Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 24.0 59
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 33.0 87
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 26.0 70
RA1869 Poly(I:C) 2
ug/mL
 3
MIF
 29.0 61
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 27.0 51
N2759 Poly(I:C) 2
ug/mL
 3
MIF
 29.0 53
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 29.0 52
RA1931 Poly(I:C) 2
ug/mL
 3
MIF
 27.5 46
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIF
 28.0 55
N2586 Poly(I:C) 2
ug/mL
 3
MIF
 32.5 68
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 36.5 84
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 38.0 68
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 37.0 80
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 29.0 82
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 39.0 63
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 37.0 76
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 37.0 79
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 40.0 61
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 36.5 50
RA1869 IL-1 alpha 100
ng/mL
 3
MIF
 21.0 63
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 35.5 56
N2759 IL-1 alpha 100
ng/mL
 3
MIF
 35.0 59
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 41.0 54
RA1931 IL-1 alpha 100
ng/mL
 3
MIF
 36.0 60
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIF
 40.0 64