LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | Dasatinib | 3.33 | uM | LJP6 | 1 | I02 | 72 | hr | 1657 | 1218 | 5505 | 0.2212 | -0.1143 |
BT-20 | Dasatinib | 3.33 | uM | LJP6 | 2 | I02 | 72 | hr | 1657 | 1080 | 5505 | 0.1962 | -0.1501 |
BT-20 | Dasatinib | 3.33 | uM | LJP6 | 3 | I02 | 72 | hr | 1657 | 1181 | 5505 | 0.2145 | -0.1239 |
BT-20 | Dovitinib | 3.33 | uM | LJP5 | 1 | E20 | 72 | hr | 1657 | 2735 | 5505 | 0.4968 | 0.2800 |
BT-20 | Dovitinib | 3.33 | uM | LJP5 | 2 | E20 | 72 | hr | 1657 | 2353 | 5505 | 0.4274 | 0.1807 |
BT-20 | Dovitinib | 3.33 | uM | LJP5 | 3 | E20 | 72 | hr | 1657 | 2337 | 5505 | 0.4245 | 0.1765 |
BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 1 | D14 | 72 | hr | 1657 | 6685 | 5505 | 1.2142 | 1.3065 |
BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 2 | D14 | 72 | hr | 1657 | 6099 | 5505 | 1.1078 | 1.1542 |
BT-20 | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 1657 | 6985 | 5505 | 1.2687 | 1.3844 |
BT-20 | Erlotinib | 3.33 | uM | LJP5 | 1 | M20 | 72 | hr | 1657 | 4768 | 5505 | 0.8660 | 0.8083 |
BT-20 | Erlotinib | 3.33 | uM | LJP5 | 2 | M20 | 72 | hr | 1657 | 4919 | 5505 | 0.8934 | 0.8475 |
BT-20 | Erlotinib | 3.33 | uM | LJP5 | 3 | M20 | 72 | hr | 1657 | 4795 | 5505 | 0.8709 | 0.8153 |
BT-20 | Foretinib | 3.33 | uM | LJP5 | 1 | H08 | 72 | hr | 1657 | 1559 | 5505 | 0.2832 | -0.0257 |
BT-20 | Foretinib | 3.33 | uM | LJP5 | 2 | H08 | 72 | hr | 1657 | 1672 | 5505 | 0.3037 | 0.0037 |
BT-20 | Foretinib | 3.33 | uM | LJP5 | 3 | H08 | 72 | hr | 1657 | 1642 | 5505 | 0.2982 | -0.0041 |
BT-20 | R406 | 3.33 | uM | LJP6 | 1 | C14 | 72 | hr | 1657 | 4918 | 5505 | 0.8933 | 0.8473 |
BT-20 | R406 | 3.33 | uM | LJP6 | 2 | C14 | 72 | hr | 1657 | 4844 | 5505 | 0.8798 | 0.8281 |
BT-20 | R406 | 3.33 | uM | LJP6 | 3 | C14 | 72 | hr | 1657 | 5137 | 5505 | 0.9330 | 0.9042 |
BT-20 | Pictilisib | 3.33 | uM | LJP6 | 1 | D20 | 72 | hr | 1657 | 1675 | 5505 | 0.3042 | 0.0045 |
BT-20 | Pictilisib | 3.33 | uM | LJP6 | 2 | D20 | 72 | hr | 1657 | 1815 | 5505 | 0.3297 | 0.0409 |
BT-20 | Pictilisib | 3.33 | uM | LJP6 | 3 | D20 | 72 | hr | 1657 | 1750 | 5505 | 0.3179 | 0.0240 |
BT-20 | Gefitinib | 3.33 | uM | LJP6 | 1 | N08 | 72 | hr | 1657 | 4837 | 5505 | 0.8786 | 0.8262 |
BT-20 | Gefitinib | 3.33 | uM | LJP6 | 2 | N08 | 72 | hr | 1657 | 4975 | 5505 | 0.9036 | 0.8621 |
BT-20 | Gefitinib | 3.33 | uM | LJP6 | 3 | N08 | 72 | hr | 1657 | 4760 | 5505 | 0.8646 | 0.8062 |
BT-20 | Geldanamycin | 3.33 | uM | LJP5 | 1 | O02 | 72 | hr | 1657 | 1783 | 5505 | 0.3239 | 0.0326 |