LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Imatinib
10.0
uM
LJP6
2
N13
72
hr
1476 3812 3694 1.0319 1.0532
SK-BR-3 Imatinib
10.0
uM
LJP6
3
N13
72
hr
1476 3761 3694 1.0181 1.0302
SK-BR-3 JNK-9L
10.0
uM
LJP6
1
K19
72
hr
1476 1204 3694 0.3259 -0.1230
SK-BR-3 JNK-9L
10.0
uM
LJP6
2
K19
72
hr
1476 1247 3694 0.3376 -0.1036
SK-BR-3 JNK-9L
10.0
uM
LJP6
3
K19
72
hr
1476 1159 3694 0.3138 -0.1433
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
1
B19
72
hr
1476 1296 3694 0.3508 -0.0815
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
2
B19
72
hr
1476 1129 3694 0.3056 -0.1568
SK-BR-3 JW-7-24-1
10.0
uM
LJP6
3
B19
72
hr
1476 797 3694 0.2158 -0.3066
SK-BR-3 Lapatinib
10.0
uM
LJP6
1
M19
72
hr
1476 1685 3694 0.4561 0.0939
SK-BR-3 Lapatinib
10.0
uM
LJP6
2
M19
72
hr
1476 1916 3694 0.5187 0.1981
SK-BR-3 Lapatinib
10.0
uM
LJP6
3
M19
72
hr
1476 1621 3694 0.4388 0.0651
SK-BR-3 LDN-193189
10.0
uM
LJP5
1
G01
72
hr
1476 555 3694 0.1502 -0.4157
SK-BR-3 LDN-193189
10.0
uM
LJP5
2
G01
72
hr
1476 741 3694 0.2006 -0.3318
SK-BR-3 LDN-193189
10.0
uM
LJP5
3
G01
72
hr
1476 692 3694 0.1873 -0.3539
SK-BR-3 Linifanib
10.0
uM
LJP6
1
J07
72
hr
1476 1754 3694 0.4748 0.1251
SK-BR-3 Linifanib
10.0
uM
LJP6
2
J07
72
hr
1476 1934 3694 0.5235 0.2062
SK-BR-3 Linifanib
10.0
uM
LJP6
3
J07
72
hr
1476 1852 3694 0.5014 0.1693
SK-BR-3 Linsitinib
10.0
uM
LJP5
1
O19
72
hr
1476 2377 3694 0.6435 0.4060
SK-BR-3 Linsitinib
10.0
uM
LJP5
2
O19
72
hr
1476 2425 3694 0.6565 0.4277
SK-BR-3 Linsitinib
10.0
uM
LJP5
3
O19
72
hr
1476 2640 3694 0.7147 0.5246
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
1
C19
72
hr
1476 697 3694 0.1887 -0.3517
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
2
C19
72
hr
1476 555 3694 0.1502 -0.4157
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
3
C19
72
hr
1476 640 3694 0.1733 -0.3774
SK-BR-3 Mitoxantrone
10.0
uM
LJP6
1
C19
72
hr
1476 540 3694 0.1462 -0.4225
SK-BR-3 Mitoxantrone
10.0
uM
LJP6
2
C19
72
hr
1476 639 3694 0.1730 -0.3778