LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
MCF7 TGX221
0.37
uM
LJP5
0.9944 0.0108 0.9915 0.0149
MCF7 Torin1
0.37
uM
LJP6
0.3223 0.0078 0.0590 0.0144
MCF7 Torin2
0.37
uM
LJP5
0.2542 0.0053 -0.0361 0.0269
MCF7 Tozasertib
0.37
uM
LJP5
0.3192 0.0313 0.0564 0.0208
MCF7 Trametinib
0.37
uM
LJP5
0.4985 0.0120 0.3042 0.0005
MCF7 TWS119
0.37
uM
LJP5
1.0206 0.0362 1.0291 0.0515
MCF7 Vemurafenib
0.37
uM
LJP5
1.0623 0.0133 1.0857 0.0166
MCF7 Withaferin A
0.37
uM
LJP5
0.4590 0.0271 0.2470 0.0535
MCF7 Withaferin A
0.37
uM
LJP6
0.4297 0.0137 0.2069 0.0369
MCF7 WYE-125132
0.37
uM
LJP6
0.3481 0.0235 0.0951 0.0301
MCF7 WZ3105
0.37
uM
LJP5
0.1547 0.0360 -0.1720 0.0264
MCF7 XMD11-50
0.37
uM
LJP6
0.6540 0.0048 0.5197 0.0051
MCF7 Y39983
0.37
uM
LJP6
0.9740 0.0248 0.9651 0.0337
MCF7 YM 201636
0.37
uM
LJP5
0.8960 0.0241 0.8554 0.0347
MCF7 ZSTK474
0.37
uM
LJP6
0.3524 0.0122 0.1009 0.0183
MCF7 Afatinib
1.11
uM
LJP6
0.7583 0.0382 0.6623 0.0589
MCF7 Sigma A6730
1.11
uM
LJP5
0.5801 0.0153 0.4158 0.0340
MCF7 Alvocidib
1.11
uM
LJP6
0.1277 0.0218 -0.2104 0.0097
MCF7 AT-7519
1.11
uM
LJP6
0.1498 0.0317 -0.1792 0.0262
MCF7 AZD 5438
1.11
uM
LJP6
0.2301 0.0295 -0.0689 0.0426
MCF7 AZD-6482
1.11
uM
LJP5
0.9424 0.0154 0.9197 0.0224
MCF7 AZD7762
1.11
uM
LJP6
0.2796 0.0239 0.0008 0.0125
MCF7 AZD8055
1.11
uM
LJP6
0.2759 0.0181 -0.0055 0.0295
MCF7 AZD8330
1.11
uM
LJP5
0.5349 0.0204 0.3545 0.0262
MCF7 Barasertib
1.11
uM
LJP5
0.3462 0.0151 0.0927 0.0106