High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)

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Cell SM Name Small Mol Concentration Small Mol Conc Unit Other Reagent 1 Name Other Reagent 1 Detection Channel Other Reagent 2 Name Other Reagent 2 Detection Channel Row Column Field X-coordinate Y-coordinate Image Nuclear area (pixels) Cytoplasm area (pixels) Nuclear intensity (AU) Std Dev of nuclear intensity (AU) Cytoplasm intensity (AU) Std Dev of cytoplasm intensity (AU) 10% quantile of nuclear intensity (AU) 20% quantile of nuclear intensity (AU) 30% quantile of nuclear intensity (AU) 40% quantile of nuclear intensity (AU) 50% quantile of nuclear intensity (AU) 60% quantile of nuclear intensity (AU) 70% quantile of nuclear intensity (AU) 80% quantile of nuclear intensity (AU) 90% quantile of nuclear intensity (AU) Ratio of cytoplasm perimeter to area Cytoplasm perimeter (pixels) Nuclear roundness Nuclear length (pixels) Nuclear halfwidth (pixels) Number of nuclei Ratio of nuclear perimeter to area Nuclear perimeter (pixels) Nuclear Haralick ASM Nuclear Haralick contrast Nuclear Haralick entropy Nuclear Haralick IDM Nuclear Haralick moment 2 Nuclear Haralick moment 3 Nuclear Haralick moment 4 Nuclear Haralick moment 5 Nuclear radial moment (border) Nuclear radial moment (center) Nuclear Threshold Adj Stat 1 (Threshold: 0.2) Nuclear Threshold Adj Stat 1 (Threshold: 0.4) Nuclear Threshold Adj Stat 2 (Threshold: 0.2) Nuclear Threshold Adj Stat 2 (Threshold: 0.4) Nuclear Threshold Adj Stat 3 (Threshold: 0.2) Nuclear Threshold Adj Stat 3 (Threshold: 0.4) Nuclear Threshold Adj Stat 4 (Threshold: 0.2) Nuclear Threshold Adj Stat 4 (Threshold: 0.4) Nuclear Threshold Adj Stat 5 (Threshold: 0.2) Nuclear Threshold Adj Stat 5 (Threshold: 0.4) Nuclear Threshold Adj Stat 6 (Threshold: 0.2) Nuclear Threshold Adj Stat 6 (Threshold: 0.4) Nuclear Threshold Adj Stat 7 (Threshold: 0.2) Nuclear Threshold Adj Stat 7 (Threshold: 0.4) Nuclear Threshold Adj Stat 8 (Threshold: 0.2) Nuclear Threshold Adj Stat 8 (Threshold: 0.4) Nuclear Threshold Adj Stat 9 (Threshold: 0.2) Nuclear Threshold Adj Stat 9 (Threshold: 0.4) Nuclear Threshold Adj Stat 10 (Threshold: 0.2) Nuclear Threshold Adj Stat 10 (Threshold: 0.4) Nuclear Threshold Adj Stat 11 (Threshold: 0.2) Nuclear Threshold Adj Stat 11 (Threshold: 0.4) Nuclear Threshold Adj Stat 12 (Threshold: 0.2) Nuclear Threshold Adj Stat 12 (Threshold: 0.4) Nuclear Threshold Adj Stat 13 (Threshold: 0.2) Nuclear Threshold Adj Stat 13 (Threshold: 0.4) Nuclear Threshold Adj Stat 14 (Threshold: 0.2) Nuclear Threshold Adj Stat 14 (Threshold: 0.4) Nuclear Threshold Adj Stat 15 (Threshold: 0.2) Nuclear Threshold Adj Stat 15 (Threshold: 0.4) Nuclear Threshold Adj Stat 16 (Threshold: 0.2) Nuclear Threshold Adj Stat 16 (Threshold: 0.4) Nuclear Threshold Adj Stat 