High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 504 | 454 | 4632 | 9949 | 526.7 | 103.94 | 144.23 | 161.03 | 403 | 434 | 461 | 488 | 517 | 541 | 573 | 613 | 674 | 0.0767 | 763 | 1.167 | 101.13 | 34.54 | 1 | 0.0531 | 246 | 0.0009 | 55.30 | 7.231 | 0.1624 | 288245.0 | 164000000 | 96700000000 | 59100000000000 | 0.4365 | 0.2052 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0095 | 0.0004 | 0.0653 | 0.0181 | 0.1242 | 0.0349 | 0.1378 | 0.0329 | 0.1714 | 0.0511 | 0.4897 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0044 | 0.0002 | 0.0279 | 0.0136 | 0.0541 | 0.0242 | 0.0597 | 0.0141 | 0.0859 | 0.0249 | 0.7668 | 0.9230 | 0.0054 | 0.0188 | 0.0054 | 0.0125 | 0.0201 | 0.0313 | 0.0698 | 0.1438 | 0.1557 | 0.2438 | 0.1906 | 0.1750 | 0.1302 | 0.1188 | 0.1664 | 0.1563 | 0.2564 | 0.1000 | 0.0009 | 0.0038 | 0.0033 | 0.0302 | 0.0797 | 0.1282 | 0.1249 | 0.1556 | 0.4734 | 18 | 28 | 46 | 67 | 93 | 124 | 163 | 220 | 330 | 0.0156 | 19.65 | 5.459 | 0.4608 | 46729.0 | 24700000 | 17300000000 | 14400000000000 | 0.5530 | 0.1302 | 0.0176 | 0.0010 | 0.1067 | 0.0100 | 0.2360 | 0.0424 | 0.1854 | 0.0883 | 0.1601 | 0.1621 | 0.1292 | 0.2014 | 0.0730 | 0.1717 | 0.0597 | 0.1438 | 0.0323 | 0.1793 | 0.0002 | 0.0000 | 0.0009 | 0.0012 | 0.0024 | 0.0019 | 0.0176 | 0.0129 | 0.0691 | 0.0574 | 0.1203 | 0.0945 | 0.0888 | 0.0781 | 0.1108 | 0.1107 | 0.5899 | 0.6432 | 0.0004 | 0.0009 | 0.0011 | 0.0022 | 0.0061 | 0.0106 | 0.0301 | 0.0396 | 0.1050 | 0.1091 | 0.1384 | 0.1552 | 0.0986 | 0.0994 | 0.1376 | 0.1271 | 0.4828 | 0.4560 | 0.0017 | 0.0012 | 0.0043 | 0.0240 | 0.0822 | 0.1343 | 0.0909 | 0.1308 | 0.5305 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 463 | 730 | 6826 | 14133 | 120.4 | 23.00 | 116.76 | 79.84 | 93 | 102 | 108 | 113 | 119 | 124 | 130 | 137 | 150 | 0.0723 | 1022 | 1.085 | 103.16 | 28.18 | 1 | 0.0349 | 238 | 0.0037 | 11.96 | 5.947 | 0.3160 | 15021.5 | 1940000 | 260000000 | 36200000000 | 0.4335 | 0.2237 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0044 | 0.0009 | 0.0154 | 0.0017 | 0.0519 | 0.0164 | 0.0996 | 0.0314 | 0.1171 | 0.0321 | 0.1581 | 0.0575 | 0.5524 | 0.8598 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0003 | 0.0060 | 0.0004 | 0.0250 | 0.0105 | 0.0473 | 0.0218 | 0.0483 | 0.0136 | 0.0723 | 0.0276 | 0.7998 | 0.9258 | 0.0111 | 0.0195 | 0.0101 | 0.0469 | 0.0364 | 0.0703 | 0.1083 | 0.1367 | 0.1447 | 0.1680 | 0.1903 | 0.1992 | 0.1326 | 0.0977 | 0.1164 | 0.1094 | 0.2500 | 0.1523 | 0.0021 | 0.0061 | 0.0177 | 0.0360 | 0.0903 | 0.1196 | 0.1114 | 0.1422 | 0.4745 | 27 | 44 | 61 | 81 | 101 | 124 | 151 | 182 | 227 | 0.0032 | 25.81 | 6.449 | 0.3268 | 20005.6 | 4300000 | 1080000000 | 305000000000 | 0.5926 | 0.1078 | 0.0158 | 0.0022 | 0.1055 | 0.0083 | 0.2116 | 0.0336 | 0.1858 | 0.0797 | 0.1786 | 0.1495 | 0.1481 | 0.2016 | 0.0911 | 0.1603 | 0.0466 | 0.1718 | 0.0169 | 0.1931 | 0.0011 | 0.0005 | 0.0019 | 0.0017 | 0.0046 | 0.0033 | 0.0183 | 0.0093 | 0.0620 | 0.0454 | 0.1196 | 0.0892 | 0.1019 | 0.0765 | 0.1366 | 0.1110 | 0.5541 | 0.6630 | 0.0017 | 0.0050 | 0.0065 | 0.0107 | 0.0178 | 0.0259 | 0.0421 | 0.0517 | 0.1004 | 0.1214 | 0.1658 | 0.1753 | 0.1211 | 0.1343 | 0.1429 | 0.1473 | 0.4017 | 0.3284 | 0.0007 | 0.0028 | 0.0097 | 0.0328 | 0.0821 | 0.1460 | 0.1176 | 0.1387 | 0.4696 | |||
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 462 | 6757 | 10694 | 103.6 | 26.81 | 127.16 | 113.08 | 75 | 82 | 88 | 93 | 98 | 104 | 112 | 123 | 140 | 0.0902 | 965 | 1.167 | 103.82 | 31.40 | 1 | 0.0364 | 246 | 0.0039 | 11.91 | 5.964 | 0.3215 | 11459.3 | 1360000 | 172000000 | 23500000000 | 0.4214 | 0.2299 | 0.0010 | 0.0000 | 0.0030 | 0.0000 | 0.0088 | 0.0010 | 0.0340 | 0.0029 | 0.0862 | 0.0218 | 0.1582 | 0.0506 | 0.1512 | 0.0465 | 0.1907 | 0.0759 | 0.3668 | 0.8013 | 0.0006 | 0.0000 | 0.0013 | 0.0000 | 0.0044 | 0.0003 | 0.0169 | 0.0005 | 0.0417 | 0.0128 | 0.0730 | 0.0254 | 0.0763 | 0.0197 | 0.1012 | 0.0369 | 0.6846 | 0.9045 | 0.0039 | 0.0036 | 0.0093 | 0.0000 | 0.0171 | 0.0342 | 0.0497 | 0.0739 | 0.0994 | 0.1586 | 0.1654 | 0.2036 | 0.1165 | 0.1243 | 0.1405 | 0.1333 | 0.3983 | 0.2685 | 0.0040 | 0.0058 | 0.0112 | 0.0426 | 0.0834 | 0.1119 | 0.0888 | 0.1241 | 0.5283 | 17 | 32 | 49 | 71 | 97 | 124 | 158 | 204 | 276 | 0.0049 | 28.88 | 6.477 | 0.3379 | 28954.2 | 9110000 | 3510000000 | 1540000000000 | 0.5010 | 0.1908 | 0.0104 | 0.0014 | 0.0825 | 0.0080 | 0.1622 | 0.0280 | 0.1715 | 0.0704 | 0.1802 | 0.1431 | 0.1846 | 0.1949 | 0.0978 | 0.1574 | 0.0672 | 0.1528 | 0.0437 | 0.2441 | 0.0002 | 0.0005 | 0.0006 | 0.0006 | 0.0043 | 0.0027 | 0.0166 | 0.0116 | 0.0621 | 0.0488 | 0.1025 | 0.0778 | 0.0847 | 0.0716 | 0.1177 | 0.0936 | 0.6114 | 0.6925 | 0.0027 | 0.0022 | 0.0036 | 0.0056 | 0.0141 | 0.0086 | 0.0335 | 0.0365 | 0.0847 | 0.0941 | 0.1182 | 0.1391 | 0.0972 | 0.0926 | 0.1152 | 0.1183 | 0.5308 | 0.5030 | 0.0007 | 0.0021 | 0.0060 | 0.0293 | 0.0767 | 0.1199 | 0.0870 | 0.1146 | 0.5636 | |||
