Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
b-NGF
 49.0 45
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
b-NGF
 34.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
b-NGF
 116.5 58
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
b-NGF
 102.5 62
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
b-NGF
 53.0 62
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
b-NGF
 31.0 49
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 118.0 65
RA1869 TNF-a 100
ng/mL
 1
b-NGF
 149.0 49
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 104.0 46
N2759 TNF-a 100
ng/mL
 1
b-NGF
 106.0 56
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 166.0 48
RA1931 TNF-a 100
ng/mL
 1
b-NGF
 57.0 44
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
b-NGF
 104.0 47
N2586 TNF-a 100
ng/mL
 1
b-NGF
 87.0 44
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 62.0 45
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 60.0 66
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 48.0 53
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 62.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 92.0 45
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 49.5 38
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 53.0 49
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 35.0 43
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 141.0 39
RA1869 IL-1 alpha 100
ng/mL
 1
b-NGF
 144.0 51
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
b-NGF
 132.0 51