LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Torin1
0.12
uM
LJP6
 3
O17
 72
hr
 1334 1652 3970 0.4160 0.1204
BT-20 Torin2
0.12
uM
LJP5
 1
I23
 72
hr
 1334 1210 3970 0.3047 -0.0473
BT-20 Torin2
0.12
uM
LJP5
 2
I23
 72
hr
 1334 1127 3970 0.2838 -0.0788
BT-20 Torin2
0.12
uM
LJP5
 3
I23
 72
hr
 1334 1218 3970 0.3067 -0.0443
BT-20 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1334 1148 3970 0.2891 -0.0708
BT-20 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 1334 1196 3970 0.3012 -0.0526
BT-20 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 1334 1316 3970 0.3314 -0.0071
BT-20 Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 1334 3410 3970 0.8588 0.7872
BT-20 Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 1334 3652 3970 0.9197 0.8790
BT-20 Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 1334 3495 3970 0.8802 0.8195
BT-20 TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 1334 4387 3970 1.1048 1.1578
BT-20 TWS119
0.12
uM
LJP5
 2
M05
 72
hr
 1334 4185 3970 1.0539 1.0812
BT-20 TWS119
0.12
uM
LJP5
 3
M05
 72
hr
 1334 4055 3970 1.0212 1.0319
BT-20 Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1334 3523 3970 0.8872 0.8301
BT-20 Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1334 3809 3970 0.9592 0.9386
BT-20 Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1334 4094 3970 1.0310 1.0467
BT-20 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1334 3214 3970 0.8094 0.7129
BT-20 Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1334 3807 3970 0.9587 0.9378
BT-20 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1334 3800 3970 0.9570 0.9352
BT-20 Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 1334 3997 3970 1.0066 1.0099
BT-20 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 1334 4260 3970 1.0728 1.1097
BT-20 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 1334 3882 3970 0.9776 0.9663
BT-20 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1334 2352 3970 0.5923 0.3859
BT-20 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1334 2128 3970 0.5359 0.3009
BT-20 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1334 2045 3970 0.5150 0.2695