Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIF
 37.0 56
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MIF
 37.0 59
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIF
 39.5 40
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MIF
 161.0 55
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIF
 61.0 78
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIF
 28.0 55
RA2159 TNF-a 100
ng/mL
 2
MIF
 36.0 44
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIF
 32.0 47
N2645 TNF-a 100
ng/mL
 2
MIF
 37.0 63
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIF
 29.0 53
RA2708 TNF-a 100
ng/mL
 2
MIF
 27.0 48
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 45.0 71
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 43.0 69
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 52.0 71
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 46.0 81
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 41.0 64
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 47.0 54
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 44.0 48
RA2159 IL-1 alpha 100
ng/mL
 2
MIF
 40.5 50
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 43.0 45
N2645 IL-1 alpha 100
ng/mL
 2
MIF
 44.0 53
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIF
 37.5 54
RA2708 IL-1 alpha 100
ng/mL
 2
MIF
 42.0 50
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIF
 32.0 64
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIF
 28.0 74