High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 927 | 522 | | 3614 | 6289 | 297.5 | 144.28 | 59.44 | 77.60 | 127 | 157 | 192 | 233 | 266 | 305 | 406 | 465 | 511 | 0.1040 | 654 | 1.229 | 109.25 | 47.52 | 2 | 0.0819 | 296 | 0.0028 | 6.07 | 6.131 | 0.4083 | 109347.0 | 45800000 | 20700000000 | 9820000000000 | 0.3640 | 0.2549 | 0.0012 | 0.0000 | 0.0012 | 0.0006 | 0.0036 | 0.0025 | 0.0324 | 0.0086 | 0.1032 | 0.0531 | 0.1429 | 0.0834 | 0.1273 | 0.0562 | 0.1020 | 0.0828 | 0.4862 | 0.7128 | 0.0005 | 0.0000 | 0.0005 | 0.0004 | 0.0005 | 0.0015 | 0.0076 | 0.0030 | 0.0219 | 0.0203 | 0.0343 | 0.0263 | 0.0281 | 0.0192 | 0.0357 | 0.0312 | 0.8710 | 0.8980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0039 | 0.0331 | 0.0347 | 0.0410 | 0.0597 | 0.0316 | 0.0414 | 0.0458 | 0.0462 | 0.8469 | 0.8141 | 0.0020 | 0.0013 | 0.0027 | 0.0054 | 0.0229 | 0.0404 | 0.0242 | 0.0310 | 0.8700 | 8 | 11 | 14 | 19 | 26 | 38 | 58 | 92 | 162 | 0.0962 | 2.42 | 3.459 | 0.6933 | 9553.8 | 2410000 | 755000000 | 271000000000 | 0.5400 | 0.1318 | 0.0018 | 0.0033 | 0.0126 | 0.0122 | 0.0650 | 0.0236 | 0.1733 | 0.0447 | 0.2365 | 0.0943 | 0.2166 | 0.1561 | 0.1480 | 0.1423 | 0.1137 | 0.1740 | 0.0325 | 0.3496 | 0.0000 | 0.0015 | 0.0005 | 0.0034 | 0.0032 | 0.0076 | 0.0142 | 0.0125 | 0.0500 | 0.0386 | 0.0866 | 0.0773 | 0.0596 | 0.0583 | 0.0830 | 0.0735 | 0.7030 | 0.7273 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0037 | 0.0064 | 0.0197 | 0.0227 | 0.0614 | 0.0716 | 0.1020 | 0.1106 | 0.0694 | 0.0738 | 0.0860 | 0.0865 | 0.6566 | 0.6270 | 0.0011 | 0.0027 | 0.0043 | 0.0160 | 0.0543 | 0.1005 | 0.0660 | 0.0787 | 0.6766 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 182 | 324 | | 4862 | 8847 | 382.1 | 46.56 | 84.31 | 223.89 | 321 | 348 | 363 | 376 | 385 | 395 | 406 | 419 | 440 | 0.0849 | 751 | 0.869 | 141.40 | 42.45 | 2 | 0.0755 | 367 | 0.0020 | 27.89 | 6.580 | 0.2423 | 148135.0 | 58200000 | 23200000000 | 9310000000000 | 0.4327 | 0.2087 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0044 | 0.0000 | 0.0215 | 0.0134 | 0.0430 | 0.0245 | 0.0423 | 0.0117 | 0.0642 | 0.0210 | 0.8233 | 0.9294 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0153 | 0.0134 | 0.0306 | 0.0245 | 0.0237 | 0.0117 | 0.0317 | 0.0210 | 0.8966 | 0.9294 | 0.0214 | 0.0000 | 0.0856 | 0.0000 | 0.1016 | 0.0000 | 0.1283 | 0.0000 | 0.1176 | 0.0000 | 0.1444 | 0.0000 | 0.1016 | 0.0000 | 0.1123 | 0.0000 | 0.1872 | 0.0000 | 0.0019 | 0.0049 | 0.0106 | 0.0314 | 0.0538 | 0.0947 | 0.0981 | 0.1163 | 0.5883 | 8 | 9 | 11 | 12 | 13 | 15 | 20 | 43 | 199 | 0.1434 | 6.44 | 2.531 | 0.5616 | 57228.9 | 60400000 | 73600000000 | 96900000000000 | 0.7057 | 0.0462 | 0.0466 | 0.0000 | 0.0975 | 0.0157 | 0.2458 | 0.0747 | 0.1144 | 0.1041 | 0.1653 | 0.1434 | 0.1483 | 0.1945 | 0.1102 | 0.1611 | 0.0466 | 0.1336 | 0.0254 | 0.1729 | 0.0007 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0048 | 0.0144 | 0.0133 | 0.0390 | 0.0387 | 0.0787 | 0.0678 | 0.0568 | 0.0599 | 0.1026 | 0.0998 | 0.7066 | 0.7145 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0016 | 0.0009 | 0.0122 | 0.0192 | 0.0636 | 0.0603 | 0.0865 | 0.0857 | 0.0530 | 0.0594 | 0.1117 | 0.0970 | 0.6713 | 0.6740 | 0.0000 | 0.0008 | 0.0023 | 0.0129 | 0.0530 | 0.0802 | 0.0560 | 0.1104 | 0.6846 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 100 | 607 | | 540 | 5580 | 379.2 | 43.12 | 73.69 | 167.23 | 318 | 337 | 353 | 372 | 384 | 393 | 405 | 418 | 436 | 0.0710 | 396 | 0.750 | 109.88 | 35.01 | 2 | 0.6222 | 336 | 0.0034 | 25.50 | 5.823 | 0.2191 | 145633.0 | 56600000 | 22300000000 | 8850000000000 | 0.3869 | 0.2443 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0080 | 0.0019 | 0.0459 | 0.0426 | 0.0719 | 0.0630 | 0.0599 | 0.0315 | 0.0719 | 0.0537 | 0.7405 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0039 | 0.0019 | 0.0426 | 0.0426 | 0.0638 | 0.0630 | 0.0329 | 0.0315 | 0.0561 | 0.0537 | 0.7988 