Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 170.5 | 88 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 175.0 | 86 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 172.0 | 57 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 171.5 | 64 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 171.5 | 54 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 140.0 | 67 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 189.0 | 64 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 177.5 | 64 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 183.0 | 52 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 148.0 | 45 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 164.0 | 67 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 3 | IL12(p40) | 160.0 | 52 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 145.5 | 72 | |
| RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 145.0 | 78 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 129.0 | 83 | |
| N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 170.0 | 75 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 126.0 | 66 | |
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 157.0 | 71 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 95.0 | 65 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 156.0 | 55 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 136.0 | 74 | |
| RA1869 | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 134.0 | 52 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 158.0 | 72 | |
| N2759 | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 153.0 | 51 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | IL12(p40) | 130.0 | 57 |