LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 YM 201636
1.11
uM
LJP5
2
N09
72
hr
1657 5082 5505 0.9231 0.8899
BT-20 YM 201636
1.11
uM
LJP5
3
N09
72
hr
1657 4514 5505 0.8199 0.7423
BT-20 ZSTK474
1.11
uM
LJP6
1
M15
72
hr
1657 2024 5505 0.3676 0.0952
BT-20 ZSTK474
1.11
uM
LJP6
2
M15
72
hr
1657 2353 5505 0.4274 0.1807
BT-20 ZSTK474
1.11
uM
LJP6
3
M15
72
hr
1657 2185 5505 0.3969 0.1370
BT-20 Afatinib
3.33
uM
LJP6
1
G20
72
hr
1657 4955 5505 0.9000 0.8569
BT-20 Afatinib
3.33
uM
LJP6
2
G20
72
hr
1657 5303 5505 0.9632 0.9473
BT-20 Afatinib
3.33
uM
LJP6
3
G20
72
hr
1657 4305 5505 0.7819 0.6880
BT-20 Sigma A6730
3.33
uM
LJP5
1
B20
72
hr
1657 4988 5505 0.9060 0.8655
BT-20 Sigma A6730
3.33
uM
LJP5
2
B20
72
hr
1657 4894 5505 0.8889 0.8410
BT-20 Sigma A6730
3.33
uM
LJP5
3
B20
72
hr
1657 5450 5505 0.9899 0.9855
BT-20 Alvocidib
3.33
uM
LJP6
1
A14
72
hr
1657 1164 5505 0.2114 -0.1283
BT-20 Alvocidib
3.33
uM
LJP6
2
A14
72
hr
1657 1007 5505 0.1829 -0.1691
BT-20 Alvocidib
3.33
uM
LJP6
3
A14
72
hr
1657 1394 5505 0.2532 -0.0685
BT-20 AT-7519
3.33
uM
LJP6
1
K02
72
hr
1657 1260 5505 0.2289 -0.1034
BT-20 AT-7519
3.33
uM
LJP6
2
K02
72
hr
1657 1094 5505 0.1987 -0.1465
BT-20 AT-7519
3.33
uM
LJP6
3
K02
72
hr
1657 1297 5505 0.2356 -0.0937
BT-20 AZD 5438
3.33
uM
LJP6
1
J02
72
hr
1657 1653 5505 0.3002 -0.0012
BT-20 AZD 5438
3.33
uM
LJP6
2
J02
72
hr
1657 1503 5505 0.2730 -0.0402
BT-20 AZD 5438
3.33
uM
LJP6
3
J02
72
hr
1657 1815 5505 0.3297 0.0409
BT-20 AZD-6482
3.33
uM
LJP5
1
I02
72
hr
1657 2316 5505 0.4207 0.1711
BT-20 AZD-6482
3.33
uM
LJP5
2
I02
72
hr
1657 2605 5505 0.4732 0.2462
BT-20 AZD-6482
3.33
uM
LJP5
3
I02
72
hr
1657 2463 5505 0.4474 0.2093
BT-20 AZD7762
3.33
uM
LJP6
1
L02
72
hr
1657 1660 5505 0.3015 0.0006
BT-20 AZD7762
3.33
uM
LJP6
2
L02
72
hr
1657 1615 5505 0.2933 -0.0111