LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 957 | 4223 | 0.2267 | -0.1574 |
| SK-BR-3 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 2775 | 4223 | 0.6571 | 0.4868 |
| SK-BR-3 | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3318 | 4223 | 0.7858 | 0.6793 |
| SK-BR-3 | YM 201636 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3632 | 4223 | 0.8600 | 0.7905 |
| SK-BR-3 | ZSTK474 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1645 | 4223 | 0.3896 | 0.0864 |
| SK-BR-3 | Afatinib | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1223 | 4223 | 0.2897 | -0.0632 |
| SK-BR-3 | Sigma A6730 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 2259 | 4223 | 0.5351 | 0.3041 |
| SK-BR-3 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1401 | 970 | 4223 | 0.2299 | -0.1527 |
| SK-BR-3 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 486 | 4223 | 0.1151 | -0.3245 |
| SK-BR-3 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 793 | 4223 | 0.1878 | -0.2157 |
| SK-BR-3 | AZD-6482 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1710 | 4223 | 0.4049 | 0.1093 |
| SK-BR-3 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 856 | 4223 | 0.2027 | -0.1933 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 443 | 4223 | 0.1050 | -0.3396 |
| SK-BR-3 | AZD8330 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 3926 | 4223 | 0.9298 | 0.8949 |
| SK-BR-3 | Barasertib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1426 | 4223 | 0.3378 | 0.0089 |
| SK-BR-3 | BI-2536 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1208 | 4223 | 0.2862 | -0.0684 |
| SK-BR-3 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 766 | 4223 | 0.1815 | -0.2250 |
| SK-BR-3 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 1068 | 4223 | 0.2530 | -0.1181 |
| SK-BR-3 | GDC-0980 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1272 | 4223 | 0.3013 | -0.0458 |
| SK-BR-3 | NVP-AEW541 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 2434 | 4223 | 0.5765 | 0.3662 |
| SK-BR-3 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 840 | 4223 | 0.1990 | -0.1989 |
| SK-BR-3 | PIK-93 | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1491 | 4223 | 0.3531 | 0.0318 |
| SK-BR-3 | KIN001-043 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 2362 | 4223 | 0.5595 | 0.3406 |
| SK-BR-3 | Alpelisib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1593 | 4223 | 0.3774 | 0.0681 |
| SK-BR-3 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1401 | 1571 | 4223 | 0.3720 | 0.0601 |