LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 2543 3298 5578 0.5912 0.2486
SK-BR-3 Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 2543 3504 5578 0.6281 0.3165
SK-BR-3 Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 2543 3715 5578 0.6659 0.3860
SK-BR-3 Sorafenib
1.11
uM
LJP6
 1
B09
 72
hr
 2543 5656 5578 1.0139 1.0255
SK-BR-3 Sorafenib
1.11
uM
LJP6
 2
B09
 72
hr
 2543 5713 5578 1.0241 1.0443
SK-BR-3 Sorafenib
1.11
uM
LJP6
 3
B09
 72
hr
 2543 5869 5578 1.0520 1.0957
SK-BR-3 SU11274
1.11
uM
LJP5
 1
J09
 72
hr
 2543 5616 5578 1.0067 1.0123
SK-BR-3 SU11274
1.11
uM
LJP5
 2
J09
 72
hr
 2543 5626 5578 1.0085 1.0156
SK-BR-3 SU11274
1.11
uM
LJP5
 3
J09
 72
hr
 2543 6068 5578 1.0877 1.1612
SK-BR-3 Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 2543 5233 5578 0.9380 0.8861
SK-BR-3 Fedratinib
1.11
uM
LJP5
 2
L03
 72
hr
 2543 5149 5578 0.9230 0.8584
SK-BR-3 Fedratinib
1.11
uM
LJP5
 3
L03
 72
hr
 2543 5208 5578 0.9336 0.8779
SK-BR-3 TGX221
1.11
uM
LJP5
 1
H21
 72
hr
 2543 5780 5578 1.0361 1.0663
SK-BR-3 TGX221
1.11
uM
LJP5
 2
H21
 72
hr
 2543 5598 5578 1.0035 1.0064
SK-BR-3 TGX221
1.11
uM
LJP5
 3
H21
 72
hr
 2543 5848 5578 1.0483 1.0887
SK-BR-3 Torin1
1.11
uM
LJP6
 1
O15
 72
hr
 2543 1811 5578 0.3246 -0.2413
SK-BR-3 Torin1
1.11
uM
LJP6
 2
O15
 72
hr
 2543 1703 5578 0.3053 -0.2769
SK-BR-3 Torin1
1.11
uM
LJP6
 3
O15
 72
hr
 2543 1594 5578 0.2857 -0.3128
SK-BR-3 Torin2
1.11
uM
LJP5
 1
I21
 72
hr
 2543 1543 5578 0.2766 -0.3296
SK-BR-3 Torin2
1.11
uM
LJP5
 2
I21
 72
hr
 2543 1607 5578 0.2881 -0.3085
SK-BR-3 Torin2
1.11
uM
LJP5
 3
I21
 72
hr
 2543 1700 5578 0.3047 -0.2779
SK-BR-3 Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 2543 1912 5578 0.3427 -0.2080
SK-BR-3 Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 2543 2036 5578 0.3650 -0.1672
SK-BR-3 Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 2543 2094 5578 0.3754 -0.1481
SK-BR-3 Trametinib
1.11
uM
LJP5
 1
P21
 72
hr
 2543 4118 5578 0.7382 0.5188