Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 62.0 68
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 97.0 61
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 85.5 74
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 101.0 55
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 96.5 86
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 89.0 49
RA1869 IL-1 alpha 100
ng/mL
 3
TNFb
 52.0 74
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 99.0 46
N2759 IL-1 alpha 100
ng/mL
 3
TNFb
 91.0 51
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 103.5 48
RA1931 IL-1 alpha 100
ng/mL
 3
TNFb
 97.5 52
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 100.0 53
N2586 IL-1 alpha 100
ng/mL
 3
TNFb
 105.5 60
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
TNFb
 28.0 63
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
TNFb
 40.0 61
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
TNFb
 30.5 64
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
TNFb
 40.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
TNFb
 41.0 57
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
TNFb
 39.0 53
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
TNFb
 39.0 49
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
TNFb
 34.0 57
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 29.0 73
RA1869 TNF-a 100
ng/mL
 3
TNFb
 34.5 74
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 35.5 74
N2759 TNF-a 100
ng/mL
 3
TNFb
 37.0 58