17 (Threshold: 0.2) Nuclear Threshold Adj Stat 17 (Threshold: 0.4) Nuclear Threshold Adj Stat 18 (Threshold: 0.2) Nuclear Threshold Adj Stat 18 (Threshold: 0.4) Nuclear Threshold Adj Stat 19 (Threshold: 0.2) Nuclear Threshold Adj Stat 19 (Threshold: 0.4) Nuclear Threshold Adj Stat 20 (Threshold: 0.2) Nuclear Threshold Adj Stat 20 (Threshold: 0.4) Nuclear Threshold Adj Stat 21 (Threshold: 0.2) Nuclear Threshold Adj Stat 21 (Threshold: 0.4) Nuclear Threshold Adj Stat 22 (Threshold: 0.2) Nuclear Threshold Adj Stat 22 (Threshold: 0.4) Nuclear Threshold Adj Stat 23 (Threshold: 0.2) Nuclear Threshold Adj Stat 23 (Threshold: 0.4) Nuclear Threshold Adj Stat 24 (Threshold: 0.2) Nuclear Threshold Adj Stat 24 (Threshold: 0.4) Nuclear Threshold Adj Stat 25 (Threshold: 0.2) Nuclear Threshold Adj Stat 25 (Threshold: 0.4) Nuclear Threshold Adj Stat 26 (Threshold: 0.2) Nuclear Threshold Adj Stat 26 (Threshold: 0.4) Nuclear Threshold Adj Stat 27 (Threshold: 0.2) Nuclear Threshold Adj Stat 27 (Threshold: 0.4) Nuclear Threshold Adj Stat 28 Nuclear Threshold Adj Stat 29 Nuclear Threshold Adj Stat 30 Nuclear Threshold Adj Stat 31 Nuclear Threshold Adj Stat 32 Nuclear Threshold Adj Stat 33 Nuclear Threshold Adj Stat 34 Nuclear Threshold Adj Stat 35 Nuclear Threshold Adj Stat 36 10% quantile of cytoplasm intensity (AU) 20% quantile of cytoplasm intensity (AU) 30% quantile of cytoplasm intensity (AU) 40% quantile of cytoplasm intensity (AU) 50% quantile of cytoplasm intensity (AU) 60% quantile of cytoplasm intensity (AU) 70% quantile of cytoplasm intensity (AU) 80% quantile of cytoplasm intensity (AU) 90% quantile of cytoplasm intensity (AU) Cytoplasmic Haralick ASM Cytoplasmic Haralick contrast Cytoplasmic Haralick entropy Cytoplasmic Haralick IDM Cytoplasmic Haralick moment 2 Cytoplasmic Haralick moment 3 Cytoplasmic Haralick moment 4 Cytoplasmic Haralick moment 5 Cytoplasmic radial moment (border) Cytoplasmic radial moment (center) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) Cytoplasmic Threshold Adj Stat 28 Cytoplasmic Threshold Adj Stat 29 Cytoplasmic Threshold Adj Stat 30 Cytoplasmic Threshold Adj Stat 31 Cytoplasmic Threshold Adj Stat 32 Cytoplasmic Threshold Adj Stat 33 Cytoplasmic Threshold Adj Stat 34 Cytoplasmic Threshold Adj Stat 35 Cytoplasmic Threshold Adj Stat 36
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 568 142 image if available 3390 3676 488.2 76.89 55.99 95.47 384 420 448 473 493 513 533 556 587 0.1317 484 0.859 109.18 23.32 5 0.0752 255 0.0012 41.51 6.959 0.2091 244289.0
125000000
65200000000
34600000000000
0.4456 0.2022 0.0000 0.0000 0.0000 0.0000 0.0019 0.0000 0.0133 0.0009 0.0451 0.0139 0.0863 0.0237 0.0833 0.0160 0.1064 0.0261 0.6638 0.9194 0.0000 0.0000 0.0000 0.0000 0.0003 0.0000 0.0050 0.0009 0.0220 0.0139 0.0441 0.0237 0.0414 0.0154 0.0588 0.0231 0.8284 0.9230 0.0028 0.0000 0.0113 1.0000 0.0395 0.0000 0.1073 0.0000 0.1638 0.0000 0.2147 0.0000 0.1243 0.0000 0.1356 0.0000 0.2006 0.0000 0.0006 0.0017 0.0045 0.0195 0.0658 0.1155 0.1016 0.1267 0.5642 9 11 12 14 17 20 25 75 169 0.1554 6.68 3.147 0.7267 12247.2
