LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 1 | D23 | 72 | hr | 1476 | 1246 | 3694 | 0.3373 | -0.1041 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 2 | D23 | 72 | hr | 1476 | 1187 | 3694 | 0.3213 | -0.1307 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 3 | D23 | 72 | hr | 1476 | 1271 | 3694 | 0.3441 | -0.0928 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 1 | P11 | 72 | hr | 1476 | 2845 | 3694 | 0.7702 | 0.6171 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 2 | P11 | 72 | hr | 1476 | 2810 | 3694 | 0.7607 | 0.6013 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 3 | P11 | 72 | hr | 1476 | 2880 | 3694 | 0.7796 | 0.6329 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 1 | P05 | 72 | hr | 1476 | 3383 | 3694 | 0.9158 | 0.8597 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 2 | P05 | 72 | hr | 1476 | 3272 | 3694 | 0.8858 | 0.8097 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 3 | P05 | 72 | hr | 1476 | 3311 | 3694 | 0.8963 | 0.8273 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 1 | N11 | 72 | hr | 1476 | 3516 | 3694 | 0.9518 | 0.9197 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 2 | N11 | 72 | hr | 1476 | 3748 | 3694 | 1.0146 | 1.0243 |
| SK-BR-3 | YM 201636 | 0.12 | uM | LJP5 | 3 | N11 | 72 | hr | 1476 | 3790 | 3694 | 1.0260 | 1.0433 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 1 | M17 | 72 | hr | 1476 | 2249 | 3694 | 0.6088 | 0.3483 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 2 | M17 | 72 | hr | 1476 | 2576 | 3694 | 0.6973 | 0.4958 |
| SK-BR-3 | ZSTK474 | 0.12 | uM | LJP6 | 3 | M17 | 72 | hr | 1476 | 2480 | 3694 | 0.6714 | 0.4525 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 1 | G22 | 72 | hr | 1476 | 1370 | 3694 | 0.3709 | -0.0481 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 2 | G22 | 72 | hr | 1476 | 1293 | 3694 | 0.3500 | -0.0829 |
| SK-BR-3 | Afatinib | 0.37 | uM | LJP6 | 3 | G22 | 72 | hr | 1476 | 1498 | 3694 | 0.4055 | 0.0096 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 1 | B22 | 72 | hr | 1476 | 3152 | 3694 | 0.8533 | 0.7555 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 2 | B22 | 72 | hr | 1476 | 3191 | 3694 | 0.8638 | 0.7731 |
| SK-BR-3 | Sigma A6730 | 0.37 | uM | LJP5 | 3 | B22 | 72 | hr | 1476 | 3185 | 3694 | 0.8622 | 0.7704 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 1 | A16 | 72 | hr | 1476 | 1357 | 3694 | 0.3674 | -0.0540 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 2 | A16 | 72 | hr | 1476 | 1255 | 3694 | 0.3397 | -0.1000 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 1476 | 1064 | 3694 | 0.2880 | -0.1861 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 1476 | 1400 | 3694 | 0.3790 | -0.0346 |