | | 9439 | 30387 | 187.6 | 49.18 | 85.43 | 137.20 | 127 | 150 | 163 | 176 | 187 | 199 | 211 | 226 | 249 | 0.0448 | 1360 | 0.978 | 133.06 | 44.05 | 3 | 0.0366 | 345 | 0.0011 | 36.27 | 7.174 | 0.1963 | 37625.0 | 7970000 | 1770000000 | 413000000000 | 0.4260 | 0.2189 | 0.0002 | 0.0000 | 0.0009 | 0.0001 | 0.0043 | 0.0007 | 0.0199 | 0.0027 | 0.0634 | 0.0169 | 0.1233 | 0.0399 | 0.1423 | 0.0401 | 0.1734 | 0.0580 | 0.4723 | 0.8415 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0072 | 0.0010 | 0.0225 | 0.0102 | 0.0434 | 0.0235 | 0.0516 | 0.0149 | 0.0628 | 0.0250 | 0.8102 | 0.9254 | 0.0063 | 0.0066 | 0.0083 | 0.0115 | 0.0276 | 0.0508 | 0.0683 | 0.0869 | 0.1017 | 0.1328 | 0.1424 | 0.1410 | 0.1226 | 0.1016 | 0.1346 | 0.1279 | 0.3881 | 0.3410 | 0.0009 | 0.0032 | 0.0071 | 0.0234 | 0.0626 | 0.0939 | 0.0934 | 0.1316 | 0.5841 | 10 | 12 | 14 | 16 | 20 | 29 | 62 | 140 | 267 | 0.1579 | 16.30 | 3.924 | 0.6407 | 26120.0 | 12600000 | 7750000000 | 5660000000000 | 0.5727 | 0.1271 | 0.1171 | 0.0076 | 0.2705 | 0.0420 | 0.2342 | 0.2186 | 0.1164 | 0.1757 | 0.1023 | 0.1567 | 0.0686 | 0.1384 | 0.0444 | 0.0856 | 0.0316 | 0.0752 | 0.0148 | 0.1002 | 0.0003 | 0.0005 | 0.0015 | 0.0008 | 0.0032 | 0.0031 | 0.0147 | 0.0133 | 0.0655 | 0.0528 | 0.0960 | 0.0906 | 0.0648 | 0.0549 | 0.0997 | 0.0876 | 0.6543 | 0.6964 | 0.0001 | 0.0004 | 0.0007 | 0.0004 | 0.0029 | 0.0039 | 0.0241 | 0.0258 | 0.0759 | 0.0823 | 0.1193 | 0.1295 | 0.0787 | 0.0827 | 0.1092 | 0.1138 | 0.5892 | 0.5612 | 0.0004 | 0.0010 | 0.0023 | 0.0194 | 0.0694 | 0.1084 | 0.0725 | 0.1053 | 0.6214 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1195 | 448 | | 4077 | 9038 | 310.9 | 53.86 | 181.75 | 300.58 | 243 | 263 | 279 | 292 | 306 | 323 | 341 | 360 | 384 | 0.0823 | 744 | 0.923 | 64.47 | 17.49 | 1 | 0.0373 | 152 | 0.0015 | 24.49 | 6.739 | 0.2284 | 99584.3 | 32800000 | 11100000000 | 3850000000000 | 0.4223 | 0.2256 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0002 | 0.0166 | 0.0005 | 0.0445 | 0.0156 | 0.0831 | 0.0297 | 0.0950 | 0.0225 | 0.1292 | 0.0312 | 0.6276 | 0.9002 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0014 | 0.0002 | 0.0081 | 0.0005 | 0.0209 | 0.0152 | 0.0345 | 0.0258 | 0.0376 | 0.0142 | 0.0585 | 0.0219 | 0.8387 | 0.9222 | 0.0069 | 0.0000 | 0.0086 | 0.0000 | 0.0293 | 0.0000 | 0.0810 | 0.0000 | 0.1207 | 0.0000 | 0.1828 | 0.0000 | 0.1293 | 0.0000 | 0.1483 | 0.0000 | 0.2931 | 0.0000 | 0.0026 | 0.0021 | 0.0057 | 0.0188 | 0.0490 | 0.0834 | 0.0870 | 0.1021 | 0.6493 | 19 | 24 | 31 | 45 | 71 | 99 | 135 | 242 | 489 | 0.0344 | 32.85 | 5.199 | 0.5254 | 123371.0 | 146000000 | 217000000000 | 363000000000000 | 0.4937 | 0.1466 | 0.0515 | 0.0058 | 0.1530 | 0.0187 | 0.2641 | 0.0515 | 0.1578 | 0.1120 | 0.1401 | 0.1552 | 0.1014 | 0.1964 | 0.0354 | 0.1365 | 0.0290 | 0.1223 | 0.0676 | 0.2015 | 0.0012 | 0.0021 | 0.0063 | 0.0021 | 0.0067 | 0.0027 | 0.0185 | 0.0209 | 0.0653 | 0.0581 | 0.1034 | 0.0877 | 0.0594 | 0.0714 | 0.0975 | 0.1025 | 0.6418 | 0.6525 | 0.0005 | 0.0000 | 0.0010 | 0.0023 | 0.0031 | 0.0029 | 0.0166 | 0.0165 | 0.0786 | 0.0764 | 0.0994 | 0.1107 | 0.0708 | 0.0696 | 0.1124 | 0.1095 | 0.6176 | 0.6121 | 0.0000 | 0.0014 | 0.0023 | 0.0148 | 0.0696 | 0.1035 | 0.0650 | 0.1072 | 0.6362 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 387 | 433 | | 5231 | 10050 | 128.6 | 29.95 | 253.02 | 164.61 | 95 | 106 | 112 | 118 | 124 | 131 | 139 | 149 | 167 | 0.0766 | 770 | 1.025 | 94.58 | 21.95 | 1 | 0.0417 | 218 | 0.0027 | 19.06 | 6.270 | 0.2625 | 17434.3 | 2500000 | 381000000 | 61800000000 | 0.4642 | 0.1924 | 0.0009 | 0.0000 | 0.0012 | 0.0004 | 0.0063 | 0.0008 | 0.0155 | 0.0006 | 0.0748 | 0.0204 | 0.1327 | 0.0433 | 0.1376 | 0.0474 | 0.1804 | 0.0775 | 0.4506 | 0.8094 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0004 | 0.0058 | 0.0004 | 0.0353 | 0.0138 | 0.0679 | 0.0272 | 0.0616 | 0.0216 | 0.0981 | 0.0325 | 0.7281 | 0.9042 | 0.0035 | 0.0236 | 0.0058 | 0.0505 | 0.0256 | 0.0337 | 0.0816 | 0.0741 | 0.1457 | 0.1886 | 0.1620 | 0.1818 | 0.1550 | 0.0976 | 0.1352 | 0.1515 | 0.2855 | 0.1987 | 0.0022 | 0.0065 | 0.0113 | 0.0427 | 0.0946 | 0.1325 | 0.1176 | 0.1451 | 0.4475 | 60 | 102 | 143 | 183 | 224 | 272 | 324 | 390 | 488 | 0.0010 | 93.19 | 7.522 | 0.1835 | 91109.9 | 40300000 | 20400000000 | 11500000000000 | 0.4846 | 0.1715 | 0.0159 | 0.0002 | 0.0785 | 0.0058 | 0.2247 | 0.0267 | 0.1565 | 0.0755 | 0.1770 | 0.1506 | 0.1499 | 0.1952 | 0.0887 | 0.1576 | 0.0612 | 0.1601 | 0.0476 | 0.2282 | 0.0009 | 0.0000 | 0.0011 | 0.0015 | 0.0050 | 0.0019 | 0.0179 | 0.0119 | 0.0651 | 0.0482 | 0.1005 | 0.0787 | 0.0938 | 0.0705 | 0.1206 | 0.1004 | 0.5951 | 0.6868 | 0.0012 | 0.0036 | 0.0041 | 0.0052 | 0.0106 | 0.0203 | 0.0361 | 0.0584 | 0.0993 | 0.1247 | 0.1704 | 0.1918 | 0.1202 | 0.1275 | 0.1539 | 0.1485 | 0.4042 | 0.3201 | 0.0002 | 0.0034 | 0.0073 | 0.0241 | 0.0768 | 0.1375 | 0.1128 | 0.1355 | 0.5024 |
