LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T WZ3105
0.04
uM
LJP5
 72
hr
 658 454 3846 0.1180 -0.0641
Hs 578T XMD11-50
0.04
uM
LJP6
 72
hr
 658 3410 3846 0.8866 0.8632
Hs 578T Y39983
0.04
uM
LJP6
 72
hr
 658 3164 3846 0.8228 0.7862
Hs 578T YM 201636
0.04
uM
LJP5
 72
hr
 658 3968 3846 1.0319 1.0384
Hs 578T ZSTK474
0.04
uM
LJP6
 72
hr
 658 2989 3846 0.7772 0.7311
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 658 3670 3846 0.9542 0.9448
Hs 578T Sigma A6730
0.12
uM
LJP5
 72
hr
 658 3661 3846 0.9520 0.9421
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 658 409 3846 0.1064 -0.0781
Hs 578T AT-7519
0.12
uM
LJP6
 72
hr
 658 897 3846 0.2334 0.0751
Hs 578T AZD 5438
0.12
uM
LJP6
 72
hr
 658 2189 3846 0.5693 0.4804
Hs 578T AZD-6482
0.12
uM
LJP5
 72
hr
 658 3513 3846 0.9136 0.8957
Hs 578T AZD7762
0.12
uM
LJP6
 72
hr
 658 968 3846 0.2518 0.0973
Hs 578T AZD8055
0.12
uM
LJP6
 72
hr
 658 1002 3846 0.2605 0.1079
Hs 578T AZD8330
0.12
uM
LJP5
 72
hr
 658 989 3846 0.2571 0.1038
Hs 578T Barasertib
0.12
uM
LJP5
 72
hr
 658 1213 3846 0.3156 0.1742
Hs 578T BI-2536
0.12
uM
LJP6
 72
hr
 658 493 3846 0.1282 -0.0518
Hs 578T BMS345541
0.12
uM
LJP6
 72
hr
 658 3764 3846 0.9787 0.9744
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 658 542 3846 0.1411 -0.0362
Hs 578T GDC-0980
0.12
uM
LJP5
 72
hr
 658 1738 3846 0.4519 0.3387
Hs 578T NVP-AEW541
0.12
uM
LJP5
 72
hr
 658 3994 3846 1.0385 1.0465
Hs 578T SB590885
0.12
uM
LJP5
 72
hr
 658 4216 3846 1.0963 1.1162
Hs 578T PIK-93
0.12
uM
LJP5
 72
hr
 658 3884 3846 1.0100 1.0121
Hs 578T KIN001-043
0.12
uM
LJP6
 72
hr
 658 3858 3846 1.0032 1.0038
Hs 578T Alpelisib
0.12
uM
LJP5
 72
hr
 658 3517 3846 0.9144 0.8968
Hs 578T Luminespib
0.12
uM
LJP5
 72
hr
 658 781 3846 0.2032 0.0386