LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Dovitinib
10.0
uM
LJP5
3
E19
72
hr
1476 1732 3694 0.4689 0.1151
SK-BR-3 Enzastaurin
10.0
uM
LJP5
1
D13
72
hr
1476 4004 3694 1.0839 1.1398
SK-BR-3 Enzastaurin
10.0
uM
LJP5
2
D13
72
hr
1476 3728 3694 1.0092 1.0153
SK-BR-3 Enzastaurin
10.0
uM
LJP5
3
D13
72
hr
1476 1895 3694 0.5130 0.1886
SK-BR-3 Erlotinib
10.0
uM
LJP5
1
M19
72
hr
1476 1804 3694 0.4884 0.1476
SK-BR-3 Erlotinib
10.0
uM
LJP5
2
M19
72
hr
1476 1857 3694 0.5027 0.1715
SK-BR-3 Erlotinib
10.0
uM
LJP5
3
M19
72
hr
1476 1912 3694 0.5176 0.1963
SK-BR-3 Foretinib
10.0
uM
LJP5
1
H07
72
hr
1476 1333 3694 0.3609 -0.0648
SK-BR-3 Foretinib
10.0
uM
LJP5
2
H07
72
hr
1476 1442 3694 0.3904 -0.0157
SK-BR-3 Foretinib
10.0
uM
LJP5
3
H07
72
hr
1476 1373 3694 0.3717 -0.0468
SK-BR-3 R406
10.0
uM
LJP6
1
C13
72
hr
1476 2727 3694 0.7382 0.5639
SK-BR-3 R406
10.0
uM
LJP6
2
C13
72
hr
1476 2739 3694 0.7415 0.5693
SK-BR-3 R406
10.0
uM
LJP6
3
C13
72
hr
1476 2829 3694 0.7658 0.6099
SK-BR-3 Pictilisib
10.0
uM
LJP6
1
D19
72
hr
1476 1463 3694 0.3960 -0.0062
SK-BR-3 Pictilisib
10.0
uM
LJP6
2
D19
72
hr
1476 1442 3694 0.3904 -0.0157
SK-BR-3 Pictilisib
10.0
uM
LJP6
3
D19
72
hr
1476 1592 3694 0.4310 0.0520
SK-BR-3 Gefitinib
10.0
uM
LJP6
1
N07
72
hr
1476 1517 3694 0.4107 0.0182
SK-BR-3 Gefitinib
10.0
uM
LJP6
2
N07
72
hr
1476 1747 3694 0.4729 0.1219
SK-BR-3 Gefitinib
10.0
uM
LJP6
3
N07
72
hr
1476 1769 3694 0.4789 0.1318
SK-BR-3 Geldanamycin
10.0
uM
LJP5
1
O01
72
hr
1476 451 3694 0.1221 -0.4626
SK-BR-3 Geldanamycin
10.0
uM
LJP5
2
O01
72
hr
1476 630 3694 0.1705 -0.3819
SK-BR-3 Geldanamycin
10.0
uM
LJP5
3
O01
72
hr
1476 710 3694 0.1922 -0.3458
SK-BR-3 Geldanamycin
10.0
uM
LJP6
1
O01
72
hr
1476 639 3694 0.1730 -0.3778
SK-BR-3 Geldanamycin
10.0
uM
LJP6
2
O01
72
hr
1476 763 3694 0.2066 -0.3219
SK-BR-3 Geldanamycin
10.0
uM
LJP6
3
O01
72
hr
1476 664 3694 0.1798 -0.3665