4240000
1770000000
834000000000
0.4752 0.1492 0.0192 0.0284 0.0769 0.0355 0.1731 0.1277 0.3462 0.1489 0.1346 0.1915 0.1346 0.1773 0.1154 0.1206 0.0000 0.0709 0.0000 0.0993 0.0000 0.0046 0.0025 0.0058 0.0012 0.0116 0.0037 0.0127 0.0160 0.0197 0.0197 0.0313 0.0271 0.0174 0.0406 0.0440 0.8892 0.8530 0.0000 0.0000 0.0000 0.0000 0.0026 0.0028 0.0039 0.0083 0.0211 0.0221 0.0316 0.0456 0.0395 0.0415 0.0684 0.0692 0.8329 0.8105 0.0000 0.0000 0.0013 0.0038 0.0189 0.0215 0.0278 0.0556 0.8712
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 395 643 image if available 5110 12647 411.8 82.88 98.24 223.44 296 332 362 387 413 442 469 492 516 0.0659 833 1.130 86.12 29.43 1 0.0421 215 0.0017 11.85 6.634 0.3156 176415.0
78200000
35700000000
16700000000000
0.4107 0.2254 0.0009 0.0000 0.0028 0.0000 0.0066 0.0000 0.0133 0.0006 0.0344 0.0142 0.0667 0.0259 0.0689 0.0150 0.0910 0.0273 0.7153 0.9170 0.0005 0.0000 0.0010 0.0000 0.0027 0.0000 0.0046 0.0006 0.0126 0.0131 0.0239 0.0224 0.0220 0.0115 0.0305 0.0206 0.9023 0.9318 0.0041 0.0000 0.0072 0.1290 0.0103 0.1935 0.0351 0.1290 0.0784 0.2258 0.0991 0.2258 0.0877 0.0645 0.1290 0.0323 0.5490 0.0000 0.0004 0.0043 0.0031 0.0105 0.0233 0.0361 0.0415 0.0562 0.8247 7 8 10 11 13 16 30 87 318 0.2398 18.28 3.252 0.6811 59570.0
56500000
65600000000
86800000000000
0.3448 0.2408 0.0274 0.0023 0.1471 0.0150 0.2893 0.0495 0.1845 0.1164 0.1621 0.2085 0.0998 0.2385 0.0299 0.1336 0.0324 0.1083 0.0274 0.1279 0.0000 0.0007 0.0004 0.0007 0.0015 0.0020 0.0091 0.0078 0.0380 0.0346 0.0673 0.0620 0.0395 0.0400 0.0589 0.0491 0.7852 0.8032 0.0009 0.0005 0.0040 0.0010 0.0040 0.0024 0.0094 0.0086 0.0395 0.0427 0.0686 0.0734 0.0413 0.0504 0.0659 0.0705 0.7663 0.7505 0.0004 0.0013 0.0042 0.0129 0.0400 0.0642 0.0396 0.0554 0.7821
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 461 123 image if available 3257 6809 514.7 105.53 61.25 124.20 368 433 474 500 525 551 579 608 638 0.0824 561 0.766 87.00 16.03 3 0.0620 202 0.0010 52.75 7.148 0.1825 276060.0
153000000
86800000000
50400000000000
0.4286 0.2196 0.0000 0.0000 0.0014 0.0000 0.0068 0.0000 0.0140 0.0013 0.0512 0.0198 0.0978 0.0406 0.0965 0.0227 0.1277 0.0373 0.6046 0.8782 0.0000 0.0000 0.0000 0.0000 0.0004 0.0000 0.0029 0.0013 0.0220 0.0197 0.0447 0.0384 0.0293 0.0184 0.0411 0.0288 0.8596 0.8934 0.0077 0.1333 0.0173 0.1333 0.0288 0.0667 0.0865 0.1333 0.1404 0.2667 0.1442 0.1333 0.1231 0.0000 0.1654 0.1333 0.2865 0.0000 0.0011 0.0023 0.0079 0.0186 0.0514 0.0814 0.0729 0.1040 0.6605 7 9 11 12 14 19 31 56 175 0.1883 7.43 3.201 0.7374 19174.6
10600000
7360000000
5780000000000