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 364 | 5225 | 12570 | 114.6 | 29.24 | 148.81 | 175.19 | 84 | 92 | 98 | 104 | 110 | 116 | 124 | 134 | 151 | 0.0699 | 879 | 0.810 | 72.24 | 18.44 | 1 | 0.0389 | 203 | 0.0030 | 17.44 | 6.162 | 0.2786 | 13983.3 | 1830000 | 261000000 | 40800000000 | 0.4284 | 0.2226 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0091 | 0.0002 | 0.0324 | 0.0035 | 0.0800 | 0.0215 | 0.1378 | 0.0503 | 0.1584 | 0.0530 | 0.2021 | 0.0722 | 0.3790 | 0.7993 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0024 | 0.0000 | 0.0124 | 0.0006 | 0.0398 | 0.0144 | 0.0640 | 0.0290 | 0.0688 | 0.0226 | 0.1076 | 0.0342 | 0.7040 | 0.8992 | 0.0056 | 0.0087 | 0.0111 | 0.0173 | 0.0356 | 0.0376 | 0.0934 | 0.1272 | 0.1446 | 0.1821 | 0.1758 | 0.1792 | 0.1224 | 0.1098 | 0.1313 | 0.1156 | 0.2803 | 0.2225 | 0.0027 | 0.0045 | 0.0145 | 0.0377 | 0.0921 | 0.1403 | 0.1135 | 0.1589 | 0.4358 | 11 | 15 | 26 | 46 | 79 | 124 | 182 | 256 | 391 | 0.0134 | 67.23 | 6.423 | 0.3671 | 52832.2 | 26600000 | 16100000000 | 11000000000000 | 0.5002 | 0.1902 | 0.0463 | 0.0026 | 0.1259 | 0.0198 | 0.2117 | 0.0847 | 0.1593 | 0.1067 | 0.1464 | 0.1418 | 0.1017 | 0.1687 | 0.1017 | 0.1354 | 0.0637 | 0.1313 | 0.0432 | 0.2090 | 0.0002 | 0.0000 | 0.0006 | 0.0005 | 0.0035 | 0.0017 | 0.0186 | 0.0129 | 0.0574 | 0.0525 | 0.0893 | 0.0815 | 0.0763 | 0.0603 | 0.1007 | 0.0887 | 0.6535 | 0.7020 | 0.0005 | 0.0012 | 0.0052 | 0.0030 | 0.0073 | 0.0094 | 0.0250 | 0.0301 | 0.0725 | 0.0779 | 0.1207 | 0.1181 | 0.0816 | 0.0907 | 0.1035 | 0.1026 | 0.5837 | 0.5670 | 0.0000 | 0.0011 | 0.0045 | 0.0194 | 0.0690 | 0.1067 | 0.0853 | 0.1053 | 0.6087 | |||
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1250 | 480 | 6010 | 16284 | 271.9 | 68.74 | 353.07 | 523.57 | 175 | 224 | 245 | 264 | 279 | 293 | 309 | 328 | 354 | 0.0591 | 962 | 1.159 | 131.22 | 44.78 | 2 | 0.0542 | 326 | 0.0013 | 30.49 | 7.001 | 0.2258 | 78643.6 | 23800000 | 7440000000 | 2400000000000 | 0.4018 | 0.2328 | 0.0008 | 0.0000 | 0.0022 | 0.0004 | 0.0030 | 0.0013 | 0.0170 | 0.0019 | 0.0460 | 0.0171 | 0.0930 | 0.0344 | 0.1038 | 0.0340 | 0.1408 | 0.0511 | 0.5934 | 0.8598 | 0.0002 | 0.0000 | 0.0002 | 0.0002 | 0.0002 | 0.0005 | 0.0026 | 0.0011 | 0.0142 | 0.0116 | 0.0318 | 0.0207 | 0.0259 | 0.0136 | 0.0451 | 0.0223 | 0.8798 | 0.9300 | 0.0040 | 0.0119 | 0.0161 | 0.0357 | 0.0185 | 0.0238 | 0.0611 | 0.1111 | 0.0957 | 0.1905 | 0.1262 | 0.1905 | 0.1294 | 0.1349 | 0.1455 | 0.1706 | 0.4035 | 0.1310 | 0.0006 | 0.0009 | 0.0061 | 0.0148 | 0.0439 | 0.0742 | 0.0805 | 0.1147 | 0.6642 | 9 | 12 | 15 | 20 | 33 | 124 | 394 | 769 | 1226 | 0.0716 | 108.75 | 5.493 | 0.4880 | 398768.0 | 556000000 | 859000000000 | 1.42E+15 | 0.4180 | 0.2363 | 0.0593 | 0.0007 | 0.2062 | 0.0235 | 0.3032 | 0.1478 | 0.1442 | 0.1457 | 0.1078 | 0.1974 | 0.0876 | 0.1807 | 0.0499 | 0.1175 | 0.0337 | 0.0960 | 0.0081 | 0.0907 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0016 | 0.0009 | 0.0066 | 0.0043 | 0.0421 | 0.0372 | 0.0706 | 0.0656 | 0.0492 | 0.0439 | 0.0706 | 0.0630 | 0.7590 | 0.7848 | 0.0002 | 0.0002 | 0.0019 | 0.0018 | 0.0028 | 0.0030 | 0.0118 | 0.0149 | 0.0476 | 0.0557 | 0.0800 | 0.0896 | 0.0607 | 0.0667 | 0.0891 | 0.0875 | 0.7059 | 0.6807 | 0.0004 | 0.0010 | 0.0028 | 0.0079 | 0.0436 | 0.0772 | 0.0515 | 0.0798 | 0.7360 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1021 | 289 | 15480 | 20962 | 107.9 | 32.54 | 126.87 | 115.24 | 70 | 80 | 88 | 96 | 104 | 112 | 122 | 133 | 151 | 0.0665 | 1394 | 1.246 | 41.87 | 18.36 | 4 | 0.0075 | 116 | 0.0011 | 32.98 | 7.115 | 0.2122 | 12708.7 | 1630000 | 225000000 | 33600000000 | 0.4430 | 0.2071 | 0.0021 | 0.0002 | 0.0042 | 0.0005 | 0.0146 | 0.0012 | 0.0424 | 0.0071 | 0.1092 | 0.0273 | 0.1709 | 0.0639 | 0.1595 | 0.0673 | 0.1788 | 0.1076 | 0.3183 | 0.7248 | 0.0014 | 0.0002 | 0.0020 | 0.0003 | 0.0039 | 0.0009 | 0.0118 | 0.0037 | 0.0393 | 0.0149 | 0.0650 | 0.0333 | 0.0601 | 0.0290 | 0.0876 | 0.0504 | 0.7289 | 0.8672 | 0.0025 | 0.0080 | 0.0037 | 0.0173 | 0.0202 | 0.0306 | 0.0567 | 0.0766 | 0.1110 | 0.1671 | 0.1514 | 0.1598 | 0.1194 | 0.1152 | 0.1455 | 0.1418 | 0.3896 | 0.2836 | 0.0011 | 0.0021 | 0.0090 | 