Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 21.0 87
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 21.0 92
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 19.0 60
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 25.0 71
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 24.0 62
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 19.0 85
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 18.0 87
RA1869 Poly(I:C) 2
ug/mL
 3
TRAIL
 20.0 82
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 22.0 61
N2759 Poly(I:C) 2
ug/mL
 3
TRAIL
 24.0 71
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 22.0 69
RA1931 Poly(I:C) 2
ug/mL
 3
TRAIL
 19.0 52
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 22.0 59
N2586 Poly(I:C) 2
ug/mL
 3
TRAIL
 23.0 62
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 43.0 83
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 44.0 66
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 48.0 93
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 35.0 81
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 50.0 69
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 43.5 92
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 47.0 85
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 49.0 86
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 44.0 61
RA1869 IL-1 alpha 100
ng/mL
 3
TRAIL
 21.0 82
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 48.0 54