0.4921 0.1647 0.0338 0.0142 0.0549 0.0252 0.0717 0.0377 0.0928 0.0660 0.1392 0.0849 0.1814 0.1289 0.2363 0.1321 0.1097 0.1525 0.0802 0.3585 0.0034 0.0045 0.0048 0.0078 0.0034 0.0111 0.0109 0.0167 0.0212 0.0279 0.0519 0.0507 0.0355 0.0423 0.0444 0.0591 0.8245 0.7799 0.0000 0.0000 0.0008 0.0000 0.0016 0.0000 0.0073 0.0078 0.0334 0.0336 0.0465 0.0509 0.0302 0.0259 0.0522 0.0578 0.8280 0.8240 0.0008 0.0008 0.0046 0.0106 0.0236 0.0540 0.0274 0.0547 0.8237
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 815 163 image if available 2938 15825 562.8 165.66 10.78 7.31 288 401 494 571 620 652 677 696 723 0.0577 913 0.956 43.93 14.04 1 0.0388 114 0.0035 13.77 6.195 0.3459 344227.0
221000000
147000000000
100000000000000
0.3768 0.2427 0.0046 0.0000 0.0069 0.0000 0.0069 0.0004 0.0299 0.0021 0.0851 0.0207 0.1219 0.0435 0.0913 0.0236 0.1296 0.0464 0.5238 0.8632 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0023 0.0016 0.0213 0.0175 0.0344 0.0358 0.0222 0.0179 0.0376 0.0350 0.8822 0.8921 0.0022 0.0000 0.0078 0.0100 0.0111 0.0200 0.0388 0.0200 0.0543 0.0800 0.1008 0.1300 0.1008 0.0700 0.1274 0.1400 0.5570 0.5300 0.0006 0.0000 0.0000 0.0050 0.0233 0.0417 0.0267 0.0389 0.8639 5 6 7 8 9 10 11 12 19 0.2362 0.38 1.298 0.6613 169.5
3950.18
122472
4500000
0.5976 0.1040 0.0323 0.0020 0.0756 0.0106 0.1133 0.0336 0.1438 0.0726 0.1811 0.1062 0.1857 0.1514 0.1597 0.2027 0.0873 0.2334 0.0211 0.1876 0.0202 0.0012 0.0489 0.0067 0.0693 0.0257 0.0868 0.0568 0.1051 0.0848 0.1135 0.1256 0.1228 0.1539 0.1364 0.1840 0.2969 0.3614 0.0929 0.0470 0.0631 0.0212 0.0423 0.0131 0.0317 0.0217 0.0372 0.0359 0.0533 0.0606 0.0451 0.0526 0.0776 0.0773 0.5568 0.6705 0.0675 0.0951 0.0928 0.0982 0.0980 0.0940 0.0648 0.0545 0.3351
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1179 272 image if available 484 417 15.1 6.24 5.44 2.42 10 11 12 12 13 15 16 18 23 0.4964 207 0.834 37.74 12.04 0 0.2397 116 0.0096 14.01 4.972 0.3037 265.5
5621.95
142364
4170000
0.3690 0.2458 0.0041 0.0000 0.0207 0.0000 0.0664 0.0000 0.1660 0.0426 0.1618 0.0727 0.1826 0.1053 0.1826 0.1328 0.1369 0.1529 0.0788 0.4937 0.0000 0.0000 0.0146 0.0000 0.0292 0.0000 0.0437 0.0325 0.0787 0.0433 0.1108 0.0584 0.1224 0.0714 0.1866 0.0952 0.4140 0.6991 0.0392 0.0000 0.0392 0.0476 0.0686 0.0635 0.0490 0.0794 0.0784 0.1429 0.1961 0.1111 0.0980 0.1111 0.1275 0.1111 0.3039 0.3333 0.0051 0.0256 0.0718 0.0821 0.1026 0.1333 0.1385 0.1179 0.3231 3 3 4 5 5 7 7 7 9 0.0300 14.00 3.917 0.2952 35.4
257.772
2032.6
17052.4
0.3900 0.1941 0.1136 0.0290 0.2652 0.0773 0.2803 0.2174 0.1667 0.2560 0.0909 0.2029 0.0530 0.1353 0.0303 0.0628 0.0000 0.0145 0.0000 0.0048 0.0032 0.0000 0.0194 0.0079 0.0809 0.0159 0.1748 0.0714 0.2201 0.1720 0.2071 0.1746 0.1909 0.2302 0.0906 0.2169 0.0129 0.1111 0.0734 0.0760 0.1751 0.2047 0.3277 0.3392 0.2260 0.2222 0.1186 0.0877 0.0395 0.0292 0.0395 0.0409 0.0000 0.0000 0.0000 0.0000 0.0072 0.0433 0.1300 0.2202 0.2238 0.1805 0.1336 0.0542 0.0072