0.0274 | 0.0627 | 0.1065 | 0.0944 | 0.1225 | 0.5742 | 16 | 27 | 45 | 67 | 94 | 124 | 161 | 212 | 289 | 0.0159 | 8.96 | 5.332 | 0.5036 | 29376.6 | 9390000 | 3750000000 | 1790000000000 | 0.4948 | 0.1572 | 0.0112 | 0.0016 | 0.0613 | 0.0068 | 0.1433 | 0.0245 | 0.1682 | 0.0618 | 0.1919 | 0.1370 | 0.1645 | 0.1771 | 0.1051 | 0.1416 | 0.0836 | 0.1568 | 0.0709 | 0.2928 | 0.0008 | 0.0004 | 0.0011 | 0.0016 | 0.0035 | 0.0026 | 0.0133 | 0.0076 | 0.0489 | 0.0371 | 0.0788 | 0.0577 | 0.0640 | 0.0520 | 0.0930 | 0.0767 | 0.6966 | 0.7643 | 0.0006 | 0.0013 | 0.0028 | 0.0020 | 0.0070 | 0.0071 | 0.0249 | 0.0329 | 0.0705 | 0.0821 | 0.1139 | 0.1305 | 0.0891 | 0.1028 | 0.1163 | 0.1349 | 0.5748 | 0.5065 | 0.0001 | 0.0018 | 0.0055 | 0.0186 | 0.0602 | 0.0898 | 0.0819 | 0.1099 | 0.6321 | |
MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 560 | 270 | 5568 | 18268 | 433.5 | 92.93 | 137.20 | 136.94 | 324 | 352 | 376 | 397 | 422 | 446 | 477 | 510 | 564 | 0.0541 | 989 | 1.182 | 95.60 | 36.50 | 1 | 0.0449 | 250 | 0.0012 | 33.93 | 7.010 | 0.1946 | 196527.0 | 93100000 | 46100000000 | 23700000000000 | 0.4332 | 0.2136 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0020 | 0.0002 | 0.0140 | 0.0011 | 0.0717 | 0.0192 | 0.1259 | 0.0400 | 0.1320 | 0.0390 | 0.1664 | 0.0581 | 0.4877 | 0.8422 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0064 | 0.0000 | 0.0304 | 0.0128 | 0.0556 | 0.0229 | 0.0530 | 0.0152 | 0.0754 | 0.0265 | 0.7781 | 0.9225 | 0.0031 | 0.0070 | 0.0071 | 0.0245 | 0.0224 | 0.0280 | 0.0671 | 0.1294 | 0.1180 | 0.1993 | 0.1699 | 0.2133 | 0.1282 | 0.1084 | 0.1506 | 0.1434 | 0.3337 | 0.1469 | 0.0020 | 0.0016 | 0.0052 | 0.0290 | 0.0708 | 0.1225 | 0.0982 | 0.1301 | 0.5406 | 20 | 35 | 55 | 76 | 97 | 124 | 159 | 209 | 290 | 0.0125 | 11.31 | 5.396 | 0.4946 | 37572.9 | 16400000 | 9620000000 | 6730000000000 | 0.5560 | 0.1152 | 0.0139 | 0.0011 | 0.0448 | 0.0071 | 0.1227 | 0.0245 | 0.1370 | 0.0568 | 0.1652 | 0.1234 | 0.1675 | 0.1608 | 0.1217 | 0.1315 | 0.1118 | 0.1516 | 0.1154 | 0.3433 | 0.0013 | 0.0001 | 0.0016 | 0.0026 | 0.0052 | 0.0039 | 0.0169 | 0.0131 | 0.0498 | 0.0475 | 0.0829 | 0.0732 | 0.0663 | 0.0599 | 0.0861 | 0.0802 | 0.6900 | 0.7194 | 0.0015 | 0.0007 | 0.0029 | 0.0034 | 0.0061 | 0.0079 | 0.0209 | 0.0274 | 0.0672 | 0.0758 | 0.1087 | 0.1185 | 0.0846 | 0.0902 | 0.1045 | 0.1152 | 0.6036 | 0.5609 | 0.0021 | 0.0021 | 0.0044 | 0.0190 | 0.0539 | 0.0970 | 0.0768 | 0.0992 | 0.6453 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 412 | 164 | 5214 | 3654 | 127.8 | 31.45 | 127.02 | 119.19 | 94 | 101 | 108 | 114 | 122 | 130 | 140 | 152 | 171 | 0.1992 | 728 | 1.004 | 82.88 | 29.02 | 1 | 0.0410 | 214 | 0.0025 | 19.85 | 6.334 | 0.2553 | 17320.5 | 2500000 | 383000000 | 62600000000 | 0.4259 | 0.2172 | 0.0000 | 0.0000 | 0.0033 | 0.0004 | 0.0102 | 0.0015 | 0.0302 | 0.0023 | 0.0973 | 0.0197 | 0.1795 | 0.0519 | 0.1558 | 0.0471 | 0.1926 | 0.0952 | 0.3310 | 0.7820 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0000 | 0.0154 | 0.0010 | 0.0426 | 0.0123 | 0.0753 | 0.0280 | 0.0688 | 0.0178 | 0.1065 | 0.0382 | 0.6871 | 0.9028 | 0.0040 | 0.0138 | 0.0030 | 0.0165 | 0.0191 | 0.0579 | 0.0702 | 0.1377 | 0.1484 | 0.1791 | 0.1856 | 0.1983 | 0.1414 | 0.1157 | 0.1585 | 0.1267 | 0.2698 | 0.1543 | 0.0013 | 0.0018 | 0.0107 | 0.0360 | 0.0821 | 0.1256 | 0.1087 | 0.1429 | 0.4909 | 21 | 28 | 40 | 58 | 85 | 123 | 162 | 215 | 293 | 0.0076 | 41.14 | 6.126 | 0.3286 | 30335.5 | 10000000 | 4000000000 | 1810000000000 | 0.5437 | 0.1217 | 0.0721 | 0.0000 | 0.1943 | 0.0489 | 0.2183 | 0.0915 | 0.1550 | 0.1362 | 0.1288 | 0.2152 | 0.1070 | 0.2152 | 0.0699 | 0.1060 | 0.0393 | 0.0925 | 0.0153 | 0.0946 | 0.0006 | 0.0000 | 0.0055 | 0.0067 | 0.0079 | 0.0052 | 0.0286 | 0.0202 | 0.0930 | 0.0802 | 0.1471 | 0.1397 | 0.0942 | 0.0874 | 0.1204 | 0.1231 | 0.5027 | 0.5375 | 0.0008 | 0.0031 | 0.0059 | 0.0041 | 0.0110 | 0.0113 | 0.0505 | 0.0515 | 0.1112 | 0.1308 | 0.1457 | 0.1740 | 0.1053 | 0.1174 | 0.1314 | 0.1349 | 0.4381 | 0.3728 | 0.0007 | 0.0049 | 0.0133 | 0.0379 | 0.1011 | 0.1517 | 0.0962 | 0.1187 | 0.4754 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | |||
