LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | BI-2536 | 0.12 | uM | LJP6 | 1 | D17 | 72 | hr | 1657 | 1556 | 5505 | 0.2826 | -0.0264 |
| BT-20 | BI-2536 | 0.12 | uM | LJP6 | 2 | D17 | 72 | hr | 1657 | 1510 | 5505 | 0.2743 | -0.0384 |
| BT-20 | BI-2536 | 0.12 | uM | LJP6 | 3 | D17 | 72 | hr | 1657 | 1467 | 5505 | 0.2665 | -0.0496 |
| BT-20 | BMS345541 | 0.12 | uM | LJP6 | 1 | D05 | 72 | hr | 1657 | 5661 | 5505 | 1.0282 | 1.0404 |
| BT-20 | BMS345541 | 0.12 | uM | LJP6 | 2 | D05 | 72 | hr | 1657 | 5337 | 5505 | 0.9694 | 0.9562 |
| BT-20 | BMS345541 | 0.12 | uM | LJP6 | 3 | D05 | 72 | hr | 1657 | 5521 | 5505 | 1.0028 | 1.0040 |
| BT-20 | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 1657 | 1603 | 5505 | 0.2912 | -0.0142 |
| BT-20 | SNS-032 | 0.12 | uM | LJP6 | 2 | H17 | 72 | hr | 1657 | 1636 | 5505 | 0.2972 | -0.0056 |
| BT-20 | SNS-032 | 0.12 | uM | LJP6 | 3 | H17 | 72 | hr | 1657 | 1614 | 5505 | 0.2932 | -0.0114 |
| BT-20 | GDC-0980 | 0.12 | uM | LJP5 | 1 | K23 | 72 | hr | 1657 | 2044 | 5505 | 0.3713 | 0.1004 |
| BT-20 | GDC-0980 | 0.12 | uM | LJP5 | 2 | K23 | 72 | hr | 1657 | 2052 | 5505 | 0.3727 | 0.1025 |
| BT-20 | GDC-0980 | 0.12 | uM | LJP5 | 3 | K23 | 72 | hr | 1657 | 2068 | 5505 | 0.3756 | 0.1066 |
| BT-20 | NVP-AEW541 | 0.12 | uM | LJP5 | 1 | E17 | 72 | hr | 1657 | 6025 | 5505 | 1.0943 | 1.1350 |
| BT-20 | NVP-AEW541 | 0.12 | uM | LJP5 | 2 | E17 | 72 | hr | 1657 | 5711 | 5505 | 1.0373 | 1.0534 |
| BT-20 | NVP-AEW541 | 0.12 | uM | LJP5 | 3 | E17 | 72 | hr | 1657 | 5728 | 5505 | 1.0404 | 1.0578 |
| BT-20 | SB590885 | 0.12 | uM | LJP5 | 1 | L17 | 72 | hr | 1657 | 5308 | 5505 | 0.9641 | 0.9486 |
| BT-20 | SB590885 | 0.12 | uM | LJP5 | 2 | L17 | 72 | hr | 1657 | 5530 | 5505 | 1.0044 | 1.0063 |
| BT-20 | SB590885 | 0.12 | uM | LJP5 | 3 | L17 | 72 | hr | 1657 | 5341 | 5505 | 0.9701 | 0.9572 |
| BT-20 | PIK-93 | 0.12 | uM | LJP5 | 1 | K17 | 72 | hr | 1657 | 5500 | 5505 | 0.9990 | 0.9985 |
| BT-20 | PIK-93 | 0.12 | uM | LJP5 | 2 | K17 | 72 | hr | 1657 | 5590 | 5505 | 1.0153 | 1.0219 |
| BT-20 | PIK-93 | 0.12 | uM | LJP5 | 3 | K17 | 72 | hr | 1657 | 5517 | 5505 | 1.0021 | 1.0029 |
| BT-20 | KIN001-043 | 0.12 | uM | LJP6 | 1 | C11 | 72 | hr | 1657 | 5029 | 5505 | 0.9134 | 0.8761 |
| BT-20 | KIN001-043 | 0.12 | uM | LJP6 | 2 | C11 | 72 | hr | 1657 | 5012 | 5505 | 0.9103 | 0.8717 |
| BT-20 | KIN001-043 | 0.12 | uM | LJP6 | 3 | C11 | 72 | hr | 1657 | 5570 | 5505 | 1.0117 | 1.0167 |
| BT-20 | Alpelisib | 0.12 | uM | LJP5 | 1 | N05 | 72 | hr | 1657 | 4986 | 5505 | 0.9056 | 0.8650 |