MCF 10A A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 703 330 image if available 1517 7267 260.9 69.91 59.78 117.99 178 191 206 227 248 274 304 331 369 0.0860 625 1.115 107.79 38.05 1 0.1793 272 0.0105 1.72 4.763 0.5649 72953.0
21700000
6830000000
2240000000000
0.3508 0.2996 0.0016 0.0000 0.0031 0.0000 0.0062 0.0015 0.0171 0.0067 0.0715 0.0340 0.0964 0.0503 0.1026 0.0392 0.1291 0.0673 0.5723 0.8010 0.0010 0.0000 0.0019 0.0000 0.0019 0.0000 0.0057 0.0040 0.0306 0.0224 0.0373 0.0369 0.0335 0.0257 0.0450 0.0383 0.8431 0.8727 0.0025 0.0000 0.0000 0.0000 0.0100 0.0061 0.0124 0.0549 0.0423 0.0610 0.0547 0.0549 0.0448 0.1220 0.0821 0.0854 0.7512 0.6159 0.0000 0.0029 0.0015 0.0059 0.0337 0.0527 0.0366 0.0439 0.8228 7 8 9 10 11 15 28 57 188 0.1752 2.71 2.781 0.6871 17493.2
7830000
4090000000
2340000000000
0.4255 0.2007 0.0273 0.0043 0.0648 0.0086 0.1297 0.0114 0.2150 0.0643 0.2116 0.1186 0.1502 0.1686 0.1229 0.1429 0.0614 0.1629 0.0171 0.3186 0.0031 0.0010 0.0037 0.0021 0.0074 0.0026 0.0155 0.0129 0.0372 0.0290 0.0440 0.0403 0.0415 0.0445 0.0551 0.0672 0.7926 0.8004 0.0000 0.0000 0.0030 0.0000 0.0023 0.0024 0.0053 0.0097 0.0371 0.0308 0.0393 0.0559 0.0446 0.0454 0.0598 0.0608 0.8086 0.7950 0.0000 0.0021 0.0049 0.0119 0.0295 0.0372 0.0400 0.0534 0.8209
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 946 911 image if available 326 5218 83.2 12.55 6.61 2.23 66 72 76 80 84 87 90 94 100 0.0922 481 0.870 40.79 10.82 5 0.2883 94 0.0484 1.29 3.265 0.6193 7072.0
613833
54300000
4880000000
0.3970 0.2342 0.0039 0.0000 0.0039 0.0000 0.0078 0.0000 0.0310 0.0153 0.0698 0.0429 0.1512 0.0798 0.1163 0.0583 0.1860 0.0828 0.4302 0.7209 0.0034 0.0000 0.0000 0.0000 0.0069 0.0000 0.0206 0.0153 0.0309 0.0429 0.0997 0.0798 0.0550 0.0583 0.0928 0.0828 0.6907 0.7209 0.0303 0.0000 0.0909 0.0000 0.0909 0.0000 0.1818 0.0000 0.1818 0.0000 0.2121 0.0000 0.1212 0.0000 0.0606 0.0000 0.0303 0.0000 0.0055 0.0000 0.0110 0.0440 0.0714 0.1484 0.1154 0.2033 0.4011 4 5 6 6 6 7 7 9 9 0.0270 9.36 4.124 0.3431 48.6
391.422
3419.3
32319.8
0.5324 0.1461 0.0043 0.0011 0.0274 0.0040 0.0990 0.0214 0.1877 0.0631 0.2444 0.1213 0.2369 0.2069 0.1372 0.2618 0.0545 0.2256 0.0086 0.0948 0.0005 0.0002 0.0028 0.0019 0.0165 0.0091 0.0505 0.0369 0.1170 0.0831 0.1931 0.1470 0.2540 0.2323 0.2307 0.2820 0.1350 0.2075 0.1429 0.4528 0.2778 0.2397 0.2169 0.0896 0.1614 0.0557 0.0750 0.0436 0.0547 0.0533 0.0335 0.0412 0.0247 0.0194 0.0132 0.0048 0.0201 0.0768 0.1695 0.2209 0.1962 0.1531 0.0866 0.0497 0.0271
MCF7 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 1201 147 image if available 25401 21792 80.3 36.47 7.79 3.16 47 51 55 60 67 79 95 111 130 0.0646 1407 0.643 109.48 22.02 3 0.0122 311 0.0238 1.54 4.339 0.6433 7784.7
930349
141000000