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 951 | 130 | 6472 | 11634 | 104.2 | 26.74 | 134.36 | 144.55 | 75 | 82 | 88 | 93 | 99 | 106 | 114 | 124 | 140 | 0.0675 | 785 | 1.222 | 77.80 | 31.00 | 1 | 0.0311 | 201 | 0.0033 | 14.98 | 6.074 | 0.2909 | 11575.5 | 1380000 | 176000000 | 24100000000 | 0.4404 | 0.2109 | 0.0008 | 0.0000 | 0.0067 | 0.0000 | 0.0180 | 0.0003 | 0.0355 | 0.0049 | 0.0968 | 0.0225 | 0.1552 | 0.0473 | 0.1791 | 0.0458 | 0.2071 | 0.0729 | 0.3007 | 0.8063 | 0.0002 | 0.0000 | 0.0028 | 0.0000 | 0.0058 | 0.0002 | 0.0154 | 0.0008 | 0.0436 | 0.0128 | 0.0690 | 0.0233 | 0.0790 | 0.0166 | 0.1135 | 0.0378 | 0.6708 | 0.9086 | 0.0078 | 0.0060 | 0.0132 | 0.0302 | 0.0296 | 0.0302 | 0.0685 | 0.0867 | 0.1401 | 0.1512 | 0.1556 | 0.2198 | 0.1222 | 0.1109 | 0.1362 | 0.1431 | 0.3268 | 0.2218 | 0.0014 | 0.0074 | 0.0159 | 0.0337 | 0.0708 | 0.1173 | 0.1045 | 0.1399 | 0.5090 | 11 | 17 | 27 | 47 | 80 | 123 | 170 | 236 | 349 | 0.0095 | 68.36 | 6.495 | 0.3320 | 38946.3 | 15400000 | 7190000000 | 3780000000000 | 0.5106 | 0.1580 | 0.0359 | 0.0011 | 0.1272 | 0.0129 | 0.2289 | 0.0620 | 0.1945 | 0.1073 | 0.1660 | 0.1675 | 0.1137 | 0.2080 | 0.0666 | 0.1442 | 0.0449 | 0.1357 | 0.0224 | 0.1612 | 0.0002 | 0.0000 | 0.0004 | 0.0005 | 0.0036 | 0.0015 | 0.0120 | 0.0079 | 0.0557 | 0.0459 | 0.0946 | 0.0834 | 0.0802 | 0.0594 | 0.1058 | 0.0943 | 0.6476 | 0.7070 | 0.0003 | 0.0013 | 0.0024 | 0.0032 | 0.0089 | 0.0084 | 0.0282 | 0.0316 | 0.0805 | 0.0832 | 0.1194 | 0.1342 | 0.0982 | 0.1048 | 0.1210 | 0.1303 | 0.5413 | 0.5031 | 0.0002 | 0.0014 | 0.0041 | 0.0182 | 0.0668 | 0.1165 | 0.0832 | 0.1178 | 0.5918 | |||
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1057 | 334 | 2802 | 7296 | 92.2 | 25.90 | 117.02 | 76.72 | 61 | 72 | 78 | 83 | 89 | 94 | 102 | 114 | 128 | 0.0968 | 706 | 0.875 | 120.79 | 34.99 | 2 | 0.1071 | 300 | 0.0040 | 10.09 | 5.865 | 0.3358 | 9174.8 | 979929 | 112000000 | 13500000000 | 0.4595 | 0.1918 | 0.0026 | 0.0000 | 0.0019 | 0.0000 | 0.0136 | 0.0034 | 0.0285 | 0.0107 | 0.0783 | 0.0390 | 0.1462 | 0.0642 | 0.1481 | 0.0723 | 0.1708 | 0.0985 | 0.4101 | 0.7119 | 0.0005 | 0.0000 | 0.0009 | 0.0000 | 0.0055 | 0.0027 | 0.0110 | 0.0050 | 0.0375 | 0.0249 | 0.0536 | 0.0345 | 0.0659 | 0.0383 | 0.0893 | 0.0509 | 0.7358 | 0.8437 | 0.0031 | 0.0036 | 0.0047 | 0.0182 | 0.0219 | 0.0400 | 0.0470 | 0.0800 | 0.0799 | 0.1091 | 0.1270 | 0.1564 | 0.0831 | 0.1273 | 0.1191 | 0.1309 | 0.5141 | 0.3345 | 0.0057 | 0.0123 | 0.0188 | 0.0286 | 0.0645 | 0.0989 | 0.0784 | 0.1078 | 0.5850 | 35 | 49 | 64 | 82 | 101 | 122 | 146 | 178 | 225 | 0.0071 | 10.21 | 5.520 | 0.4012 | 19579.1 | 4150000 | 1040000000 | 297000000000 | 0.5233 | 0.1494 | 0.0087 | 0.0019 | 0.0570 | 0.0036 | 0.1531 | 0.0185 | 0.1866 | 0.0588 | 0.2102 | 0.1426 | 0.1618 | 0.1929 | 0.1054 | 0.1643 | 0.0688 | 0.1647 | 0.0484 | 0.2527 | 0.0015 | 0.0006 | 0.0028 | 0.0017 | 0.0081 | 0.0062 | 0.0233 | 0.0159 | 0.0535 | 0.0453 | 0.0933 | 0.0805 | 0.0813 | 0.0620 | 0.1102 | 0.0836 | 0.6260 | 0.7042 | 0.0013 | 0.0023 | 0.0047 | 0.0085 | 0.0214 | 0.0194 | 0.0343 | 0.0461 | 0.0909 | 0.1071 | 0.1496 | 0.1720 | 0.1127 | 0.1236 | 0.1444 | 0.1384 | 0.4406 | 0.3827 | 0.0026 | 0.0058 | 0.0125 | 0.0295 | 0.0655 | 0.1210 | 0.1079 | 0.1339 | 0.5213 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 919 | 384 | 3864 | 10644 | 549.9 | 111.66 | 119.69 | 118.07 | 401 | 445 | 482 | 515 | 547 | 581 | 614 | 651 | 699 | 0.0750 | 798 | 1.029 | 90.48 | 35.85 | 1 | 0.0663 | 256 | 0.0007 | 70.72 | 7.491 | 0.1370 | 314839.0 | 187000000 | 115000000000 | 72500000000000 | 0.4423 | 0.2000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0000 | 0.0131 | 0.0027 | 0.0668 | 0.0158 | 0.1439 | 0.0363 | 0.1447 | 0.0328 | 0.1681 | 0.0507 | 0.4596 | 0.8617 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0051 | 0.0021 | 0.0277 | 0.0136 | 0.0621 | 0.0288 | 0.0535 | 0.0207 | 0.0701 | 0.0298 | 0.7804 | 0.9050 | 0.0029 | 0.0519 | 0.0114 | 0.0390 | 0.0157 | 0.0390 | 0.0672 | 0.1818 | 0.1502 | 0.2338 | 0.1788 | 0.1948 | 0.1288 | 0.1169 | 0.1431 | 0.0519 | 0.3019 | 0.0909 | 0.0000 | 0.0010 | 0.0037 | 0.0199 | 0.0659 | 0.1141 | 0.0795 | 0.1141 | 0.6018 | 11 | 15 | 23 | 44 | 81 | 122 | 165 | 219 | 293 | 0.0192 | 16.46 | 5.675 | 0.4317 | 28266.0 | 8580000 | 3000000000 | 1160000000000 | 0.4622 | 0.1810 | 0.0320 | 0.0021 | 0.1652 | 0.0111 | 0.2654 | 0.0848 | 0.1446 | 0.1330 | 0.1611 | 0.2072 | 0.1002 | 0.1734 | 0.0666 | 0.1199 | 0.0411 | 0.1273 | 0.0238 | 0.1413 | 0.0004 | 0.0004 | 0.0002 | 0.0004 | 0.0026 | 0.0020 | 0.0100 | 0.0065 | 0.0573 | 0.0464 | 0.0915 | 0.0770 | 0.0713 | 0.0525 | 0.1045 | 0.0919 | 0.6622 | 0.7230 | 0.0003 | 0.0006 | 0.0019 | 0.0016 | 0.0054 | 0.0048 | 0.0200 | 0.0279 | 0.0764 | 0.0901 | 0.1300 | 0.1487 | 0.0978 | 0.0983 | 0.1230 | 0.1376 | 0.5451 | 0.4903 | 0.0005 | 0.0016 | 0.0023 | 0.0137 | 0.0615 | 0.1121 | 0.0896 | 0.1246 | 0.5942 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 | |
