LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T TWS119
0.37
uM
LJP5
 72
hr
 658 3875 3846 1.0076 1.0092
Hs 578T Vemurafenib
0.37
uM
LJP5
 72
hr
 658 3892 3846 1.0120 1.0145
Hs 578T Withaferin A
0.37
uM
LJP5
 72
hr
 658 3400 3846 0.8840 0.8601
Hs 578T Withaferin A
0.37
uM
LJP6
 72
hr
 658 3018 3846 0.7847 0.7402
Hs 578T WYE-125132
0.37
uM
LJP6
 72
hr
 658 1208 3846 0.3143 0.1727
Hs 578T WZ3105
0.37
uM
LJP5
 72
hr
 658 485 3846 0.1261 -0.0543
Hs 578T XMD11-50
0.37
uM
LJP6
 72
hr
 658 2800 3846 0.7282 0.6721
Hs 578T Y39983
0.37
uM
LJP6
 72
hr
 658 3036 3846 0.7895 0.7461
Hs 578T YM 201636
0.37
uM
LJP5
 72
hr
 658 3791 3846 0.9857 0.9827
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 658 2225 3846 0.5785 0.4915
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 658 3341 3846 0.8687 0.8416
Hs 578T Sigma A6730
1.11
uM
LJP5
 72
hr
 658 3275 3846 0.8515 0.8209
Hs 578T Alvocidib
1.11
uM
LJP6
 72
hr
 658 424 3846 0.1102 -0.0735
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 658 442 3846 0.1149 -0.0678
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 658 562 3846 0.1462 -0.0301
Hs 578T AZD-6482
1.11
uM
LJP5
 72
hr
 658 3043 3846 0.7913 0.7482
Hs 578T AZD7762
1.11
uM
LJP6
 72
hr
 658 398 3846 0.1036 -0.0815
Hs 578T AZD8055
1.11
uM
LJP6
 72
hr
 658 910 3846 0.2368 0.0792
Hs 578T AZD8330
1.11
uM
LJP5
 72
hr
 658 1003 3846 0.2608 0.1082
Hs 578T Barasertib
1.11
uM
LJP5
 72
hr
 658 1217 3846 0.3165 0.1754
Hs 578T BI-2536
1.11
uM
LJP6
 72
hr
 658 578 3846 0.1504 -0.0250
Hs 578T BMS345541
1.11
uM
LJP6
 72
hr
 658 3168 3846 0.8239 0.7875
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 658 548 3846 0.1425 -0.0346
Hs 578T GDC-0980
1.11
uM
LJP5
 72
hr
 658 1212 3846 0.3152 0.1738
Hs 578T NVP-AEW541
1.11
uM
LJP5
 72
hr
 658 3748 3846 0.9747 0.9694