27400000000
0.3746 0.2574 0.0183 0.0041 0.0285 0.0101 0.0332 0.0165 0.0445 0.0216 0.0579 0.0307 0.0760 0.0454 0.0991 0.0645 0.1547 0.1011 0.4878 0.7059 0.0063 0.0025 0.0088 0.0051 0.0101 0.0093 0.0128 0.0127 0.0158 0.0171 0.0202 0.0254 0.0263 0.0353 0.0450 0.0545 0.8547 0.8381 0.0029 0.0096 0.0051 0.0076 0.0087 0.0135 0.0154 0.0237 0.0181 0.0317 0.0252 0.0416 0.0356 0.0590 0.0614 0.0833 0.8277 0.7300 0.0039 0.0045 0.0066 0.0106 0.0121 0.0194 0.0250 0.0402 0.8777 4 5 6 7 8 9 9 10 12 0.3288 0.54 1.489 0.7679 70.7
710.738
7758.34
90867.1
0.5651 0.1468 0.0276 0.0002 0.1012 0.0027 0.1830 0.0162 0.2395 0.0448 0.2232 0.1065 0.1440 0.1983 0.0622 0.2724 0.0175 0.2494 0.0018 0.1095 0.0011 0.0001 0.0095 0.0007 0.0313 0.0047 0.0743 0.0148 0.1392 0.0405 0.2209 0.1002 0.2544 0.1989 0.1985 0.3291 0.0707 0.3109 0.0837 0.3817 0.2220 0.3524 0.2715 0.1695 0.2102 0.0699 0.1317 0.0232 0.0547 0.0028 0.0218 0.0004 0.0035 0.0000 0.0010 0.0000 0.0061 0.0422 0.1149 0.1974 0.2403 0.2128 0.1308 0.0484 0.0072
MCF7 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 841 100 image if available 7377 24941 386.3 96.75 88.88 190.82 262 298 330 360 385 408 433 466 515 0.0500 1246 0.563 94.76 26.17 2 0.0409 302 0.0008 47.55 7.415 0.1751 158588.0
68800000
31400000000
15000000000000
0.4311 0.2177 0.0002 0.0000 0.0031 0.0005 0.0070 0.0012 0.0283 0.0041 0.0813 0.0252 0.1505 0.0529 0.1401 0.0558 0.1607 0.0799 0.4286 0.7805 0.0000 0.0000 0.0011 0.0001 0.0023 0.0003 0.0099 0.0018 0.0340 0.0163 0.0593 0.0332 0.0508 0.0272 0.0661 0.0402 0.7764 0.8808 0.0040 0.0130 0.0066 0.0238 0.0139 0.0563 0.0615 0.0909 0.1315 0.1970 0.1606 0.1710 0.1269 0.1255 0.1401 0.1299 0.3549 0.1926 0.0005 0.0014 0.0043 0.0220 0.0674 0.1016 0.1003 0.1272 0.5753 4 5 7 8 10 12 18 103 322 0.1971 13.23 3.393 0.6457 44309.3
31100000
25500000000
23000000000000
0.4510 0.1554 0.0309 0.0028 0.1373 0.0130 0.2921 0.0763 0.2205 0.1516 0.1431 0.2140 0.0986 0.1898 0.0271 0.1395 0.0213 0.1116 0.0290 0.1014 0.0000 0.0003 0.0009 0.0005 0.0007 0.0016 0.0037 0.0063 0.0213 0.0191 0.0374 0.0318 0.0250 0.0278 0.0407 0.0377 0.8703 0.8748 0.0000 0.0002 0.0008 0.0004 0.0004 0.0019 0.0063 0.0064 0.0259 0.0282 0.0468 0.0526 0.0377 0.0404 0.0539 0.0614 0.8281 0.8084 0.0000 0.0004 0.0008 0.0042 0.0213 0.0423 0.0293 0.0477 0.8540
MDA-MB-231
0
DRAQ5 1 TMRE 2 2 2 1 1217 492 image if available 4158 8748 478.3 77.87 112.81 236.09 376 414 441 464 483 499 516 535 574 0.0725 634 0.983 79.31 27.31 1 0.0536 223 0.0016 22.49 6.757 0.2408 234837.0
118000000
60800000000
31900000000000
0.3975 0.2479 0.0000 0.0000 0.0003 0.0000 0.0003 0.0000 0.0070 0.0005 0.0263 0.0161 0.0444 0.0266 0.0456 0.0159 0.0702 0.0242 0.8058 0.9168 0.0000 0.0000 0.0003 0.0000 0.0000 0.0000 0.0030 0.0002 0.0174 0.0145 0.0277 0.0252 0.0261 0.0128 0.0397 0.0206 0.8859 0.9267 0.0048 0.0000 0.0048 0.0000 0.0096 0.0556 0.0264 0.0833 0.0769 0.1667 0.0817 0.1389 0.1082 0.1667 0.1034 0.1111 0.5841 0.2778 0.0014 0.0018 0.0063 0.0136 0.0407 0.0678 0.0691 0.0985 0.7010 5 7 8 9 10 12 22 146 413 0.1638 17.76 3.315 0.5824 68457.9