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 608 | 285 | 12711 | 40214 | 295.5 | 67.78 | 143.73 | 163.15 | 209 | 239 | 260 | 277 | 293 | 309 | 328 | 350 | 384 | 0.0353 | 1418 | 1.016 | 119.62 | 46.69 | 2 | 0.0271 | 344 | 0.0013 | 26.32 | 6.921 | 0.2277 | 91894.8 | 30000000 | 10200000000 | 3620000000000 | 0.4370 | 0.2187 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0006 | 0.0194 | 0.0020 | 0.0643 | 0.0160 | 0.1388 | 0.0422 | 0.1306 | 0.0429 | 0.1606 | 0.0610 | 0.4809 | 0.8354 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0053 | 0.0011 | 0.0274 | 0.0105 | 0.0590 | 0.0245 | 0.0510 | 0.0194 | 0.0701 | 0.0291 | 0.7861 | 0.9154 | 0.0071 | 0.0128 | 0.0075 | 0.0192 | 0.0179 | 0.0417 | 0.0613 | 0.1330 | 0.1289 | 0.1875 | 0.1811 | 0.2051 | 0.1097 | 0.0865 | 0.1506 | 0.1330 | 0.3358 | 0.1811 | 0.0008 | 0.0024 | 0.0064 | 0.0265 | 0.0750 | 0.1260 | 0.1010 | 0.1299 | 0.5321 | 11 | 17 | 28 | 49 | 80 | 122 | 178 | 254 | 371 | 0.0435 | 17.85 | 5.232 | 0.4864 | 47276.4 | 22300000 | 13100000000 | 8910000000000 | 0.4347 | 0.1843 | 0.0559 | 0.0013 | 0.1725 | 0.0173 | 0.2681 | 0.1183 | 0.1475 | 0.1465 | 0.1431 | 0.1771 | 0.0944 | 0.1809 | 0.0533 | 0.1241 | 0.0376 | 0.1058 | 0.0276 | 0.1288 | 0.0001 | 0.0001 | 0.0004 | 0.0006 | 0.0019 | 0.0015 | 0.0116 | 0.0097 | 0.0649 | 0.0509 | 0.1109 | 0.0898 | 0.0752 | 0.0672 | 0.1098 | 0.0956 | 0.6253 | 0.6846 | 0.0006 | 0.0007 | 0.0011 | 0.0013 | 0.0036 | 0.0075 | 0.0213 | 0.0276 | 0.0840 | 0.0988 | 0.1417 | 0.1531 | 0.0910 | 0.0952 | 0.1254 | 0.1330 | 0.5313 | 0.4828 | 0.0003 | 0.0013 | 0.0032 | 0.0164 | 0.0787 | 0.1225 | 0.0861 | 0.1208 | 0.5707 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 948 | 602 | 5482 | 6626 | 431.8 | 96.54 | 133.95 | 147.02 | 321 | 351 | 372 | 394 | 415 | 441 | 472 | 515 | 567 | 0.1180 | 782 | 1.222 | 113.85 | 42.45 | 1 | 0.0520 | 285 | 0.0009 | 43.04 | 7.265 | 0.1744 | 195782.0 | 93200000 | 46500000000 | 24300000000000 | 0.4072 | 0.2460 | 0.0012 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0145 | 0.0012 | 0.0707 | 0.0208 | 0.1385 | 0.0387 | 0.1405 | 0.0363 | 0.1657 | 0.0562 | 0.4649 | 0.8469 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0056 | 0.0004 | 0.0357 | 0.0158 | 0.0655 | 0.0214 | 0.0748 | 0.0204 | 0.0919 | 0.0339 | 0.7240 | 0.9081 | 0.0029 | 0.0035 | 0.0029 | 0.0035 | 0.0095 | 0.0141 | 0.0475 | 0.0742 | 0.0846 | 0.1696 | 0.1454 | 0.2155 | 0.1055 | 0.1060 | 0.1084 | 0.1095 | 0.4933 | 0.3039 | 0.0021 | 0.0008 | 0.0119 | 0.0296 | 0.0716 | 0.1067 | 0.0809 | 0.0949 | 0.6014 | 11 | 15 | 23 | 44 | 79 | 120 | 169 | 238 | 356 | 0.0197 | 24.70 | 5.729 | 0.4245 | 39552.5 | 16000000 | 7850000000 | 4460000000000 | 0.4462 | 0.1848 | 0.0329 | 0.0007 | 0.1368 | 0.0059 | 0.2053 | 0.0553 | 0.2026 | 0.1211 | 0.1539 | 0.1895 | 0.1250 | 0.1914 | 0.0645 | 0.1303 | 0.0500 | 0.1375 | 0.0289 | 0.1684 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0012 | 0.0119 | 0.0055 | 0.0633 | 0.0525 | 0.0857 | 0.0756 | 0.0689 | 0.0619 | 0.1147 | 0.1026 | 0.6548 | 0.7008 | 0.0010 | 0.0017 | 0.0010 | 0.0017 | 0.0048 | 0.0039 | 0.0162 | 0.0231 | 0.0796 | 0.0732 | 0.0977 | 0.1082 | 0.0881 | 0.0890 | 0.1148 | 0.1104 | 0.5970 | 0.5887 | 0.0004 | 0.0000 | 0.0029 | 0.0139 | 0.0644 | 0.1076 | 0.0770 | 0.1129 | 0.6209 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 689 | 7600 | 15811 | 210.9 | 43.78 | 142.17 | 171.25 | 159 | 173 | 185 | 196 | 207 | 218 | 230 | 245 | 269 | 0.0623 | 985 | 1.140 | 88.32 | 39.01 | 1 | 0.0330 | 251 | 0.0011 | 39.63 | 7.083 | 0.1887 | 46382.0 | 10600000 | 2540000000 | 632000000000 | 0.4649 | 0.1876 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0031 | 0.0000 | 0.0156 | 0.0013 | 0.0581 | 0.0167 | 0.1363 | 0.0365 | 0.1516 | 0.0327 | 0.1761 | 0.0584 | 0.4584 | 0.8545 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0074 | 0.0004 | 0.0307 | 0.0110 | 0.0643 | 0.0228 | 0.0646 | 0.0137 | 0.0939 | 0.0247 | 0.7375 | 0.9274 | 0.0050 | 0.0238 | 0.0058 | 0.0149 | 0.0284 | 0.0387 | 0.0984 | 0.1310 | 0.1418 | 0.1786 | 0.1818 | 0.1994 | 0.0992 | 0.1012 | 0.1276 | 0.1250 | 0.3119 | 0.1875 | 0.0009 | 0.0020 | 0.0111 | 0.0386 | 0.0873 | 0.1384 | 0.1199 | 0.1335 | 0.4684 | 11 | 13 | 15 | 21 | 53 | 120 | 192 | 279 | 392 | 0.0646 | 26.36 | 5.217 | 0.4922 | 49534.8 | 23000000 | 12600000000 | 7870000000000 | 0.5544 | 0.1062 | 0.0575 | 0.0021 | 0.2553 | 0.0185 | 0.3274 | 0.1627 | 0.1596 | 0.1906 | 0.0883 | 0.1964 | 0.0624 | 0.1886 | 0.0300 | 0.1011 | 0.0130 | 0.0719 | 0.0065 | 0.0682 