LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 1 of 15: Cell count and relative growth within biological replicate 1. - Dataset (ID:20237)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1657 1661 5505 0.3017 0.0008
BT-20 Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1657 1732 5505 0.3146 0.0193
BT-20 Trametinib
0.37
uM
LJP5
 1
P22
 72
hr
 1657 4503 5505 0.8179 0.7394
BT-20 Trametinib
0.37
uM
LJP5
 2
P22
 72
hr
 1657 4431 5505 0.8048 0.7207
BT-20 Trametinib
0.37
uM
LJP5
 3
P22
 72
hr
 1657 4170 5505 0.7574 0.6529
BT-20 TWS119
0.37
uM
LJP5
 1
M04
 72
hr
 1657 5386 5505 0.9783 0.9689
BT-20 TWS119
0.37
uM
LJP5
 2
M04
 72
hr
 1657 5700 5505 1.0353 1.0505
BT-20 TWS119
0.37
uM
LJP5
 3
M04
 72
hr
 1657 5314 5505 0.9652 0.9502
BT-20 Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 1657 5720 5505 1.0389 1.0557
BT-20 Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 1657 5662 5505 1.0284 1.0406
BT-20 Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 1657 5249 5505 0.9534 0.9333
BT-20 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1657 5055 5505 0.9181 0.8829
BT-20 Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 1657 4361 5505 0.7921 0.7025
BT-20 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1657 4912 5505 0.8922 0.8457
BT-20 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1657 4661 5505 0.8466 0.7805
BT-20 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1657 4243 5505 0.7707 0.6719
BT-20 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1657 4391 5505 0.7975 0.7103
BT-20 WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 1657 2463 5505 0.4474 0.2093
BT-20 WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 1657 2454 5505 0.4457 0.2069
BT-20 WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 1657 2375 5505 0.4314 0.1864
BT-20 WZ3105
0.37
uM
LJP5
 1
D22
 72
hr
 1657 1887 5505 0.3427 0.0596
BT-20 WZ3105
0.37
uM
LJP5
 2
D22
 72
hr
 1657 1769 5505 0.3213 0.0289
BT-20 WZ3105
0.37
uM
LJP5
 3
D22
 72
hr
 1657 1935 5505 0.3515 0.0721
BT-20 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 1657 4531 5505 0.8230 0.7467
BT-20 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 1657 4441 5505 0.8066 0.7233