LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | PD0325901 | 10.0 | uM | LJP5 | 1 | C01 | 72 | hr | 1657 | 3014 | 5505 | 0.5474 | 0.3525 |
| BT-20 | PD0325901 | 10.0 | uM | LJP5 | 2 | C01 | 72 | hr | 1657 | 3182 | 5505 | 0.5780 | 0.3961 |
| BT-20 | PD0325901 | 10.0 | uM | LJP5 | 3 | C01 | 72 | hr | 1657 | 3381 | 5505 | 0.6141 | 0.4478 |
| BT-20 | PD0325901 | 10.0 | uM | LJP6 | 1 | E01 | 72 | hr | 1657 | 3158 | 5505 | 0.5736 | 0.3899 |
| BT-20 | PD0325901 | 10.0 | uM | LJP6 | 2 | E01 | 72 | hr | 1657 | 2999 | 5505 | 0.5447 | 0.3486 |
| BT-20 | PD0325901 | 10.0 | uM | LJP6 | 3 | E01 | 72 | hr | 1657 | 3314 | 5505 | 0.6019 | 0.4304 |
| BT-20 | PD173074 | 10.0 | uM | LJP6 | 1 | I07 | 72 | hr | 1657 | 5394 | 5505 | 0.9797 | 0.9710 |
| BT-20 | PD173074 | 10.0 | uM | LJP6 | 2 | I07 | 72 | hr | 1657 | 5763 | 5505 | 1.0467 | 1.0669 |
| BT-20 | PD173074 | 10.0 | uM | LJP6 | 3 | I07 | 72 | hr | 1657 | 5353 | 5505 | 0.9723 | 0.9603 |
| BT-20 | PD184352 | 10.0 | uM | LJP5 | 1 | L07 | 72 | hr | 1657 | 3095 | 5505 | 0.5622 | 0.3735 |
| BT-20 | PD184352 | 10.0 | uM | LJP5 | 2 | L07 | 72 | hr | 1657 | 2841 | 5505 | 0.5160 | 0.3075 |
| BT-20 | PD184352 | 10.0 | uM | LJP5 | 3 | L07 | 72 | hr | 1657 | 3026 | 5505 | 0.5496 | 0.3556 |
| BT-20 | Pelitinib | 10.0 | uM | LJP5 | 1 | I13 | 72 | hr | 1657 | 1197 | 5505 | 0.2174 | -0.1197 |
| BT-20 | Pelitinib | 10.0 | uM | LJP5 | 2 | I13 | 72 | hr | 1657 | 1244 | 5505 | 0.2260 | -0.1075 |
| BT-20 | Pelitinib | 10.0 | uM | LJP5 | 3 | I13 | 72 | hr | 1657 | 1167 | 5505 | 0.2120 | -0.1275 |
| BT-20 | PF431396 | 10.0 | uM | LJP5 | 1 | E07 | 72 | hr | 1657 | 1659 | 5505 | 0.3013 | 0.0003 |
| BT-20 | PF431396 | 10.0 | uM | LJP5 | 2 | E07 | 72 | hr | 1657 | 1611 | 5505 | 0.2926 | -0.0121 |
| BT-20 | PF431396 | 10.0 | uM | LJP5 | 3 | E07 | 72 | hr | 1657 | 1848 | 5505 | 0.3357 | 0.0494 |
| BT-20 | PF477736 | 10.0 | uM | LJP5 | 1 | J19 | 72 | hr | 1657 | 2036 | 5505 | 0.3698 | 0.0983 |
| BT-20 | PF477736 | 10.0 | uM | LJP5 | 2 | J19 | 72 | hr | 1657 | 2098 | 5505 | 0.3811 | 0.1144 |
| BT-20 | PF477736 | 10.0 | uM | LJP5 | 3 | J19 | 72 | hr | 1657 | 2208 | 5505 | 0.4010 | 0.1430 |
| BT-20 | PF562271 | 10.0 | uM | LJP6 | 1 | F13 | 72 | hr | 1657 | 1266 | 5505 | 0.2299 | -0.1018 |
| BT-20 | PF562271 | 10.0 | uM | LJP6 | 2 | F13 | 72 | hr | 1657 | 1149 | 5505 | 0.2087 | -0.1322 |
| BT-20 | PF562271 | 10.0 | uM | LJP6 | 3 | F13 | 72 | hr | 1657 | 1490 | 5505 | 0.2706 | -0.0436 |
| BT-20 | PHA-665752 | 10.0 | uM | LJP5 | 1 | F13 | 72 | hr | 1657 | 4022 | 5505 | 0.7305 | 0.6144 |