LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 YM 201636
1.11
uM
LJP5
2
N09
72
hr
1476 3260 3694 0.8825 0.8043
SK-BR-3 YM 201636
1.11
uM
LJP5
3
N09
72
hr
1476 3195 3694 0.8649 0.7749
SK-BR-3 ZSTK474
1.11
uM
LJP6
1
M15
72
hr
1476 1421 3694 0.3847 -0.0251
SK-BR-3 ZSTK474
1.11
uM
LJP6
2
M15
72
hr
1476 1588 3694 0.4299 0.0502
SK-BR-3 ZSTK474
1.11
uM
LJP6
3
M15
72
hr
1476 1716 3694 0.4645 0.1079
SK-BR-3 Afatinib
3.33
uM
LJP6
1
G20
72
hr
1476 1408 3694 0.3812 -0.0310
SK-BR-3 Afatinib
3.33
uM
LJP6
2
G20
72
hr
1476 1506 3694 0.4077 0.0132
SK-BR-3 Afatinib
3.33
uM
LJP6
3
G20
72
hr
1476 1538 3694 0.4164 0.0276
SK-BR-3 Sigma A6730
3.33
uM
LJP5
1
B20
72
hr
1476 2834 3694 0.7672 0.6121
SK-BR-3 Sigma A6730
3.33
uM
LJP5
2
B20
72
hr
1476 2756 3694 0.7461 0.5770
SK-BR-3 Sigma A6730
3.33
uM
LJP5
3
B20
72
hr
1476 2580 3694 0.6984 0.4976
SK-BR-3 Alvocidib
3.33
uM
LJP6
1
A14
72
hr
1476 1229 3694 0.3327 -0.1117
SK-BR-3 Alvocidib
3.33
uM
LJP6
2
A14
72
hr
1476 1047 3694 0.2834 -0.1938
SK-BR-3 Alvocidib
3.33
uM
LJP6
3
A14
72
hr
1476 965 3694 0.2612 -0.2308
SK-BR-3 AT-7519
3.33
uM
LJP6
1
K02
72
hr
1476 1113 3694 0.3013 -0.1640
SK-BR-3 AT-7519
3.33
uM
LJP6
2
K02
72
hr
1476 976 3694 0.2642 -0.2258
SK-BR-3 AT-7519
3.33
uM
LJP6
3
K02
72
hr
1476 860 3694 0.2328 -0.2781
SK-BR-3 AZD 5438
3.33
uM
LJP6
1
J02
72
hr
1476 1060 3694 0.2870 -0.1879
SK-BR-3 AZD 5438
3.33
uM
LJP6
2
J02
72
hr
1476 1117 3694 0.3024 -0.1622
SK-BR-3 AZD 5438
3.33
uM
LJP6
3
J02
72
hr
1476 1074 3694 0.2907 -0.1816
SK-BR-3 AZD-6482
3.33
uM
LJP5
1
I02
72
hr
1476 2173 3694 0.5882 0.3140
SK-BR-3 AZD-6482
3.33
uM
LJP5
2
I02
72
hr
1476 2333 3694 0.6316 0.3862
SK-BR-3 AZD-6482
3.33
uM
LJP5
3
I02
72
hr
1476 2527 3694 0.6841 0.4737
SK-BR-3 AZD7762
3.33
uM
LJP6
1
L02
72
hr
1476 802 3694 0.2171 -0.3043
SK-BR-3 AZD7762
3.33
uM
LJP6
2
L02
72
hr
1476 1189 3694 0.3219 -0.1298