LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 2 | A15 | 72 | hr | 1235 | 2561 | 4156 | 0.6162 | 0.4539 |
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 3 | A15 | 72 | hr | 1235 | 2360 | 4156 | 0.5678 | 0.3850 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 1 | N15 | 72 | hr | 1235 | 3657 | 4156 | 0.8799 | 0.8291 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 2 | N15 | 72 | hr | 1235 | 4267 | 4156 | 1.0267 | 1.0379 |
| MCF7 | Nilotinib | 1.11 | uM | LJP5 | 3 | N15 | 72 | hr | 1235 | 4516 | 4156 | 1.0866 | 1.1232 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 1 | H03 | 72 | hr | 1235 | 2225 | 4156 | 0.5354 | 0.3388 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 2 | H03 | 72 | hr | 1235 | 2000 | 4156 | 0.4812 | 0.2618 |
| MCF7 | Nintedanib | 1.11 | uM | LJP6 | 3 | H03 | 72 | hr | 1235 | 2134 | 4156 | 0.5135 | 0.3077 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 1 | C09 | 72 | hr | 1235 | 3684 | 4156 | 0.8864 | 0.8383 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 2 | C09 | 72 | hr | 1235 | 3781 | 4156 | 0.9097 | 0.8716 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 3 | C09 | 72 | hr | 1235 | 3885 | 4156 | 0.9348 | 0.9072 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 1 | M15 | 72 | hr | 1235 | 1353 | 4156 | 0.3255 | 0.0403 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 2 | M15 | 72 | hr | 1235 | 1376 | 4156 | 0.3311 | 0.0481 |
| MCF7 | Dactolisib | 1.11 | uM | LJP5 | 3 | M15 | 72 | hr | 1235 | 1386 | 4156 | 0.3335 | 0.0516 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 1 | K15 | 72 | hr | 1235 | 1205 | 4156 | 0.2899 | -0.0104 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 2 | K15 | 72 | hr | 1235 | 925 | 4156 | 0.2226 | -0.1063 |
| MCF7 | NVP-TAE684 | 1.11 | uM | LJP6 | 3 | K15 | 72 | hr | 1235 | 1067 | 4156 | 0.2567 | -0.0577 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 1 | E15 | 72 | hr | 1235 | 1787 | 4156 | 0.4300 | 0.1889 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 2 | E15 | 72 | hr | 1235 | 1757 | 4156 | 0.4228 | 0.1786 |
| MCF7 | Palbociclib | 1.11 | uM | LJP6 | 3 | E15 | 72 | hr | 1235 | 1838 | 4156 | 0.4422 | 0.2063 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 1 | C03 | 72 | hr | 1235 | 2255 | 4156 | 0.5426 | 0.3491 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 2 | C03 | 72 | hr | 1235 | 2521 | 4156 | 0.6066 | 0.4402 |
| MCF7 | PD0325901 | 1.11 | uM | LJP5 | 3 | C03 | 72 | hr | 1235 | 2530 | 4156 | 0.6087 | 0.4432 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 1 | E03 | 72 | hr | 1235 | 2223 | 4156 | 0.5349 | 0.3381 |
| MCF7 | PD0325901 | 1.11 | uM | LJP6 | 2 | E03 | 72 | hr | 1235 | 2272 | 4156 | 0.5467 | 0.3549 |