LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Dasatinib
3.33
uM
LJP6
1
I02
72
hr
1476 1921 3694 0.5200 0.2004
SK-BR-3 Dasatinib
3.33
uM
LJP6
2
I02
72
hr
1476 2063 3694 0.5585 0.2644
SK-BR-3 Dasatinib
3.33
uM
LJP6
3
I02
72
hr
1476 1907 3694 0.5162 0.1941
SK-BR-3 Dovitinib
3.33
uM
LJP5
1
E20
72
hr
1476 1919 3694 0.5195 0.1995
SK-BR-3 Dovitinib
3.33
uM
LJP5
2
E20
72
hr
1476 1894 3694 0.5127 0.1882
SK-BR-3 Dovitinib
3.33
uM
LJP5
3
E20
72
hr
1476 2051 3694 0.5552 0.2590
SK-BR-3 Enzastaurin
3.33
uM
LJP5
1
D14
72
hr
1476 4060 3694 1.0991 1.1650
SK-BR-3 Enzastaurin
3.33
uM
LJP5
2
D14
72
hr
1476 4091 3694 1.1075 1.1790
SK-BR-3 Enzastaurin
3.33
uM
LJP5
3
D14
72
hr
1476 4012 3694 1.0861 1.1434
SK-BR-3 Erlotinib
3.33
uM
LJP5
1
M20
72
hr
1476 3294 3694 0.8917 0.8196
SK-BR-3 Erlotinib
3.33
uM
LJP5
2
M20
72
hr
1476 3152 3694 0.8533 0.7555
SK-BR-3 Erlotinib
3.33
uM
LJP5
3
M20
72
hr
1476 3402 3694 0.9209 0.8683
SK-BR-3 Foretinib
3.33
uM
LJP5
1
H08
72
hr
1476 1471 3694 0.3982 -0.0026
SK-BR-3 Foretinib
3.33
uM
LJP5
2
H08
72
hr
1476 1485 3694 0.4020 0.0037
SK-BR-3 Foretinib
3.33
uM
LJP5
3
H08
72
hr
1476 1408 3694 0.3812 -0.0310
SK-BR-3 R406
3.33
uM
LJP6
1
C14
72
hr
1476 3816 3694 1.0330 1.0550
SK-BR-3 R406
3.33
uM
LJP6
2
C14
72
hr
1476 4349 3694 1.1773 1.2954
SK-BR-3 R406
3.33
uM
LJP6
3
C14
72
hr
1476 4331 3694 1.1724 1.2873
SK-BR-3 Pictilisib
3.33
uM
LJP6
1
D20
72
hr
1476 1656 3694 0.4483 0.0809
SK-BR-3 Pictilisib
3.33
uM
LJP6
2
D20
72
hr
1476 1625 3694 0.4399 0.0669
SK-BR-3 Pictilisib
3.33
uM
LJP6
3
D20
72
hr
1476 1726 3694 0.4672 0.1124
SK-BR-3 Gefitinib
3.33
uM
LJP6
1
N08
72
hr
1476 1869 3694 0.5060 0.1769
SK-BR-3 Gefitinib
3.33
uM
LJP6
2
N08
72
hr
1476 2074 3694 0.5614 0.2694
SK-BR-3 Gefitinib
3.33
uM
LJP6
3
N08
72
hr
1476 2136 3694 0.5782 0.2973
SK-BR-3 Geldanamycin
3.33
uM
LJP5
1
O02
72
hr
1476 1293 3694 0.3500 -0.0829