Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 39.0 66
RA1869 TNF-a 100
ng/mL
 3
SCF
 36.0 70
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 42.0 76
N2759 TNF-a 100
ng/mL
 3
SCF
 44.5 46
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 44.5 52
RA1931 TNF-a 100
ng/mL
 3
SCF
 48.0 45
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
SCF
 44.0 65
N2586 TNF-a 100
ng/mL
 3
SCF
 45.0 55
RA1869 5z-7-oxozeaenol 0.6
uM
 3
SCF
 42.0 52
RA1869 IKK16 2.0
uM
 3
SCF
 39.0 67
N2759 5z-7-oxozeaenol 0.6
uM
 3
SCF
 31.0 63
N2759 IKK16 2.0
uM
 3
SCF
 38.0 62
RA1931 5z-7-oxozeaenol 0.6
uM
 3
SCF
 35.5 58
RA1931 IKK16 2.0
uM
 3
SCF
 39.0 82
N2586 5z-7-oxozeaenol 0.6
uM
 3
SCF
 35.0 68
N2586 IKK16 2.0
uM
 3
SCF
 35.0 80
RA1869 Tofacitinib 0.3
uM
 3
SCF
 36.0 47
RA1869 3
SCF
 37.0 62
N2759 Tofacitinib 0.3
uM
 3
SCF
 33.0 72
N2759 3
SCF
 37.0 54
RA1931 Tofacitinib 0.3
uM
 3
SCF
 37.5 66
RA1931 3
SCF
 42.0 58
N2586 Tofacitinib 0.3
uM
 3
SCF
 32.0 59
N2586 3
SCF
 43.0 53
RA1869 3
SCF
 41.0 46