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0625 | 0.0000 | 0.1250 | 0.0000 | 0.4375 | 0.0000 | 0.0625 | 0.0000 | 0.2500 | 0.0000 | 0.0625 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0241 | 0.0552 | 0.0897 | 0.0828 | 0.1276 | 0.6138 | 10 | 13 | 15 | 17 | 20 | 25 | 42 | 99 | 162 | 0.2249 | 3.67 | 2.655 | 0.7483 | 33390.0 | 36400000 | 52700000000 | 84800000000000 | 0.5879 | 0.1256 | 0.0385 | 0.0052 | 0.0427 | 0.0174 | 0.1026 | 0.0261 | 0.1880 | 0.0540 | 0.2222 | 0.1237 | 0.1624 | 0.1429 | 0.1496 | 0.1655 | 0.0684 | 0.2003 | 0.0256 | 0.2648 | 0.0007 | 0.0018 | 0.0014 | 0.0043 | 0.0027 | 0.0037 | 0.0075 | 0.0043 | 0.0177 | 0.0178 | 0.0198 | 0.0227 | 0.0355 | 0.0233 | 0.0539 | 0.0491 | 0.8608 | 0.8729 | 0.0000 | 0.0038 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0154 | 0.0227 | 0.0292 | 0.0360 | 0.0382 | 0.0588 | 0.0544 | 0.0682 | 0.1072 | 0.0986 | 0.7555 | 0.7024 | 0.0007 | 0.0007 | 0.0029 | 0.0059 | 0.0192 | 0.0354 | 0.0347 | 0.0560 | 0.8444 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 550 | 347 | | 2625 | 7570 | 364.6 | 100.61 | 57.27 | 93.59 | 229 | 271 | 313 | 338 | 359 | 381 | 405 | 462 | 513 | 0.0856 | 648 | 0.595 | 111.40 | 19.31 | 7 | 0.1051 | 276 | 0.0012 | 33.64 | 6.958 | 0.2138 | 143052.0 | 59700000 | 26200000000 | 12000000000000 | 0.3697 | 0.2506 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0023 | 0.0162 | 0.0079 | 0.0855 | 0.0410 | 0.1179 | 0.0843 | 0.0929 | 0.0531 | 0.0899 | 0.0754 | 0.5969 | 0.7346 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0016 | 0.0333 | 0.0276 | 0.0455 | 0.0470 | 0.0414 | 0.0272 | 0.0510 | 0.0404 | 0.8253 | 0.8549 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0216 | 0.0225 | 0.0396 | 0.0722 | 0.1367 | 0.1075 | 0.2086 | 0.0690 | 0.1223 | 0.1043 | 0.1295 | 0.6244 | 0.3309 | 0.0000 | 0.0008 | 0.0048 | 0.0191 | 0.0590 | 0.0901 | 0.0726 | 0.0989 | 0.6547 | 8 | 10 | 12 | 14 | 18 | 23 | 38 | 87 | 161 | 0.1461 | 5.86 | 3.394 | 0.7357 | 12038.0 | 4300000 | 1950000000 | 1010000000000 | 0.6794 | 0.0692 | 0.0238 | 0.0092 | 0.0506 | 0.0184 | 0.1131 | 0.0407 | 0.1310 | 0.0512 | 0.2292 | 0.1168 | 0.2083 | 0.1444 | 0.1280 | 0.1470 | 0.0893 | 0.1745 | 0.0268 | 0.2979 | 0.0019 | 0.0025 | 0.0014 | 0.0038 | 0.0068 | 0.0059 | 0.0106 | 0.0106 | 0.0323 | 0.0317 | 0.0651 | 0.0571 | 0.0458 | 0.0440 | 0.0719 | 0.0693 | 0.7641 | 0.7751 | 0.0006 | 0.0000 | 0.0012 | 0.0006 | 0.0035 | 0.0075 | 0.0098 | 0.0106 | 0.0368 | 0.0399 | 0.0725 | 0.0761 | 0.0478 | 0.0586 | 0.0725 | 0.0773 | 0.7553 | 0.7294 | 0.0005 | 0.0011 | 0.0053 | 0.0090 | 0.0329 | 0.0638 | 0.0515 | 0.0733 | 0.7625 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1251 | 480 | | 6017 | 19160 | 372.6 | 81.16 | 69.86 | 92.27 | 278 | 301 | 322 | 342 | 361 | 382 | 404 | 437 | 483 | 0.0573 | 1098 | 1.122 | 78.10 | 30.02 | 1 | 0.0346 | 208 | 0.0012 | 27.16 | 6.956 | 0.2116 | 145447.0 | 59500000 | 25500000000 | 11400000000000 | 0.4095 | 0.2372 | 0.0010 | 0.0000 | 0.0018 | 0.0002 | 0.0054 | 0.0002 | 0.0137 | 0.0014 | 0.0485 | 0.0173 | 0.0996 | 0.0335 | 0.1201 | 0.0274 | 0.1504 | 0.0393 | 0.5594 | 0.8807 | 0.0008 | 0.0000 | 0.0010 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0002 | 0.0212 | 0.0113 | 0.0414 | 0.0210 | 0.0549 | 0.0125 | 0.0676 | 0.0208 | 0.8040 | 0.9343 | 0.0038 | 0.0028 | 0.0086 | 0.0111 | 0.0250 | 0.0111 | 0.0547 | 0.0474 | 0.0960 | 0.1393 | 0.1353 | 0.1309 | 0.0988 | 0.0919 | 0.1180 | 0.1727 | 0.4597 | 0.3928 | 0.0011 | 0.0007 | 0.0108 | 0.0310 | 0.0601 | 0.1045 | 0.0952 | 0.1153 | 0.5812 | 6 | 8 | 10 | 14 | 25 | 44 | 75 | 126 | 201 | 0.0798 | 9.76 | 4.599 | 0.5642 | 13394.3 | 3680000 | 1220000000 | 456000000000 | 0.4787 | 0.1430 | 0.0265 | 0.0016 | 0.1013 | 0.0063 | 0.2053 | 0.0393 | 0.1849 | 0.0976 | 0.1931 | 0.1897 | 0.1292 | 0.1970 | 0.0802 | 0.1581 | 0.0578 | 0.1362 | 0.0218 | 0.1742 | 0.0009 | 0.0003 | 0.0015 | 0.0010 | 0.0025 | 0.0039 | 0.0136 | 0.0110 | 0.0410 | 0.0369 | 0.0620 | 0.0559 | 0.0496 | 0.0499 | 0.0745 | 0.0671 | 0.7545 | 0.7740 | 0.0004 | 0.0013 | 0.0013 | 0.0013 | 0.0026 | 0.0023 | 0.0149 | 0.0153 | 0.0444 | 0.0503 | 0.0766 | 0.0916 | 0.0638 | 0.0652 | 0.0850 | 0.0913 | 0.7110 | 0.6815 | 0.0005 | 0.0017 | 0.0028 | 0.0150 | 0.0394 | 0.0700 | 0.0556 | 0.0763 | 0.7387 | ||
