LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 TWS119
1.11
uM
LJP5
 72
hr
 1097 3079 3769 0.8170 0.7418
BT-20 Vemurafenib
1.11
uM
LJP5
 72
hr
 1097 3454 3769 0.9164 0.8821
BT-20 Withaferin A
1.11
uM
LJP5
 72
hr
 1097 990 3769 0.2626 -0.0401
BT-20 Withaferin A
1.11
uM
LJP6
 72
hr
 1097 900 3769 0.2388 -0.0738
BT-20 WYE-125132
1.11
uM
LJP6
 72
hr
 1097 1252 3769 0.3323 0.0582
BT-20 WZ3105
1.11
uM
LJP5
 72
hr
 1097 727 3769 0.1929 -0.1386
BT-20 XMD11-50
1.11
uM
LJP6
 72
hr
 1097 2396 3769 0.6357 0.4861
BT-20 Y39983
1.11
uM
LJP6
 72
hr
 1097 3260 3769 0.8650 0.8096
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1097 2848 3769 0.7555 0.6552
BT-20 ZSTK474
1.11
uM
LJP6
 72
hr
 1097 1204 3769 0.3194 0.0399
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1097 3253 3769 0.8631 0.8068
BT-20 Sigma A6730
3.33
uM
LJP5
 72
hr
 1097 3334 3769 0.8845 0.8370
BT-20 Alvocidib
3.33
uM
LJP6
 72
hr
 1097 635 3769 0.1685 -0.1729
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1097 540 3769 0.1433 -0.2085
BT-20 AZD 5438
3.33
uM
LJP6
 72
hr
 1097 761 3769 0.2021 -0.1256
BT-20 AZD-6482
3.33
uM
LJP5
 72
hr
 1097 1442 3769 0.3827 0.1293
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1097 750 3769 0.1991 -0.1298
BT-20 AZD8055
3.33
uM
LJP6
 72
hr
 1097 906 3769 0.2405 -0.0713
BT-20 AZD8330
3.33
uM
LJP5
 72
hr
 1097 3168 3769 0.8404 0.7749
BT-20 Barasertib
3.33
uM
LJP5
 72
hr
 1097 1512 3769 0.4012 0.1553
BT-20 BI-2536
3.33
uM
LJP6
 72
hr
 1097 875 3769 0.2321 -0.0832
BT-20 BMS345541
3.33
uM
LJP6
 72
hr
 1097 2738 3769 0.7264 0.6141
BT-20 SNS-032
3.33
uM
LJP6
 72
hr
 1097 740 3769 0.1963 -0.1337
BT-20 GDC-0980
3.33
uM
LJP5
 72
hr
 1097 785 3769 0.2084 -0.1166
BT-20 NVP-AEW541
3.33
uM
LJP5
 72
hr
 1097 3891 3769 1.0323 1.0456