LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1097 | 2843 | 3769 | 0.7544 | 0.6535 |
BT-20 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1097 | 2663 | 3769 | 0.7066 | 0.5862 |
BT-20 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3576 | 3769 | 0.9487 | 0.9276 |
BT-20 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3777 | 3769 | 1.0021 | 1.0029 |
BT-20 | BX-912 | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3479 | 3769 | 0.9229 | 0.8913 |
BT-20 | Canertinib | 0.04 | uM | LJP6 | 72 | hr | 1097 | 3493 | 3769 | 0.9268 | 0.8968 |
BT-20 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1097 | 3972 | 3769 | 1.0539 | 1.0760 |
BT-20 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3053 | 3769 | 0.8101 | 0.7321 |
BT-20 | CGP60474 | 0.04 | uM | LJP6 | 72 | hr | 1097 | 724 | 3769 | 0.1921 | -0.1397 |
BT-20 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 1097 | 3192 | 3769 | 0.8469 | 0.7840 |
BT-20 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3635 | 3769 | 0.9644 | 0.9498 |
BT-20 | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1097 | 4112 | 3769 | 1.0910 | 1.1284 |
BT-20 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3340 | 3769 | 0.8861 | 0.8393 |
BT-20 | Momelotinib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3659 | 3769 | 0.9708 | 0.9588 |
BT-20 | Dasatinib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3075 | 3769 | 0.8159 | 0.7403 |
BT-20 | Dasatinib | 0.04 | uM | LJP6 | 72 | hr | 1097 | 1604 | 3769 | 0.4256 | 0.1898 |
BT-20 | Dovitinib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3447 | 3769 | 0.9145 | 0.8794 |
BT-20 | Enzastaurin | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3937 | 3769 | 1.0446 | 1.0629 |
BT-20 | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 3377 | 3769 | 0.8960 | 0.8532 |
BT-20 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1097 | 4073 | 3769 | 1.0807 | 1.1138 |
BT-20 | R406 | 0.04 | uM | LJP6 | 72 | hr | 1097 | 3449 | 3769 | 0.9151 | 0.8802 |
BT-20 | Pictilisib | 0.04 | uM | LJP6 | 72 | hr | 1097 | 2743 | 3769 | 0.7278 | 0.6160 |
BT-20 | Gefitinib | 0.04 | uM | LJP6 | 72 | hr | 1097 | 3523 | 3769 | 0.9346 | 0.9077 |
BT-20 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1097 | 1707 | 3769 | 0.4529 | 0.2283 |
BT-20 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1097 | 1280 | 3769 | 0.3396 | 0.0684 |