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0005 | 0.0010 | 0.0079 | 0.0052 | 0.0517 | 0.0451 | 0.0963 | 0.0833 | 0.0703 | 0.0593 | 0.0991 | 0.0835 | 0.6739 | 0.7223 | 0.0002 | 0.0004 | 0.0013 | 0.0015 | 0.0029 | 0.0043 | 0.0140 | 0.0201 | 0.0689 | 0.0788 | 0.1235 | 0.1391 | 0.0936 | 0.0936 | 0.1214 | 0.1176 | 0.5743 | 0.5445 | 0.0000 | 0.0003 | 0.0017 | 0.0095 | 0.0610 | 0.1104 | 0.0758 | 0.1149 | 0.6263 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 127 | 580 | 4890 | 10021 | 167.2 | 45.62 | 128.15 | 116.75 | 114 | 127 | 138 | 149 | 161 | 173 | 187 | 205 | 230 | 0.0875 | 877 | 0.739 | 103.47 | 30.61 | 1 | 0.0599 | 293 | 0.0011 | 49.25 | 7.043 | 0.1864 | 30027.2 | 5780000 | 1190000000 | 261000000000 | 0.4177 | 0.2308 | 0.0016 | 0.0002 | 0.0054 | 0.0005 | 0.0140 | 0.0014 | 0.0490 | 0.0063 | 0.1319 | 0.0305 | 0.2074 | 0.0675 | 0.1903 | 0.0781 | 0.1763 | 0.1142 | 0.2241 | 0.7013 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0025 | 0.0004 | 0.0156 | 0.0008 | 0.0542 | 0.0191 | 0.0826 | 0.0342 | 0.0846 | 0.0354 | 0.1043 | 0.0562 | 0.6544 | 0.8538 | 0.0018 | 0.0045 | 0.0120 | 0.0112 | 0.0221 | 0.0604 | 0.0766 | 0.1029 | 0.1485 | 0.2215 | 0.1845 | 0.1879 | 0.1236 | 0.1342 | 0.1494 | 0.1409 | 0.2814 | 0.1365 | 0.0005 | 0.0023 | 0.0104 | 0.0379 | 0.0974 | 0.1312 | 0.1028 | 0.1398 | 0.4779 | 18 | 32 | 51 | 70 | 93 | 120 | 156 | 205 | 286 | 0.0036 | 60.89 | 6.753 | 0.2645 | 30050.3 | 9900000 | 4030000000 | 1890000000000 | 0.5421 | 0.1392 | 0.0340 | 0.0028 | 0.1454 | 0.0145 | 0.2293 | 0.0767 | 0.1787 | 0.1127 | 0.1537 | 0.1622 | 0.1192 | 0.1926 | 0.0769 | 0.1335 | 0.0429 | 0.1338 | 0.0199 | 0.1711 | 0.0004 | 0.0007 | 0.0017 | 0.0025 | 0.0043 | 0.0030 | 0.0229 | 0.0167 | 0.0712 | 0.0549 | 0.1280 | 0.1023 | 0.1062 | 0.0776 | 0.1235 | 0.1156 | 0.5418 | 0.6267 | 0.0023 | 0.0008 | 0.0052 | 0.0076 | 0.0124 | 0.0139 | 0.0322 | 0.0458 | 0.0970 | 0.1178 | 0.1758 | 0.1715 | 0.1120 | 0.1126 | 0.1143 | 0.1182 | 0.4489 | 0.4119 | 0.0005 | 0.0034 | 0.0093 | 0.0276 | 0.0928 | 0.1477 | 0.1082 | 0.1318 | 0.4785 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 | |
MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1202 | 629 | 3328 | 8418 | 107.3 | 34.23 | 123.15 | 94.86 | 68 | 80 | 88 | 96 | 104 | 112 | 122 | 135 | 151 | 0.0986 | 830 | 0.231 | 169.10 | 42.20 | 3 | 0.2897 | 964 | 0.0010 | 62.39 | 7.144 | 0.1516 | 12681.7 | 1630000 | 227000000 | 34000000000 | 0.4848 | 0.1833 | 0.0006 | 0.0000 | 0.0062 | 0.0004 | 0.0296 | 0.0037 | 0.0889 | 0.0116 | 0.1705 | 0.0511 | 0.2341 | 0.1335 | 0.1692 | 0.1051 | 0.1316 | 0.1491 | 0.1692 | 0.5455 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0016 | 0.0003 | 0.0213 | 0.0046 | 0.0585 | 0.0354 | 0.1101 | 0.0827 | 0.0876 | 0.0423 | 0.1146 | 0.0813 | 0.6052 | 0.7534 | 0.0036 | 0.0109 | 0.0024 | 0.0163 | 0.0182 | 0.0245 | 0.0812 | 0.1226 | 0.1818 | 0.2670 | 0.1782 | 0.1853 | 0.1224 | 0.0981 | 0.1479 | 0.1390 | 0.2642 | 0.1362 | 0.0006 | 0.0006 | 0.0077 | 0.0379 | 0.1247 | 0.1433 | 0.1093 | 0.1549 | 0.4210 | 27 | 47 | 62 | 77 | 96 | 120 | 152 | 193 | 257 | 0.0090 | 14.86 | 5.556 | 0.4071 | 24163.0 | 6350000 | 2030000000 | 746000000000 | 0.5797 | 0.1151 | 0.0304 | 0.0016 | 0.1306 | 0.0066 | 0.2172 | 0.0487 | 0.1928 | 0.1050 | 0.1637 | 0.1644 | 0.1333 | 0.2011 | 0.0683 | 0.1502 | 0.0501 | 0.1416 | 0.0135 | 0.1808 | 0.0005 | 0.0008 | 0.0036 | 0.0010 | 0.0061 | 0.0053 | 0.0229 | 0.0187 | 0.0800 | 0.0542 | 0.1217 | 0.0941 | 0.1144 | 0.0875 | 0.1389 | 0.1205 | 0.5119 | 0.6179 | 0.0011 | 0.0034 | 0.0053 | 0.0116 | 0.0167 | 0.0198 | 0.0456 | 0.0545 | 0.1094 | 0.1369 | 0.1759 | 0.1803 | 0.1265 | 0.1345 | 0.1527 | 0.1572 | 0.3666 | 0.3018 | 0.0012 | 0.0055 | 0.0092 | 0.0348 | 0.0944 | 0.1521 | 0.1225 | 0.1512 | 0.4291 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 308 | 627 | 7227 | 23465 | 215.5 | 41.93 | 145.25 | 174.73 | 162 | 178 | 191 | 202 | 212 | 224 | 237 | 252 | 273 | 0.0445 | 1045 | 1.162 | 108.98 | 41.15 | 1 | 0.0381 | 275 | 0.0011 | 40.67 | 7.077 | 0.1835 | 48189.1 | 11200000 | 2670000000 | 661000000000 | 0.4653 | 0.1920 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0045 | 0.0000 | 0.0153 | 0.0013 | 0.0650 | 0.0143 | 0.1342 | 0.0316 | 0.1506 | 0.0321 | 0.1783 | 0.0507 | 0.4501 | 0.8700 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0054 | 0.0001 | 0.0288 | 0.0103 | 0.0653 | 0.0222 | 0.0624 | 0.0119 | 0.0865 | 0.0207 | 0.7501 | 0.9347 | 0.0050 | 0.0140 | 0.0231 | 0.0698 | 0.0330 | 0.1302 | 0.0759 | 0.1628 | 0.1485 | 0.1907 | 0.1774 | 0.1628 | 