Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 35.0 51
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 44.0 62
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 34.0 53
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 43.5 50
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 38.0 47
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 45.0 31
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
LIF
 28.5 38
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
LIF
 52.5 48
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 72.0 64
RA1869 TNF-a 100
ng/mL
 3
LIF
 56.0 49
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 60.0 61
N2759 TNF-a 100
ng/mL
 3
LIF
 59.0 43
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 48.5 40
RA1931 TNF-a 100
ng/mL
 3
LIF
 49.0 41
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
LIF
 62.0 51
N2586 TNF-a 100
ng/mL
 3
LIF
 71.0 46
RA1869 5z-7-oxozeaenol 0.6
uM
 3
LIF
 38.0 42
RA1869 IKK16 2.0
uM
 3
LIF
 36.0 48
N2759 5z-7-oxozeaenol 0.6
uM
 3
LIF
 38.0 53
N2759 IKK16 2.0
uM
 3
LIF
 35.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
 3
LIF
 34.0 64
RA1931 IKK16 2.0
uM
 3
LIF
 39.0 57
N2586 5z-7-oxozeaenol 0.6
uM
 3
LIF
 38.0 50
N2586 IKK16 2.0
uM
 3
LIF
 38.5 52
RA1869 Tofacitinib 0.3
uM
 3
LIF
 33.0 32