Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SCF
 48.0 36
RA2708 TNF-a 100
ng/mL
 2
SCF
 46.0 54
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 62.5 64
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 63.5 64
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 54.0 75
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 52.0 69
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 51.0 45
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 47.0 50
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 63.0 53
RA2159 IL-1 alpha 100
ng/mL
 2
SCF
 63.5 50
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 53.0 47
N2645 IL-1 alpha 100
ng/mL
 2
SCF
 54.0 50
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
SCF
 52.0 63
RA2708 IL-1 alpha 100
ng/mL
 2
SCF
 50.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 57.0 53
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 54.0 45
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 48.5 72
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 47.0 60
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 37.0 64
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 43.0 63
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 54.0 51
RA2159 Poly(I:C) 2
ug/mL
 2
SCF
 43.0 43
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 40.0 49
N2645 Poly(I:C) 2
ug/mL
 2
SCF
 49.0 49
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
SCF
 41.5 44