Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Tofacitinib 0.3
uM
 2
IL3
 67.0 51
RA2708 2
IL3
 53.0 31
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL3
 62.5 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL3
 67.0 55
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL3
 54.0 62
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL3
 56.0 46
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL3
 62.5 58
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL3
 66.5 58
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL3
 44.0 45
RA2159 TNF-a 100
ng/mL
 2
IL3
 43.0 46
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL3
 56.0 29
N2645 TNF-a 100
ng/mL
 2
IL3
 52.0 42
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL3
 52.0 53
RA2708 TNF-a 100
ng/mL
 2
IL3
 64.0 30
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 101.5 62
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 85.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 109.0 59
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 106.5 46
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 101.5 52
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 97.0 41
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 92.0 39
RA2159 IL-1 alpha 100
ng/mL
 2
IL3
 80.5 50
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 91.5 26
N2645 IL-1 alpha 100
ng/mL
 2
IL3
 87.0 57
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL3
 108.0 59