LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 1657 5162 5505 0.9376 0.9107
BT-20 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1657 797 5505 0.1448 -0.2237
BT-20 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1657 895 5505 0.1626 -0.1982
BT-20 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1657 1031 5505 0.1873 -0.1629
BT-20 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1657 812 5505 0.1475 -0.2198
BT-20 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1657 768 5505 0.1395 -0.2312
BT-20 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1657 1124 5505 0.2042 -0.1387
BT-20 WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 1657 2243 5505 0.4074 0.1521
BT-20 WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 1657 2195 5505 0.3987 0.1396
BT-20 WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 1657 2210 5505 0.4014 0.1435
BT-20 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 1657 1354 5505 0.2459 -0.0789
BT-20 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 1657 1322 5505 0.2401 -0.0873
BT-20 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 1657 1436 5505 0.2608 -0.0576
BT-20 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 1657 3612 5505 0.6561 0.5079
BT-20 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 1657 3363 5505 0.6108 0.4432
BT-20 XMD11-50
3.33
uM
LJP6
 3
P08
 72
hr
 1657 3385 5505 0.6148 0.4489
BT-20 Y39983
3.33
uM
LJP6
 1
P02
 72
hr
 1657 4369 5505 0.7936 0.7046
BT-20 Y39983
3.33
uM
LJP6
 2
P02
 72
hr
 1657 4158 5505 0.7552 0.6498
BT-20 Y39983
3.33
uM
LJP6
 3
P02
 72
hr
 1657 4386 5505 0.7966 0.7090
BT-20 YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 1657 4177 5505 0.7587 0.6547
BT-20 YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 1657 3805 5505 0.6911 0.5580
BT-20 YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 1657 3892 5505 0.7069 0.5806
BT-20 ZSTK474
3.33
uM
LJP6
 1
M14
 72
hr
 1657 1591 5505 0.2890 -0.0173
BT-20 ZSTK474
3.33
uM
LJP6
 2
M14
 72
hr
 1657 1785 5505 0.3242 0.0331
BT-20 ZSTK474
3.33
uM
LJP6
 3
M14
 72
hr
 1657 1716 5505 0.3117 0.0151