LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Withaferin A
10.0
uM
LJP6
 2
G13
 72
hr
 1657 1035 5505 0.1880 -0.1618
BT-20 Withaferin A
10.0
uM
LJP6
 3
G13
 72
hr
 1657 1044 5505 0.1896 -0.1595
BT-20 WYE-125132
10.0
uM
LJP6
 1
L07
 72
hr
 1657 1988 5505 0.3611 0.0858
BT-20 WYE-125132
10.0
uM
LJP6
 2
L07
 72
hr
 1657 2068 5505 0.3756 0.1066
BT-20 WYE-125132
10.0
uM
LJP6
 3
L07
 72
hr
 1657 2002 5505 0.3636 0.0895
BT-20 WZ3105
10.0
uM
LJP5
 1
D19
 72
hr
 1657 1044 5505 0.1896 -0.1595
BT-20 WZ3105
10.0
uM
LJP5
 2
D19
 72
hr
 1657 1094 5505 0.1987 -0.1465
BT-20 WZ3105
10.0
uM
LJP5
 3
D19
 72
hr
 1657 1242 5505 0.2256 -0.1080
BT-20 XMD11-50
10.0
uM
LJP6
 1
P07
 72
hr
 1657 2406 5505 0.4370 0.1945
BT-20 XMD11-50
10.0
uM
LJP6
 2
P07
 72
hr
 1657 2449 5505 0.4448 0.2056
BT-20 XMD11-50
10.0
uM
LJP6
 3
P07
 72
hr
 1657 2245 5505 0.4078 0.1526
BT-20 Y39983
10.0
uM
LJP6
 1
P01
 72
hr
 1657 2169 5505 0.3940 0.1329
BT-20 Y39983
10.0
uM
LJP6
 2
P01
 72
hr
 1657 2109 5505 0.3831 0.1173
BT-20 Y39983
10.0
uM
LJP6
 3
P01
 72
hr
 1657 2459 5505 0.4466 0.2082
BT-20 YM 201636
10.0
uM
LJP5
 1
N07
 72
hr
 1657 2187 5505 0.3972 0.1375
BT-20 YM 201636
10.0
uM
LJP5
 2
N07
 72
hr
 1657 2236 5505 0.4061 0.1503
BT-20 YM 201636
10.0
uM
LJP5
 3
N07
 72
hr
 1657 2005 5505 0.3642 0.0902
BT-20 ZSTK474
10.0
uM
LJP6
 1
M13
 72
hr
 1657 1302 5505 0.2365 -0.0925
BT-20 ZSTK474
10.0
uM
LJP6
 2
M13
 72
hr
 1657 1617 5505 0.2937 -0.0106
BT-20 ZSTK474
10.0
uM
LJP6
 3
M13
 72
hr
 1657 1711 5505 0.3108 0.0138
Hs 578T Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 929 3002 3228 0.9300 0.9017
Hs 578T Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 929 3085 3228 0.9557 0.9378
Hs 578T Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 929 3122 3228 0.9671 0.9539
Hs 578T Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 929 3126 3228 0.9684 0.9556
Hs 578T Sigma A6730
0.04
uM
LJP5
 2
B24
 72
hr
 929 3283 3228 1.0170 1.0239