0.1238 | 0.0977 | 0.1493 | 0.1163 | 0.2640 | 0.0558 | 0.0014 | 0.0020 | 0.0084 | 0.0341 | 0.0981 | 0.1388 | 0.1119 | 0.1380 | 0.4672 | 12 | 14 | 17 | 26 | 56 | 119 | 196 | 282 | 392 | 0.0424 | 27.68 | 5.411 | 0.4772 | 51628.4 | 24900000 | 14400000000 | 9560000000000 | 0.4794 | 0.1582 | 0.0785 | 0.0020 | 0.2700 | 0.0215 | 0.3485 | 0.1855 | 0.1364 | 0.2031 | 0.0927 | 0.2112 | 0.0438 | 0.1640 | 0.0210 | 0.1007 | 0.0057 | 0.0672 | 0.0034 | 0.0448 | 0.0001 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0004 | 0.0088 | 0.0057 | 0.0525 | 0.0474 | 0.0960 | 0.0821 | 0.0705 | 0.0572 | 0.1013 | 0.0869 | 0.6700 | 0.7200 | 0.0001 | 0.0009 | 0.0013 | 0.0022 | 0.0034 | 0.0060 | 0.0176 | 0.0207 | 0.0700 | 0.0762 | 0.1210 | 0.1334 | 0.0883 | 0.0944 | 0.1155 | 0.1235 | 0.5829 | 0.5428 | 0.0000 | 0.0003 | 0.0021 | 0.0129 | 0.0602 | 0.1081 | 0.0860 | 0.1052 | 0.6252 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 212 | 744 | 6614 | 10325 | 163.1 | 32.35 | 119.28 | 84.78 | 125 | 138 | 147 | 155 | 161 | 167 | 175 | 185 | 203 | 0.0792 | 818 | 1.172 | 127.35 | 40.25 | 1 | 0.0452 | 299 | 0.0020 | 27.70 | 6.559 | 0.2300 | 27650.6 | 4880000 | 902000000 | 175000000000 | 0.4500 | 0.2031 | 0.0002 | 0.0000 | 0.0008 | 0.0003 | 0.0033 | 0.0005 | 0.0157 | 0.0009 | 0.0518 | 0.0158 | 0.1045 | 0.0311 | 0.1239 | 0.0356 | 0.1680 | 0.0538 | 0.5318 | 0.8621 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0073 | 0.0005 | 0.0238 | 0.0110 | 0.0514 | 0.0224 | 0.0550 | 0.0146 | 0.0835 | 0.0286 | 0.7771 | 0.9229 | 0.0114 | 0.0090 | 0.0194 | 0.0495 | 0.0411 | 0.0495 | 0.1006 | 0.1802 | 0.1600 | 0.2117 | 0.1794 | 0.1757 | 0.1486 | 0.0991 | 0.1394 | 0.0991 | 0.2000 | 0.1261 | 0.0006 | 0.0063 | 0.0157 | 0.0466 | 0.0913 | 0.1326 | 0.1222 | 0.1698 | 0.4148 | 30 | 47 | 62 | 79 | 97 | 119 | 148 | 185 | 240 | 0.0026 | 32.10 | 6.579 | 0.2832 | 21415.5 | 4970000 | 1370000000 | 425000000000 | 0.5726 | 0.1051 | 0.0233 | 0.0012 | 0.1341 | 0.0059 | 0.2743 | 0.0446 | 0.1832 | 0.1006 | 0.1522 | 0.1877 | 0.1071 | 0.1954 | 0.0694 | 0.1475 | 0.0367 | 0.1460 | 0.0197 | 0.1709 | 0.0004 | 0.0005 | 0.0023 | 0.0009 | 0.0082 | 0.0027 | 0.0218 | 0.0148 | 0.0827 | 0.0624 | 0.1269 | 0.0968 | 0.1019 | 0.0859 | 0.1392 | 0.1237 | 0.5166 | 0.6124 | 0.0015 | 0.0023 | 0.0073 | 0.0051 | 0.0094 | 0.0167 | 0.0462 | 0.0607 | 0.1152 | 0.1293 | 0.1711 | 0.1795 | 0.1100 | 0.1215 | 0.1510 | 0.1484 | 0.3883 | 0.3364 | 0.0007 | 0.0041 | 0.0070 | 0.0374 | 0.0934 | 0.1539 | 0.1074 | 0.1421 | 0.4540 | |||
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 400 | 407 | 6276 | 11399 | 375.7 | 86.02 | 140.41 | 164.45 | 245 | 323 | 357 | 378 | 396 | 413 | 428 | 444 | 463 | 0.0798 | 910 | 1.138 | 23.43 | 8.49 | 5 | 0.0099 | 62 | 0.0020 | 19.90 | 6.638 | 0.2782 | 148520.0 | 60600000 | 25300000000 | 10700000000000 | 0.3938 | 0.2401 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0021 | 0.0000 | 0.0137 | 0.0000 | 0.0354 | 0.0108 | 0.0722 | 0.0252 | 0.0748 | 0.0104 | 0.1107 | 0.0183 | 0.6891 | 0.9352 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0137 | 0.0108 | 0.0298 | 0.0252 | 0.0216 | 0.0104 | 0.0319 | 0.0169 | 0.9017 | 0.9367 | 0.0072 | 1.0000 | 0.0184 | 0.0000 | 0.0419 | 0.0000 | 0.0593 | 0.0000 | 0.0992 | 0.0000 | 0.1329 | 0.0000 | 0.1299 | 0.0000 | 0.1227 | 0.0000 | 0.3885 | 0.0000 | 0.0000 | 0.0010 | 0.0031 | 0.0067 | 0.0347 | 0.0601 | 0.0515 | 0.0772 | 0.7656 | 9 | 11 | 15 | 29 | 67 | 119 | 185 | 272 | 389 | 0.0593 | 7.25 | 4.451 | 0.5348 | 46754.1 | 20300000 | 10200000000 | 5650000000000 | 0.4511 | 0.1880 | 0.0237 | 0.0010 | 0.1225 | 0.0110 | 0.2381 | 0.0628 | 0.1729 | 0.1187 | 0.1275 | 0.1830 | 0.1265 | 0.1945 | 0.0810 | 0.1237 | 0.0632 | 0.1062 | 0.0445 | 0.1990 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0017 | 0.0009 | 0.0089 | 0.0072 | 0.0450 | 0.0402 | 0.0820 | 0.0693 | 0.0542 | 0.0504 | 0.0858 | 0.0775 | 0.7214 | 0.7543 | 0.0003 | 0.0003 | 0.0030 | 0.0015 | 0.0041 | 0.0034 | 0.0160 | 0.0153 | 0.0574 | 0.0644 | 0.0907 | 0.1103 | 0.0655 | 0.0754 | 0.1045 | 0.1051 | 0.6586 | 0.6243 | 0.0002 | 0.0002 | 0.0019 | 0.0112 | 0.0594 | 0.0827 | 0.0622 | 0.0946 | 0.6875 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 751 | 267 | 3996 | 13985 | 152.2 | 33.85 | 141.01 | 145.07 | 113 | 124 | 133 | 140 | 148 | 155 | 165 | 178 | 196 | 0.0633 | 885 | 1.001 | 83.55 | 24.08 | 2 | 0.0488 | 195 | 0.0021 | 21.13 | 6.445 | 0.2487 | 24325.1 | 4090000 | 723000000 | 135000000000 | 0.4071 | 0.2421 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0046 | 0.0000 | 0.0217 | 0.0008 | 0.0685 | 0.0210 | 0.1371 | 0.0445 | 0.1470 | 0.0450 | 0.1702 | 0.0623 | 0.4497 | 0.8264 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0072 | 0.0003 | 0.0302 | 0.0141 | 0.0688 | 0.0303 | 0.0676 | 0.0197 | 0.0894 | 0.0351 | 0.7352 | 0.9005 | 0.0015 | 0.0049 | 0.0160 | 0.0099 | 0.0248 | 0.0049 | 0.0758 | 0.1626 | 0.1487 | 0.1576 | 0.1662 | 0.1921 | 0.1122 | 0.1379 | 0.1327 | 0.1281 | 0.3222 | 0.2020 | 0.0033 | 0.0044 | 0.0116 | 0.0311 | 0.0843 | 0.1337 | 0.0943 | 0.1281 | 0.5092 | 19 | 33 | 50 | 68 | 90 | 118 | 157 | 223 | 339 | 0.0069 | 33.28 | 6.213 | 0.3970 | 40926.9 | 17700000 | 9520000000 | 5890000000000 | 0.6594 | 0.0769 | 0.0120 | 0.0022 | 0.0718 | 0.0095 | 0.1486 | 0.0217 | 0.1626 | 0.0638 | 0.1950 | 0.1371 | 0.1406 | 0.1875 | 0.1077 | 0.1501 | 0.0803 | 0.1521 | 0.0813 | 0.2760 | 0.0019 | 0.0005 | 0.0029 | 0.0029 | 0.0075 | 0.0052 | 0.0196 | 0.0142 | 0.0618 | 0.0479 | 0.0945 | 0.0817 | 0.0723 | 0.0641 | 0.1133 | 0.0906 | 0.6263 | 0.6929 | 0.0008 | 0.0003 | 0.0044 | 0.0049 | 0.0072 | 0.0097 | 0.0294 | 0.0346 | 0.0744 | 0.0822 | 0.1224 | 0.1275 | 0.0945 | 0.1005 | 0.1237 | 0.1287 | 0.5430 | 0.5117 | 0.0017 | 0.0042 | 0.0089 | 0.0256 | 0.0701 | 0.1033 | 0.0830 | 0.1114 | 0.5917 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 658 | 779 | 5169 | 11172 | 137.7 | 32.46 | 113.17 | 91.87 | 100 | 111 | 120 | 127 | 134 | 142 | 150 | 160 | 178 | 0.0719 | 803 | 0.859 | 104.81 | 28.16 | 1 | 0.0530 | 274 | 0.0021 | 21.91 | 6.455 | 0.2447 | 20003.2 | 3080000 | 502000000 | 87100000000 | 0.4380 | 0.2131 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0072 | 0.0000 | 0.0208 | 0.0021 | 0.0760 | 0.0199 | 0.1417 | 0.0475 | 0.1466 | 0.0488 | 0.1981 | 0.0785 | 0.4089 | 0.8031 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0077 | 0.0008 | 0.0363 | 0.0134 | 0.0672 | 0.0294 | 0.0593 | 0.0203 | 0.0997 | 0.0401 | 0.7272 | 0.8959 | 0.0081 | 0.0139 | 0.0185 | 0.0209 | 0.0288 | 0.0453 | 0.0819 | 0.1603 | 0.1453 | 0.1672 | 0.1926 | 0.1812 | 0.1119 | 0.0836 | 0.1407 | 0.1324 | 0.2722 | 0.1951 | 0.0025 | 0.0042 | 0.0148 | 0.0420 | 0.0954 | 0.1238 | 0.1081 | 0.1361 | 0.4731 | 15 | 30 | 49 | 70 | 92 | 118 | 149 | 185 | 238 | 0.0049 | 34.56 | 6.477 | 0.3146 | 21247.0 | 5290000 | 1630000000 | 593000000000 | 0.5230 | 0.1320 | 0.0237 | 0.0013 | 0.1084 | 0.0065 | 0.2323 | 0.0500 | 0.1730 | 0.0940 | 0.1806 | 0.1655 | 0.1412 | 0.2079 | 0.0846 | 0.1542 | 0.0415 | 0.1364 | 0.0146 | 0.1841 | 0.0004 | 0.0003 | 0.0009 | 0.0000 | 0.0057 | 0.0022 | 0.0210 | 0.0114 | 0.0670 | 0.0515 | 0.1169 | 0.0950 | 0.0867 | 0.0772 | 0.1217 | 0.1026 | 0.5799 | 0.6597 | 0.0011 | 0.0007 | 0.0029 | 0.0076 | 0.0111 | 0.0152 | 0.0315 | 0.0444 | 0.0978 | 0.1136 | 0.1574 | 0.1758 | 0.0999 | 0.1242 | 0.1479 | 0.1351 | 0.4505 | 0.3834 | 0.0009 | 0.0021 | 0.0064 | 0.0277 | 0.0813 | 0.1285 | 0.1054 | 0.1321 | 0.5156 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1039 | 222 | 8267 | 22106 | 288.0 | 59.05 | 151.11 | 185.59 | 216 | 238 | 254 | 269 | 282 | 298 | 314 | 336 | 366 | 0.0470 | 1038 | 1.207 | 123.17 | 44.29 | 1 | 0.0368 | 304 | 0.0006 | 72.43 | 7.591 | 0.1414 | 86440.9 | 27000000 | 8770000000 | 2960000000000 | 0.4619 | 0.1920 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0001 | 0.0163 | 0.0014 | 0.0611 | 0.0158 | 0.1248 | 0.0327 | 0.1394 | 0.0332 | 0.1689 | 0.0503 | 0.4834 | 0.8666 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0049 | 0.0000 | 0.0290 | 0.0113 | 0.0560 | 0.0195 | 0.0638 | 0.0161 | 0.0864 | 0.0281 | 0.7592 | 0.9250 | 0.0044 | 0.0122 | 0.0059 | 0.0122 | 0.0344 | 0.0459 | 0.0659 | 0.0979 | 0.1553 | 0.2049 | 0.1919 | 0.2141 | 0.1114 | 0.1070 | 0.1495 | 0.1346 | 0.2813 | 0.1713 | 0.0026 | 0.0018 | 0.0099 | 0.0342 | 0.0861 | 0.1315 | 0.1084 | 0.1380 | 0.4874 | 12 | 15 | 17 | 24 | 55 | 118 | 196 | 294 | 424 | 0.0394 | 36.87 | 5.514 | 0.4378 | 57275.2 | 29300000 | 17900000000 | 12400000000000 | 0.4786 | 0.1762 | 0.0641 | 0.0023 | 0.1929 | 0.0255 | 0.2734 | 0.1224 | 0.1781 | 0.1756 | 0.1168 | 0.1948 | 0.0851 | 0.1693 | 0.0556 | 0.1219 | 0.0221 | 0.0910 | 0.0119 | 0.0973 | 0.0001 | 0.0000 | 0.0005 | 0.0005 | 0.0019 | 0.0008 | 0.0100 | 0.0091 | 0.0516 | 0.0439 | 0.0899 | 0.0793 | 0.0692 | 0.0605 | 0.0927 | 0.0806 | 0.6841 | 0.7253 | 0.0014 | 0.0005 | 0.0020 | 0.0011 | 0.0047 | 0.0047 | 0.0137 | 0.0179 | 0.0676 | 0.0722 | 0.1069 | 0.1192 | 0.0847 | 0.0896 | 0.1139 | 0.1168 | 0.6051 | 0.5781 | 0.0001 | 0.0011 | 0.0038 | 0.0118 | 0.0592 | 0.1021 | 0.0731 | 0.1069 | 0.6419 |