Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
LIF
 41.0 46
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
LIF
 39.0 47
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
LIF
 40.5 32
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
LIF
 53.5 30
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 69.0 43
RA1869 TNF-a 100
ng/mL
 1
LIF
 77.5 38
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 59.5 34
N2759 TNF-a 100
ng/mL
 1
LIF
 54.0 43
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 54.0 35
RA1931 TNF-a 100
ng/mL
 1
LIF
 44.5 34
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 75.5 32
N2586 TNF-a 100
ng/mL
 1
LIF
 74.5 36
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 108.0 36
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 109.0 45
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 96.0 43
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 127.5 36
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 112.5 38
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 114.0 34
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 105.5 36
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 107.0 38
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 196.0 40
RA1869 IL-1 alpha 100
ng/mL
 1
LIF
 203.0 39
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 202.0 39
N2759 IL-1 alpha 100
ng/mL
 1
LIF
 201.0 37
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 212.0 31