Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 31.0 58
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 33.0 47
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 29.5 54
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 33.0 63
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 30.0 46
RA2159 Poly(I:C) 2
ug/mL
 4
TNFb
 34.0 37
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 34.5 50
N2645 Poly(I:C) 2
ug/mL
 4
TNFb
 35.0 51
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNFb
 29.5 40
RA2708 Poly(I:C) 2
ug/mL
 4
TNFb
 36.0 49
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 94.5 60
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 93.0 64
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 81.5 64
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 91.5 70
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 96.0 53
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 100.0 45
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 107.0 57
RA2159 IL-1 alpha 100
ng/mL
 4
TNFb
 95.0 43
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 113.5 40
N2645 IL-1 alpha 100
ng/mL
 4
TNFb
 98.5 50
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNFb
 97.0 41
RA2708 IL-1 alpha 100
ng/mL
 4
TNFb
 97.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNFb
 37.0 47
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 35.5 40
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNFb
 33.0 48