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 559 | | 1919 | 9291 | 297.6 | 53.29 | 250.19 | 260.24 | 215 | 254 | 277 | 295 | 308 | 321 | 332 | 343 | 357 | 0.0677 | 629 | 1.003 | 87.82 | 29.21 | 1 | 0.1178 | 226 | 0.0022 | 14.65 | 6.307 | 0.2647 | 91416.6 | 28800000 | 9250000000 | 3020000000000 | 0.3763 | 0.2593 | 0.0007 | 0.0005 | 0.0007 | 0.0000 | 0.0021 | 0.0005 | 0.0084 | 0.0011 | 0.0439 | 0.0183 | 0.0927 | 0.0458 | 0.0836 | 0.0188 | 0.1157 | 0.0285 | 0.6523 | 0.8864 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0012 | 0.0011 | 0.0265 | 0.0183 | 0.0468 | 0.0458 | 0.0302 | 0.0188 | 0.0406 | 0.0285 | 0.8548 | 0.8864 | 0.0105 | 0.0000 | 0.0000 | 0.0000 | 0.1000 | 0.0000 | 0.1263 | 0.0000 | 0.1842 | 0.0000 | 0.1842 | 0.0000 | 0.1421 | 0.0000 | 0.1421 | 0.0000 | 0.1105 | 0.0000 | 0.0000 | 0.0009 | 0.0036 | 0.0217 | 0.0407 | 0.0724 | 0.0733 | 0.1005 | 0.6869 | 21 | 33 | 58 | 95 | 149 | 231 | 329 | 452 | 626 | 0.0131 | 45.83 | 6.311 | 0.3810 | 130308.0 | 91600000 | 76700000000 | 72600000000000 | 0.6100 | 0.0919 | 0.0351 | 0.0025 | 0.1174 | 0.0114 | 0.2999 | 0.0602 | 0.1555 | 0.1210 | 0.1525 | 0.1916 | 0.1254 | 0.2020 | 0.0582 | 0.1432 | 0.0381 | 0.1249 | 0.0181 | 0.1432 | 0.0000 | 0.0000 | 0.0007 | 0.0006 | 0.0030 | 0.0017 | 0.0128 | 0.0101 | 0.0650 | 0.0509 | 0.0904 | 0.0798 | 0.0623 | 0.0612 | 0.1067 | 0.0878 | 0.6591 | 0.7078 | 0.0000 | 0.0004 | 0.0020 | 0.0011 | 0.0059 | 0.0061 | 0.0203 | 0.0318 | 0.0764 | 0.0842 | 0.1147 | 0.1248 | 0.0869 | 0.1083 | 0.1275 | 0.1348 | 0.5664 | 0.5084 | 0.0003 | 0.0011 | 0.0046 | 0.0154 | 0.0733 | 0.0984 | 0.0821 | 0.1146 | 0.6102 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 674 | 423 | | 2494 | 12270 | 100.8 | 25.07 | 240.02 | 220.97 | 70 | 79 | 87 | 94 | 100 | 105 | 112 | 120 | 134 | 0.0824 | 1011 | 0.313 | 186.85 | 42.64 | 3 | 0.3091 | 771 | 0.0033 | 14.33 | 5.992 | 0.3037 | 10783.5 | 1220000 | 145000000 | 18200000000 | 0.4342 | 0.2159 | 0.0007 | 0.0000 | 0.0034 | 0.0000 | 0.0189 | 0.0009 | 0.0444 | 0.0076 | 0.1098 | 0.0438 | 0.1825 | 0.0795 | 0.1589 | 0.0831 | 0.1845 | 0.1273 | 0.2970 | 0.6577 | 0.0005 | 0.0000 | 0.0015 | 0.0000 | 0.0056 | 0.0004 | 0.0153 | 0.0054 | 0.0490 | 0.0321 | 0.0842 | 0.0534 | 0.0745 | 0.0434 | 0.0990 | 0.0671 | 0.6704 | 0.7982 | 0.0042 | 0.0062 | 0.0253 | 0.0186 | 0.0547 | 0.1056 | 0.0674 | 0.1801 | 0.1558 | 0.1988 | 0.1853 | 0.1801 | 0.1137 | 0.1242 | 0.1726 | 0.1056 | 0.2211 | 0.0807 | 0.0025 | 