LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 2 | G18 | 72 | hr | 1476 | 3655 | 3694 | 0.9894 | 0.9824 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 3 | G18 | 72 | hr | 1476 | 4214 | 3694 | 1.1408 | 1.2345 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 1 | L12 | 72 | hr | 1476 | 1405 | 3694 | 0.3803 | -0.0323 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 2 | L12 | 72 | hr | 1476 | 1896 | 3694 | 0.5133 | 0.1891 |
| SK-BR-3 | WYE-125132 | 0.04 | uM | LJP6 | 3 | L12 | 72 | hr | 1476 | 1967 | 3694 | 0.5325 | 0.2211 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 1 | D24 | 72 | hr | 1476 | 1179 | 3694 | 0.3192 | -0.1343 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 2 | D24 | 72 | hr | 1476 | 1065 | 3694 | 0.2883 | -0.1857 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 3 | D24 | 72 | hr | 1476 | 1098 | 3694 | 0.2972 | -0.1708 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 1 | P12 | 72 | hr | 1476 | 2790 | 3694 | 0.7553 | 0.5923 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 2 | P12 | 72 | hr | 1476 | 2721 | 3694 | 0.7366 | 0.5612 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 3 | P12 | 72 | hr | 1476 | 2667 | 3694 | 0.7220 | 0.5368 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 1 | P06 | 72 | hr | 1476 | 3191 | 3694 | 0.8638 | 0.7731 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 2 | P06 | 72 | hr | 1476 | 3496 | 3694 | 0.9464 | 0.9107 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 3 | P06 | 72 | hr | 1476 | 3156 | 3694 | 0.8544 | 0.7573 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 1 | N12 | 72 | hr | 1476 | 3823 | 3694 | 1.0349 | 1.0582 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 2 | N12 | 72 | hr | 1476 | 4015 | 3694 | 1.0869 | 1.1447 |
| SK-BR-3 | YM 201636 | 0.04 | uM | LJP5 | 3 | N12 | 72 | hr | 1476 | 4249 | 3694 | 1.1502 | 1.2503 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 1 | M18 | 72 | hr | 1476 | 2803 | 3694 | 0.7588 | 0.5981 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 2 | M18 | 72 | hr | 1476 | 3246 | 3694 | 0.8787 | 0.7979 |
| SK-BR-3 | ZSTK474 | 0.04 | uM | LJP6 | 3 | M18 | 72 | hr | 1476 | 3223 | 3694 | 0.8725 | 0.7876 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 1 | G23 | 72 | hr | 1476 | 1340 | 3694 | 0.3628 | -0.0617 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 2 | G23 | 72 | hr | 1476 | 1314 | 3694 | 0.3557 | -0.0734 |
| SK-BR-3 | Afatinib | 0.12 | uM | LJP6 | 3 | G23 | 72 | hr | 1476 | 1319 | 3694 | 0.3571 | -0.0711 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 1 | B23 | 72 | hr | 1476 | 3258 | 3694 | 0.8820 | 0.8033 |
| SK-BR-3 | Sigma A6730 | 0.12 | uM | LJP5 | 2 | B23 | 72 | hr | 1476 | 2986 | 3694 | 0.8083 | 0.6807 |