LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 1 | D17 | 72 | hr | 1476 | 1425 | 3694 | 0.3858 | -0.0233 |
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 2 | D17 | 72 | hr | 1476 | 1543 | 3694 | 0.4177 | 0.0299 |
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 3 | D17 | 72 | hr | 1476 | 1335 | 3694 | 0.3614 | -0.0639 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 1 | D05 | 72 | hr | 1476 | 3881 | 3694 | 1.0506 | 1.0843 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 2 | D05 | 72 | hr | 1476 | 3807 | 3694 | 1.0306 | 1.0509 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 3 | D05 | 72 | hr | 1476 | 3924 | 3694 | 1.0622 | 1.1037 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 1476 | 974 | 3694 | 0.2637 | -0.2267 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 2 | H17 | 72 | hr | 1476 | 1044 | 3694 | 0.2826 | -0.1952 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 3 | H17 | 72 | hr | 1476 | 1001 | 3694 | 0.2710 | -0.2146 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1476 | 1510 | 3694 | 0.4088 | 0.0150 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 2 | K23 | 72 | hr | 1476 | 1475 | 3694 | 0.3993 | -0.0008 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 3 | K23 | 72 | hr | 1476 | 1502 | 3694 | 0.4066 | 0.0114 |
| SK-BR-3 | NVP-AEW541 | 0.12 | uM | LJP5 | 1 | E17 | 72 | hr | 1476 | 3905 | 3694 | 1.0571 | 1.0951 |
| SK-BR-3 | NVP-AEW541 | 0.12 | uM | LJP5 | 2 | E17 | 72 | hr | 1476 | 4058 | 3694 | 1.0985 | 1.1641 |
| SK-BR-3 | NVP-AEW541 | 0.12 | uM | LJP5 | 3 | E17 | 72 | hr | 1476 | 4194 | 3694 | 1.1353 | 1.2255 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 1 | L17 | 72 | hr | 1476 | 4276 | 3694 | 1.1575 | 1.2625 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 2 | L17 | 72 | hr | 1476 | 4187 | 3694 | 1.1334 | 1.2223 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 3 | L17 | 72 | hr | 1476 | 4214 | 3694 | 1.1408 | 1.2345 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 1 | K17 | 72 | hr | 1476 | 4088 | 3694 | 1.1066 | 1.1777 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 2 | K17 | 72 | hr | 1476 | 3937 | 3694 | 1.0658 | 1.1096 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 3 | K17 | 72 | hr | 1476 | 4268 | 3694 | 1.1554 | 1.2588 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 1 | C11 | 72 | hr | 1476 | 3135 | 3694 | 0.8487 | 0.7479 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 2 | C11 | 72 | hr | 1476 | 3626 | 3694 | 0.9816 | 0.9693 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 3 | C11 | 72 | hr | 1476 | 3710 | 3694 | 1.0043 | 1.0072 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 1476 | 3083 | 3694 | 0.8346 | 0.7244 |