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 382 | 919 | | 6897 | 11121 | 362.8 | 74.41 | 225.10 | 252.79 | 267 | 298 | 321 | 341 | 358 | 379 | 401 | 427 | 462 | 0.0739 | 822 | 1.086 | 120.93 | 34.41 | 1 | 0.0406 | 280 | 0.0009 | 36.87 | 7.251 | 0.1983 | 137149.0 | 53900000 | 21900000000 | 9220000000000 | 0.4314 | 0.2131 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0005 | 0.0135 | 0.0012 | 0.0506 | 0.0134 | 0.0981 | 0.0302 | 0.1155 | 0.0258 | 0.1361 | 0.0368 | 0.5832 | 0.8921 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0002 | 0.0004 | 0.0061 | 0.0010 | 0.0215 | 0.0104 | 0.0426 | 0.0219 | 0.0481 | 0.0148 | 0.0570 | 0.0214 | 0.8240 | 0.9300 | 0.0050 | 0.0000 | 0.0075 | 0.0000 | 0.0199 | 0.0000 | 0.0489 | 0.0000 | 0.1095 | 0.0000 | 0.1376 | 0.0000 | 0.1086 | 0.0000 | 0.1327 | 0.0000 | 0.4303 | 0.0000 | 0.0003 | 0.0024 | 0.0055 | 0.0240 | 0.0518 | 0.1046 | 0.0888 | 0.1001 | 0.6225 | 16 | 19 | 26 | 60 | 133 | 209 | 292 | 408 | 608 | 0.0252 | 45.18 | 5.945 | 0.4029 | 114568.0 | 77900000 | 62700000000 | 56900000000000 | 0.5295 | 0.1405 | 0.0233 | 0.0008 | 0.1395 | 0.0101 | 0.2197 | 0.0563 | 0.1828 | 0.1049 | 0.1612 | 0.1734 | 0.1275 | 0.1937 | 0.0762 | 0.1418 | 0.0489 | 0.1329 | 0.0209 | 0.1860 | 0.0004 | 0.0002 | 0.0004 | 0.0004 | 0.0021 | 0.0016 | 0.0092 | 0.0085 | 0.0536 | 0.0397 | 0.0929 | 0.0707 | 0.0709 | 0.0541 | 0.1009 | 0.0724 | 0.6695 | 0.7524 | 0.0003 | 0.0010 | 0.0008 | 0.0029 | 0.0058 | 0.0059 | 0.0202 | 0.0280 | 0.0810 | 0.0982 | 0.1221 | 0.1321 | 0.0928 | 0.0956 | 0.1260 | 0.1337 | 0.5510 | 0.5026 | 0.0000 | 0.0010 | 0.0036 | 0.0157 | 0.0703 | 0.1098 | 0.0834 | 0.1150 | 0.6013 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 550 | 588 | | 3961 | 12702 | 362.6 | 74.74 | 145.47 | 313.98 | 267 | 301 | 325 | 344 | 362 | 380 | 400 | 423 | 452 | 0.0624 | 793 | 1.103 | 133.51 | 42.58 | 1 | 0.0836 | 331 | 0.0009 | 60.00 | 7.202 | 0.1727 | 137032.0 | 53800000 | 22000000000 | 9300000000000 | 0.4189 | 0.2240 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0191 | 0.0008 | 0.0484 | 0.0174 | 0.0949 | 0.0441 | 0.1019 | 0.0284 | 0.1484 | 0.0412 | 0.5837 | 0.8681 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0067 | 0.0008 | 0.0179 | 0.0148 | 0.0363 | 0.0309 | 0.0312 | 0.0140 | 0.0515 | 0.0197 | 0.8556 | 0.9198 | 0.0035 | 0.0177 | 0.0209 | 0.0088 | 0.0435 | 0.0796 | 0.1009 | 0.1504 | 0.1687 | 0.1770 | 0.1965 | 0.2566 | 0.1287 | 0.0442 | 0.1270 | 0.1150 | 0.2104 | 0.1504 | 0.0015 | 0.0025 | 0.0066 | 0.0207 | 0.0673 | 0.1037 | 0.0967 | 0.1463 | 0.5547 | 8 | 11 | 14 | 21 | 33 | 53 | 90 | 169 | 374 | 0.0996 | 33.81 | 4.438 | 0.6074 | 119740.0 | 178000000 | 330000000000 | 679000000000000 | 0.4919 | 0.1485 | 0.0193 | 0.0012 | 0.1035 | 0.0094 | 0.2190 | 0.0528 | 0.2154 | 0.0944 | 0.2106 | 0.1812 | 0.1408 | 0.2223 | 0.0590 | 0.1554 | 0.0217 | 0.1384 | 0.0108 | 0.1449 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0018 | 0.0021 | 0.0121 | 0.0100 | 0.0667 | 0.0554 | 0.1113 | 0.0915 | 0.0640 | 0.0610 | 0.0969 | 0.0879 | 0.6473 | 0.6909 | 0.0000 | 0.0005 | 0.0024 | 0.0064 | 0.0064 | 0.0055 | 0.0189 | 0.0132 | 0.0781 | 0.0783 | 0.1305 | 0.1429 | 0.0673 | 0.0660 | 0.0995 | 0.1051 | 0.5969 | 0.5822 | 0.0003 | 0.0007 | 0.0031 | 0.0146 | 0.0809 | 0.1122 | 0.0729 | 0.0983 | 0.6170 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 976 | 656 | | 13290 | 29012 | 350.5 | 83.54 | 117.42 | 202.47 | 252 | 284 | 306 | 327 | 348 | 369 | 393 | 419 | 457 | 0.0458 | 1328 | 1.206 | 145.66 | 51.35 | 3 | 0.0266 | 354 | 