LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 2 | O21 | 72 | hr | 1476 | 1188 | 3694 | 0.3216 | -0.1302 |
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 3 | O21 | 72 | hr | 1476 | 1150 | 3694 | 0.3113 | -0.1474 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 1 | K09 | 72 | hr | 1476 | 1886 | 3694 | 0.5106 | 0.1846 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 2 | K09 | 72 | hr | 1476 | 1555 | 3694 | 0.4210 | 0.0353 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 3 | K09 | 72 | hr | 1476 | 1652 | 3694 | 0.4472 | 0.0791 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 1 | K09 | 72 | hr | 1476 | 1545 | 3694 | 0.4182 | 0.0308 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 2 | K09 | 72 | hr | 1476 | 1560 | 3694 | 0.4223 | 0.0376 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 3 | K09 | 72 | hr | 1476 | 1626 | 3694 | 0.4402 | 0.0673 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1476 | 3329 | 3694 | 0.9012 | 0.8354 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 2 | J03 | 72 | hr | 1476 | 3287 | 3694 | 0.8898 | 0.8164 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1476 | 3260 | 3694 | 0.8825 | 0.8043 |
| SK-BR-3 | Ruxolitinib | 1.11 | uM | LJP5 | 1 | O15 | 72 | hr | 1476 | 3551 | 3694 | 0.9613 | 0.9355 |
| SK-BR-3 | Ruxolitinib | 1.11 | uM | LJP5 | 2 | O15 | 72 | hr | 1476 | 3699 | 3694 | 1.0013 | 1.0022 |
| SK-BR-3 | Ruxolitinib | 1.11 | uM | LJP5 | 3 | O15 | 72 | hr | 1476 | 3560 | 3694 | 0.9637 | 0.9395 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1476 | 4824 | 3694 | 1.3059 | 1.5096 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 2 | G09 | 72 | hr | 1476 | 4091 | 3694 | 1.1075 | 1.1790 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 3 | G09 | 72 | hr | 1476 | 4524 | 3694 | 1.2247 | 1.3743 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 1 | D09 | 72 | hr | 1476 | 3417 | 3694 | 0.9250 | 0.8751 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 2 | D09 | 72 | hr | 1476 | 3070 | 3694 | 0.8311 | 0.7186 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 3 | D09 | 72 | hr | 1476 | 3669 | 3694 | 0.9932 | 0.9887 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 1 | M09 | 72 | hr | 1476 | 3720 | 3694 | 1.0070 | 1.0117 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 2 | M09 | 72 | hr | 1476 | 3809 | 3694 | 1.0311 | 1.0518 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 3 | M09 | 72 | hr | 1476 | 3828 | 3694 | 1.0363 | 1.0604 |
| SK-BR-3 | Sirolimus | 1.11 | uM | LJP6 | 1 | L15 | 72 | hr | 1476 | 1451 | 3694 | 0.3928 | -0.0116 |
| SK-BR-3 | Sirolimus | 1.11 | uM | LJP6 | 2 | L15 | 72 | hr | 1476 | 2611 | 3694 | 0.7068 | 0.5116 |