LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 TWS119
1.11
uM
LJP5
 72
hr
 1334 3827 3970 0.9639 0.9457
BT-20 Vemurafenib
1.11
uM
LJP5
 72
hr
 1334 3950 3970 0.9948 0.9922
BT-20 Withaferin A
1.11
uM
LJP5
 72
hr
 1334 708 3970 0.1785 -0.2375
BT-20 Withaferin A
1.11
uM
LJP6
 72
hr
 1334 1493 3970 0.3761 0.0602
BT-20 WYE-125132
1.11
uM
LJP6
 72
hr
 1334 1732 3970 0.4362 0.1507
BT-20 WZ3105
1.11
uM
LJP5
 72
hr
 1334 594 3970 0.1497 -0.2808
BT-20 XMD11-50
1.11
uM
LJP6
 72
hr
 1334 3623 3970 0.9125 0.8682
BT-20 Y39983
1.11
uM
LJP6
 72
hr
 1334 3860 3970 0.9722 0.9581
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1334 3248 3970 0.8181 0.7260
BT-20 ZSTK474
1.11
uM
LJP6
 72
hr
 1334 2264 3970 0.5703 0.3528
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1334 3377 3970 0.8506 0.7750
BT-20 Sigma A6730
3.33
uM
LJP5
 72
hr
 1334 3624 3970 0.9127 0.8685
BT-20 Alvocidib
3.33
uM
LJP6
 72
hr
 1334 364 3970 0.0918 -0.3681
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1334 350 3970 0.0883 -0.3733
BT-20 AZD 5438
3.33
uM
LJP6
 72
hr
 1334 1019 3970 0.2566 -0.1198
BT-20 AZD-6482
3.33
uM
LJP5
 72
hr
 1334 2082 3970 0.5244 0.2836
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1334 1438 3970 0.3623 0.0394
BT-20 AZD8055
3.33
uM
LJP6
 72
hr
 1334 1391 3970 0.3503 0.0214
BT-20 AZD8330
3.33
uM
LJP5
 72
hr
 1334 3341 3970 0.8415 0.7613
BT-20 Barasertib
3.33
uM
LJP5
 72
hr
 1334 1239 3970 0.3121 -0.0362
BT-20 BI-2536
3.33
uM
LJP6
 72
hr
 1334 769 3970 0.1937 -0.2146
BT-20 BMS345541
3.33
uM
LJP6
 72
hr
 1334 3479 3970 0.8763 0.8137
BT-20 SNS-032
3.33
uM
LJP6
 72
hr
 1334 394 3970 0.0992 -0.3568
BT-20 GDC-0980
3.33
uM
LJP5
 72
hr
 1334 897 3970 0.2260 -0.1659
BT-20 NVP-AEW541
3.33
uM
LJP5
 72
hr
 1334 4095 3970 1.0313 1.0472