Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL18
 30.5 62
RA2159 IKK16 2.0
uM
 2
IL18
 30.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL18
 32.0 72
N2645 IKK16 2.0
uM
 2
IL18
 29.5 72
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL18
 25.0 66
RA2708 IKK16 2.0
uM
 2
IL18
 25.5 66
RA2159 Tofacitinib 0.3
uM
 2
IL18
 23.0 71
RA2159 2
IL18
 27.5 64
N2645 Tofacitinib 0.3
uM
 2
IL18
 28.0 56
N2645 2
IL18
 26.0 35
RA2708 Tofacitinib 0.3
uM
 2
IL18
 27.0 55
RA2708 2
IL18
 26.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL18
 30.0 69
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL18
 29.5 62
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL18
 34.0 58
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL18
 31.0 58
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL18
 27.0 58
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL18
 27.5 64
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL18
 24.0 43
RA2159 TNF-a 100
ng/mL
 2
IL18
 26.5 52
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL18
 31.5 38
N2645 TNF-a 100
ng/mL
 2
IL18
 27.0 75
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL18
 26.0 41
RA2708 TNF-a 100
ng/mL
 2
IL18
 28.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL18
 59.5 70