LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 1334 2879 3970 0.7250 0.5858
BT-20 Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 1334 3138 3970 0.7903 0.6841
BT-20 Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 1334 4177 3970 1.0519 1.0782
BT-20 Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 1334 4290 3970 1.0804 1.1210
BT-20 Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 1334 3881 3970 0.9774 0.9659
BT-20 Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 1334 4161 3970 1.0479 1.0721
BT-20 Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 1334 4165 3970 1.0489 1.0736
BT-20 Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 1334 3798 3970 0.9565 0.9344
BT-20 NU7441
0.12
uM
LJP5
 1
C11
 72
hr
 1334 3908 3970 0.9842 0.9761
BT-20 NU7441
0.12
uM
LJP5
 2
C11
 72
hr
 1334 4157 3970 1.0469 1.0706
BT-20 NU7441
0.12
uM
LJP5
 3
C11
 72
hr
 1334 4235 3970 1.0665 1.1002
BT-20 Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 1334 1842 3970 0.4639 0.1924
BT-20 Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 1334 1743 3970 0.4389 0.1549
BT-20 Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 1334 1561 3970 0.3931 0.0859
BT-20 NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 1334 3193 3970 0.8041 0.7049
BT-20 NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 1334 2998 3970 0.7550 0.6310
BT-20 NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 1334 3091 3970 0.7784 0.6662
BT-20 Palbociclib
0.12
uM
LJP6
 1
E17
 72
hr
 1334 2288 3970 0.5762 0.3616
BT-20 Palbociclib
0.12
uM
LJP6
 2
E17
 72
hr
 1334 3199 3970 0.8056 0.7072
BT-20 Palbociclib
0.12
uM
LJP6
 3
E17
 72
hr
 1334 3416 3970 0.8603 0.7895
BT-20 PD0325901
0.12
uM
LJP5
 1
C05
 72
hr
 1334 3846 3970 0.9685 0.9526
BT-20 PD0325901
0.12
uM
LJP5
 2
C05
 72
hr
 1334 3858 3970 0.9716 0.9572
BT-20 PD0325901
0.12
uM
LJP5
 3
C05
 72
hr
 1334 3834 3970 0.9655 0.9481
BT-20 PD0325901
0.12
uM
LJP6
 1
E05
 72
hr
 1334 2670 3970 0.6724 0.5065
BT-20 PD0325901
0.12
uM
LJP6
 2
E05
 72
hr
 1334 4036 3970 1.0164 1.0247