0.0009 | 33.81 | 7.228 | 0.1932 | 129853.0 | 50400000 | 20400000000 | 8570000000000 | 0.4626 | 0.1869 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0137 | 0.0009 | 0.0626 | 0.0154 | 0.1394 | 0.0357 | 0.1429 | 0.0364 | 0.1618 | 0.0560 | 0.4786 | 0.8556 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0047 | 0.0002 | 0.0239 | 0.0104 | 0.0583 | 0.0216 | 0.0527 | 0.0167 | 0.0693 | 0.0259 | 0.7910 | 0.9253 | 0.0016 | 0.0134 | 0.0070 | 0.0202 | 0.0147 | 0.0353 | 0.0609 | 0.1109 | 0.1230 | 0.1681 | 0.1707 | 0.1983 | 0.1145 | 0.1059 | 0.1486 | 0.1345 | 0.3589 | 0.2134 | 0.0002 | 0.0012 | 0.0066 | 0.0185 | 0.0678 | 0.1107 | 0.0917 | 0.1206 | 0.5827 | 6 | 7 | 9 | 10 | 12 | 24 | 88 | 206 | 406 | 0.1454 | 15.57 | 3.922 | 0.5837 | 54782.0 | 35700000 | 27800000000 | 24300000000000 | 0.5329 | 0.1352 | 0.0637 | 0.0030 | 0.1850 | 0.0394 | 0.2305 | 0.1421 | 0.1607 | 0.1285 | 0.1562 | 0.1739 | 0.0925 | 0.1834 | 0.0652 | 0.1156 | 0.0326 | 0.0940 | 0.0136 | 0.1201 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0013 | 0.0098 | 0.0088 | 0.0421 | 0.0384 | 0.0678 | 0.0575 | 0.0453 | 0.0456 | 0.0680 | 0.0641 | 0.7645 | 0.7842 | 0.0000 | 0.0003 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0116 | 0.0124 | 0.0523 | 0.0544 | 0.0850 | 0.0971 | 0.0615 | 0.0646 | 0.0847 | 0.0903 | 0.7028 | 0.6776 | 0.0004 | 0.0005 | 0.0019 | 0.0076 | 0.0494 | 0.0725 | 0.0487 | 0.0795 | 0.7395 |
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 318 | 872 | | 12186 | 25790 | 350.1 | 84.35 | 180.74 | 231.33 | 250 | 278 | 300 | 319 | 340 | 362 | 386 | 419 | 463 | 0.0459 | 1185 | 1.241 | 90.52 | 37.58 | 1 | 0.0197 | 240 | 0.0006 | 79.84 | 7.705 | 0.1428 | 129698.0 | 50800000 | 21000000000 | 9160000000000 | 0.4637 | 0.1985 | 0.0008 | 0.0000 | 0.0050 | 0.0002 | 0.0093 | 0.0019 | 0.0269 | 0.0039 | 0.0810 | 0.0184 | 0.1487 | 0.0417 | 0.1625 | 0.0489 | 0.1712 | 0.0732 | 0.3947 | 0.8118 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0001 | 0.0091 | 0.0003 | 0.0330 | 0.0101 | 0.0662 | 0.0219 | 0.0745 | 0.0199 | 0.0941 | 0.0344 | 0.7203 | 0.9133 | 0.0050 | 0.0088 | 0.0083 | 0.0113 | 0.0190 | 0.0479 | 0.0690 | 0.1614 | 0.1467 | 0.1589 | 0.1789 | 0.2320 | 0.1149 | 0.1236 | 0.1471 | 0.1097 | 0.3112 | 0.1463 | 0.0009 | 0.0031 | 0.0086 | 0.0355 | 0.0810 | 0.1311 | 0.1118 | 0.1336 | 0.4943 | 10 | 15 | 25 | 45 | 80 | 130 | 204 | 324 | 514 | 0.0440 | 29.42 | 5.543 | 0.4890 | 86176.2 | 59000000 | 49700000000 | 48200000000000 | 0.4861 | 0.1546 | 0.0520 | 0.0023 | 0.1701 | 0.0129 | 0.2665 | 0.0966 | 0.1459 | 0.1378 | 0.1201 | 0.1935 | 0.1172 | 0.1886 | 0.0605 | 0.1155 | 0.0372 | 0.1007 | 0.0305 | 0.1521 | 0.0003 | 0.0004 | 0.0012 | 0.0006 | 0.0023 | 0.0023 | 0.0133 | 0.0093 | 0.0591 | 0.0486 | 0.0997 | 0.0816 | 0.0694 | 0.0558 | 0.1037 | 0.0915 | 0.6512 | 0.7099 | 0.0005 | 0.0003 | 0.0007 | 0.0026 | 0.0046 | 0.0032 | 0.0156 | 0.0218 | 0.0784 | 0.0855 | 0.1293 | 0.1333 | 0.0752 | 0.0852 | 0.1163 | 0.1277 | 0.5793 | 0.5404 | 0.0006 | 0.0014 | 0.0033 | 0.0161 | 0.0656 | 0.1205 | 0.0715 | 0.1126 | 0.6084 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1074 | 329 | | 10716 | 23313 | 347.7 | 91.75 | 73.56 | 114.94 | 242 | 269 | 292 | 314 | 335 | 358 | 384 | 417 | 474 | 0.0592 | 1380 | 0.979 | 123.69 | 46.10 | 1 | 0.0314 | 336 | 0.0009 | 44.10 | 7.309 | 0.1906 | 129299.0 | 51400000 | 21900000000 | 9900000000000 | 0.4246 | 0.2290 | 0.0002 | 0.0000 | 0.0013 | 0.0000 | 0.0081 | 0.0003 | 0.0209 | 0.0023 | 0.0739 | 0.0236 | 0.1547 | 0.0469 | 0.1487 | 0.0470 | 0.1829 | 0.0798 | 0.4092 | 0.8000 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0001 | 0.0067 | 0.0011 | 0.0320 | 0.0128 | 0.0693 | 0.0240 | 0.0655 | 0.0222 | 0.0943 | 0.0426 | 0.7287 | 0.8973 | 0.0038 | 0.0033 | 0.0108 | 0.0043 | 0.0169 | 0.0174 | 0.0606 | 0.0587 | 0.0983 | 0.1293 | 0.1396 | 0.1772 | 0.0973 | 0.1283 | 0.1189 | 0.1533 | 0.4537 | 0.3283 | 0.0011 | 0.0027 | 0.0078 | 0.0287 | 0.0782 | 0.1249 | 0.0938 | 0.1276 | 0.5352 | 5 | 6 | 8 | 9 | 13 | 34 | 72 | 133 | 226 | 0.0834 | 10.03 | 3.982 | 0.5196 | 18622.6 | 7300000 | 3800000000 | 2450000000000 | 0.4789 | 0.1814 | 0.0998 | 0.0031 | 0.2338 | 0.0435 | 0.2680 | 0.1682 | 0.1369 | 0.1634 | 0.1119 | 0.1864 | 0.0720 | 0.1590 | 0.0371 | 0.0956 | 0.0306 | 0.0815 | 0.0100 | 0.0993 | 0.0004 | 0.0001 | 0.0003 | 0.0006 | 0.0013 | 0.0018 | 0.0095 | 0.0100 | 0.0610 | 0.0508 | 0.0917 | 0.0745 | 0.0604 | 0.0548 | 0.1046 | 0.0852 | 0.6708 | 0.7222 | 0.0002 | 0.0004 | 0.0018 | 0.0009 | 0.0024 | 0.0034 | 0.0180 | 0.0181 | 0.0720 | 0.0856 | 0.1220 | 0.1315 | 0.0802 | 0.0846 | 0.1175 | 0.1264 | 0.5860 | 0.5492 | 0.0001 | 0.0003 | 0.0026 | 0.0135 | 0.0658 | 0.1063 | 0.0699 | 0.1141 | 0.6274 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1040 | 910 | | 3585 | 10231 | 344.3 | 84.59 | 34.10 | 76.86 | 243 | 270 | 294 | 317 | 338 | 360 | 384 | 412 | 458 | 0.0777 | 795 | 0.975 | 80.16 | 26.08 | 1 | 0.0555 | 199 | 0.0010 | 48.18 | 7.091 | 0.1715 | 125705.0 | 48500000 | 19700000000 | 8380000000000 | 0.4417 | 0.2214 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0058 | 0.0006 | 0.0346 | 0.0056 | 0.1029 | 0.0262 | 0.1587 | 0.0586 | 0.1640 | 0.0586 | 0.1722 | 0.0873 | 0.3583 | 0.7630 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0014 | 0.0006 | 0.0122 | 0.0029 | 0.0480 | 0.0161 | 0.0735 | 0.0365 | 0.0724 | 0.0276 | 0.0882 | 0.0419 | 0.7031 | 0.8745 | 0.0056 | 0.0041 | 0.0014 | 0.0331 | 0.0324 | 0.0455 | 0.0606 | 0.0909 | 0.1437 | 0.2066 | 0.1521 | 0.1901 | 0.1211 | 0.1116 | 0.1563 | 0.1570 | 0.3268 | 0.1612 | 0.0006 | 0.0041 | 0.0094 | 0.0241 | 0.0700 | 0.1329 | 0.0988 | 0.1424 | 0.5176 | 5 | 6 | 6 | 8 | 9 | 10 | 14 | 28 | 84 | 0.2835 | 3.77 | 2.562 | 0.7553 | 7069.4 | 2850000 | 1600000000 | 1100000000000 | 0.6411 | 0.0755 | 0.0751 | 0.0073 | 0.1503 | 0.0125 | 0.2306 | 0.0658 | 0.2098 | 0.1524 | 0.1710 | 0.1994 | 0.0984 | 0.1754 | 0.0492 | 0.1242 | 0.0130 | 0.1420 | 0.0026 | 0.1211 | 0.0063 | 0.0020 | 0.0073 | 0.0041 | 0.0078 | 0.0138 | 0.0195 | 0.0292 | 0.0640 | 0.0604 | 0.0762 | 0.0835 | 0.0703 | 0.0722 | 0.0996 | 0.1078 | 0.6489 | 0.6271 | 0.0012 | 0.0040 | 0.0030 | 0.0020 | 0.0084 | 0.0080 | 0.0247 | 0.0172 | 0.0596 | 0.0669 | 0.0915 | 0.0948 | 0.0686 | 0.0749 | 0.1113 | 0.1021 | 0.6318 | 0.6302 | 0.0027 | 0.0027 | 0.0092 | 0.0223 | 0.0566 | 0.0886 | 0.0691 | 0.1033 | 0.6455 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 153 | 139 | | 5758 | 11802 | 360.4 | 40.57 | 302.04 | 287.41 | 307 | 326 | 339 | 350 | 361 | 372 | 383 | 396 | 412 | 0.0835 | 986 | 0.859 | 110.32 | 27.29 | 1 | 0.0455 | 262 | 0.0019 | 22.05 | 6.508 | 0.2365 | 131562.0 | 48600000 | 18200000000 | 6860000000000 | 0.4593 | 0.1900 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0000 | 0.0030 | 0.0002 | 0.0199 | 0.0116 | 0.0345 | 0.0200 | 0.0450 | 0.0106 | 0.0849 | 0.0181 | 0.8109 | 0.9396 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0002 | 0.0165 | 0.0116 | 0.0244 | 0.0200 | 0.0244 | 0.0106 | 0.0400 | 0.0181 | 0.8916 | 0.9396 | 0.0419 | 0.0000 | 0.1204 | 0.0000 | 0.1414 | 0.0000 | 0.1204 | 0.0000 | 0.0942 | 0.0000 | 0.1204 | 0.0000 | 0.1099 | 0.0000 | 0.1099 | 0.0000 | 0.1414 | 0.0000 | 0.0027 | 0.0030 | 0.0172 | 0.0320 | 0.0573 | 0.1004 | 0.1018 | 0.1375 | 0.5480 | 23 | 35 | 59 | 111 | 207 | 327 | 442 | 575 | 737 | 0.0095 | 68.30 | 6.730 | 0.3226 | 173824.0 | 123000000 | 98700000000 | 86100000000000 | 0.4300 | 0.1996 | 0.0309 | 0.0016 | 0.1561 | 0.0094 | 0.2346 | 0.0661 | 0.1920 | 0.1351 | 0.1669 | 0.2033 | 0.1068 | 0.2090 | 0.0576 | 0.1286 | 0.0434 | 0.1167 | 0.0117 | 0.1302 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0011 | 0.0013 | 0.0078 | 0.0063 | 0.0446 | 0.0401 | 0.0822 | 0.0683 | 0.0522 | 0.0435 | 0.0816 | 0.0691 | 0.7299 | 0.7711 | 0.0005 | 0.0003 | 0.0007 | 0.0019 | 0.0032 | 0.0051 | 0.0178 | 0.0177 | 0.0597 | 0.0756 | 0.1097 | 0.1293 | 0.0834 | 0.0942 | 0.1134 | 0.1322 | 0.6116 | 0.5437 | 0.0000 | 0.0002 | 0.0008 | 0.0107 | 0.0530 | 0.0945 | 0.0643 | 0.1014 | 0.6751 |