0.0050 | 0.0091 | 0.0380 | 0.0809 | 0.1353 | 0.1089 | 0.1601 | 0.4604 | 20 | 40 | 82 | 132 | 185 | 240 | 304 | 392 | 551 | 0.0090 | 45.80 | 6.615 | 0.3329 | 106431.0 | 63700000 | 46200000000 | 38100000000000 | 0.5619 | 0.1212 | 0.0208 | 0.0008 | 0.1223 | 0.0067 | 0.2152 | 0.0569 | 0.1437 | 0.0937 | 0.1675 | 0.1632 | 0.1477 | 0.2010 | 0.0898 | 0.1402 | 0.0589 | 0.1320 | 0.0340 | 0.2056 | 0.0003 | 0.0000 | 0.0013 | 0.0004 | 0.0035 | 0.0018 | 0.0145 | 0.0100 | 0.0650 | 0.0520 | 0.1181 | 0.0946 | 0.0828 | 0.0744 | 0.1196 | 0.1048 | 0.5949 | 0.6619 | 0.0007 | 0.0025 | 0.0030 | 0.0053 | 0.0117 | 0.0171 | 0.0319 | 0.0421 | 0.0986 | 0.1075 | 0.1463 | 0.1430 | 0.1003 | 0.0888 | 0.1232 | 0.1174 | 0.4843 | 0.4763 | 0.0010 | 0.0010 | 0.0057 | 0.0267 | 0.0786 | 0.1316 | 0.0970 | 0.1210 | 0.5374 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 608 | 285 | | 12711 | 40214 | 295.5 | 67.78 | 143.73 | 163.15 | 209 | 239 | 260 | 277 | 293 | 309 | 328 | 350 | 384 | 0.0353 | 1418 | 1.016 | 119.62 | 46.69 | 2 | 0.0271 | 344 | 0.0013 | 26.32 | 6.921 | 0.2277 | 91894.8 | 30000000 | 10200000000 | 3620000000000 | 0.4370 | 0.2187 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0006 | 0.0194 | 0.0020 | 0.0643 | 0.0160 | 0.1388 | 0.0422 | 0.1306 | 0.0429 | 0.1606 | 0.0610 | 0.4809 | 0.8354 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0053 | 0.0011 | 0.0274 | 0.0105 | 0.0590 | 0.0245 | 0.0510 | 0.0194 | 0.0701 | 0.0291 | 0.7861 | 0.9154 | 0.0071 | 0.0128 | 0.0075 | 0.0192 | 0.0179 | 0.0417 | 0.0613 | 0.1330 | 0.1289 | 0.1875 | 0.1811 | 0.2051 | 0.1097 | 0.0865 | 0.1506 | 0.1330 | 0.3358 | 0.1811 | 0.0008 | 0.0024 | 0.0064 | 0.0265 | 0.0750 | 0.1260 | 0.1010 | 0.1299 | 0.5321 | 11 | 17 | 28 | 49 | 80 | 122 | 178 | 254 | 371 | 0.0435 | 17.85 | 5.232 | 0.4864 | 47276.4 | 22300000 | 13100000000 | 8910000000000 | 0.4347 | 0.1843 | 0.0559 | 0.0013 | 0.1725 | 0.0173 | 0.2681 | 0.1183 | 0.1475 | 0.1465 | 0.1431 | 0.1771 | 0.0944 | 0.1809 | 0.0533 | 0.1241 | 0.0376 | 0.1058 | 0.0276 | 0.1288 | 0.0001 | 0.0001 | 0.0004 | 0.0006 | 0.0019 | 0.0015 | 0.0116 | 0.0097 | 0.0649 | 0.0509 | 0.1109 | 0.0898 | 0.0752 | 0.0672 | 0.1098 | 0.0956 | 0.6253 | 0.6846 | 0.0006 | 0.0007 | 0.0011 | 0.0013 | 0.0036 | 0.0075 | 0.0213 | 0.0276 | 0.0840 | 0.0988 | 0.1417 | 0.1531 | 0.0910 | 0.0952 | 0.1254 | 0.1330 | 0.5313 | 0.4828 | 0.0003 | 0.0013 | 0.0032 | 0.0164 | 0.0787 | 0.1225 | 0.0861 | 0.1208 | 0.5707 |