58700000
59900000000
68200000000000
0.3262 0.2943 0.0588 0.0025 0.2888 0.0296 0.2513 0.1605 0.1016 0.1951 0.1123 0.1975 0.0695 0.1383 0.1016 0.0864 0.0107 0.0963 0.0053 0.0938 0.0000 0.0000 0.0000 0.0009 0.0000 0.0005 0.0081 0.0076 0.0389 0.0360 0.0567 0.0536 0.0354 0.0337 0.0445 0.0469 0.8164 0.8208 0.0006 0.0006 0.0000 0.0012 0.0045 0.0041 0.0078 0.0088 0.0380 0.0364 0.0553 0.0634 0.0330 0.0346 0.0508 0.0511 0.8101 0.7999 0.0000 0.0000 0.0005 0.0123 0.0410 0.0511 0.0373 0.0453 0.8125
MCF 10A
0
DRAQ5 1 TMRE 2 2 2 1 1235 928 image if available 3908 866 131.6 35.52 83.99 75.24 92 104 113 120 128 134 143 154 171 0.5855 507 1.261 98.62 31.32 1 0.0581 227 0.0023 24.71 6.369 0.2431 18576.3
2850000
480000000
90700000000
0.4962 0.1800 0.0025 0.0000 0.0025 0.0003 0.0091 0.0020 0.0313 0.0045 0.0844 0.0247 0.1671 0.0656 0.1560 0.0617 0.1844 0.1041 0.3627 0.7372 0.0000 0.0000 0.0013 0.0003 0.0026 0.0016 0.0107 0.0024 0.0488 0.0200 0.0837 0.0431 0.0755 0.0318 0.1153 0.0568 0.6620 0.8442 0.0109 0.0207 0.0125 0.0290 0.0498 0.0290 0.0888 0.1079 0.1495 0.1992 0.1947 0.1826 0.1137 0.0747 0.1340 0.1452 0.2461 0.2116 0.0012 0.0075 0.0184 0.0519 0.1308 0.1360 0.1314 0.1527 0.3700 16 24 36 50 62 79 105 130 176 0.0070 32.32 5.471 0.3545 12708.8
3020000
1050000000
473000000000
0.5943 0.0759 0.0880 0.0099 0.2240 0.0627 0.2160 0.0924 0.2480 0.1881 0.1600 0.2277 0.0560 0.2376 0.0080 0.0792 0.0000 0.0528 0.0000 0.0495 0.0150 0.0019 0.0200 0.0174 0.0324 0.0174 0.0549 0.0581 0.2893 0.2364 0.3566 0.3682 0.1322 0.1492 0.0574 0.0717 0.0424 0.0795 0.0072 0.0047 0.0217 0.0235 0.0580 0.0798 0.1051 0.1221 0.2754 0.2864 0.3370 0.3146 0.1123 0.0986 0.0507 0.0376 0.0326 0.0329 0.0151 0.0151 0.0272 0.1057 0.2779 0.3595 0.1178 0.0453 0.0363
MDA-MB-231 Barasertib
1.1
uM
DRAQ5 1 TMRE 2 1 16 1 561 247 image if available 4445 15033 466.1 65.09 63.62 138.06 379 413 433 450 466 481 499 521 551 0.0559 840 1.186 46.40 17.49 1 0.0270 120 0.0015 34.76 6.820 0.2169 221513.0
107000000
52800000000
26400000000000
0.4116 0.2311 0.0000 0.0000 0.0000 0.0000 0.0011 0.0000 0.0035 0.0002 0.0355 0.0137 0.0646 0.0248 0.0635 0.0142 0.0910 0.0205 0.7407 0.9266 0.0000 0.0000 0.0000 0.0000 0.0002 0.0000 0.0020 0.0002 0.0221 0.0137 0.0368 0.0248 0.0314 0.0142 0.0456 0.0187 0.8620 0.9284 0.0110 1.0000 0.0192 0.0000 0.0219 0.0000 0.0959 0.0000 0.1479 0.0000 0.1726 0.0000 0.1397 0.0000 0.1288 0.0000 0.2630 0.0000 0.0004 0.0036 0.0085 0.0278 0.0732 0.0996 0.0961 0.1302 0.5606 7 8 9 10 12 15 22 57 200 0.2619 11.61 3.053 0.7574 23105.5
14100000
11000000000
10100000000000
