LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
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BT-20 | YM 201636 | 1.11 | uM | LJP5 | 2 | N09 | 72 | hr | 1657 | 5082 | 5505 | 0.9231 | 0.8899 |
BT-20 | YM 201636 | 1.11 | uM | LJP5 | 3 | N09 | 72 | hr | 1657 | 4514 | 5505 | 0.8199 | 0.7423 |
BT-20 | ZSTK474 | 1.11 | uM | LJP6 | 1 | M15 | 72 | hr | 1657 | 2024 | 5505 | 0.3676 | 0.0952 |
BT-20 | ZSTK474 | 1.11 | uM | LJP6 | 2 | M15 | 72 | hr | 1657 | 2353 | 5505 | 0.4274 | 0.1807 |
BT-20 | ZSTK474 | 1.11 | uM | LJP6 | 3 | M15 | 72 | hr | 1657 | 2185 | 5505 | 0.3969 | 0.1370 |
BT-20 | Afatinib | 3.33 | uM | LJP6 | 1 | G20 | 72 | hr | 1657 | 4955 | 5505 | 0.9000 | 0.8569 |
BT-20 | Afatinib | 3.33 | uM | LJP6 | 2 | G20 | 72 | hr | 1657 | 5303 | 5505 | 0.9632 | 0.9473 |
BT-20 | Afatinib | 3.33 | uM | LJP6 | 3 | G20 | 72 | hr | 1657 | 4305 | 5505 | 0.7819 | 0.6880 |
BT-20 | Sigma A6730 | 3.33 | uM | LJP5 | 1 | B20 | 72 | hr | 1657 | 4988 | 5505 | 0.9060 | 0.8655 |
BT-20 | Sigma A6730 | 3.33 | uM | LJP5 | 2 | B20 | 72 | hr | 1657 | 4894 | 5505 | 0.8889 | 0.8410 |
BT-20 | Sigma A6730 | 3.33 | uM | LJP5 | 3 | B20 | 72 | hr | 1657 | 5450 | 5505 | 0.9899 | 0.9855 |
BT-20 | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1657 | 1164 | 5505 | 0.2114 | -0.1283 |
BT-20 | Alvocidib | 3.33 | uM | LJP6 | 2 | A14 | 72 | hr | 1657 | 1007 | 5505 | 0.1829 | -0.1691 |
BT-20 | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 1657 | 1394 | 5505 | 0.2532 | -0.0685 |
BT-20 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1657 | 1260 | 5505 | 0.2289 | -0.1034 |
BT-20 | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 1657 | 1094 | 5505 | 0.1987 | -0.1465 |
BT-20 | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1657 | 1297 | 5505 | 0.2356 | -0.0937 |
BT-20 | AZD 5438 | 3.33 | uM | LJP6 | 1 | J02 | 72 | hr | 1657 | 1653 | 5505 | 0.3002 | -0.0012 |
BT-20 | AZD 5438 | 3.33 | uM | LJP6 | 2 | J02 | 72 | hr | 1657 | 1503 | 5505 | 0.2730 | -0.0402 |
BT-20 | AZD 5438 | 3.33 | uM | LJP6 | 3 | J02 | 72 | hr | 1657 | 1815 | 5505 | 0.3297 | 0.0409 |
BT-20 | AZD-6482 | 3.33 | uM | LJP5 | 1 | I02 | 72 | hr | 1657 | 2316 | 5505 | 0.4207 | 0.1711 |
BT-20 | AZD-6482 | 3.33 | uM | LJP5 | 2 | I02 | 72 | hr | 1657 | 2605 | 5505 | 0.4732 | 0.2462 |
BT-20 | AZD-6482 | 3.33 | uM | LJP5 | 3 | I02 | 72 | hr | 1657 | 2463 | 5505 | 0.4474 | 0.2093 |
BT-20 | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 1657 | 1660 | 5505 | 0.3015 | 0.0006 |
BT-20 | AZD7762 | 3.33 | uM | LJP6 | 2 | L02 | 72 | hr | 1657 | 1615 | 5505 | 0.2933 | -0.0111 |