Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 53.0 47
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 46.0 52
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 52.0 49
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 41.5 44
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 42.0 48
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 44.0 47
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL3
 60.0 52
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL3
 47.0 43
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 34.0 47
RA1869 TNF-a 100
ng/mL
 1
IL3
 74.0 46
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 49.0 43
N2759 TNF-a 100
ng/mL
 1
IL3
 69.0 44
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 41.0 39
RA1931 TNF-a 100
ng/mL
 1
IL3
 34.0 37
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL3
 56.0 35
N2586 TNF-a 100
ng/mL
 1
IL3
 54.5 62
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 83.0 31
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 66.0 53
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 63.5 48
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 81.0 43
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 83.0 36
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 79.0 30
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 73.0 50
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 62.0 45
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL3
 61.5 42