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1207 | 207 | | 6980 | 19624 | 335.7 | 74.32 | 299.24 | 411.18 | 218 | 282 | 315 | 337 | 355 | 370 | 382 | 395 | 412 | 0.0495 | 972 | 0.878 | 105.01 | 22.67 | 2 | 0.0338 | 236 | 0.0016 | 18.87 | 6.802 | 0.2595 | 118201.0 | 43000000 | 16000000000 | 6030000000000 | 0.3992 | 0.2312 | 0.0008 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0000 | 0.0151 | 0.0005 | 0.0362 | 0.0109 | 0.0496 | 0.0198 | 0.0603 | 0.0114 | 0.1042 | 0.0181 | 0.7262 | 0.9392 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0005 | 0.0117 | 0.0106 | 0.0200 | 0.0197 | 0.0164 | 0.0105 | 0.0219 | 0.0154 | 0.9264 | 0.9434 | 0.0234 | 0.1429 | 0.0263 | 0.0000 | 0.0536 | 0.4286 | 0.0623 | 0.2857 | 0.0837 | 0.1429 | 0.1003 | 0.0000 | 0.1120 | 0.0000 | 0.1324 | 0.0000 | 0.4060 | 0.0000 | 0.0007 | 0.0016 | 0.0028 | 0.0094 | 0.0211 | 0.0392 | 0.0446 | 0.0634 | 0.8170 | 12 | 16 | 20 | 28 | 78 | 180 | 350 | 599 | 943 | 0.0721 | 64.70 | 5.520 | 0.4930 | 258610.0 | 294000000 | 385000000000 | 559000000000000 | 0.4020 | 0.2305 | 0.0543 | 0.0023 | 0.2124 | 0.0098 | 0.3077 | 0.0976 | 0.1647 | 0.1574 | 0.1179 | 0.2237 | 0.0828 | 0.2003 | 0.0326 | 0.1140 | 0.0217 | 0.0910 | 0.0059 | 0.1039 | 0.0003 | 0.0000 | 0.0001 | 0.0001 | 0.0013 | 0.0004 | 0.0073 | 0.0059 | 0.0473 | 0.0415 | 0.0872 | 0.0708 | 0.0574 | 0.0514 | 0.0844 | 0.0737 | 0.7147 | 0.7561 | 0.0003 | 0.0002 | 0.0014 | 0.0008 | 0.0026 | 0.0025 | 0.0115 | 0.0140 | 0.0574 | 0.0661 | 0.1058 | 0.1190 | 0.0739 | 0.0814 | 0.1015 | 0.1092 | 0.6456 | 0.6068 | 0.0002 | 0.0005 | 0.0011 | 0.0070 | 0.0580 | 0.0920 | 0.0640 | 0.0926 | 0.6846 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 683 | 505 | | 9600 | 13298 | 347.1 | 90.75 | 319.79 | 439.11 | 246 | 274 | 294 | 312 | 332 | 353 | 381 | 416 | 470 | 0.0782 | 1040 | 0.961 | 166.08 | 57.22 | 7 | 0.0454 | 436 | 0.0006 | 69.61 | 7.648 | 0.1494 | 128725.0 | 51000000 | 21600000000 | 9760000000000 | 0.4152 | 0.2290 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0044 | 0.0001 | 0.0190 | 0.0018 | 0.0789 | 0.0210 | 0.1597 | 0.0534 | 0.1464 | 0.0539 | 0.1647 | 0.0695 | 0.4253 | 0.8003 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0000 | 0.0072 | 0.0008 | 0.0324 | 0.0123 | 0.0692 | 0.0280 | 0.0621 | 0.0217 | 0.0867 | 0.0317 | 0.7404 | 0.9055 | 0.0011 | 0.0013 | 0.0042 | 0.0116 | 0.0116 | 0.0142 | 0.0563 | 0.0927 | 0.1216 | 0.1660 | 0.1689 | 0.1789 | 0.1068 | 0.1042 | 0.1474 | 0.1416 | 0.3821 | 0.2896 | 0.0019 | 0.0036 | 0.0075 | 0.0278 | 0.0824 | 0.1264 | 0.0993 | 0.1177 | 0.5333 | 8 | 11 | 19 | 48 | 133 | 237 | 381 | 574 | 904 | 0.0562 | 65.50 | 5.773 | 0.4645 | 295068.0 | 395000000 | 660000000000 | 1.28E+15 | 0.5123 | 0.1612 | 0.0285 | 0.0008 | 0.1068 | 0.0100 | 0.2304 | 0.0455 | 0.1628 | 0.1039 | 0.1575 | 0.1882 | 0.1495 | 0.1902 | 0.0730 | 0.1302 | 0.0525 | 0.1448 | 0.0391 | 0.1865 | 0.0000 | 0.0000 | 0.0004 | 0.0007 | 0.0014 | 0.0009 | 0.0073 | 0.0049 | 0.0456 | 0.0385 | 0.0721 | 0.0610 | 0.0536 | 0.0421 | 0.0776 | 0.0731 | 0.7421 | 0.7787 | 0.0003 | 0.0009 | 0.0008 | 0.0017 | 0.0015 | 0.0020 | 0.0134 | 0.0187 | 0.0628 | 0.0715 | 0.0953 | 0.1049 | 0.0630 | 0.0729 | 0.0985 | 0.1136 | 0.6646 | 0.6137 | 0.0002 | 0.0011 | 0.0013 | 0.0095 | 0.0546 | 0.0888 | 0.0517 | 0.0893 | 0.7034 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1208 | 205 | | 6928 | 22071 | 341.7 | 78.65 | 108.42 | 121.55 | 242 | 273 | 297 | 318 | 338 | 358 | 381 | 406 | 444 | 0.0464 | 1025 | 0.821 | 127.02 | 32.56 | 1 | 0.0485 | 336 | 0.0010 | 44.29 | 7.174 | 0.1864 | 122938.0 | 46400000 | 18300000000 | 7530000000000 | 0.4442 | 0.2150 | 0.0005 | 0.0000 | 0.0009 | 0.0002 | 0.0054 | 0.0000 | 0.0289 | 0.0006 | 0.0774 | 0.0196 | 0.1548 | 0.0468 | 0.1496 | 0.0486 | 0.1733 | 0.0699 | 0.4092 | 0.8144 | 0.0002 | 0.0000 | 0.0004 | 0.0001 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0331 | 0.0134 | 0.0668 | 0.0319 | 0.0580 | 0.0246 | 0.0875 | 0.0358 | 0.7479 | 0.8940 | 0.0023 | 0.0124 | 0.0062 | 0.0155 | 0.0247 | 0.0310 | 0.0918 | 0.1455 | 0.1550 | 0.2012 | 0.1958 | 0.1827 | 0.1210 | 0.1022 | 0.1365 | 0.1269 | 0.2668 | 0.1827 | 0.0003 | 0.0015 | 0.0063 | 0.0271 | 0.0855 | 0.1353 | 0.1139 | 0.1317 | 0.4984 | 9 | 13 | 22 | 40 | 63 | 94 | 133 | 188 | 275 | 0.0306 | 13.52 | 5.344 | 0.4677 | 26526.8 | 9310000 | 4040000000 | 2020000000000 | 0.4133 | 0.2398 | 0.0339 | 0.0012 | 0.1396 | 0.0060 | 0.2401 | 0.0523 | 0.1953 | 0.1264 | 0.1400 | 0.1867 | 0.1291 | 0.2003 | 0.0747 | 0.1544 | 0.0331 | 0.1250 | 0.0141 | 0.1478 | 0.0006 | 0.0003 | 0.0014 | 0.0015 | 0.0028 | 0.0033 | 0.0161 | 0.0120 | 0.0537 | 0.0500 | 0.0941 | 0.0727 | 0.0729 | 0.0606 | 0.1043 | 0.0889 | 0.6540 | 0.7107 | 0.0007 | 0.0010 | 0.0031 | 0.0019 | 0.0047 | 0.0087 | 0.0232 | 0.0267 | 0.0849 | 0.0952 | 0.1181 | 0.1316 | 0.0860 | 0.0864 | 0.1223 | 0.1332 | 0.5570 | 0.5153 | 0.0002 | 0.0019 | 0.0039 | 0.0193 | 0.0666 | 0.1098 | 0.0796 | 0.1117 | 0.6070 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1026 | 526 | | 1774 | 10377 | 333.7 | 82.77 | 7.07 | 6.95 | 228 | 252 | 275 | 299 | 328 | 356 | 381 | 404 | 456 | 0.0754 | 782 | 1.019 | 63.03 | 17.72 | 1 | 0.0902 | 160 | 0.0074 | 2.20 | 5.116 | 0.5219 | 118176.0 | 44200000 | 17400000000 | 7100000000000 | 0.3704 | 0.2523 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0044 | 0.0018 | 0.0196 | 0.0031 | 0.0480 | 0.0270 | 0.0981 | 0.0590 | 0.0960 | 0.0277 | 0.1156 | 0.0522 | 0.6161 | 0.8291 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0006 | 0.0077 | 0.0006 | 0.0216 | 0.0198 | 0.0448 | 0.0475 | 0.0309 | 0.0158 | 0.0394 | 0.0300 | 0.8533 | 0.8858 | 0.0000 | 0.0070 | 0.0026 | 0.0000 | 0.0159 | 0.0211 | 0.0265 | 0.0493 | 0.0688 | 0.0563 | 0.0688 | 0.0634 | 0.0794 | 0.1197 | 0.0926 | 0.1127 | 0.6455 | 0.5704 | 0.0000 | 0.0012 | 0.0035 | 0.0106 | 0.0307 | 0.0507 | 0.0460 | 0.0507 | 0.8066 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.0683 | 0.36 | 0.960 | 0.2803 | 98.4 | 3645.61 | 211535 | 13700000 | 0.5870 | 0.1077 | 0.0219 | 0.0000 | 0.0918 | 0.0034 | 0.2036 | 0.0218 | 0.2478 | 0.0615 | 0.2315 | 0.1441 | 0.1344 | 0.2346 | 0.0524 | 0.2632 | 0.0151 | 0.1992 | 0.0014 | 0.0723 | 0.0070 | 0.0001 | 0.0372 | 0.0017 | 0.1009 | 0.0115 | 0.1433 | 0.0351 | 0.1866 | 0.1006 | 0.1797 | 0.1701 | 0.1357 | 0.2256 | 0.0991 | 0.2326 | 0.1105 | 0.2226 | 0.2165 | 0.2377 | 0.1957 | 0.1575 | 0.1447 | 0.1137 | 0.0919 | 0.0699 | 0.0705 | 0.0657 | 0.0566 | 0.0428 | 0.0334 | 0.0323 | 0.0340 | 0.0396 | 0.1567 | 0.2409 | 0.0252 | 0.0972 | 0.1538 | 0.1674 | 0.1709 | 0.1299 | 0.1019 | 0.0664 | 0.0874 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1191 | 273 | | 5225 | 11025 | 340.7 | 62.23 | 307.66 | 490.68 | 248 | 283 | 309 | 330 | 349 | 367 | 381 | 396 | 416 | 0.0786 | 867 | 0.925 | 79.06 | 24.04 | 4 | 0.0404 | 211 | 0.0014 | 23.53 | 6.846 | 0.2524 | 119949.0 | 43400000 | 16100000000 | 6080000000000 | 0.4363 | 0.2015 | 0.0005 | 0.0000 | 0.0024 | 0.0000 | 0.0052 | 0.0004 | 0.0144 | 0.0012 | 0.0415 | 0.0155 | 0.0735 | 0.0306 | 0.0749 | 0.0196 | 0.1045 | 0.0333 | 0.6830 | 0.8994 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0014 | 0.0004 | 0.0046 | 0.0012 | 0.0191 | 0.0153 | 0.0353 | 0.0304 | 0.0290 | 0.0163 | 0.0376 | 0.0273 | 0.8719 | 0.9093 | 0.0076 | 0.0000 | 0.0291 | 1.0000 | 0.0443 | 0.0000 | 0.0581 | 0.0000 | 0.1407 | 0.0000 | 0.1361 | 0.0000 | 0.1300 | 0.0000 | 0.1529 | 0.0000 | 0.3012 | 0.0000 | 0.0007 | 0.0021 | 0.0070 | 0.0115 | 0.0369 | 0.0518 | 0.0539 | 0.0869 | 0.7493 | 8 | 10 | 12 | 16 | 25 | 61 | 277 | 673 | 1103 | 0.0635 | 24.60 | 4.331 | 0.4441 | 335399.0 | 