LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Torin1
0.12
uM
LJP6
 3
O17
 72
hr
 1657 2144 5505 0.3894 0.1264
BT-20 Torin2
0.12
uM
LJP5
 1
I23
 72
hr
 1657 1474 5505 0.2677 -0.0478
BT-20 Torin2
0.12
uM
LJP5
 2
I23
 72
hr
 1657 1486 5505 0.2699 -0.0446
BT-20 Torin2
0.12
uM
LJP5
 3
I23
 72
hr
 1657 1608 5505 0.2921 -0.0129
BT-20 Tozasertib
0.12
uM
LJP5
 1
B17
 72
hr
 1657 2087 5505 0.3791 0.1116
BT-20 Tozasertib
0.12
uM
LJP5
 2
B17
 72
hr
 1657 1737 5505 0.3155 0.0206
BT-20 Tozasertib
0.12
uM
LJP5
 3
B17
 72
hr
 1657 2114 5505 0.3840 0.1186
BT-20 Trametinib
0.12
uM
LJP5
 1
P23
 72
hr
 1657 4137 5505 0.7514 0.6443
BT-20 Trametinib
0.12
uM
LJP5
 2
P23
 72
hr
 1657 4629 5505 0.8408 0.7722
BT-20 Trametinib
0.12
uM
LJP5
 3
P23
 72
hr
 1657 4481 5505 0.8139 0.7337
BT-20 TWS119
0.12
uM
LJP5
 1
M05
 72
hr
 1657 4928 5505 0.8951 0.8499
BT-20 TWS119
0.12
uM
LJP5
 2
M05
 72
hr
 1657 5544 5505 1.0070 1.0100
BT-20 TWS119
0.12
uM
LJP5
 3
M05
 72
hr
 1657 5571 5505 1.0119 1.0170
BT-20 Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 1657 5644 5505 1.0251 1.0360
BT-20 Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 1657 5658 5505 1.0277 1.0396
BT-20 Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 1657 5848 5505 1.0622 1.0890
BT-20 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1657 5479 5505 0.9952 0.9931
BT-20 Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1657 5523 5505 1.0031 1.0045
BT-20 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1657 5390 5505 0.9790 0.9699
BT-20 Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 1657 5294 5505 0.9616 0.9450
BT-20 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 1657 5233 5505 0.9505 0.9291
BT-20 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 1657 5539 5505 1.0061 1.0087
BT-20 WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 1657 2654 5505 0.4821 0.2589
BT-20 WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 1657 2550 5505 0.4632 0.2319
BT-20 WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 1657 2455 5505 0.4459 0.2072