Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
b-NGF
 56.0 60
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
b-NGF
 45.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
b-NGF
 240.0 53
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
b-NGF
 269.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
b-NGF
 41.5 66
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
b-NGF
 24.0 51
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
b-NGF
 92.0 51
RA2159 TNF-a 100
ng/mL
 2
b-NGF
 91.0 41
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
b-NGF
 423.5 50
N2645 TNF-a 100
ng/mL
 2
b-NGF
 401.0 59
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
b-NGF
 59.0 49
RA2708 TNF-a 100
ng/mL
 2
b-NGF
 49.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 61.0 62
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 55.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 208.0 55
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 301.5 70
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 68.0 49
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 37.5 44
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 111.0 46
RA2159 IL-1 alpha 100
ng/mL
 2
b-NGF
 82.0 54
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 430.0 49
N2645 IL-1 alpha 100
ng/mL
 2
b-NGF
 464.0 52
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
b-NGF
 79.5 58
RA2708 IL-1 alpha 100
ng/mL
 2
b-NGF
 63.0 57
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
b-NGF
 54.5 50