461000000 | 722000000000 | 1.24E+15 | 0.5061 | 0.1164 | 0.0746 | 0.0000 | 0.2293 | 0.0218 | 0.2541 | 0.1592 | 0.1602 | 0.1687 | 0.1409 | 0.2082 | 0.0829 | 0.1891 | 0.0304 | 0.0898 | 0.0193 | 0.0939 | 0.0083 | 0.0694 | 0.0000 | 0.0000 | 0.0006 | 0.0006 | 0.0038 | 0.0011 | 0.0065 | 0.0047 | 0.0332 | 0.0356 | 0.0632 | 0.0601 | 0.0397 | 0.0361 | 0.0585 | 0.0593 | 0.7947 | 0.8025 | 0.0003 | 0.0003 | 0.0007 | 0.0003 | 0.0023 | 0.0017 | 0.0056 | 0.0055 | 0.0391 | 0.0464 | 0.0687 | 0.0695 | 0.0444 | 0.0488 | 0.0736 | 0.0768 | 0.7653 | 0.7506 | 0.0003 | 0.0012 | 0.0016 | 0.0068 | 0.0346 | 0.0626 | 0.0392 | 0.0688 | 0.7849 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 155 | | 5618 | 13253 | 344.2 | 70.32 | 104.68 | 99.98 | 259 | 282 | 300 | 316 | 333 | 354 | 379 | 407 | 444 | 0.0684 | 907 | 0.910 | 83.20 | 23.02 | 1 | 0.0377 | 212 | 0.0019 | 20.54 | 6.561 | 0.2353 | 123384.0 | 46000000 | 17900000000 | 7180000000000 | 0.3957 | 0.2470 | 0.0003 | 0.0000 | 0.0008 | 0.0002 | 0.0063 | 0.0002 | 0.0181 | 0.0011 | 0.0550 | 0.0161 | 0.1125 | 0.0345 | 0.1341 | 0.0319 | 0.1675 | 0.0521 | 0.5055 | 0.8638 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0000 | 0.0071 | 0.0002 | 0.0199 | 0.0120 | 0.0402 | 0.0218 | 0.0557 | 0.0130 | 0.0771 | 0.0230 | 0.7960 | 0.9301 | 0.0029 | 0.0140 | 0.0069 | 0.0421 | 0.0255 | 0.0514 | 0.0609 | 0.1495 | 0.1159 | 0.1822 | 0.1906 | 0.1869 | 0.1375 | 0.1122 | 0.1503 | 0.1075 | 0.3094 | 0.1542 | 0.0020 | 0.0024 | 0.0071 | 0.0256 | 0.0643 | 0.1057 | 0.0923 | 0.1179 | 0.5826 | 14 | 27 | 43 | 59 | 75 | 94 | 119 | 159 | 237 | 0.0186 | 8.63 | 5.042 | 0.5074 | 20954.6 | 6170000 | 2290000000 | 982000000000 | 0.4377 | 0.2064 | 0.0105 | 0.0017 | 0.0659 | 0.0063 | 0.1467 | 0.0244 | 0.1714 | 0.0701 | 0.1841 | 0.1287 | 0.1586 | 0.1670 | 0.1270 | 0.1575 | 0.0857 | 0.1608 | 0.0501 | 0.2834 | 0.0010 | 0.0010 | 0.0042 | 0.0013 | 0.0055 | 0.0034 | 0.0205 | 0.0174 | 0.0627 | 0.0477 | 0.0920 | 0.0753 | 0.0818 | 0.0727 | 0.1040 | 0.0953 | 0.6284 | 0.6859 | 0.0011 | 0.0027 | 0.0038 | 0.0036 | 0.0089 | 0.0103 | 0.0277 | 0.0262 | 0.0728 | 0.0839 | 0.1098 | 0.1194 | 0.0899 | 0.0902 | 0.1106 | 0.1154 | 0.5756 | 0.5484 | 0.0011 | 0.0045 | 0.0087 | 0.0268 | 0.0665 | 0.1035 | 0.0854 | 0.1079 | 0.5957 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1161 | 623 | | 4896 | 12890 | 292.1 | 122.93 | 77.58 | 156.83 | 140 | 170 | 195 | 234 | 275 | 322 | 378 | 426 | 471 | 0.0714 | 920 | 0.771 | 63.56 | 16.03 | 4 | 0.0327 | 160 | 0.0010 | 16.01 | 7.132 | 0.2695 | 100453.0 | 38700000 | 16000000000 | 6940000000000 | 0.3486 | 0.2680 | 0.0008 | 0.0004 | 0.0008 | 0.0015 | 0.0008 | 0.0030 | 0.0194 | 0.0109 | 0.0891 | 0.0449 | 0.1336 | 0.0612 | 0.1263 | 0.0581 | 0.1571 | 0.0849 | 0.4721 | 0.7350 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0003 | 0.0018 | 0.0061 | 0.0047 | 0.0187 | 0.0171 | 0.0224 | 0.0237 | 0.0252 | 0.0179 | 0.0330 | 0.0339 | 0.8936 | 0.9006 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0053 | 0.0087 | 0.0381 | 0.0582 | 0.0545 | 0.0582 | 0.0393 | 0.0616 | 0.0527 | 0.0851 | 0.8102 | 0.7240 | 0.0000 | 0.0004 | 0.0009 | 0.0035 | 0.0274 | 0.0363 | 0.0314 | 0.0456 | 0.8544 | 7 | 9 | 11 | 13 | 17 | 25 | 42 | 84 | 223 | 0.1061 | 17.09 | 3.929 | 0.6640 | 30613.2 | 21000000 | 18400000000 | 18500000000000 | 0.3956 | 0.2278 | 0.0335 | 0.0066 | 0.0911 | 0.0183 | 0.1580 | 0.0374 | 0.2026 | 0.0682 | 0.2286 | 0.1364 | 0.1283 | 0.1540 | 0.1022 | 0.1393 | 0.0353 | 0.1598 | 0.0204 | 0.2801 | 0.0027 | 0.0025 | 0.0047 | 0.0030 | 0.0047 | 0.0050 | 0.0097 | 0.0116 | 0.0484 | 0.0449 | 0.0684 | 0.0581 | 0.0494 | 0.0512 | 0.0735 | 0.0722 | 0.7386 | 0.7516 | 0.0004 | 0.0009 | 0.0004 | 0.0004 | 0.0033 | 0.0035 | 0.0114 | 0.0097 | 0.0521 | 0.0578 | 0.0720 | 0.0843 | 0.0606 | 0.0618 | 0.0781 | 0.0856 | 0.7216 | 0.6961 | 0.0004 | 0.0011 | 0.0026 | 0.0086 | 0.0474 | 0.0784 | 0.0523 | 0.0732 | 0.7359 |