0.4691 0.1844 0.0363 0.0081 0.0726 0.0208 0.0726 0.0728 0.1501 0.0786 0.1622 0.1110 0.1671 0.1260 0.1574 0.1191 0.1090 0.1445 0.0726 0.3191 0.0003 0.0012 0.0013 0.0030 0.0023 0.0044 0.0077 0.0094 0.0229 0.0195 0.0265 0.0301 0.0245 0.0248 0.0368 0.0387 0.8777 0.8689 0.0011 0.0000 0.0011 0.0004 0.0022 0.0024 0.0108 0.0091 0.0238 0.0234 0.0309 0.0313 0.0313 0.0317 0.0395 0.0527 0.8593 0.8490 0.0003 0.0007 0.0048 0.0104 0.0214 0.0308 0.0235 0.0443 0.8637
BT-20 A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 902 305 image if available 577 1224 107.4 19.71 5.63 1.94 82 89 96 101 108 113 118 125 133 0.2230 273 1.197 35.36 14.21 1 0.1664 96 0.0277 1.58 3.824 0.5880 11913.2
1360000
161000000
19400000000
0.3940 0.2372 0.0000 0.0000 0.0025 0.0000 0.0051 0.0000 0.0304 0.0018 0.0658 0.0406 0.1392 0.0689 0.1342 0.0548 0.1519 0.0707 0.4709 0.7633 0.0000 0.0000 0.0020 0.0000 0.0000 0.0000 0.0143 0.0017 0.0369 0.0399 0.0656 0.0624 0.0615 0.0295 0.0820 0.0503 0.7377 0.8163 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0968 0.6364 0.1290 0.1818 0.2796 0.0909 0.1075 0.0909 0.1398 0.0000 0.2473 0.0000 0.0034 0.0068 0.0169 0.0203 0.0811 0.0980 0.0743 0.0845 0.6149 3 4 4 5 5 6 7 7 8 0.0263 7.62 3.939 0.3680 35.5
244.168
1810.28
14316.1
0.5714 0.1153 0.0047 0.0000 0.0712 0.0040 0.1377 0.0160 0.2389 0.0419 0.2358 0.1028 0.2294 0.1766 0.0585 0.2535 0.0190 0.2685 0.0047 0.1367 0.0000 0.0000 0.0154 0.0019 0.0475 0.0065 0.1342 0.0260 0.1853 0.0854 0.2601 0.1365 0.1936 0.2201 0.1211 0.2934 0.0428 0.2303 0.3190 0.5467 0.3667 0.3333 0.1571 0.1067 0.1238 0.0133 0.0286 0.0000 0.0048 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0000 0.0280 0.1226 0.1559 0.1961 0.2259 0.1471 0.0753 0.0350 0.0140
Hs 578T A443654
10
uM
DRAQ5 1 TMRE 2 1 11 1 477 785 image if available 2057 7126 15.8 5.35 5.58 1.94 10 11 13 14 15 16 18 20 22 0.1343 957 1.077 39.62 14.00 0 0.0501 103 0.0083 6.76 5.098 0.3940 278.8
5536.95
125712
3300000
0.3803 0.2578 0.0068 0.0000 0.0241 0.0017 0.0395 0.0081 0.0656 0.0237 0.1070 0.0317 0.1466 0.0531 0.1688 0.1073 0.2054 0.1604 0.2363 0.6140 0.0048 0.0000 0.0131 0.0010 0.0220 0.0068 0.0275 0.0167 0.0440 0.0256 0.0557 0.0329 0.0688 0.0605 0.0922 0.0924 0.6717 0.7641 0.0168 0.0437 0.0216 0.0437 0.0481 0.0328 0.0793 0.0656 0.0865 0.1038 0.1346 0.1093 0.1298 0.0710 0.1394 0.1749 0.3438 0.3552 0.0178 0.0231 0.0241 0.0409 0.0409 0.0682 0.0860 0.1091 0.5897 3 4 5 5 5 6 6 7 8 0.0254 8.33 4.093 0.3635 34.9
237.89
1743
13611.8
0.5441 0.1416 0.0029 0.0002 0.0262 0.0017 0.0867 0.0113 0.1633 0.0354 0.2318 0.0789 0.2315 0.1447 0.1584 0.2575 0.0821 0.2968 0.0170 0.1734 0.0004 0.0002 0.0045 0.0006 0.0189 0.0043 0.0680 0.0220 0.1231 0.0509 0.2194 0.0876 0.2719 0.1709 0.2172 0.3403 0.0767 0.3232 0.2384 0.4990 0.3216 0.3638 0.2659 0.1113 0.1235 0.0258 0.0369 0.0000 0.0129 0.0000 0.0009 0.0000 0.0000 0.0000 0.0000 0.0000 0.0115 0.0662 0.1649 0.2477 0.2359 0.1587 0.0825 0.0266 0.0059