LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 TGX221
0.04
uM
LJP5
1
H24
72
hr
1657 5532 5505 1.0048 1.0068
BT-20 TGX221
0.04
uM
LJP5
2
H24
72
hr
1657 4894 5505 0.8889 0.8410
BT-20 TGX221
0.04
uM
LJP5
3
H24
72
hr
1657 5322 5505 0.9666 0.9523
BT-20 Torin1
0.04
uM
LJP6
1
O18
72
hr
1657 2261 5505 0.4107 0.1568
BT-20 Torin1
0.04
uM
LJP6
2
O18
72
hr
1657 2593 5505 0.4710 0.2431
BT-20 Torin1
0.04
uM
LJP6
3
O18
72
hr
1657 2482 5505 0.4508 0.2142
BT-20 Torin2
0.04
uM
LJP5
1
I24
72
hr
1657 1771 5505 0.3217 0.0294
BT-20 Torin2
0.04
uM
LJP5
2
I24
72
hr
1657 1690 5505 0.3070 0.0084
BT-20 Torin2
0.04
uM
LJP5
3
I24
72
hr
1657 1732 5505 0.3146 0.0193
BT-20 Tozasertib
0.04
uM
LJP5
1
B18
72
hr
1657 3624 5505 0.6582 0.5110
BT-20 Tozasertib
0.04
uM
LJP5
2
B18
72
hr
1657 2951 5505 0.5360 0.3361
BT-20 Tozasertib
0.04
uM
LJP5
3
B18
72
hr
1657 3463 5505 0.6290 0.4692
BT-20 Trametinib
0.04
uM
LJP5
1
P24
72
hr
1657 4104 5505 0.7454 0.6357
BT-20 Trametinib
0.04
uM
LJP5
2
P24
72
hr
1657 4134 5505 0.7509 0.6435
BT-20 Trametinib
0.04
uM
LJP5
3
P24
72
hr
1657 3889 5505 0.7064 0.5799
BT-20 TWS119
0.04
uM
LJP5
1
M06
72
hr
1657 5266 5505 0.9565 0.9377
BT-20 TWS119
0.04
uM
LJP5
2
M06
72
hr
1657 5976 5505 1.0854 1.1222
BT-20 TWS119
0.04
uM
LJP5
3
M06
72
hr
1657 5421 5505 0.9846 0.9780
BT-20 Vemurafenib
0.04
uM
LJP5
1
C18
72
hr
1657 5409 5505 0.9824 0.9749
BT-20 Vemurafenib
0.04
uM
LJP5
2
C18
72
hr
1657 5507 5505 1.0002 1.0003
BT-20 Vemurafenib
0.04
uM
LJP5
3
C18
72
hr
1657 6282 5505 1.1410 1.2018
BT-20 Withaferin A
0.04
uM
LJP5
1
G18
72
hr
1657 5964 5505 1.0832 1.1191
BT-20 Withaferin A
0.04
uM
LJP5
2
G18
72
hr
1657 5318 5505 0.9659 0.9512
BT-20 Withaferin A
0.04
uM
LJP5
3
G18
72
hr
1657 5801 5505 1.0536 1.0768
BT-20 Withaferin A
0.04
uM
LJP6
1
G18
72
hr
1657 5764 5505 1.0469 1.0671